TEAD4 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	TEAD4
Entrez Gene ID	7004
Full Name	TEA domain transcription factor 4
Synonyms	EFTR-2,RTEF1,TCF13L1,TEF-3,TEF3,TEFR-1,hRTEF-1B
General protein information	Preferred Names TEA domain transcription factor 4 Names transcriptional enhancer factor TEF-3 TEA domain family member 4 related transcription enhancer factor 1B transcription factor 13-like 1 transcription factor RTEF-1 transcriptional enhancer factor 1-related transcriptional enhancer factor 3
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 12 Map Location: 12p13.33
Summary	This gene product is a member of the transcriptional enhancer factor (TEF) family of transcription factors, which contain the TEA/ATTS DNA-binding domain. It is preferentially expressed in the skeletal muscle, and binds to the M-CAT regulatory element found in promoters of muscle-specific genes to direct their gene expression. Alternatively spliced transcripts encoding distinct isoforms, some of which are translated through the use of a non-AUG (UUG) initiation codon, have been described for this gene. [provided by RefSeq, Jul 2008].
Disorder MIM:	601714

mRNA and Protein(s)

mRNA	Protein	Name
NM_003213.3	NP_003204.2	transcriptional enhancer factor TEF-3 isoform 1
NM_201441.2	NP_958849.1	transcriptional enhancer factor TEF-3 isoform 2
NM_201443.2	NP_958851.1	transcriptional enhancer factor TEF-3 isoform 3
NM_201443.3	NP_958851.1	transcriptional enhancer factor TEF-3 isoform 3
NM_003213.4	NP_003204.2	transcriptional enhancer factor TEF-3 isoform 1
NM_201441.3	NP_958849.1	transcriptional enhancer factor TEF-3 isoform 2

Pathways from BioSystems

Homologies

	LOC721772	XP_001117976.2
Canis lupus familiaris (dog)	TEAD4	XP_005637347.1
Bos taurus (cattle)	TEAD4	XP_002687928.2
Homo sapiens (human)	TEAD4	NP_003204.2
Pan troglodytes (chimpanzee)	TEAD4	XP_508934.3
Rattus norvegicus (Norway rat)	Tead4	XP_006237486.1
Gallus gallus (chicken)	TEAD4	NP_001001339.1
Mus musculus (house mouse)	Tead4	NP_035697.3
Xenopus tropicalis (tropical clawed frog)	tead4	XP_002938560.2

Gene Ontology
Bibliography

Related articles in PubMed

Effect of the acylation of TEAD4 on its interaction with co-activators YAP and TAZ.
Mesrouze Y, Meyerhofer M, Bokhovchuk F, Fontana P, Zimmermann C, Martin T, Delaunay C, Izaac A, Kallen J, Schmelzle T, Erdmann D, Ch?ne P
Protein science : a publication of the Protein Society26(12)2399-2409(2017 Dec)

TEAD1/4 exerts oncogenic role and is negatively regulated by miR-4269 in gastric tumorigenesis.
Zhou Y, Huang T, Zhang J, Wong CC, Zhang B, Dong Y, Wu F, Tong JHM, Wu WKK, Cheng ASL, Yu J, Kang W, To KF
Oncogene36(47)6518-6530(2017 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Studied the effect of TEAD4 acylation on its interaction with YAP and TAZ; found YAP and TAZ bind in a similar manner to both acylated and non-acylated TEAD4. Also found TEAD4 acylation significantly enhances its stability.
Title: Effect of the acylation of TEAD4 on its interaction with co-activators YAP and TAZ.

TEAD1 and TEAD4 are oncogenic factors, whose aberrant activation are, in part, mediated by the silence of miR-377-3p, miR-1343-3p and miR-4269.
Title: TEAD1/4 exerts oncogenic role and is negatively regulated by miR-4269 in gastric tumorigenesis.

our work provides a structural basis for understanding the regulatory mechanism of TEAD4-mediated gene transcription
Title: DNA-binding mechanism of the Hippo pathway transcription factor TEAD4.

Osmotic stress promotes TEAD4 cytoplasmic translocation via p38 MAPK in a Hippo-independent manner. Stress-induced TEAD inhibition predominates YAP-activating signals and selectively suppresses YAP-driven cancer cell growth.
Title: Regulation of Hippo pathway transcription factor TEAD by p38 MAPK-induced cytoplasmic translocation.

Combining single site-directed mutagenesis and double mutant analyses, the authors conduct a detailed analysis on the role of several residues located at the YAP:TEAD interface. The results provide quantitative understanding of the interactions taking place at the YAP:TEAD interface and give insights into the formation of the YAP:TEAD complex and more particularly on the interaction between TEAD and the ohm-loop found ...
Title: Dissection of the interaction between the intrinsically disordered YAP protein and the transcription factor TEAD.

