CPSF3 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	CPSF3
Entrez Gene ID	51692
Full Name	cleavage and polyadenylation specific factor 3
Synonyms	CPSF-73,CPSF73
General protein information	Preferred Names cleavage and polyadenylation specific factor 3 Names cleavage and polyadenylation specificity factor subunit 3 cleavage and polyadenylation specific factor 3, 73kDa mRNA 3'-end-processing endonuclease CPSF-73
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 2 Map Location: 2p25.1
Summary	This gene encodes a member of the metallo-beta-lactamase family. The encoded protein is a 73kDa subunit of the cleavage and polyadenylation specificity factor and functions as an endonuclease that recognizes the pre-mRNA 3'-cleavage site AAUAAA prior to polyadenylation. It also cleaves after the pre-mRNA sequence ACCCA during histone 3'-end pre-mRNA processing. [provided by RefSeq, Oct 2012].
Disorder MIM:	606029

mRNA and Protein(s)

mRNA	Protein	Name
NM_001321833.1	NP_001308762.1	cleavage and polyadenylation specificity factor subunit 3 isoform b
NM_016207.4	NP_057291.1	cleavage and polyadenylation specificity factor subunit 3 isoform a
NM_016207.3	NP_057291.1	cleavage and polyadenylation specificity factor subunit 3 isoform a
NM_001321834.1	NP_001308763.1	cleavage and polyadenylation specificity factor subunit 3 isoform b
NM_001321835.1	NP_001308764.1	cleavage and polyadenylation specificity factor subunit 3 isoform c
NM_001321836.1	NP_001308765.1	cleavage and polyadenylation specificity factor subunit 3 isoform d

Pathways from BioSystems

Homologies

Homo sapiens (human)	CPSF3	NP_057291.1
Caenorhabditis elegans (roundworm)	cpsf-3	NP_502553.2
Oryza sativa (rice)	Os03g0852900	NP_001051928.1
Canis lupus familiaris (dog)	CPSF3	XP_005630164.1
Mus musculus (house mouse)	Cpsf3	NP_061283.2
Danio rerio (zebrafish)	cpsf3	NP_001003836.1
Kluyveromyces lactis	KLLA0C04598g	XP_452404.1
Eremothecium gossypii	AGOS_AGR279C	NP_986945.2
Magnaporthe oryzae (rice blast fungus)	MGG_01804	XP_003714815.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP001224	XP_321933.5
Saccharomyces cerevisiae (baker's yeast)	YSH1	NP_013379.1
Schizosaccharomyces pombe (fission yeast)	ysh1	NP_594263.2
Arabidopsis thaliana (thale cress)	CPSF73-I	NP_001031215.1
Pan troglodytes (chimpanzee)	CPSF3	NP_001233296.1
	CPSF3	XP_002799184.1
Bos taurus (cattle)	CPSF3	NP_776709.1
Rattus norvegicus (Norway rat)	Cpsf3	NP_001025201.1
Gallus gallus (chicken)	CPSF3	XP_419942.4
Drosophila melanogaster (fruit fly)	Cpsf73	NP_650738.1
Neurospora crassa	NCU03479	XP_956368.1
Xenopus tropicalis (tropical clawed frog)	cpsf3	NP_001006770.1

Gene Ontology
Bibliography

Related articles in PubMed

A complex containing the CPSF73 endonuclease and other polyadenylation factors associates with U7 snRNP and is recruited to histone pre-mRNA for 3'-end processing.
Yang XC, Sabath I, D?bski J, Kaus-Drobek M, Dadlez M, Marzluff WF, Dominski Z
Molecular and cellular biology33(1)28-37(2013 Jan)

The poly A polymerase Star-PAP controls 3'-end cleavage by promoting CPSF interaction and specificity toward the pre-mRNA.
Laishram RS, Anderson RA
The EMBO journal29(24)4132-45(2010 Dec)

Studies of the 5' exonuclease and endonuclease activities of CPSF-73 in histone pre-mRNA processing.
Yang XC, Sullivan KD, Marzluff WF, Dominski Z
Molecular and cellular biology29(1)31-42(2009 Jan)

The tumor suppressor Cdc73 functionally associates with CPSF and CstF 3' mRNA processing factors.
Rozenblatt-Rosen O, Nagaike T, Francis JM, Kaneko S, Glatt KA, Hughes CM, LaFramboise T, Manley JL, Meyerson M
Proceedings of the National Academy of Sciences of the United States of America106(3)755-60(2009 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

the molecular mechanism that recruits the CPSF73 endonuclease to histone pre-mRNAs
Title: A complex containing the CPSF73 endonuclease and other polyadenylation factors associates with U7 snRNP and is recruited to histone pre-mRNA for 3'-end processing.

The data support a model where Star-PAP binds to the pre-mRNA, recruits the CPSF complex to the 3'-end of pre-mRNA and then defines cleavage by CPSF 73 and subsequent polyadenylation of its target mRNAs.
Title: The poly A polymerase Star-PAP controls 3'-end cleavage by promoting CPSF interaction and specificity toward the pre-mRNA.

CSR1 appears to induce cell death through a novel mechanism by hijacking a critical RNA processing enzyme CPSF3.
Title: CSR1 induces cell death through inactivation of CPSF3.

Degradation of the downstream cleavage product (DCP) does not depend on the Xrn2 5' exonuclease, suggesting that CPSF-73 degrades the DCP both in vitro and in vivo.
Title: Studies of the 5' exonuclease and endonuclease activities of CPSF-73 in histone pre-mRNA processing.

The tumor suppressor Cdc73 functionally associates with CPSF and CstF 3' mRNA processing factors.
Title: The tumor suppressor Cdc73 functionally associates with CPSF and CstF 3' mRNA processing factors.

The following CPSF3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CPSF3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu00542	NM_016207.4 Latest version!	Homo sapiens cleavage and polyadenylation specific factor 3 (CPSF3), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu102071	NM_001321836.1 Latest version!	Homo sapiens cleavage and polyadenylation specific factor 3 (CPSF3), transcript variant 5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$279.50-$391.30 $559.00
OHu35200	NM_001321833.1 Latest version!	Homo sapiens cleavage and polyadenylation specific factor 3 (CPSF3), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$307.30 $439.00
OHu35200	NM_001321834.1 Latest version!	Homo sapiens cleavage and polyadenylation specific factor 3 (CPSF3), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$307.30 $439.00
OHu101725	NM_001321835.1 Latest version!	Homo sapiens cleavage and polyadenylation specific factor 3 (CPSF3), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
View Old Accession Versions >>
OHu00542	NM_016207.3	Homo sapiens cleavage and polyadenylation specific factor 3 (CPSF3), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CPSF3 ( NM_016207.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_057291.1 Homo sapiens cleavage and polyadenylation specific factor 3 (CPSF3), transcript variant 1, mRNA.

