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IL-13Ra2, His, Mouse

Two type 1 membrane proteins belonging to the hemopoietin receptor family have been cloned and shown to bind IL-13 with differing affinities. The lower affinity IL-13 binding protein, previously designated IL-13 R alpha, IL-13 R alpha ' or NR4, is now referred to as IL-13 R alpha 1. The high-affinity IL-13 binding protein, previously also designated IL-13 R or IL-13 R alpha ', is now referred to as IL-13 R alpha 2.
$370.00
Z06185-100

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Product Introduction
Species Mouse
Protein Construction
IL-13Ra2 (Leu22-Lys334)_x000D_
Accession # O88786-1		 His
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA. Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 37.55 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 45-60 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.
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IL-13Ra2, His, Mouse

Loaded Human IL-13, hFc Tag on ProA-Biosensor can bind IL-13Ra2, His, Mouse, His Tag with an affinity constant of 1.88 nM as determined in BLI assay (Gator® Prime). »

IL-13Ra2, His, Mouse

Immobilized IL-13Ra2, His, Mouse, His Tag at 2 μg/ml (100 μl/well) on the plate. Dose response curve for Human IL-13, hFc Tag with the EC50 of 10.2ng/ml determined by ELISA. »

IL-13Ra2, His, Mouse

The purity of IL-13Ra2, His, Mouse is greater than 95% as determined by SEC-HPLC. »

IL-13Ra2, His, Mouse

IL-13Ra2, His, Mouse on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. »

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Background
Target Background Two type 1 membrane proteins belonging to the hemopoietin receptor family have been cloned and shown to bind IL-13 with differing affinities. The lower affinity IL-13 binding protein, previously designated IL-13 R alpha, IL-13 R alpha ' or NR4, is now referred to as IL-13 R alpha 1. The high-affinity IL-13 binding protein, previously also designated IL-13 R or IL-13 R alpha ', is now referred to as IL-13 R alpha 2.
Synonyms CD213a2; IL-13 R alpha 2; IL13BP; IL13R; IL13RA2; IL-13Ra2
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.