The following TEAD4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TEAD4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu23471	NM_003213.4 Latest version!	Homo sapiens TEA domain transcription factor 4 (TEAD4), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu23773	NM_201443.3 Latest version!	Homo sapiens TEA domain transcription factor 4 (TEAD4), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$154.50-$216.30 $309.00
OHu23981	NM_201441.3 Latest version!	Homo sapiens TEA domain transcription factor 4 (TEAD4), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$230.30 $329.00
View Old Accession Versions >>
OHu23773	NM_201443.2	Homo sapiens TEA domain transcription factor 4 (TEAD4), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$154.50-$216.30 $309.00
OHu23471	NM_003213.3	Homo sapiens TEA domain transcription factor 4 (TEAD4), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu23981	NM_201441.2	Homo sapiens TEA domain transcription factor 4 (TEAD4), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$230.30 $329.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

TEAD4 ( NM_003213.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_003204.2 Homo sapiens TEA domain transcription factor 4 (TEAD4), transcript variant 1, mRNA.

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CloneID	OHu23471
Clone ID Related Accession (Same CDS sequence)	NM_003213.3 , NM_003213.4
Accession Version	NM_003213.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1305bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-17
Organism	Homo sapiens(human)
Product	transcriptional enhancer factor TEF-3 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA210894.1, BC015497.1 and U63824.1. This sequence is a reference standard in the RefSeqGene project. On Jul 9, 2010 this sequence version replaced NM_003213.2. Transcript Variant: This variant (1) encodes the longest isoform (1), and initiates translation from a non-AUG (UUG) codon. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: U63824.1, BC015497.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA2142363 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## non-AUG initiation codon :: PMID: 8921372 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

TTGGAGGGCA CGGCCGGCAC CATTACCTCC AACGAGTGGA GCTCTCCCAC CTCCCCTGAG 
GGGAGCACCG CCTCTGGGGG CAGTCAGGCA CTGGACAAGC CCATCGACAA TGACGCAGAG 
GGCGTGTGGA GCCCGGATAT TGAGCAGAGT TTCCAGGAGG CCCTCGCCAT CTACCCGCCC 
TGTGGCAGGC GCAAAATCAT CCTGTCGGAC GAGGGCAAGA TGTATGGTCG GAACGAGCTG 
ATTGCCCGCT ACATCAAGCT CCGGACAGGG AAGACCCGCA CCAGGAAGCA GGTCTCCAGC 
CACATCCAGG TGCTGGCTCG TCGCAAAGCT CGCGAGATCC AGGCCAAGCT AAAGGACCAG 
GCAGCTAAGG ACAAGGCCCT GCAGAGCATG GCTGCCATGT CGTCTGCACA GATCATCTCC 
GCCACGGCCT TCCACAGTAG CATGGCCCTC GCCCGGGGCC CCGGCCGCCC AGCAGTCTCA 
GGGTTTTGGC AAGGAGCTTT GCCAGGCCAA GCCGGAACGT CCCATGATGT GAAGCCTTTC 
TCTCAGCAAA CCTATGCTGT CCAGCCTCCG CTGCCTCTGC CAGGGTTTGA GTCTCCTGCA 
GGGCCCGCCC CATCGCCCTC TGCGCCCCCG GCACCCCCAT GGCAGGGCCG CAGCGTGGCC 
AGCTCCAAGC TCTGGATGTT GGAGTTCTCT GCCTTCCTGG AGCAGCAGCA GGACCCGGAC 
ACGTACAACA AGCACCTGTT CGTGCACATT GGCCAGTCCA GCCCAAGCTA CAGCGACCCC 
TACCTCGAAG CCGTGGACAT CCGCCAAATC TATGACAAAT TCCCGGAGAA AAAGGGTGGA 
CTCAAGGATC TCTTCGAACG GGGACCCTCC AATGCCTTTT TTCTTGTGAA GTTCTGGGCA 
GACCTCAACA CCAACATCGA GGATGAAGGC AGCTCCTTCT ATGGGGTCTC CAGCCAGTAT 
GAGAGCCCCG AGAACATGAT CATCACCTGC TCCACGAAGG TCTGCTCTTT CGGCAAGCAG 
GTGGTGGAGA AAGTTGAGAC AGAGTATGCT CGCTATGAGA ATGGACACTA CTCTTACCGC 
ATCCACCGGT CCCCGCTCTG TGAGTACATG ATCAACTTCA TCCACAAGCT CAAGCACCTC 
CCTGAGAAGT ACATGATGAA CAGCGTGCTG GAGAACTTCA CCATCCTGCA GGTGGTCACC 
AACAGAGACA CACAGGAGAC CTTGCTGTGC ATTGCCTATG TCTTTGAGGT GTCAGCCAGT 
GAGCACGGGG CTCAGCACCA CATCTACAGG CTGGTGAAAG AATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_003204.2
CDS	293..1597
Translation	LEGTAGTITSNEWSSPTSPEGSTASGGSQALDKPIDNDAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKAREIQAKLKDQAAKDKALQSMAAMSSAQIISATAFHSSMALARGPGRPAVSGFWQGALPGQAGTSHDVKPFSQQTYAVQPPLPLPGFESPAGPAPSPSAPPAPPWQGRSVASSKLWMLEFSAFLEQQQDPDTYNKHLFVHIGQSSPSYSDPYLEAVDIRQIYDKFPEKKGGLKDLFERGPSNAFFLVKFWADLNTNIEDEGSSFYGVSSQYESPENMIITCSTKVCSFGKQVVEKVETEYARYENGHYSYRIHRSPLCEYMINFIHKLKHLPEKYMMNSVLENFTILQVVTNRDTQETLLCIAYVFEVSASEHGAQHHIYRLVKE

