AFP, His, Mouse

Alpha-fetoprotein is a shuttle protein that delivers nutrients through receptor-mediated endocytosis to embryotic cells. In adults, alpha-fetoprotein can shuttle drugs into alpha-fetoprotein receptor-positive myeloid-derived suppressor, regenerating and also cancer cells. Drugs with high-binding affinity to alpha-fetoprotein can activate or deplete targeted cells. Myeloid-derived suppressor cells activation leads to immune suppression that can be used for treating autoimmune diseases.

Price	$340.00
Cat. No.	Z05988-100
Size	100 μg 500 μg Buy in bulk
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Product Introduction Background Bottom Notes

Product Introduction

Species

Mouse

Protein Construction

AFP (Lys19-Val605)_x000D_ Accession # P02772	His
N-term	C-term

Purity

> 95% as determined by BisTris PAGE

Endotoxin Level

Less than 1EU per μg by the LAL method.

Expression System

HEK293

Theoretical Molecular Weight

66.40 kDa

Apparent Molecular Weight

Due to glycosylation, the protein migrates to 68-72 kDa based on Bis-Tris PAGE result.

Formulation

Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).

Reconstitution

Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.

Storage & Stability

Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.

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AFP, His, Mouse on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. »

The purity of AFP, His, Mouse is greater than 95% as determined by SEC-HPLC. »

Background

Target Background

Synonyms

Alpha-fetoprotein; Alpha-1-fetoprotein; Alpha-feto; AFP; HPAFP; AFPD; FETA

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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.