OX40/TNFRSF4/CD134, His & Avi, Mouse

Tumor necrosis factor receptor superfamily, member 4 (TNFRSF4), also known as CD134 and OX40 receptor. OX40 is a secondary co-stimulatory immune checkpoint molecule, expressed after 24 to 72 hours following activation; its ligand, OX40L, is also not expressed on resting antigen presenting cells, but is following their activation.

Price	$260.00
Cat. No.	Z06296-100
Size	100 μg 500 μg Buy in bulk
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Product Introduction Background Bottom Notes

Product Introduction

Species

Mouse

Protein Construction

OX40/TNFRSF4/CD134 (Val20-Pro211) Accession # P47741	His	Avi
N-term		C-term

Purity

> 95% as determined by BisTris PAGE

Endotoxin Level

Less than 1EU per ug by the LAL method.

Biological Activity

Measured by its binding ability in a functional ELISA. Test result was comparable to standard batch.

Expression System

HEK293

Theoretical Molecular Weight

24.2 kDa

Apparent Molecular Weight

Due to glycosylation, the protein migrates to 50-60 kDa based on Bis-Tris PAGE result.

Formulation

Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).

Reconstitution

Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.

Storage & Stability

Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.

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Immobilized Mouse OX40 Ligand, hFc Tag at 5 μg /ml (100 μl/well) on the plate. Dose response curve for OX40/TNFRSF4/CD134, His & Avi, Mouse, His Tag with the EC50 of 0.91 μg /ml determined by ELISA. »

The purity of OX40/TNFRSF4/CD134, His & Avi, Mouse is greater than 90% as determined by SEC-HPLC. »

OX40/TNFRSF4/CD134, His & Avi, Mouse on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. »

Background

Target Background	Tumor necrosis factor receptor superfamily, member 4 (TNFRSF4), also known as CD134 and OX40 receptor. OX40 is a secondary co-stimulatory immune checkpoint molecule, expressed after 24 to 72 hours following activation; its ligand, OX40L, is also not expressed on resting antigen presenting cells, but is following their activation.
Synonyms	CD134; OX40; OX40L receptor; TNFRSF4; ACT-135; Ly-70; OX40 homologue; TXGP1L; IMD16

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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.