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CloneID	OHu00542
Clone ID Related Accession (Same CDS sequence)	NM_016207.4 , NM_016207.3
Accession Version	NM_016207.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2055bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Homo sapiens(human)
Product	cleavage and polyadenylation specificity factor subunit 3 isoform a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC420903.1, BC020211.1 and AA635764.1. On Nov 22, 2018 this sequence version replaced NM_016207.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660803.92137.1, SRR1803615.243113.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000238112.8/ ENSP00000238112.3 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGTCTGCGA TTCCTGCTGA GGAGAGCGAC CAGCTGCTGA TCCGACCCCT TGGAGCTGGG 
CAAGAAGTAG GAAGATCATG TATTATTCTC GAGTTCAAAG GAAGAAAAAT AATGCTCGAC 
TGTGGGATCC ACCCTGGCCT AGAAGGAATG GATGCTCTTC CTTATATTGA TTTAATTGAC 
CCAGCTGAGA TTGATCTCCT ATTAATTAGT CATTTCCATT TGGATCACTG TGGAGCTCTG 
CCCTGGTTTC TACAGAAGAC AAGTTTCAAA GGAAGAACAT TTATGACTCA TGCCACAAAA 
GCTATTTATA GATGGCTTCT TTCTGATTAT GTCAAAGTTA GTAACATATC AGCAGACGAC 
ATGCTGTATA CCGAGACAGA TTTGGAAGAA AGCATGGACA AAATTGAAAC TATCAACTTT 
CATGAAGTTA AGGAAGTTGC GGGAATCAAG TTTTGGTGTT ACCATGCAGG TCACGTCCTA 
GGAGCCGCCA TGTTCATGAT TGAGATCGCA GGCGTGAAGC TTTTGTACAC TGGTGATTTC 
TCAAGACAAG AAGATAGGCA CTTAATGGCA GCTGAAATTC CTAATATTAA GCCTGATATT 
CTTATCATTG AATCTACTTA TGGGACCCAT ATCCATGAGA AACGTGAAGA GCGAGAAGCA 
AGATTCTGTA ACACTGTCCA CGATATTGTA AACAGAGGAG GCAGGGGTCT CATTCCTGTC 
TTTGCTCTTG GAAGGGCTCA GGAGCTGCTC TTGATTCTAG ATGAGTACTG GCAGAATCAC 
CCAGAACTAC ATGACATTCC AATATACTAT GCATCATCTT TGGCCAAGAA GTGTATGGCA 
GTGTACCAGA CATATGTAAA TGCCATGAAT GACAAAATCC GCAAACAGAT CAACATCAAT 
AATCCCTTTG TTTTCAAACA CATTAGTAAC CTCAAGAGCA TGGATCATTT TGATGACATT 
GGTCCCAGTG TTGTAATGGC CTCCCCAGGC ATGATGCAAA GTGGCTTATC CAGAGAATTA 
TTTGAAAGCT GGTGTACTGA TAAGAGGAAT GGTGTCATTA TAGCGGGATA CTGTGTAGAA 
GGGACACTTG CCAAGCACAT CATGTCTGAA CCTGAAGAAA TCACTACTAT GTCTGGACAG 
AAGTTACCAC TGAAAATGTC TGTTGATTAC ATTTCTTTCT CAGCTCACAC GGATTACCAG 
CAAACCAGTG AATTTATTCG TGCTTTGAAA CCGCCTCATG TGATTTTAGT CCATGGAGAA 
CAGAATGAAA TGGCCAGATT GAAAGCAGCA CTGATTCGAG AATATGAAGA TAACGATGAA 
GTTCACATAG AGGTTCATAA TCCTCGGAAT ACAGAAGCAG TGACCTTAAA CTTCAGAGGA 
GAAAAACTAG CCAAGGTTAT GGGATTTTTA GCAGACAAAA AACCAGAACA AGGCCAGCGG 
GTCTCAGGAA TACTTGTTAA AAGAAACTTT AATTATCACA TACTTTCTCC TTGCGACCTG 
TCCAATTATA CTGACCTGGC CATGAGCACG GTGAAGCAGA CCCAAGCCAT TCCATATACT 
GGTCCCTTTA ATTTGCTCTG TTACCAGCTG CAGAAATTGA CAGGTGATGT GGAAGAATTA 
GAAATTCAAG AAAAACCTGC TCTGAAAGTG TTCAAAAATA TTACTGTAAT ACAAGAACCA 
GGCATGGTGG TATTAGAATG GCTGGCAAAC CCTTCTAATG ATATGTATGC AGATACAGTA 
ACAACTGTGA TATTGGAAGT TCAGTCAAAT CCCAAAATAA GAAAAGGTGC AGTACAGAAG 
GTTTCTAAAA AATTAGAAAT GCACGTTTAC AGCAAGAGGT TGGAGATCAT GCTCCAGGAC 
ATATTTGGAG AAGACTGTGT AAGTGTAAAG GATGACTCTA TTCTTAGCGT CACAGTGGAC 
GGGAAAACTG CCAACCTTAA CTTGGAGACA CGGACTGTAG AATGTGAAGA GGGAAGTGAA 
GACGATGAAT CCCTCCGAGA AATGGTGGAG CTGGCTGCAC AGAGACTGTA CGAGGCCCTG 
ACGCCAGTTC ACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_057291.1
CDS	121..2175
Translation	MSAIPAEESDQLLIRPLGAGQEVGRSCIILEFKGRKIMLDCGIHPGLEGMDALPYIDLIDPAEIDLLLISHFHLDHCGALPWFLQKTSFKGRTFMTHATKAIYRWLLSDYVKVSNISADDMLYTETDLEESMDKIETINFHEVKEVAGIKFWCYHAGHVLGAAMFMIEIAGVKLLYTGDFSRQEDRHLMAAEIPNIKPDILIIESTYGTHIHEKREEREARFCNTVHDIVNRGGRGLIPVFALGRAQELLLILDEYWQNHPELHDIPIYYASSLAKKCMAVYQTYVNAMNDKIRKQININNPFVFKHISNLKSMDHFDDIGPSVVMASPGMMQSGLSRELFESWCTDKRNGVIIAGYCVEGTLAKHIMSEPEEITTMSGQKLPLKMSVDYISFSAHTDYQQTSEFIRALKPPHVILVHGEQNEMARLKAALIREYEDNDEVHIEVHNPRNTEAVTLNFRGEKLAKVMGFLADKKPEQGQRVSGILVKRNFNYHILSPCDLSNYTDLAMSTVKQTQAIPYTGPFNLLCYQLQKLTGDVEELEIQEKPALKVFKNITVIQEPGMVVLEWLANPSNDMYADTVTTVILEVQSNPKIRKGAVQKVSKKLEMHVYSKRLEIMLQDIFGEDCVSVKDDSILSVTVDGKTANLNLETRTVECEEGSEDDESLREMVELAAQRLYEALTPVH

Target ORF information:

RefSeq Version	NM_016207.4
Organism	Homo sapiens(human)
Definition	Homo sapiens cleavage and polyadenylation specific factor 3 (CPSF3), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_016207.4

ORF Insert Sequence:

ATGTCTGCGA TTCCTGCTGA GGAGAGCGAC CAGCTGCTGA TCCGACCCCT TGGAGCTGGG 
CAAGAAGTAG GAAGATCATG TATTATTCTC GAGTTCAAAG GAAGAAAAAT AATGCTCGAC 
TGTGGGATCC ACCCTGGCCT AGAAGGAATG GATGCTCTTC CTTATATTGA TTTAATTGAC 
CCAGCTGAGA TTGATCTCCT ATTAATTAGT CATTTCCATT TGGATCACTG TGGAGCTCTG 
CCCTGGTTTC TACAGAAGAC AAGTTTCAAA GGAAGAACAT TTATGACTCA TGCCACAAAA 
GCTATTTATA GATGGCTTCT TTCTGATTAT GTCAAAGTTA GTAACATATC AGCAGACGAC 
ATGCTGTATA CCGAGACAGA TTTGGAAGAA AGCATGGACA AAATTGAAAC TATCAACTTT 
CATGAAGTTA AGGAAGTTGC GGGAATCAAG TTTTGGTGTT ACCATGCAGG TCACGTCCTA 
GGAGCCGCCA TGTTCATGAT TGAGATCGCA GGCGTGAAGC TTTTGTACAC TGGTGATTTC 
TCAAGACAAG AAGATAGGCA CTTAATGGCA GCTGAAATTC CTAATATTAA GCCTGATATT 
CTTATCATTG AATCTACTTA TGGGACCCAT ATCCATGAGA AACGTGAAGA GCGAGAAGCA 
AGATTCTGTA ACACTGTCCA CGATATTGTA AACAGAGGAG GCAGGGGTCT CATTCCTGTC 
TTTGCTCTTG GAAGGGCTCA GGAGCTGCTC TTGATTCTAG ATGAGTACTG GCAGAATCAC 
CCAGAACTAC ATGACATTCC AATATACTAT GCATCATCTT TGGCCAAGAA GTGTATGGCA 
GTGTACCAGA CATATGTAAA TGCCATGAAT GACAAAATCC GCAAACAGAT CAACATCAAT 
AATCCCTTTG TTTTCAAACA CATTAGTAAC CTCAAGAGCA TGGATCATTT TGATGACATT 
GGTCCCAGTG TTGTAATGGC CTCCCCAGGC ATGATGCAAA GTGGCTTATC CAGAGAATTA 
TTTGAAAGCT GGTGTACTGA TAAGAGGAAT GGTGTCATTA TAGCGGGATA CTGTGTAGAA 
GGGACACTTG CCAAGCACAT CATGTCTGAA CCTGAAGAAA TCACTACTAT GTCTGGACAG 
AAGTTACCAC TGAAAATGTC TGTTGATTAC ATTTCTTTCT CAGCTCACAC GGATTACCAG 
CAAACCAGTG AATTTATTCG TGCTTTGAAA CCGCCTCATG TGATTTTAGT CCATGGAGAA 
CAGAATGAAA TGGCCAGATT GAAAGCAGCA CTGATTCGAG AATATGAAGA TAACGATGAA 
GTTCACATAG AGGTTCATAA TCCTCGGAAT ACAGAAGCAG TGACCTTAAA CTTCAGAGGA 
GAAAAACTAG CCAAGGTTAT GGGATTTTTA GCAGACAAAA AACCAGAACA AGGCCAGCGG 
GTCTCAGGAA TACTTGTTAA AAGAAACTTT AATTATCACA TACTTTCTCC TTGCGACCTG 
TCCAATTATA CTGACCTGGC CATGAGCACG GTGAAGCAGA CCCAAGCCAT TCCATATACT 
GGTCCCTTTA ATTTGCTCTG TTACCAGCTG CAGAAATTGA CAGGTGATGT GGAAGAATTA 
GAAATTCAAG AAAAACCTGC TCTGAAAGTG TTCAAAAATA TTACTGTAAT ACAAGAACCA 
GGCATGGTGG TATTAGAATG GCTGGCAAAC CCTTCTAATG ATATGTATGC AGATACAGTA 
ACAACTGTGA TATTGGAAGT TCAGTCAAAT CCCAAAATAA GAAAAGGTGC AGTACAGAAG 
GTTTCTAAAA AATTAGAAAT GCACGTTTAC AGCAAGAGGT TGGAGATCAT GCTCCAGGAC 
ATATTTGGAG AAGACTGTGT AAGTGTAAAG GATGACTCTA TTCTTAGCGT CACAGTGGAC 
GGGAAAACTG CCAACCTTAA CTTGGAGACA CGGACTGTAG AATGTGAAGA GGGAAGTGAA 
GACGATGAAT CCCTCCGAGA AATGGTGGAG CTGGCTGCAC AGAGACTGTA CGAGGCCCTG 
ACGCCAGTTC ACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CPSF3 ( NM_016207.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_057291.1 Homo sapiens cleavage and polyadenylation specific factor 3 (CPSF3), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu00542
Clone ID Related Accession (Same CDS sequence)	NM_016207.4 , NM_016207.3
Accession Version	NM_016207.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2055bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-02
Organism	Homo sapiens(human)
Product	cleavage and polyadenylation specificity factor subunit 3 isoform a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC420903.1, BC020211.1 and AA635764.1. On Oct 16, 2012 this sequence version replaced NM_016207.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803617.116634.1, SRR1660803.243321.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCTGCGA TTCCTGCTGA GGAGAGCGAC CAGCTGCTGA TCCGACCCCT TGGAGCTGGG 
CAAGAAGTAG GAAGATCATG TATTATTCTC GAGTTCAAAG GAAGAAAAAT AATGCTCGAC 
TGTGGGATCC ACCCTGGCCT AGAAGGAATG GATGCTCTTC CTTATATTGA TTTAATTGAC 
CCAGCTGAGA TTGATCTCCT ATTAATTAGT CATTTCCATT TGGATCACTG TGGAGCTCTG 
CCCTGGTTTC TACAGAAGAC AAGTTTCAAA GGAAGAACAT TTATGACTCA TGCCACAAAA 
GCTATTTATA GATGGCTTCT TTCTGATTAT GTCAAAGTTA GTAACATATC AGCAGACGAC 
ATGCTGTATA CCGAGACAGA TTTGGAAGAA AGCATGGACA AAATTGAAAC TATCAACTTT 
CATGAAGTTA AGGAAGTTGC GGGAATCAAG TTTTGGTGTT ACCATGCAGG TCACGTCCTA 
GGAGCCGCCA TGTTCATGAT TGAGATCGCA GGCGTGAAGC TTTTGTACAC TGGTGATTTC 
TCAAGACAAG AAGATAGGCA CTTAATGGCA GCTGAAATTC CTAATATTAA GCCTGATATT 
CTTATCATTG AATCTACTTA TGGGACCCAT ATCCATGAGA AACGTGAAGA GCGAGAAGCA 
AGATTCTGTA ACACTGTCCA CGATATTGTA AACAGAGGAG GCAGGGGTCT CATTCCTGTC 
TTTGCTCTTG GAAGGGCTCA GGAGCTGCTC TTGATTCTAG ATGAGTACTG GCAGAATCAC 
CCAGAACTAC ATGACATTCC AATATACTAT GCATCATCTT TGGCCAAGAA GTGTATGGCA 
GTGTACCAGA CATATGTAAA TGCCATGAAT GACAAAATCC GCAAACAGAT CAACATCAAT 
AATCCCTTTG TTTTCAAACA CATTAGTAAC CTCAAGAGCA TGGATCATTT TGATGACATT 
GGTCCCAGTG TTGTAATGGC CTCCCCAGGC ATGATGCAAA GTGGCTTATC CAGAGAATTA 
TTTGAAAGCT GGTGTACTGA TAAGAGGAAT GGTGTCATTA TAGCGGGATA CTGTGTAGAA 
GGGACACTTG CCAAGCACAT CATGTCTGAA CCTGAAGAAA TCACTACTAT GTCTGGACAG 
AAGTTACCAC TGAAAATGTC TGTTGATTAC ATTTCTTTCT CAGCTCACAC GGATTACCAG 
CAAACCAGTG AATTTATTCG TGCTTTGAAA CCGCCTCATG TGATTTTAGT CCATGGAGAA 
CAGAATGAAA TGGCCAGATT GAAAGCAGCA CTGATTCGAG AATATGAAGA TAACGATGAA 
GTTCACATAG AGGTTCATAA TCCTCGGAAT ACAGAAGCAG TGACCTTAAA CTTCAGAGGA 
GAAAAACTAG CCAAGGTTAT GGGATTTTTA GCAGACAAAA AACCAGAACA AGGCCAGCGG 
GTCTCAGGAA TACTTGTTAA AAGAAACTTT AATTATCACA TACTTTCTCC TTGCGACCTG 
TCCAATTATA CTGACCTGGC CATGAGCACG GTGAAGCAGA CCCAAGCCAT TCCATATACT 
GGTCCCTTTA ATTTGCTCTG TTACCAGCTG CAGAAATTGA CAGGTGATGT GGAAGAATTA 
GAAATTCAAG AAAAACCTGC TCTGAAAGTG TTCAAAAATA TTACTGTAAT ACAAGAACCA 
GGCATGGTGG TATTAGAATG GCTGGCAAAC CCTTCTAATG ATATGTATGC AGATACAGTA 
ACAACTGTGA TATTGGAAGT TCAGTCAAAT CCCAAAATAA GAAAAGGTGC AGTACAGAAG 
GTTTCTAAAA AATTAGAAAT GCACGTTTAC AGCAAGAGGT TGGAGATCAT GCTCCAGGAC 
ATATTTGGAG AAGACTGTGT AAGTGTAAAG GATGACTCTA TTCTTAGCGT CACAGTGGAC 
GGGAAAACTG CCAACCTTAA CTTGGAGACA CGGACTGTAG AATGTGAAGA GGGAAGTGAA 
GACGATGAAT CCCTCCGAGA AATGGTGGAG CTGGCTGCAC AGAGACTGTA CGAGGCCCTG 
ACGCCAGTTC ACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_057291.1
CDS	238..2292
Translation	MSAIPAEESDQLLIRPLGAGQEVGRSCIILEFKGRKIMLDCGIHPGLEGMDALPYIDLIDPAEIDLLLISHFHLDHCGALPWFLQKTSFKGRTFMTHATKAIYRWLLSDYVKVSNISADDMLYTETDLEESMDKIETINFHEVKEVAGIKFWCYHAGHVLGAAMFMIEIAGVKLLYTGDFSRQEDRHLMAAEIPNIKPDILIIESTYGTHIHEKREEREARFCNTVHDIVNRGGRGLIPVFALGRAQELLLILDEYWQNHPELHDIPIYYASSLAKKCMAVYQTYVNAMNDKIRKQININNPFVFKHISNLKSMDHFDDIGPSVVMASPGMMQSGLSRELFESWCTDKRNGVIIAGYCVEGTLAKHIMSEPEEITTMSGQKLPLKMSVDYISFSAHTDYQQTSEFIRALKPPHVILVHGEQNEMARLKAALIREYEDNDEVHIEVHNPRNTEAVTLNFRGEKLAKVMGFLADKKPEQGQRVSGILVKRNFNYHILSPCDLSNYTDLAMSTVKQTQAIPYTGPFNLLCYQLQKLTGDVEELEIQEKPALKVFKNITVIQEPGMVVLEWLANPSNDMYADTVTTVILEVQSNPKIRKGAVQKVSKKLEMHVYSKRLEIMLQDIFGEDCVSVKDDSILSVTVDGKTANLNLETRTVECEEGSEDDESLREMVELAAQRLYEALTPVH

Target ORF information:

RefSeq Version	NM_016207.3
Organism	Homo sapiens(human)
Definition	Homo sapiens cleavage and polyadenylation specific factor 3 (CPSF3), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_016207.3

ORF Insert Sequence:

ATGTCTGCGA TTCCTGCTGA GGAGAGCGAC CAGCTGCTGA TCCGACCCCT TGGAGCTGGG 
CAAGAAGTAG GAAGATCATG TATTATTCTC GAGTTCAAAG GAAGAAAAAT AATGCTCGAC 
TGTGGGATCC ACCCTGGCCT AGAAGGAATG GATGCTCTTC CTTATATTGA TTTAATTGAC 
CCAGCTGAGA TTGATCTCCT ATTAATTAGT CATTTCCATT TGGATCACTG TGGAGCTCTG 
CCCTGGTTTC TACAGAAGAC AAGTTTCAAA GGAAGAACAT TTATGACTCA TGCCACAAAA 
GCTATTTATA GATGGCTTCT TTCTGATTAT GTCAAAGTTA GTAACATATC AGCAGACGAC 
ATGCTGTATA CCGAGACAGA TTTGGAAGAA AGCATGGACA AAATTGAAAC TATCAACTTT 
CATGAAGTTA AGGAAGTTGC GGGAATCAAG TTTTGGTGTT ACCATGCAGG TCACGTCCTA 
GGAGCCGCCA TGTTCATGAT TGAGATCGCA GGCGTGAAGC TTTTGTACAC TGGTGATTTC 
TCAAGACAAG AAGATAGGCA CTTAATGGCA GCTGAAATTC CTAATATTAA GCCTGATATT 
CTTATCATTG AATCTACTTA TGGGACCCAT ATCCATGAGA AACGTGAAGA GCGAGAAGCA 
AGATTCTGTA ACACTGTCCA CGATATTGTA AACAGAGGAG GCAGGGGTCT CATTCCTGTC 
TTTGCTCTTG GAAGGGCTCA GGAGCTGCTC TTGATTCTAG ATGAGTACTG GCAGAATCAC 
CCAGAACTAC ATGACATTCC AATATACTAT GCATCATCTT TGGCCAAGAA GTGTATGGCA 
GTGTACCAGA CATATGTAAA TGCCATGAAT GACAAAATCC GCAAACAGAT CAACATCAAT 
AATCCCTTTG TTTTCAAACA CATTAGTAAC CTCAAGAGCA TGGATCATTT TGATGACATT 
GGTCCCAGTG TTGTAATGGC CTCCCCAGGC ATGATGCAAA GTGGCTTATC CAGAGAATTA 
TTTGAAAGCT GGTGTACTGA TAAGAGGAAT GGTGTCATTA TAGCGGGATA CTGTGTAGAA 
GGGACACTTG CCAAGCACAT CATGTCTGAA CCTGAAGAAA TCACTACTAT GTCTGGACAG 
AAGTTACCAC TGAAAATGTC TGTTGATTAC ATTTCTTTCT CAGCTCACAC GGATTACCAG 
CAAACCAGTG AATTTATTCG TGCTTTGAAA CCGCCTCATG TGATTTTAGT CCATGGAGAA 
CAGAATGAAA TGGCCAGATT GAAAGCAGCA CTGATTCGAG AATATGAAGA TAACGATGAA 
GTTCACATAG AGGTTCATAA TCCTCGGAAT ACAGAAGCAG TGACCTTAAA CTTCAGAGGA 
GAAAAACTAG CCAAGGTTAT GGGATTTTTA GCAGACAAAA AACCAGAACA AGGCCAGCGG 
GTCTCAGGAA TACTTGTTAA AAGAAACTTT AATTATCACA TACTTTCTCC TTGCGACCTG 
TCCAATTATA CTGACCTGGC CATGAGCACG GTGAAGCAGA CCCAAGCCAT TCCATATACT 
GGTCCCTTTA ATTTGCTCTG TTACCAGCTG CAGAAATTGA CAGGTGATGT GGAAGAATTA 
GAAATTCAAG AAAAACCTGC TCTGAAAGTG TTCAAAAATA TTACTGTAAT ACAAGAACCA 
GGCATGGTGG TATTAGAATG GCTGGCAAAC CCTTCTAATG ATATGTATGC AGATACAGTA 
ACAACTGTGA TATTGGAAGT TCAGTCAAAT CCCAAAATAA GAAAAGGTGC AGTACAGAAG 
GTTTCTAAAA AATTAGAAAT GCACGTTTAC AGCAAGAGGT TGGAGATCAT GCTCCAGGAC 
ATATTTGGAG AAGACTGTGT AAGTGTAAAG GATGACTCTA TTCTTAGCGT CACAGTGGAC 
GGGAAAACTG CCAACCTTAA CTTGGAGACA CGGACTGTAG AATGTGAAGA GGGAAGTGAA 
GACGATGAAT CCCTCCGAGA AATGGTGGAG CTGGCTGCAC AGAGACTGTA CGAGGCCCTG 
ACGCCAGTTC ACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CPSF3 ( NM_001321836.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001308765.1 Homo sapiens cleavage and polyadenylation specific factor 3 (CPSF3), transcript variant 5, mRNA.