Target ORF information:

RefSeq Version	NM_003213.3
Organism	Homo sapiens(human)
Definition	Homo sapiens TEA domain transcription factor 4 (TEAD4), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_003213.3

ORF Insert Sequence:

TTGGAGGGCA CGGCCGGCAC CATTACCTCC AACGAGTGGA GCTCTCCCAC CTCCCCTGAG 
GGGAGCACCG CCTCTGGGGG CAGTCAGGCA CTGGACAAGC CCATCGACAA TGACGCAGAG 
GGCGTGTGGA GCCCGGATAT TGAGCAGAGT TTCCAGGAGG CCCTCGCCAT CTACCCGCCC 
TGTGGCAGGC GCAAAATCAT CCTGTCGGAC GAGGGCAAGA TGTATGGTCG GAACGAGCTG 
ATTGCCCGCT ACATCAAGCT CCGGACAGGG AAGACCCGCA CCAGGAAGCA GGTCTCCAGC 
CACATCCAGG TGCTGGCTCG TCGCAAAGCT CGCGAGATCC AGGCCAAGCT AAAGGACCAG 
GCAGCTAAGG ACAAGGCCCT GCAGAGCATG GCTGCCATGT CGTCTGCACA GATCATCTCC 
GCCACGGCCT TCCACAGTAG CATGGCCCTC GCCCGGGGCC CCGGCCGCCC AGCAGTCTCA 
GGGTTTTGGC AAGGAGCTTT GCCAGGCCAA GCCGGAACGT CCCATGATGT GAAGCCTTTC 
TCTCAGCAAA CCTATGCTGT CCAGCCTCCG CTGCCTCTGC CAGGGTTTGA GTCTCCTGCA 
GGGCCCGCCC CATCGCCCTC TGCGCCCCCG GCACCCCCAT GGCAGGGCCG CAGCGTGGCC 
AGCTCCAAGC TCTGGATGTT GGAGTTCTCT GCCTTCCTGG AGCAGCAGCA GGACCCGGAC 
ACGTACAACA AGCACCTGTT CGTGCACATT GGCCAGTCCA GCCCAAGCTA CAGCGACCCC 
TACCTCGAAG CCGTGGACAT CCGCCAAATC TATGACAAAT TCCCGGAGAA AAAGGGTGGA 
CTCAAGGATC TCTTCGAACG GGGACCCTCC AATGCCTTTT TTCTTGTGAA GTTCTGGGCA 
GACCTCAACA CCAACATCGA GGATGAAGGC AGCTCCTTCT ATGGGGTCTC CAGCCAGTAT 
GAGAGCCCCG AGAACATGAT CATCACCTGC TCCACGAAGG TCTGCTCTTT CGGCAAGCAG 
GTGGTGGAGA AAGTTGAGAC AGAGTATGCT CGCTATGAGA ATGGACACTA CTCTTACCGC 
ATCCACCGGT CCCCGCTCTG TGAGTACATG ATCAACTTCA TCCACAAGCT CAAGCACCTC 
CCTGAGAAGT ACATGATGAA CAGCGTGCTG GAGAACTTCA CCATCCTGCA GGTGGTCACC 
AACAGAGACA CACAGGAGAC CTTGCTGTGC ATTGCCTATG TCTTTGAGGT GTCAGCCAGT 
GAGCACGGGG CTCAGCACCA CATCTACAGG CTGGTGAAAG AATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TEAD4 ( NM_003213.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_003204.2 Homo sapiens TEA domain transcription factor 4 (TEAD4), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu23471
Clone ID Related Accession (Same CDS sequence)	NM_003213.3 , NM_003213.4
Accession Version	NM_003213.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1305bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-15
Organism	Homo sapiens(human)
Product	transcriptional enhancer factor TEF-3 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA210894.1, BC015497.1 and U63824.1. This sequence is a reference standard in the RefSeqGene project. On Nov 23, 2018 this sequence version replaced NM_003213.3. Transcript Variant: This variant (1) encodes the longest isoform (1), and initiates translation from a non-AUG (UUG) codon. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: U63824.1, BC015497.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA2142363 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## non-AUG initiation codon :: PMID: 8921372 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

