CHO-K1/GPR40-GFP
*This product has been discontinued!*
Free fatty acid G protein coupled receptor family consists of four members and plays significant roles in nutrition regulation. GPR40 and GPR120 are activated by medium and long-chain FFAs, whereas GPR41 and GPR43 are activated by short-chain FFAs. GPR40, preferentially expressed in pancreatic beta-cells, mediates the majority of the effects of FFAs on insulin secretion. Research findings have shown that GPR40 as a potential therapeutic target plays an important role in the chain of events linking obesity and type2 diabetes.
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