Price & Availability↑

CloneID	OHu102071
Clone ID Related Accession (Same CDS sequence)	NM_001321836.1
Accession Version	NM_001321836.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2067bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-28
Organism	Homo sapiens(human)
Product	cleavage and polyadenylation specificity factor subunit 3 isoform d
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC420903.1, DA455023.1, BG773037.1, AC080162.7, BC014106.1 and AA635764.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. COMPLETENESS: complete on the 3' end.

ATGAGAATGA AGATTGAGAA GTTGGCCAAG GAGCAAACCC TCGGAATATC AACATTTAAA 
GGTGGAGCTG GGCAAGAAGT AGGAAGATCA TGTATTATTC TCGAGTTCAA AGGAAGAAAA 
ATAATGCTCG ACTGTGGGAT CCACCCTGGC CTAGAAGGAA TGGATGCTCT TCCTTATATT 
GATTTAATTG ACCCAGCTGA GATTGATCTC CTATTAATTA GTCATTTCCA TTTGGATCAC 
TGTGGAGCTC TGCCCTGGTT TCTACAGAAG ACAAGTTTCA AAGGAAGAAC ATTTATGACT 
CATGCCACAA AAGCTATTTA TAGATGGCTT CTTTCTGATT ATGTCAAAGT TAGTAACATA 
TCAGCAGACG ACATGCTGTA TACCGAGACA GATTTGGAAG AAAGCATGGA CAAAATTGAA 
ACTATCAACT TTCATGAAGT TAAGGAAGTT GCGGGAATCA AGTTTTGGTG TTACCATGCA 
GGTCACGTCC TAGGAGCCGC CATGTTCATG ATTGAGATCG CAGGCGTGAA GCTTTTGTAC 
ACTGGTGATT TCTCAAGACA AGAAGATAGG CACTTAATGG CAGCTGAAAT TCCTAATATT 
AAGCCTGATA TTCTTATCAT TGAATCTACT TATGGGACCC ATATCCATGA GAAACGTGAA 
GAGCGAGAAG CAAGATTCTG TAACACTGTC CACGATATTG TAAACAGAGG AGGCAGGGGT 
CTCATTCCTG TCTTTGCTCT TGGAAGGGCT CAGGAGCTGC TCTTGATTCT AGATGAGTAC 
TGGCAGAATC ACCCAGAACT ACATGACATT CCAATATACT ATGCATCATC TTTGGCCAAG 
AAGTGTATGG CAGTGTACCA GACATATGTA AATGCCATGA ATGACAAAAT CCGCAAACAG 
ATCAACATCA ATAATCCCTT TGTTTTCAAA CACATTAGTA ACCTCAAGAG CATGGATCAT 
TTTGATGACA TTGGTCCCAG TGTTGTAATG GCCTCCCCAG GCATGATGCA AAGTGGCTTA 
TCCAGAGAAT TATTTGAAAG CTGGTGTACT GATAAGAGGA ATGGTGTCAT TATAGCGGGA 
TACTGTGTAG AAGGGACACT TGCCAAGCAC ATCATGTCTG AACCTGAAGA AATCACTACT 
ATGTCTGGAC AGAAGTTACC ACTGAAAATG TCTGTTGATT ACATTTCTTT CTCAGCTCAC 
ACGGATTACC AGCAAACCAG TGAATTTATT CGTGCTTTGA AACCGCCTCA TGTGATTTTA 
GTCCATGGAG AACAGAATGA AATGGCCAGA TTGAAAGCAG CACTGATTCG AGAATATGAA 
GATAACGATG AAGTTCACAT AGAGGTTCAT AATCCTCGGA ATACAGAAGC AGTGACCTTA 
AACTTCAGAG GAGAAAAACT AGCCAAGGTT ATGGGATTTT TAGCAGACAA AAAACCAGAA 
CAAGGCCAGC GGGTCTCAGG AATACTTGTT AAAAGAAACT TTAATTATCA CATACTTTCT 
CCTTGCGACC TGTCCAATTA TACTGACCTG GCCATGAGCA CGGTGAAGCA GACCCAAGCC 
ATTCCATATA CTGGTCCCTT TAATTTGCTC TGTTACCAGC TGCAGAAATT GACAGGTGAT 
GTGGAAGAAT TAGAAATTCA AGAAAAACCT GCTCTGAAAG TGTTCAAAAA TATTACTGTA 
ATACAAGAAC CAGGCATGGT GGTATTAGAA TGGCTGGCAA ACCCTTCTAA TGATATGTAT 
GCAGATACAG TAACAACTGT GATATTGGAA GTTCAGTCAA ATCCCAAAAT AAGAAAAGGT 
GCAGTACAGA AGGTTTCTAA AAAATTAGAA ATGCACGTTT ACAGCAAGAG GTTGGAGATC 
ATGCTCCAGG ACATATTTGG AGAAGACTGT GTAAGTGTAA AGGATGACTC TATTCTTAGC 
GTCACAGTGG ACGGGAAAAC TGCCAACCTT AACTTGGAGA CACGGACTGT AGAATGTGAA 
GAGGGAAGTG AAGACGATGA ATCCCTCCGA GAAATGGTGG AGCTGGCTGC ACAGAGACTG 
TACGAGGCCC TGACGCCAGT TCACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001308765.1
CDS	545..2611
Translation	MRMKIEKLAKEQTLGISTFKGGAGQEVGRSCIILEFKGRKIMLDCGIHPGLEGMDALPYIDLIDPAEIDLLLISHFHLDHCGALPWFLQKTSFKGRTFMTHATKAIYRWLLSDYVKVSNISADDMLYTETDLEESMDKIETINFHEVKEVAGIKFWCYHAGHVLGAAMFMIEIAGVKLLYTGDFSRQEDRHLMAAEIPNIKPDILIIESTYGTHIHEKREEREARFCNTVHDIVNRGGRGLIPVFALGRAQELLLILDEYWQNHPELHDIPIYYASSLAKKCMAVYQTYVNAMNDKIRKQININNPFVFKHISNLKSMDHFDDIGPSVVMASPGMMQSGLSRELFESWCTDKRNGVIIAGYCVEGTLAKHIMSEPEEITTMSGQKLPLKMSVDYISFSAHTDYQQTSEFIRALKPPHVILVHGEQNEMARLKAALIREYEDNDEVHIEVHNPRNTEAVTLNFRGEKLAKVMGFLADKKPEQGQRVSGILVKRNFNYHILSPCDLSNYTDLAMSTVKQTQAIPYTGPFNLLCYQLQKLTGDVEELEIQEKPALKVFKNITVIQEPGMVVLEWLANPSNDMYADTVTTVILEVQSNPKIRKGAVQKVSKKLEMHVYSKRLEIMLQDIFGEDCVSVKDDSILSVTVDGKTANLNLETRTVECEEGSEDDESLREMVELAAQRLYEALTPVH

Target ORF information:

RefSeq Version	NM_001321836.1
Organism	Homo sapiens(human)
Definition	Homo sapiens cleavage and polyadenylation specific factor 3 (CPSF3), transcript variant 5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001321836.1

ORF Insert Sequence:

ATGAGAATGA AGATTGAGAA GTTGGCCAAG GAGCAAACCC TCGGAATATC AACATTTAAA 
GGTGGAGCTG GGCAAGAAGT AGGAAGATCA TGTATTATTC TCGAGTTCAA AGGAAGAAAA 
ATAATGCTCG ACTGTGGGAT CCACCCTGGC CTAGAAGGAA TGGATGCTCT TCCTTATATT 
GATTTAATTG ACCCAGCTGA GATTGATCTC CTATTAATTA GTCATTTCCA TTTGGATCAC 
TGTGGAGCTC TGCCCTGGTT TCTACAGAAG ACAAGTTTCA AAGGAAGAAC ATTTATGACT 
CATGCCACAA AAGCTATTTA TAGATGGCTT CTTTCTGATT ATGTCAAAGT TAGTAACATA 
TCAGCAGACG ACATGCTGTA TACCGAGACA GATTTGGAAG AAAGCATGGA CAAAATTGAA 
ACTATCAACT TTCATGAAGT TAAGGAAGTT GCGGGAATCA AGTTTTGGTG TTACCATGCA 
GGTCACGTCC TAGGAGCCGC CATGTTCATG ATTGAGATCG CAGGCGTGAA GCTTTTGTAC 
ACTGGTGATT TCTCAAGACA AGAAGATAGG CACTTAATGG CAGCTGAAAT TCCTAATATT 
AAGCCTGATA TTCTTATCAT TGAATCTACT TATGGGACCC ATATCCATGA GAAACGTGAA 
GAGCGAGAAG CAAGATTCTG TAACACTGTC CACGATATTG TAAACAGAGG AGGCAGGGGT 
CTCATTCCTG TCTTTGCTCT TGGAAGGGCT CAGGAGCTGC TCTTGATTCT AGATGAGTAC 
TGGCAGAATC ACCCAGAACT ACATGACATT CCAATATACT ATGCATCATC TTTGGCCAAG 
AAGTGTATGG CAGTGTACCA GACATATGTA AATGCCATGA ATGACAAAAT CCGCAAACAG 
ATCAACATCA ATAATCCCTT TGTTTTCAAA CACATTAGTA ACCTCAAGAG CATGGATCAT 
TTTGATGACA TTGGTCCCAG TGTTGTAATG GCCTCCCCAG GCATGATGCA AAGTGGCTTA 
TCCAGAGAAT TATTTGAAAG CTGGTGTACT GATAAGAGGA ATGGTGTCAT TATAGCGGGA 
TACTGTGTAG AAGGGACACT TGCCAAGCAC ATCATGTCTG AACCTGAAGA AATCACTACT 
ATGTCTGGAC AGAAGTTACC ACTGAAAATG TCTGTTGATT ACATTTCTTT CTCAGCTCAC 
ACGGATTACC AGCAAACCAG TGAATTTATT CGTGCTTTGA AACCGCCTCA TGTGATTTTA 
GTCCATGGAG AACAGAATGA AATGGCCAGA TTGAAAGCAG CACTGATTCG AGAATATGAA 
GATAACGATG AAGTTCACAT AGAGGTTCAT AATCCTCGGA ATACAGAAGC AGTGACCTTA 
AACTTCAGAG GAGAAAAACT AGCCAAGGTT ATGGGATTTT TAGCAGACAA AAAACCAGAA 
CAAGGCCAGC GGGTCTCAGG AATACTTGTT AAAAGAAACT TTAATTATCA CATACTTTCT 
CCTTGCGACC TGTCCAATTA TACTGACCTG GCCATGAGCA CGGTGAAGCA GACCCAAGCC 
ATTCCATATA CTGGTCCCTT TAATTTGCTC TGTTACCAGC TGCAGAAATT GACAGGTGAT 
GTGGAAGAAT TAGAAATTCA AGAAAAACCT GCTCTGAAAG TGTTCAAAAA TATTACTGTA 
ATACAAGAAC CAGGCATGGT GGTATTAGAA TGGCTGGCAA ACCCTTCTAA TGATATGTAT 
GCAGATACAG TAACAACTGT GATATTGGAA GTTCAGTCAA ATCCCAAAAT AAGAAAAGGT 
GCAGTACAGA AGGTTTCTAA AAAATTAGAA ATGCACGTTT ACAGCAAGAG GTTGGAGATC 
ATGCTCCAGG ACATATTTGG AGAAGACTGT GTAAGTGTAA AGGATGACTC TATTCTTAGC 
GTCACAGTGG ACGGGAAAAC TGCCAACCTT AACTTGGAGA CACGGACTGT AGAATGTGAA 
GAGGGAAGTG AAGACGATGA ATCCCTCCGA GAAATGGTGG AGCTGGCTGC ACAGAGACTG 
TACGAGGCCC TGACGCCAGT TCACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CPSF3 ( NM_001321833.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001308762.1 Homo sapiens cleavage and polyadenylation specific factor 3 (CPSF3), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu35200
Clone ID Related Accession (Same CDS sequence)	NM_001321833.1 , NM_001321834.1
Accession Version	NM_001321833.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1944bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-28
Organism	Homo sapiens(human)
Product	cleavage and polyadenylation specificity factor subunit 3 isoform b
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC420903.1, DA455023.1, BC014106.1 and AA635764.1. On Mar 31, 2016 this sequence version replaced XM_005246168.1. Transcript Variant: This variant (2) and variant 3 both encode the same isoform (b). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803615.165614.1, SRR1803617.276114.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCTCGACT GTGGGATCCA CCCTGGCCTA GAAGGAATGG ATGCTCTTCC TTATATTGAT 
TTAATTGACC CAGCTGAGAT TGATCTCCTA TTAATTAGTC ATTTCCATTT GGATCACTGT 
GGAGCTCTGC CCTGGTTTCT ACAGAAGACA AGTTTCAAAG GAAGAACATT TATGACTCAT 
GCCACAAAAG CTATTTATAG ATGGCTTCTT TCTGATTATG TCAAAGTTAG TAACATATCA 
GCAGACGACA TGCTGTATAC CGAGACAGAT TTGGAAGAAA GCATGGACAA AATTGAAACT 
ATCAACTTTC ATGAAGTTAA GGAAGTTGCG GGAATCAAGT TTTGGTGTTA CCATGCAGGT 
CACGTCCTAG GAGCCGCCAT GTTCATGATT GAGATCGCAG GCGTGAAGCT TTTGTACACT 
GGTGATTTCT CAAGACAAGA AGATAGGCAC TTAATGGCAG CTGAAATTCC TAATATTAAG 
CCTGATATTC TTATCATTGA ATCTACTTAT GGGACCCATA TCCATGAGAA ACGTGAAGAG 
CGAGAAGCAA GATTCTGTAA CACTGTCCAC GATATTGTAA ACAGAGGAGG CAGGGGTCTC 
ATTCCTGTCT TTGCTCTTGG AAGGGCTCAG GAGCTGCTCT TGATTCTAGA TGAGTACTGG 
CAGAATCACC CAGAACTACA TGACATTCCA ATATACTATG CATCATCTTT GGCCAAGAAG 
TGTATGGCAG TGTACCAGAC ATATGTAAAT GCCATGAATG ACAAAATCCG CAAACAGATC 
AACATCAATA ATCCCTTTGT TTTCAAACAC ATTAGTAACC TCAAGAGCAT GGATCATTTT 
GATGACATTG GTCCCAGTGT TGTAATGGCC TCCCCAGGCA TGATGCAAAG TGGCTTATCC 
AGAGAATTAT TTGAAAGCTG GTGTACTGAT AAGAGGAATG GTGTCATTAT AGCGGGATAC 
TGTGTAGAAG GGACACTTGC CAAGCACATC ATGTCTGAAC CTGAAGAAAT CACTACTATG 
TCTGGACAGA AGTTACCACT GAAAATGTCT GTTGATTACA TTTCTTTCTC AGCTCACACG 
GATTACCAGC AAACCAGTGA ATTTATTCGT GCTTTGAAAC CGCCTCATGT GATTTTAGTC 
CATGGAGAAC AGAATGAAAT GGCCAGATTG AAAGCAGCAC TGATTCGAGA ATATGAAGAT 
AACGATGAAG TTCACATAGA GGTTCATAAT CCTCGGAATA CAGAAGCAGT GACCTTAAAC 
TTCAGAGGAG AAAAACTAGC CAAGGTTATG GGATTTTTAG CAGACAAAAA ACCAGAACAA 
GGCCAGCGGG TCTCAGGAAT ACTTGTTAAA AGAAACTTTA ATTATCACAT ACTTTCTCCT 
TGCGACCTGT CCAATTATAC TGACCTGGCC ATGAGCACGG TGAAGCAGAC CCAAGCCATT 
CCATATACTG GTCCCTTTAA TTTGCTCTGT TACCAGCTGC AGAAATTGAC AGGTGATGTG 
GAAGAATTAG AAATTCAAGA AAAACCTGCT CTGAAAGTGT TCAAAAATAT TACTGTAATA 
CAAGAACCAG GCATGGTGGT ATTAGAATGG CTGGCAAACC CTTCTAATGA TATGTATGCA 
GATACAGTAA CAACTGTGAT ATTGGAAGTT CAGTCAAATC CCAAAATAAG AAAAGGTGCA 
GTACAGAAGG TTTCTAAAAA ATTAGAAATG CACGTTTACA GCAAGAGGTT GGAGATCATG 
CTCCAGGACA TATTTGGAGA AGACTGTGTA AGTGTAAAGG ATGACTCTAT TCTTAGCGTC 
ACAGTGGACG GGAAAACTGC CAACCTTAAC TTGGAGACAC GGACTGTAGA ATGTGAAGAG 
GGAAGTGAAG ACGATGAATC CCTCCGAGAA ATGGTGGAGC TGGCTGCACA GAGACTGTAC 
GAGGCCCTGA CGCCAGTTCA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001308762.1
CDS	578..2521
Translation	MLDCGIHPGLEGMDALPYIDLIDPAEIDLLLISHFHLDHCGALPWFLQKTSFKGRTFMTHATKAIYRWLLSDYVKVSNISADDMLYTETDLEESMDKIETINFHEVKEVAGIKFWCYHAGHVLGAAMFMIEIAGVKLLYTGDFSRQEDRHLMAAEIPNIKPDILIIESTYGTHIHEKREEREARFCNTVHDIVNRGGRGLIPVFALGRAQELLLILDEYWQNHPELHDIPIYYASSLAKKCMAVYQTYVNAMNDKIRKQININNPFVFKHISNLKSMDHFDDIGPSVVMASPGMMQSGLSRELFESWCTDKRNGVIIAGYCVEGTLAKHIMSEPEEITTMSGQKLPLKMSVDYISFSAHTDYQQTSEFIRALKPPHVILVHGEQNEMARLKAALIREYEDNDEVHIEVHNPRNTEAVTLNFRGEKLAKVMGFLADKKPEQGQRVSGILVKRNFNYHILSPCDLSNYTDLAMSTVKQTQAIPYTGPFNLLCYQLQKLTGDVEELEIQEKPALKVFKNITVIQEPGMVVLEWLANPSNDMYADTVTTVILEVQSNPKIRKGAVQKVSKKLEMHVYSKRLEIMLQDIFGEDCVSVKDDSILSVTVDGKTANLNLETRTVECEEGSEDDESLREMVELAAQRLYEALTPVH