TTGGAGGGCA CGGCCGGCAC CATTACCTCC AACGAGTGGA GCTCTCCCAC CTCCCCTGAG 
GGGAGCACCG CCTCTGGGGG CAGTCAGGCA CTGGACAAGC CCATCGACAA TGACGCAGAG 
GGCGTGTGGA GCCCGGATAT TGAGCAGAGT TTCCAGGAGG CCCTCGCCAT CTACCCGCCC 
TGTGGCAGGC GCAAAATCAT CCTGTCGGAC GAGGGCAAGA TGTATGGTCG GAACGAGCTG 
ATTGCCCGCT ACATCAAGCT CCGGACAGGG AAGACCCGCA CCAGGAAGCA GGTCTCCAGC 
CACATCCAGG TGCTGGCTCG TCGCAAAGCT CGCGAGATCC AGGCCAAGCT AAAGGACCAG 
GCAGCTAAGG ACAAGGCCCT GCAGAGCATG GCTGCCATGT CGTCTGCACA GATCATCTCC 
GCCACGGCCT TCCACAGTAG CATGGCCCTC GCCCGGGGCC CCGGCCGCCC AGCAGTCTCA 
GGGTTTTGGC AAGGAGCTTT GCCAGGCCAA GCCGGAACGT CCCATGATGT GAAGCCTTTC 
TCTCAGCAAA CCTATGCTGT CCAGCCTCCG CTGCCTCTGC CAGGGTTTGA GTCTCCTGCA 
GGGCCCGCCC CATCGCCCTC TGCGCCCCCG GCACCCCCAT GGCAGGGCCG CAGCGTGGCC 
AGCTCCAAGC TCTGGATGTT GGAGTTCTCT GCCTTCCTGG AGCAGCAGCA GGACCCGGAC 
ACGTACAACA AGCACCTGTT CGTGCACATT GGCCAGTCCA GCCCAAGCTA CAGCGACCCC 
TACCTCGAAG CCGTGGACAT CCGCCAAATC TATGACAAAT TCCCGGAGAA AAAGGGTGGA 
CTCAAGGATC TCTTCGAACG GGGACCCTCC AATGCCTTTT TTCTTGTGAA GTTCTGGGCA 
GACCTCAACA CCAACATCGA GGATGAAGGC AGCTCCTTCT ATGGGGTCTC CAGCCAGTAT 
GAGAGCCCCG AGAACATGAT CATCACCTGC TCCACGAAGG TCTGCTCTTT CGGCAAGCAG 
GTGGTGGAGA AAGTTGAGAC AGAGTATGCT CGCTATGAGA ATGGACACTA CTCTTACCGC 
ATCCACCGGT CCCCGCTCTG TGAGTACATG ATCAACTTCA TCCACAAGCT CAAGCACCTC 
CCTGAGAAGT ACATGATGAA CAGCGTGCTG GAGAACTTCA CCATCCTGCA GGTGGTCACC 
AACAGAGACA CACAGGAGAC CTTGCTGTGC ATTGCCTATG TCTTTGAGGT GTCAGCCAGT 
GAGCACGGGG CTCAGCACCA CATCTACAGG CTGGTGAAAG AATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_003204.2
CDS	208..1512
Translation	LEGTAGTITSNEWSSPTSPEGSTASGGSQALDKPIDNDAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKAREIQAKLKDQAAKDKALQSMAAMSSAQIISATAFHSSMALARGPGRPAVSGFWQGALPGQAGTSHDVKPFSQQTYAVQPPLPLPGFESPAGPAPSPSAPPAPPWQGRSVASSKLWMLEFSAFLEQQQDPDTYNKHLFVHIGQSSPSYSDPYLEAVDIRQIYDKFPEKKGGLKDLFERGPSNAFFLVKFWADLNTNIEDEGSSFYGVSSQYESPENMIITCSTKVCSFGKQVVEKVETEYARYENGHYSYRIHRSPLCEYMINFIHKLKHLPEKYMMNSVLENFTILQVVTNRDTQETLLCIAYVFEVSASEHGAQHHIYRLVKE

Target ORF information:

RefSeq Version	NM_003213.4
Organism	Homo sapiens(human)
Definition	Homo sapiens TEA domain transcription factor 4 (TEAD4), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_003213.4

ORF Insert Sequence:

