| Gene Symbol | TCF7L2 |
| Entrez Gene ID | 6934 |
| Full Name | transcription factor 7 like 2 |
| Synonyms | TCF-4,TCF4 |
| General protein information |
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| Gene Type | protein-coding |
| Organism | Homo sapiens(human) |
| Genome | |
| Summary | This gene encodes a high mobility group (HMG) box-containing transcription factor that plays a key role in the Wnt signaling pathway. The protein has been implicated in blood glucose homeostasis. Genetic variants of this gene are associated with increased risk of type 2 diabetes. Several transcript variants encoding multiple different isoforms have been found for this gene.[provided by RefSeq, Oct 2010]. |
| Disorder MIM: | |
| Disorder Html: | {Diabetes mellitus, type 2, susceptibility to}, 125853 (3) |
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