Catalog Products » BID, His, Mouse
Manual
Manual
COAs

BID, His, Mouse

Bid, BH3-interacting domain death agonist, was initially cloned based in its ability to interact with both Bcl-2 and Bax. Bid contains only the BH3 domain, which is required for its interaction with the Bcl-2 family proteins and for its pro-death activity. Bid is susceptible to proteolytic cleavage by caspases, calpains, Granzyme B and cathepsins. Bid is important to cell death mediated by these proteases and thus is the sentinel to protease-mediated death signals.
$430.00
Z06033-100

Ask us a question
Product Introduction
Species Mouse
Protein Construction
BID (Ala1-Ser195)_x000D_
Accession # EDK99650.1		 His
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE
Endotoxin Level Less than 1EU per μg by the LAL method.
Expression System E.coli
Theoretical Molecular Weight 22.72 kDa
Apparent Molecular Weight The protein has a predicted MW of 22.72 kDa same as Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.
Back

BID, His, Mouse

The purity of BID, His, Mouse is greater than 90% as determined by SEC-HPLC. »

BID, His, Mouse

BID, His, Mouse on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. »

BID, His, Mouse

BID, His, Mouse, His Tag immobilized on CM5 Chip can bind Human BCL2L1, His Tag with an affinity constant of 33.06 nM as determined in SPR assay (Biacore T200). »

<
>

Background
Target Background Bid, BH3-interacting domain death agonist, was initially cloned based in its ability to interact with both Bcl-2 and Bax. Bid contains only the BH3 domain, which is required for its interaction with the Bcl-2 family proteins and for its pro-death activity. Bid is susceptible to proteolytic cleavage by caspases, calpains, Granzyme B and cathepsins. Bid is important to cell death mediated by these proteases and thus is the sentinel to protease-mediated death signals.
Synonyms p22 BID; BID;
Back

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.