Catalog Products » Other Products » Endotoxin Detection and Removal System » ToxinSensorTM Gel Clot Endotoxin Assay Kit
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L00351
1 Kit
$90

ToxinSensorTM Gel Clot Endotoxin Assay Kit


Description
ToxinSensorTM Gel Clot Endotoxin Assay Kit is intended as an In Vitro end-product endotoxin test for human and animal parenteral drugs, biological products, and medical devices. The Limulus Amebocyte Lysate (LAL) test is a qualitative test for Gram-negative bacterial endotoxin. Limulus Amebocyte Lysate as supplied is to be reconstituted with LAL Reagent Water and then mixed in equal parts with the solution being tested. After incubation, and in the presence of endotoxin, gelation occurs; in the absence of endotoxin, gelation does not occur.
The procedures described herein conform with those described in the FDA Guideline. Similar performance requirements for gel clot assays have been published and are updated regularly in the United States Pharmacopeia.

Key Features
  • Good reproducibility
  • Competitive price
  • Ready-to-use reagents and materials, such as tips, Endotoxin-free tubes, etc

Technical Manual
  • TECHNICAL MANUAL: 5291_20080806231639.PDF (PDF)


  • Components
    LAL Reagent Water 4 x 10 ml
    Limulus Amebocyte Lysate (LAL) 2 x 2 ml
    E. coli Endotoxin Standard 2 x 0.5 EU
    Endotoxin-free tubes 5 x 16 tubes
    Tips 200 μl 1 box
    Tips 1000 μl 2 bags
    ToxinSensorTM Rack 1


    Document


    References

    • Moshiri A., et al. Role of Tissue-Engineered Artificial Tendon in Healing of a Large Achilles Tendon Defect Model in Rabbits. J Am Coll Surg. 2013 Jun 29. pii: S1072-7515(13)00312-8.
    • Moshiri A., et al. Effectiveness of hybridized nano- and microstructure biodegradable, biocompatible, collagen-based, three-dimensional bioimplants in repair of a large tendon-defect model in rabbits. J Tissue Eng Regen Med. 2013 May 2. doi: 10.1002/term.1740.
    • Chellan B., et al. LIGHT/TNFSR14 Can Regulate Hepatic Lipase Expression by Hepatocytes Independent of T Cells and Kupffer Cells. PLoS One. 2013;8(1):e54719.
    • Zhong D., et al. The Salmonella Type III Secretion System Inner Rod Protein PrgJ is Partially Folded. J Biol Chem. 2012 Jul 20;287(30):25303-11.
    • Wang QY., et al. Cytokine Tumor Necrosis Factor Alpha Induces Intestinal Epithelial Barrier Dysfunction. Cytokine. 2012 May;58(2):226-30.
    • Kathryn Gibson, et al. Proteomic Analysis of Neorickettsia sennetsu Surface-Exposed Proteins and Porin Activity of the Major Surface Protein P51. J Bacteriol. 2010 Nov;192(22):5898-905.
    • Usuki S., et al. Development of a novel therapy for Lipo-oligosaccharide-induced experimental neuritis: use of peptide glycomimics. J Neurochem. 2010 Apr;113(2):351-62.
    • Than NG., et al. A primate subfamily of galectins expressed at the maternal-fetal interface that promote immune cell death. Proc Natl Acad Sci USA. 2009 Jun 16;106(24):9731-6.

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