Target ORF information:

RefSeq Version	NM_001321833.1
Organism	Homo sapiens(human)
Definition	Homo sapiens cleavage and polyadenylation specific factor 3 (CPSF3), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001321833.1

ORF Insert Sequence:

ATGCTCGACT GTGGGATCCA CCCTGGCCTA GAAGGAATGG ATGCTCTTCC TTATATTGAT 
TTAATTGACC CAGCTGAGAT TGATCTCCTA TTAATTAGTC ATTTCCATTT GGATCACTGT 
GGAGCTCTGC CCTGGTTTCT ACAGAAGACA AGTTTCAAAG GAAGAACATT TATGACTCAT 
GCCACAAAAG CTATTTATAG ATGGCTTCTT TCTGATTATG TCAAAGTTAG TAACATATCA 
GCAGACGACA TGCTGTATAC CGAGACAGAT TTGGAAGAAA GCATGGACAA AATTGAAACT 
ATCAACTTTC ATGAAGTTAA GGAAGTTGCG GGAATCAAGT TTTGGTGTTA CCATGCAGGT 
CACGTCCTAG GAGCCGCCAT GTTCATGATT GAGATCGCAG GCGTGAAGCT TTTGTACACT 
GGTGATTTCT CAAGACAAGA AGATAGGCAC TTAATGGCAG CTGAAATTCC TAATATTAAG 
CCTGATATTC TTATCATTGA ATCTACTTAT GGGACCCATA TCCATGAGAA ACGTGAAGAG 
CGAGAAGCAA GATTCTGTAA CACTGTCCAC GATATTGTAA ACAGAGGAGG CAGGGGTCTC 
ATTCCTGTCT TTGCTCTTGG AAGGGCTCAG GAGCTGCTCT TGATTCTAGA TGAGTACTGG 
CAGAATCACC CAGAACTACA TGACATTCCA ATATACTATG CATCATCTTT GGCCAAGAAG 
TGTATGGCAG TGTACCAGAC ATATGTAAAT GCCATGAATG ACAAAATCCG CAAACAGATC 
AACATCAATA ATCCCTTTGT TTTCAAACAC ATTAGTAACC TCAAGAGCAT GGATCATTTT 
GATGACATTG GTCCCAGTGT TGTAATGGCC TCCCCAGGCA TGATGCAAAG TGGCTTATCC 
AGAGAATTAT TTGAAAGCTG GTGTACTGAT AAGAGGAATG GTGTCATTAT AGCGGGATAC 
TGTGTAGAAG GGACACTTGC CAAGCACATC ATGTCTGAAC CTGAAGAAAT CACTACTATG 
TCTGGACAGA AGTTACCACT GAAAATGTCT GTTGATTACA TTTCTTTCTC AGCTCACACG 
GATTACCAGC AAACCAGTGA ATTTATTCGT GCTTTGAAAC CGCCTCATGT GATTTTAGTC 
CATGGAGAAC AGAATGAAAT GGCCAGATTG AAAGCAGCAC TGATTCGAGA ATATGAAGAT 
AACGATGAAG TTCACATAGA GGTTCATAAT CCTCGGAATA CAGAAGCAGT GACCTTAAAC 
TTCAGAGGAG AAAAACTAGC CAAGGTTATG GGATTTTTAG CAGACAAAAA ACCAGAACAA 
GGCCAGCGGG TCTCAGGAAT ACTTGTTAAA AGAAACTTTA ATTATCACAT ACTTTCTCCT 
TGCGACCTGT CCAATTATAC TGACCTGGCC ATGAGCACGG TGAAGCAGAC CCAAGCCATT 
CCATATACTG GTCCCTTTAA TTTGCTCTGT TACCAGCTGC AGAAATTGAC AGGTGATGTG 
GAAGAATTAG AAATTCAAGA AAAACCTGCT CTGAAAGTGT TCAAAAATAT TACTGTAATA 
CAAGAACCAG GCATGGTGGT ATTAGAATGG CTGGCAAACC CTTCTAATGA TATGTATGCA 
GATACAGTAA CAACTGTGAT ATTGGAAGTT CAGTCAAATC CCAAAATAAG AAAAGGTGCA 
GTACAGAAGG TTTCTAAAAA ATTAGAAATG CACGTTTACA GCAAGAGGTT GGAGATCATG 
CTCCAGGACA TATTTGGAGA AGACTGTGTA AGTGTAAAGG ATGACTCTAT TCTTAGCGTC 
ACAGTGGACG GGAAAACTGC CAACCTTAAC TTGGAGACAC GGACTGTAGA ATGTGAAGAG 
GGAAGTGAAG ACGATGAATC CCTCCGAGAA ATGGTGGAGC TGGCTGCACA GAGACTGTAC 
GAGGCCCTGA CGCCAGTTCA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CPSF3 ( NM_001321834.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001308763.1 Homo sapiens cleavage and polyadenylation specific factor 3 (CPSF3), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu35200
Clone ID Related Accession (Same CDS sequence)	NM_001321833.1 , NM_001321834.1
Accession Version	NM_001321834.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1944bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-28
Organism	Homo sapiens(human)
Product	cleavage and polyadenylation specificity factor subunit 3 isoform b
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC420903.1, DA455023.1, BC014106.1 and AA635764.1. On Mar 31, 2016 this sequence version replaced XM_011510362.1. Transcript Variant: This variant (3) and variant 2 both encode the same isoform (b). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803616.127989.1, BC014106.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968189, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCTCGACT GTGGGATCCA CCCTGGCCTA GAAGGAATGG ATGCTCTTCC TTATATTGAT 
TTAATTGACC CAGCTGAGAT TGATCTCCTA TTAATTAGTC ATTTCCATTT GGATCACTGT 
GGAGCTCTGC CCTGGTTTCT ACAGAAGACA AGTTTCAAAG GAAGAACATT TATGACTCAT 
GCCACAAAAG CTATTTATAG ATGGCTTCTT TCTGATTATG TCAAAGTTAG TAACATATCA 
GCAGACGACA TGCTGTATAC CGAGACAGAT TTGGAAGAAA GCATGGACAA AATTGAAACT 
ATCAACTTTC ATGAAGTTAA GGAAGTTGCG GGAATCAAGT TTTGGTGTTA CCATGCAGGT 
CACGTCCTAG GAGCCGCCAT GTTCATGATT GAGATCGCAG GCGTGAAGCT TTTGTACACT 
GGTGATTTCT CAAGACAAGA AGATAGGCAC TTAATGGCAG CTGAAATTCC TAATATTAAG 
CCTGATATTC TTATCATTGA ATCTACTTAT GGGACCCATA TCCATGAGAA ACGTGAAGAG 
CGAGAAGCAA GATTCTGTAA CACTGTCCAC GATATTGTAA ACAGAGGAGG CAGGGGTCTC 
ATTCCTGTCT TTGCTCTTGG AAGGGCTCAG GAGCTGCTCT TGATTCTAGA TGAGTACTGG 
CAGAATCACC CAGAACTACA TGACATTCCA ATATACTATG CATCATCTTT GGCCAAGAAG 
TGTATGGCAG TGTACCAGAC ATATGTAAAT GCCATGAATG ACAAAATCCG CAAACAGATC 
AACATCAATA ATCCCTTTGT TTTCAAACAC ATTAGTAACC TCAAGAGCAT GGATCATTTT 
GATGACATTG GTCCCAGTGT TGTAATGGCC TCCCCAGGCA TGATGCAAAG TGGCTTATCC 
AGAGAATTAT TTGAAAGCTG GTGTACTGAT AAGAGGAATG GTGTCATTAT AGCGGGATAC 
TGTGTAGAAG GGACACTTGC CAAGCACATC ATGTCTGAAC CTGAAGAAAT CACTACTATG 
TCTGGACAGA AGTTACCACT GAAAATGTCT GTTGATTACA TTTCTTTCTC AGCTCACACG 
GATTACCAGC AAACCAGTGA ATTTATTCGT GCTTTGAAAC CGCCTCATGT GATTTTAGTC 
CATGGAGAAC AGAATGAAAT GGCCAGATTG AAAGCAGCAC TGATTCGAGA ATATGAAGAT 
AACGATGAAG TTCACATAGA GGTTCATAAT CCTCGGAATA CAGAAGCAGT GACCTTAAAC 
TTCAGAGGAG AAAAACTAGC CAAGGTTATG GGATTTTTAG CAGACAAAAA ACCAGAACAA 
GGCCAGCGGG TCTCAGGAAT ACTTGTTAAA AGAAACTTTA ATTATCACAT ACTTTCTCCT 
TGCGACCTGT CCAATTATAC TGACCTGGCC ATGAGCACGG TGAAGCAGAC CCAAGCCATT 
CCATATACTG GTCCCTTTAA TTTGCTCTGT TACCAGCTGC AGAAATTGAC AGGTGATGTG 
GAAGAATTAG AAATTCAAGA AAAACCTGCT CTGAAAGTGT TCAAAAATAT TACTGTAATA 
CAAGAACCAG GCATGGTGGT ATTAGAATGG CTGGCAAACC CTTCTAATGA TATGTATGCA 
GATACAGTAA CAACTGTGAT ATTGGAAGTT CAGTCAAATC CCAAAATAAG AAAAGGTGCA 
GTACAGAAGG TTTCTAAAAA ATTAGAAATG CACGTTTACA GCAAGAGGTT GGAGATCATG 
CTCCAGGACA TATTTGGAGA AGACTGTGTA AGTGTAAAGG ATGACTCTAT TCTTAGCGTC 
ACAGTGGACG GGAAAACTGC CAACCTTAAC TTGGAGACAC GGACTGTAGA ATGTGAAGAG 
GGAAGTGAAG ACGATGAATC CCTCCGAGAA ATGGTGGAGC TGGCTGCACA GAGACTGTAC 
GAGGCCCTGA CGCCAGTTCA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001308763.1
CDS	1486..3429
Translation	MLDCGIHPGLEGMDALPYIDLIDPAEIDLLLISHFHLDHCGALPWFLQKTSFKGRTFMTHATKAIYRWLLSDYVKVSNISADDMLYTETDLEESMDKIETINFHEVKEVAGIKFWCYHAGHVLGAAMFMIEIAGVKLLYTGDFSRQEDRHLMAAEIPNIKPDILIIESTYGTHIHEKREEREARFCNTVHDIVNRGGRGLIPVFALGRAQELLLILDEYWQNHPELHDIPIYYASSLAKKCMAVYQTYVNAMNDKIRKQININNPFVFKHISNLKSMDHFDDIGPSVVMASPGMMQSGLSRELFESWCTDKRNGVIIAGYCVEGTLAKHIMSEPEEITTMSGQKLPLKMSVDYISFSAHTDYQQTSEFIRALKPPHVILVHGEQNEMARLKAALIREYEDNDEVHIEVHNPRNTEAVTLNFRGEKLAKVMGFLADKKPEQGQRVSGILVKRNFNYHILSPCDLSNYTDLAMSTVKQTQAIPYTGPFNLLCYQLQKLTGDVEELEIQEKPALKVFKNITVIQEPGMVVLEWLANPSNDMYADTVTTVILEVQSNPKIRKGAVQKVSKKLEMHVYSKRLEIMLQDIFGEDCVSVKDDSILSVTVDGKTANLNLETRTVECEEGSEDDESLREMVELAAQRLYEALTPVH