TTGGAGGGCA CGGCCGGCAC CATTACCTCC AACGAGTGGA GCTCTCCCAC CTCCCCTGAG 
GGGAGCACCG CCTCTGGGGG CAGTCAGGCA CTGGACAAGC CCATCGACAA TGACGCAGAG 
GGCGTGTGGA GCCCGGATAT TGAGCAGAGT TTCCAGGAGG CCCTCGCCAT CTACCCGCCC 
TGTGGCAGGC GCAAAATCAT CCTGTCGGAC GAGGGCAAGA TGTATGGTCG GAACGAGCTG 
ATTGCCCGCT ACATCAAGCT CCGGACAGGG AAGACCCGCA CCAGGAAGCA GGTCTCCAGC 
CACATCCAGG TGCTGGCTCG TCGCAAAGCT CGCGAGATCC AGGCCAAGCT AAAGGACCAG 
GCAGCTAAGG ACAAGGCCCT GCAGAGCATG GCTGCCATGT CGTCTGCACA GATCATCTCC 
GCCACGGCCT TCCACAGTAG CATGGCCCTC GCCCGGGGCC CCGGCCGCCC AGCAGTCTCA 
GGGTTTTGGC AAGGAGCTTT GCCAGGCCAA GCCGGAACGT CCCATGATGT GAAGCCTTTC 
TCTCAGCAAA CCTATGCTGT CCAGCCTCCG CTGCCTCTGC CAGGGTTTGA GTCTCCTGCA 
GGGCCCGCCC CATCGCCCTC TGCGCCCCCG GCACCCCCAT GGCAGGGCCG CAGCGTGGCC 
AGCTCCAAGC TCTGGATGTT GGAGTTCTCT GCCTTCCTGG AGCAGCAGCA GGACCCGGAC 
ACGTACAACA AGCACCTGTT CGTGCACATT GGCCAGTCCA GCCCAAGCTA CAGCGACCCC 
TACCTCGAAG CCGTGGACAT CCGCCAAATC TATGACAAAT TCCCGGAGAA AAAGGGTGGA 
CTCAAGGATC TCTTCGAACG GGGACCCTCC AATGCCTTTT TTCTTGTGAA GTTCTGGGCA 
GACCTCAACA CCAACATCGA GGATGAAGGC AGCTCCTTCT ATGGGGTCTC CAGCCAGTAT 
GAGAGCCCCG AGAACATGAT CATCACCTGC TCCACGAAGG TCTGCTCTTT CGGCAAGCAG 
GTGGTGGAGA AAGTTGAGAC AGAGTATGCT CGCTATGAGA ATGGACACTA CTCTTACCGC 
ATCCACCGGT CCCCGCTCTG TGAGTACATG ATCAACTTCA TCCACAAGCT CAAGCACCTC 
CCTGAGAAGT ACATGATGAA CAGCGTGCTG GAGAACTTCA CCATCCTGCA GGTGGTCACC 
AACAGAGACA CACAGGAGAC CTTGCTGTGC ATTGCCTATG TCTTTGAGGT GTCAGCCAGT 
GAGCACGGGG CTCAGCACCA CATCTACAGG CTGGTGAAAG AATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TEAD4 ( NM_201443.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_958851.1 Homo sapiens TEA domain transcription factor 4 (TEAD4), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu23773
Clone ID Related Accession (Same CDS sequence)	NM_201443.2 , NM_201443.3
Accession Version	NM_201443.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 918bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-21
Organism	Homo sapiens(human)
Product	transcriptional enhancer factor TEF-3 isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA886817.1, BX640921.1 and U63824.1. On Jul 9, 2010 this sequence version replaced NM_201443.1. Transcript Variant: This variant (3) lacks the exon containing the non-AUG (UUG) translation initiation codon compared to variant 1. It uses an in-frame, downstream AUG, resulting in an isoform (3) with a shorter N-terminus compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BX640921.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2142853, SAMEA2146236 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTGCCA TGTCGTCTGC ACAGATCATC TCCGCCACGG CCTTCCACAG TAGCATGGCC 
CTCGCCCGGG GCCCCGGCCG CCCAGCAGTC TCAGGGTTTT GGCAAGGAGC TTTGCCAGGC 
CAAGCCGGAA CGTCCCATGA TGTGAAGCCT TTCTCTCAGC AAACCTATGC TGTCCAGCCT 
CCGCTGCCTC TGCCAGGGTT TGAGTCTCCT GCAGGGCCCG CCCCATCGCC CTCTGCGCCC 
CCGGCACCCC CATGGCAGGG CCGCAGCGTG GCCAGCTCCA AGCTCTGGAT GTTGGAGTTC 
TCTGCCTTCC TGGAGCAGCA GCAGGACCCG GACACGTACA ACAAGCACCT GTTCGTGCAC 
ATTGGCCAGT CCAGCCCAAG CTACAGCGAC CCCTACCTCG AAGCCGTGGA CATCCGCCAA 
ATCTATGACA AATTCCCGGA GAAAAAGGGT GGACTCAAGG ATCTCTTCGA ACGGGGACCC 
TCCAATGCCT TTTTTCTTGT GAAGTTCTGG GCAGACCTCA ACACCAACAT CGAGGATGAA 
GGCAGCTCCT TCTATGGGGT CTCCAGCCAG TATGAGAGCC CCGAGAACAT GATCATCACC 
TGCTCCACGA AGGTCTGCTC TTTCGGCAAG CAGGTGGTGG AGAAAGTTGA GACAGAGTAT 
GCTCGCTATG AGAATGGACA CTACTCTTAC CGCATCCACC GGTCCCCGCT CTGTGAGTAC 
ATGATCAACT TCATCCACAA GCTCAAGCAC CTCCCTGAGA AGTACATGAT GAACAGCGTG 
CTGGAGAACT TCACCATCCT GCAGGTGGTC ACCAACAGAG ACACACAGGA GACCTTGCTG 
TGCATTGCCT ATGTCTTTGA GGTGTCAGCC AGTGAGCACG GGGCTCAGCA CCACATCTAC 
AGGCTGGTGA AAGAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_958851.1
CDS	621..1538
Translation	MAAMSSAQIISATAFHSSMALARGPGRPAVSGFWQGALPGQAGTSHDVKPFSQQTYAVQPPLPLPGFESPAGPAPSPSAPPAPPWQGRSVASSKLWMLEFSAFLEQQQDPDTYNKHLFVHIGQSSPSYSDPYLEAVDIRQIYDKFPEKKGGLKDLFERGPSNAFFLVKFWADLNTNIEDEGSSFYGVSSQYESPENMIITCSTKVCSFGKQVVEKVETEYARYENGHYSYRIHRSPLCEYMINFIHKLKHLPEKYMMNSVLENFTILQVVTNRDTQETLLCIAYVFEVSASEHGAQHHIYRLVKE

Target ORF information:

