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CHO-K1/BB1 Stable Cell Line


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M00254 CHO-K1/BB1 Stable Cell Line
2 vials
$8500.00


Description The bombesin receptor family is a member of the G protein-coupled receptor superfamily and consists of three subtypes of receptors: BB1 (neuromedin B receptor), BB2 (gastrin-releasing peptide receptor), and BB3. These receptors are widely distributed in mammals especially in the CNS and gastrointestinal tract and have numerous effects both physiologically and in pathologic processes including having an autocrine growth action on normal tissues and tumors; potent CNS effects (satiety, circadian rhythm, various behaviors); and potent effects in the immune, gastrointestinal, respiratory and urogenital systems.
The human BB1 receptor has a greater than 100-fold higher affinity for neuromedin B than gastrin-releasing peptide. Interaction of ligand and BB1 activates the Gαq/11 pathway and increase the intracellular calcium concentration. GenScript's BB1-expressing stable cell line was made in CHO-K1 host cell and optimized for calcium assays.
Application Functional assay for BB1 receptor

Storage Liquid nitrogen immediately upon delivery

CHO-K1/BB1 Stable Cell Line
CHO-K1/BB1 Stable Cell Line

CHO-K1/BB1 Stable Cell Line

CHO-K1/BB1 Stable Cell Line


Cat. No.
Product Name
Size
Price
Quantity
RP10507 Neuromedin B
1 mg
$38.00
RP10791-0.5 Gastrin-Releasing Peptide, human
0.5 mg
$90.00
RP11157-5 Bombesin
5 mg
$90.00
RP11157-1 Bombesin
1 mg
$24.00


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