Target ORF information:

RefSeq Version	NM_001321834.1
Organism	Homo sapiens(human)
Definition	Homo sapiens cleavage and polyadenylation specific factor 3 (CPSF3), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001321834.1

ORF Insert Sequence:

ATGCTCGACT GTGGGATCCA CCCTGGCCTA GAAGGAATGG ATGCTCTTCC TTATATTGAT 
TTAATTGACC CAGCTGAGAT TGATCTCCTA TTAATTAGTC ATTTCCATTT GGATCACTGT 
GGAGCTCTGC CCTGGTTTCT ACAGAAGACA AGTTTCAAAG GAAGAACATT TATGACTCAT 
GCCACAAAAG CTATTTATAG ATGGCTTCTT TCTGATTATG TCAAAGTTAG TAACATATCA 
GCAGACGACA TGCTGTATAC CGAGACAGAT TTGGAAGAAA GCATGGACAA AATTGAAACT 
ATCAACTTTC ATGAAGTTAA GGAAGTTGCG GGAATCAAGT TTTGGTGTTA CCATGCAGGT 
CACGTCCTAG GAGCCGCCAT GTTCATGATT GAGATCGCAG GCGTGAAGCT TTTGTACACT 
GGTGATTTCT CAAGACAAGA AGATAGGCAC TTAATGGCAG CTGAAATTCC TAATATTAAG 
CCTGATATTC TTATCATTGA ATCTACTTAT GGGACCCATA TCCATGAGAA ACGTGAAGAG 
CGAGAAGCAA GATTCTGTAA CACTGTCCAC GATATTGTAA ACAGAGGAGG CAGGGGTCTC 
ATTCCTGTCT TTGCTCTTGG AAGGGCTCAG GAGCTGCTCT TGATTCTAGA TGAGTACTGG 
CAGAATCACC CAGAACTACA TGACATTCCA ATATACTATG CATCATCTTT GGCCAAGAAG 
TGTATGGCAG TGTACCAGAC ATATGTAAAT GCCATGAATG ACAAAATCCG CAAACAGATC 
AACATCAATA ATCCCTTTGT TTTCAAACAC ATTAGTAACC TCAAGAGCAT GGATCATTTT 
GATGACATTG GTCCCAGTGT TGTAATGGCC TCCCCAGGCA TGATGCAAAG TGGCTTATCC 
AGAGAATTAT TTGAAAGCTG GTGTACTGAT AAGAGGAATG GTGTCATTAT AGCGGGATAC 
TGTGTAGAAG GGACACTTGC CAAGCACATC ATGTCTGAAC CTGAAGAAAT CACTACTATG 
TCTGGACAGA AGTTACCACT GAAAATGTCT GTTGATTACA TTTCTTTCTC AGCTCACACG 
GATTACCAGC AAACCAGTGA ATTTATTCGT GCTTTGAAAC CGCCTCATGT GATTTTAGTC 
CATGGAGAAC AGAATGAAAT GGCCAGATTG AAAGCAGCAC TGATTCGAGA ATATGAAGAT 
AACGATGAAG TTCACATAGA GGTTCATAAT CCTCGGAATA CAGAAGCAGT GACCTTAAAC 
TTCAGAGGAG AAAAACTAGC CAAGGTTATG GGATTTTTAG CAGACAAAAA ACCAGAACAA 
GGCCAGCGGG TCTCAGGAAT ACTTGTTAAA AGAAACTTTA ATTATCACAT ACTTTCTCCT 
TGCGACCTGT CCAATTATAC TGACCTGGCC ATGAGCACGG TGAAGCAGAC CCAAGCCATT 
CCATATACTG GTCCCTTTAA TTTGCTCTGT TACCAGCTGC AGAAATTGAC AGGTGATGTG 
GAAGAATTAG AAATTCAAGA AAAACCTGCT CTGAAAGTGT TCAAAAATAT TACTGTAATA 
CAAGAACCAG GCATGGTGGT ATTAGAATGG CTGGCAAACC CTTCTAATGA TATGTATGCA 
GATACAGTAA CAACTGTGAT ATTGGAAGTT CAGTCAAATC CCAAAATAAG AAAAGGTGCA 
GTACAGAAGG TTTCTAAAAA ATTAGAAATG CACGTTTACA GCAAGAGGTT GGAGATCATG 
CTCCAGGACA TATTTGGAGA AGACTGTGTA AGTGTAAAGG ATGACTCTAT TCTTAGCGTC 
ACAGTGGACG GGAAAACTGC CAACCTTAAC TTGGAGACAC GGACTGTAGA ATGTGAAGAG 
GGAAGTGAAG ACGATGAATC CCTCCGAGAA ATGGTGGAGC TGGCTGCACA GAGACTGTAC 
GAGGCCCTGA CGCCAGTTCA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CPSF3 ( NM_001321835.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001308764.1 Homo sapiens cleavage and polyadenylation specific factor 3 (CPSF3), transcript variant 4, mRNA.