RefSeq Version	NM_201443.2
Organism	Homo sapiens(human)
Definition	Homo sapiens TEA domain transcription factor 4 (TEAD4), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_201443.2

ORF Insert Sequence:

ATGGCTGCCA TGTCGTCTGC ACAGATCATC TCCGCCACGG CCTTCCACAG TAGCATGGCC 
CTCGCCCGGG GCCCCGGCCG CCCAGCAGTC TCAGGGTTTT GGCAAGGAGC TTTGCCAGGC 
CAAGCCGGAA CGTCCCATGA TGTGAAGCCT TTCTCTCAGC AAACCTATGC TGTCCAGCCT 
CCGCTGCCTC TGCCAGGGTT TGAGTCTCCT GCAGGGCCCG CCCCATCGCC CTCTGCGCCC 
CCGGCACCCC CATGGCAGGG CCGCAGCGTG GCCAGCTCCA AGCTCTGGAT GTTGGAGTTC 
TCTGCCTTCC TGGAGCAGCA GCAGGACCCG GACACGTACA ACAAGCACCT GTTCGTGCAC 
ATTGGCCAGT CCAGCCCAAG CTACAGCGAC CCCTACCTCG AAGCCGTGGA CATCCGCCAA 
ATCTATGACA AATTCCCGGA GAAAAAGGGT GGACTCAAGG ATCTCTTCGA ACGGGGACCC 
TCCAATGCCT TTTTTCTTGT GAAGTTCTGG GCAGACCTCA ACACCAACAT CGAGGATGAA 
GGCAGCTCCT TCTATGGGGT CTCCAGCCAG TATGAGAGCC CCGAGAACAT GATCATCACC 
TGCTCCACGA AGGTCTGCTC TTTCGGCAAG CAGGTGGTGG AGAAAGTTGA GACAGAGTAT 
GCTCGCTATG AGAATGGACA CTACTCTTAC CGCATCCACC GGTCCCCGCT CTGTGAGTAC 
ATGATCAACT TCATCCACAA GCTCAAGCAC CTCCCTGAGA AGTACATGAT GAACAGCGTG 
CTGGAGAACT TCACCATCCT GCAGGTGGTC ACCAACAGAG ACACACAGGA GACCTTGCTG 
TGCATTGCCT ATGTCTTTGA GGTGTCAGCC AGTGAGCACG GGGCTCAGCA CCACATCTAC 
AGGCTGGTGA AAGAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TEAD4 ( NM_201443.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_958851.1 Homo sapiens TEA domain transcription factor 4 (TEAD4), transcript variant 3, mRNA.

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CloneID	OHu23773
Clone ID Related Accession (Same CDS sequence)	NM_201443.2 , NM_201443.3
Accession Version	NM_201443.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 918bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-15
Organism	Homo sapiens(human)
Product	transcriptional enhancer factor TEF-3 isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA886817.1, BX640921.1 and U63824.1. On Jun 2, 2019 this sequence version replaced NM_201443.2. Transcript Variant: This variant (3) lacks the exon containing the non-AUG (UUG) translation initiation codon compared to variant 1. It uses an in-frame, downstream AUG, resulting in an isoform (3) with a shorter N-terminus compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BX640921.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2142853, SAMEA2146236 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTGCCA TGTCGTCTGC ACAGATCATC TCCGCCACGG CCTTCCACAG TAGCATGGCC 
CTCGCCCGGG GCCCCGGCCG CCCAGCAGTC TCAGGGTTTT GGCAAGGAGC TTTGCCAGGC 
CAAGCCGGAA CGTCCCATGA TGTGAAGCCT TTCTCTCAGC AAACCTATGC TGTCCAGCCT 
CCGCTGCCTC TGCCAGGGTT TGAGTCTCCT GCAGGGCCCG CCCCATCGCC CTCTGCGCCC 
CCGGCACCCC CATGGCAGGG CCGCAGCGTG GCCAGCTCCA AGCTCTGGAT GTTGGAGTTC 
TCTGCCTTCC TGGAGCAGCA GCAGGACCCG GACACGTACA ACAAGCACCT GTTCGTGCAC 
ATTGGCCAGT CCAGCCCAAG CTACAGCGAC CCCTACCTCG AAGCCGTGGA CATCCGCCAA 
ATCTATGACA AATTCCCGGA GAAAAAGGGT GGACTCAAGG ATCTCTTCGA ACGGGGACCC 
TCCAATGCCT TTTTTCTTGT GAAGTTCTGG GCAGACCTCA ACACCAACAT CGAGGATGAA 
GGCAGCTCCT TCTATGGGGT CTCCAGCCAG TATGAGAGCC CCGAGAACAT GATCATCACC 
TGCTCCACGA AGGTCTGCTC TTTCGGCAAG CAGGTGGTGG AGAAAGTTGA GACAGAGTAT 
GCTCGCTATG AGAATGGACA CTACTCTTAC CGCATCCACC GGTCCCCGCT CTGTGAGTAC 
ATGATCAACT TCATCCACAA GCTCAAGCAC CTCCCTGAGA AGTACATGAT GAACAGCGTG 
CTGGAGAACT TCACCATCCT GCAGGTGGTC ACCAACAGAG ACACACAGGA GACCTTGCTG 
TGCATTGCCT ATGTCTTTGA GGTGTCAGCC AGTGAGCACG GGGCTCAGCA CCACATCTAC 
AGGCTGGTGA AAGAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_958851.1
CDS	268..1185
Translation	MAAMSSAQIISATAFHSSMALARGPGRPAVSGFWQGALPGQAGTSHDVKPFSQQTYAVQPPLPLPGFESPAGPAPSPSAPPAPPWQGRSVASSKLWMLEFSAFLEQQQDPDTYNKHLFVHIGQSSPSYSDPYLEAVDIRQIYDKFPEKKGGLKDLFERGPSNAFFLVKFWADLNTNIEDEGSSFYGVSSQYESPENMIITCSTKVCSFGKQVVEKVETEYARYENGHYSYRIHRSPLCEYMINFIHKLKHLPEKYMMNSVLENFTILQVVTNRDTQETLLCIAYVFEVSASEHGAQHHIYRLVKE

