Catalog Products » HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQV) Tetramer, His & Avi, Human
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HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQV) Tetramer, His & Avi, Human

NY-ESO-1 or New York esophageal squamous cell carcinoma 1 is a well-known cancer-testis antigen (CTAs) with re-expression in numerous cancer types. Its ability to elicit spontaneous humoral and cellular immune responses, together with its restricted expression pattern, have rendered it a good candidate target for cancer immunotherapy.
$1120.00
Z06583-100

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Product Introduction
Species Human
Protein Construction
HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQV) Tetramer[Gly25-Thr305(HLA-A*02:01), Ile21-Met119(B2M) and SLLMWITQV peptide]
Accession # A0A140T913(HLA-A*02:01)&P61769(B2M)&SLLMWITQV		 His Avi
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA.Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 258 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 260-265 kDa under Non reducing (N) condition based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.
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HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQV) Tetramer, His & Avi, Human

Immobilized HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQV) Tetramer, His & Avi, Human, His Tag at 5 μg/ml (100 μl/well) on the plate. Dose response curve for Anti-HLA-A*02:01&B2M&NY-ESO-1 Antibody, hFc Tag with the EC50 of 1.0 ng/ml determined by ELISA. »

HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQV) Tetramer, His & Avi, Human

The purity of HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQV) Tetramer, His & Avi, Human is greater than 95% as determined by SEC-HPLC. »

HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQV) Tetramer, His & Avi, Human

HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQV) Tetramer, His & Avi, Human on Bis-Tris PAGE under Non reducing (N) condition. The purity is greater than 95%. »

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Background
Target Background NY-ESO-1 or New York esophageal squamous cell carcinoma 1 is a well-known cancer-testis antigen (CTAs) with re-expression in numerous cancer types. Its ability to elicit spontaneous humoral and cellular immune responses, together with its restricted expression pattern, have rendered it a good candidate target for cancer immunotherapy.
Synonyms MHC; MY-ESO-1; CT6.1; LAGE-2; CTAG1; CTAG1B; ESO1CTAG; LAGE2A; NY-ESO-1; CTAG1A
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.