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CloneID	OHu101725
Clone ID Related Accession (Same CDS sequence)	NM_001321835.1
Accession Version	NM_001321835.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1638bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-29
Organism	Homo sapiens(human)
Product	cleavage and polyadenylation specificity factor subunit 3 isoform c
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC420903.1, DA478774.1, BC014106.1 and AA635764.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA2142853 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCCACAAA AGCTATTTAT AGATGGCTTC TTTCTGATTA TGTCAAAGTT AGGTCACGTC 
CTAGGAGCCG CCATGTTCAT GATTGAGATC GCAGGCGTGA AGCTTTTGTA CACTGGTGAT 
TTCTCAAGAC AAGAAGATAG GCACTTAATG GCAGCTGAAA TTCCTAATAT TAAGCCTGAT 
ATTCTTATCA TTGAATCTAC TTATGGGACC CATATCCATG AGAAACGTGA AGAGCGAGAA 
GCAAGATTCT GTAACACTGT CCACGATATT GTAAACAGAG GAGGCAGGGG TCTCATTCCT 
GTCTTTGCTC TTGGAAGGGC TCAGGAGCTG CTCTTGATTC TAGATGAGTA CTGGCAGAAT 
CACCCAGAAC TACATGACAT TCCAATATAC TATGCATCAT CTTTGGCCAA GAAGTGTATG 
GCAGTGTACC AGACATATGT AAATGCCATG AATGACAAAA TCCGCAAACA GATCAACATC 
AATAATCCCT TTGTTTTCAA ACACATTAGT AACCTCAAGA GCATGGATCA TTTTGATGAC 
ATTGGTCCCA GTGTTGTAAT GGCCTCCCCA GGCATGATGC AAAGTGGCTT ATCCAGAGAA 
TTATTTGAAA GCTGGTGTAC TGATAAGAGG AATGGTGTCA TTATAGCGGG ATACTGTGTA 
GAAGGGACAC TTGCCAAGCA CATCATGTCT GAACCTGAAG AAATCACTAC TATGTCTGGA 
CAGAAGTTAC CACTGAAAAT GTCTGTTGAT TACATTTCTT TCTCAGCTCA CACGGATTAC 
CAGCAAACCA GTGAATTTAT TCGTGCTTTG AAACCGCCTC ATGTGATTTT AGTCCATGGA 
GAACAGAATG AAATGGCCAG ATTGAAAGCA GCACTGATTC GAGAATATGA AGATAACGAT 
GAAGTTCACA TAGAGGTTCA TAATCCTCGG AATACAGAAG CAGTGACCTT AAACTTCAGA 
GGAGAAAAAC TAGCCAAGGT TATGGGATTT TTAGCAGACA AAAAACCAGA ACAAGGCCAG 
CGGGTCTCAG GAATACTTGT TAAAAGAAAC TTTAATTATC ACATACTTTC TCCTTGCGAC 
CTGTCCAATT ATACTGACCT GGCCATGAGC ACGGTGAAGC AGACCCAAGC CATTCCATAT 
ACTGGTCCCT TTAATTTGCT CTGTTACCAG CTGCAGAAAT TGACAGGTGA TGTGGAAGAA 
TTAGAAATTC AAGAAAAACC TGCTCTGAAA GTGTTCAAAA ATATTACTGT AATACAAGAA 
CCAGGCATGG TGGTATTAGA ATGGCTGGCA AACCCTTCTA ATGATATGTA TGCAGATACA 
GTAACAACTG TGATATTGGA AGTTCAGTCA AATCCCAAAA TAAGAAAAGG TGCAGTACAG 
AAGGTTTCTA AAAAATTAGA AATGCACGTT TACAGCAAGA GGTTGGAGAT CATGCTCCAG 
GACATATTTG GAGAAGACTG TGTAAGTGTA AAGGATGACT CTATTCTTAG CGTCACAGTG 
GACGGGAAAA CTGCCAACCT TAACTTGGAG ACACGGACTG TAGAATGTGA AGAGGGAAGT 
GAAGACGATG AATCCCTCCG AGAAATGGTG GAGCTGGCTG CACAGAGACT GTACGAGGCC 
CTGACGCCAG TTCACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001308764.1
CDS	527..2164
Translation	MPQKLFIDGFFLIMSKLGHVLGAAMFMIEIAGVKLLYTGDFSRQEDRHLMAAEIPNIKPDILIIESTYGTHIHEKREEREARFCNTVHDIVNRGGRGLIPVFALGRAQELLLILDEYWQNHPELHDIPIYYASSLAKKCMAVYQTYVNAMNDKIRKQININNPFVFKHISNLKSMDHFDDIGPSVVMASPGMMQSGLSRELFESWCTDKRNGVIIAGYCVEGTLAKHIMSEPEEITTMSGQKLPLKMSVDYISFSAHTDYQQTSEFIRALKPPHVILVHGEQNEMARLKAALIREYEDNDEVHIEVHNPRNTEAVTLNFRGEKLAKVMGFLADKKPEQGQRVSGILVKRNFNYHILSPCDLSNYTDLAMSTVKQTQAIPYTGPFNLLCYQLQKLTGDVEELEIQEKPALKVFKNITVIQEPGMVVLEWLANPSNDMYADTVTTVILEVQSNPKIRKGAVQKVSKKLEMHVYSKRLEIMLQDIFGEDCVSVKDDSILSVTVDGKTANLNLETRTVECEEGSEDDESLREMVELAAQRLYEALTPVH

Target ORF information:

RefSeq Version	NM_001321835.1
Organism	Homo sapiens(human)
Definition	Homo sapiens cleavage and polyadenylation specific factor 3 (CPSF3), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001321835.1

ORF Insert Sequence:

ATGCCACAAA AGCTATTTAT AGATGGCTTC TTTCTGATTA TGTCAAAGTT AGGTCACGTC 
CTAGGAGCCG CCATGTTCAT GATTGAGATC GCAGGCGTGA AGCTTTTGTA CACTGGTGAT 
TTCTCAAGAC AAGAAGATAG GCACTTAATG GCAGCTGAAA TTCCTAATAT TAAGCCTGAT 
ATTCTTATCA TTGAATCTAC TTATGGGACC CATATCCATG AGAAACGTGA AGAGCGAGAA 
GCAAGATTCT GTAACACTGT CCACGATATT GTAAACAGAG GAGGCAGGGG TCTCATTCCT 
GTCTTTGCTC TTGGAAGGGC TCAGGAGCTG CTCTTGATTC TAGATGAGTA CTGGCAGAAT 
CACCCAGAAC TACATGACAT TCCAATATAC TATGCATCAT CTTTGGCCAA GAAGTGTATG 
GCAGTGTACC AGACATATGT AAATGCCATG AATGACAAAA TCCGCAAACA GATCAACATC 
AATAATCCCT TTGTTTTCAA ACACATTAGT AACCTCAAGA GCATGGATCA TTTTGATGAC 
ATTGGTCCCA GTGTTGTAAT GGCCTCCCCA GGCATGATGC AAAGTGGCTT ATCCAGAGAA 
TTATTTGAAA GCTGGTGTAC TGATAAGAGG AATGGTGTCA TTATAGCGGG ATACTGTGTA 
GAAGGGACAC TTGCCAAGCA CATCATGTCT GAACCTGAAG AAATCACTAC TATGTCTGGA 
CAGAAGTTAC CACTGAAAAT GTCTGTTGAT TACATTTCTT TCTCAGCTCA CACGGATTAC 
CAGCAAACCA GTGAATTTAT TCGTGCTTTG AAACCGCCTC ATGTGATTTT AGTCCATGGA 
GAACAGAATG AAATGGCCAG ATTGAAAGCA GCACTGATTC GAGAATATGA AGATAACGAT 
GAAGTTCACA TAGAGGTTCA TAATCCTCGG AATACAGAAG CAGTGACCTT AAACTTCAGA 
GGAGAAAAAC TAGCCAAGGT TATGGGATTT TTAGCAGACA AAAAACCAGA ACAAGGCCAG 
CGGGTCTCAG GAATACTTGT TAAAAGAAAC TTTAATTATC ACATACTTTC TCCTTGCGAC 
CTGTCCAATT ATACTGACCT GGCCATGAGC ACGGTGAAGC AGACCCAAGC CATTCCATAT 
ACTGGTCCCT TTAATTTGCT CTGTTACCAG CTGCAGAAAT TGACAGGTGA TGTGGAAGAA 
TTAGAAATTC AAGAAAAACC TGCTCTGAAA GTGTTCAAAA ATATTACTGT AATACAAGAA 
CCAGGCATGG TGGTATTAGA ATGGCTGGCA AACCCTTCTA ATGATATGTA TGCAGATACA 
GTAACAACTG TGATATTGGA AGTTCAGTCA AATCCCAAAA TAAGAAAAGG TGCAGTACAG 
AAGGTTTCTA AAAAATTAGA AATGCACGTT TACAGCAAGA GGTTGGAGAT CATGCTCCAG 
GACATATTTG GAGAAGACTG TGTAAGTGTA AAGGATGACT CTATTCTTAG CGTCACAGTG 
GACGGGAAAA CTGCCAACCT TAACTTGGAG ACACGGACTG TAGAATGTGA AGAGGGAAGT 
GAAGACGATG AATCCCTCCG AGAAATGGTG GAGCTGGCTG CACAGAGACT GTACGAGGCC 
CTGACGCCAG TTCACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A complex containing the CPSF73 endonuclease and other polyadenylation factors associates with U7 snRNP and is recruited to histone pre-mRNA for 3'-end processing.
Molecular and cellular biology33(1)28-37(2013 Jan)
Yang XC,Sabath I,D?bski J,Kaus-Drobek M,Dadlez M,Marzluff WF,Dominski Z

The poly A polymerase Star-PAP controls 3'-end cleavage by promoting CPSF interaction and specificity toward the pre-mRNA.
The EMBO journal29(24)4132-45(2010 Dec)
Laishram RS,Anderson RA

Studies of the 5' exonuclease and endonuclease activities of CPSF-73 in histone pre-mRNA processing.
Molecular and cellular biology29(1)31-42(2009 Jan)
Yang XC,Sullivan KD,Marzluff WF,Dominski Z

The tumor suppressor Cdc73 functionally associates with CPSF and CstF 3' mRNA processing factors.
Proceedings of the National Academy of Sciences of the United States of America106(3)755-60(2009 Jan)
Rozenblatt-Rosen O,Nagaike T,Francis JM,Kaneko S,Glatt KA,Hughes CM,LaFramboise T,Manley JL,Meyerson M

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CPSF3 cDNA ORF clone, Homo sapiens(human)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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