Target ORF information:

RefSeq Version	NM_201443.3
Organism	Homo sapiens(human)
Definition	Homo sapiens TEA domain transcription factor 4 (TEAD4), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_201443.3

ORF Insert Sequence:

ATGGCTGCCA TGTCGTCTGC ACAGATCATC TCCGCCACGG CCTTCCACAG TAGCATGGCC 
CTCGCCCGGG GCCCCGGCCG CCCAGCAGTC TCAGGGTTTT GGCAAGGAGC TTTGCCAGGC 
CAAGCCGGAA CGTCCCATGA TGTGAAGCCT TTCTCTCAGC AAACCTATGC TGTCCAGCCT 
CCGCTGCCTC TGCCAGGGTT TGAGTCTCCT GCAGGGCCCG CCCCATCGCC CTCTGCGCCC 
CCGGCACCCC CATGGCAGGG CCGCAGCGTG GCCAGCTCCA AGCTCTGGAT GTTGGAGTTC 
TCTGCCTTCC TGGAGCAGCA GCAGGACCCG GACACGTACA ACAAGCACCT GTTCGTGCAC 
ATTGGCCAGT CCAGCCCAAG CTACAGCGAC CCCTACCTCG AAGCCGTGGA CATCCGCCAA 
ATCTATGACA AATTCCCGGA GAAAAAGGGT GGACTCAAGG ATCTCTTCGA ACGGGGACCC 
TCCAATGCCT TTTTTCTTGT GAAGTTCTGG GCAGACCTCA ACACCAACAT CGAGGATGAA 
GGCAGCTCCT TCTATGGGGT CTCCAGCCAG TATGAGAGCC CCGAGAACAT GATCATCACC 
TGCTCCACGA AGGTCTGCTC TTTCGGCAAG CAGGTGGTGG AGAAAGTTGA GACAGAGTAT 
GCTCGCTATG AGAATGGACA CTACTCTTAC CGCATCCACC GGTCCCCGCT CTGTGAGTAC 
ATGATCAACT TCATCCACAA GCTCAAGCAC CTCCCTGAGA AGTACATGAT GAACAGCGTG 
CTGGAGAACT TCACCATCCT GCAGGTGGTC ACCAACAGAG ACACACAGGA GACCTTGCTG 
TGCATTGCCT ATGTCTTTGA GGTGTCAGCC AGTGAGCACG GGGCTCAGCA CCACATCTAC 
AGGCTGGTGA AAGAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TEAD4 ( NM_201441.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_958849.1 Homo sapiens TEA domain transcription factor 4 (TEAD4), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu23981
Clone ID Related Accession (Same CDS sequence)	NM_201441.2 , NM_201441.3
Accession Version	NM_201441.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1176bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-22
Organism	Homo sapiens(human)
Product	transcriptional enhancer factor TEF-3 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA210894.1, AY101179.1, BM555991.1 and U63824.1. On Jul 9, 2010 this sequence version replaced NM_201441.1. Transcript Variant: This variant (2) lacks an in-frame coding exon compared to variant 1, resulting in an isoform (2) that is missing an internal segment compared to isoform 1. It also initiates translation from a non-AUG (UUG) codon. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY101179.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2144333, SAMEA2145774 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## non-AUG initiation codon :: PMID: 8921372 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

TTGGAGGGCA CGGCCGGCAC CATTACCTCC AACGAGTGGA GCTCTCCCAC CTCCCCTGAG 
GGGAGCACCG CCTCTGGGGG CAGTCAGGCA CTGGACAAGC CCATCGACAA TGACGCAGAG 
GGCGTGTGGA GCCCGGATAT TGAGCAGAGT TTCCAGGAGG CCCTCGCCAT CTACCCGCCC 
TGTGGCAGGC GCAAAATCAT CCTGTCGGAC GAGGGCAAGA TGTATGGTCG GAACGAGCTG 
ATTGCCCGCT ACATCAAGCT CCGGACAGGG AAGACCCGCA CCAGGAAGCA GGTCTCCAGC 
CACATCCAGG TGCTGGCTCG TCGCAAAGCT CGCGAGATCC AGGCCAAGCT AAAGTTTTGG 
CAAGGAGCTT TGCCAGGCCA AGCCGGAACG TCCCATGATG TGAAGCCTTT CTCTCAGCAA 
ACCTATGCTG TCCAGCCTCC GCTGCCTCTG CCAGGGTTTG AGTCTCCTGC AGGGCCCGCC 
CCATCGCCCT CTGCGCCCCC GGCACCCCCA TGGCAGGGCC GCAGCGTGGC CAGCTCCAAG 
CTCTGGATGT TGGAGTTCTC TGCCTTCCTG GAGCAGCAGC AGGACCCGGA CACGTACAAC 
AAGCACCTGT TCGTGCACAT TGGCCAGTCC AGCCCAAGCT ACAGCGACCC CTACCTCGAA 
GCCGTGGACA TCCGCCAAAT CTATGACAAA TTCCCGGAGA AAAAGGGTGG ACTCAAGGAT 
CTCTTCGAAC GGGGACCCTC CAATGCCTTT TTTCTTGTGA AGTTCTGGGC AGACCTCAAC 
ACCAACATCG AGGATGAAGG CAGCTCCTTC TATGGGGTCT CCAGCCAGTA TGAGAGCCCC 
GAGAACATGA TCATCACCTG CTCCACGAAG GTCTGCTCTT TCGGCAAGCA GGTGGTGGAG 
AAAGTTGAGA CAGAGTATGC TCGCTATGAG AATGGACACT ACTCTTACCG CATCCACCGG 
TCCCCGCTCT GTGAGTACAT GATCAACTTC ATCCACAAGC TCAAGCACCT CCCTGAGAAG 
TACATGATGA ACAGCGTGCT GGAGAACTTC ACCATCCTGC AGGTGGTCAC CAACAGAGAC 
ACACAGGAGA CCTTGCTGTG CATTGCCTAT GTCTTTGAGG TGTCAGCCAG TGAGCACGGG 
GCTCAGCACC ACATCTACAG GCTGGTGAAA GAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_958849.1
CDS	293..1468
Translation	LEGTAGTITSNEWSSPTSPEGSTASGGSQALDKPIDNDAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKAREIQAKLKFWQGALPGQAGTSHDVKPFSQQTYAVQPPLPLPGFESPAGPAPSPSAPPAPPWQGRSVASSKLWMLEFSAFLEQQQDPDTYNKHLFVHIGQSSPSYSDPYLEAVDIRQIYDKFPEKKGGLKDLFERGPSNAFFLVKFWADLNTNIEDEGSSFYGVSSQYESPENMIITCSTKVCSFGKQVVEKVETEYARYENGHYSYRIHRSPLCEYMINFIHKLKHLPEKYMMNSVLENFTILQVVTNRDTQETLLCIAYVFEVSASEHGAQHHIYRLVKE

Target ORF information:

RefSeq Version	NM_201441.2
Organism	Homo sapiens(human)
Definition	Homo sapiens TEA domain transcription factor 4 (TEAD4), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_201441.2

ORF Insert Sequence:

TTGGAGGGCA CGGCCGGCAC CATTACCTCC AACGAGTGGA GCTCTCCCAC CTCCCCTGAG 
GGGAGCACCG CCTCTGGGGG CAGTCAGGCA CTGGACAAGC CCATCGACAA TGACGCAGAG 
GGCGTGTGGA GCCCGGATAT TGAGCAGAGT TTCCAGGAGG CCCTCGCCAT CTACCCGCCC 
TGTGGCAGGC GCAAAATCAT CCTGTCGGAC GAGGGCAAGA TGTATGGTCG GAACGAGCTG 
ATTGCCCGCT ACATCAAGCT CCGGACAGGG AAGACCCGCA CCAGGAAGCA GGTCTCCAGC 
CACATCCAGG TGCTGGCTCG TCGCAAAGCT CGCGAGATCC AGGCCAAGCT AAAGTTTTGG 
CAAGGAGCTT TGCCAGGCCA AGCCGGAACG TCCCATGATG TGAAGCCTTT CTCTCAGCAA 
ACCTATGCTG TCCAGCCTCC GCTGCCTCTG CCAGGGTTTG AGTCTCCTGC AGGGCCCGCC 
CCATCGCCCT CTGCGCCCCC GGCACCCCCA TGGCAGGGCC GCAGCGTGGC CAGCTCCAAG 
CTCTGGATGT TGGAGTTCTC TGCCTTCCTG GAGCAGCAGC AGGACCCGGA CACGTACAAC 
AAGCACCTGT TCGTGCACAT TGGCCAGTCC AGCCCAAGCT ACAGCGACCC CTACCTCGAA 
GCCGTGGACA TCCGCCAAAT CTATGACAAA TTCCCGGAGA AAAAGGGTGG ACTCAAGGAT 
CTCTTCGAAC GGGGACCCTC CAATGCCTTT TTTCTTGTGA AGTTCTGGGC AGACCTCAAC 
ACCAACATCG AGGATGAAGG CAGCTCCTTC TATGGGGTCT CCAGCCAGTA TGAGAGCCCC 
GAGAACATGA TCATCACCTG CTCCACGAAG GTCTGCTCTT TCGGCAAGCA GGTGGTGGAG 
AAAGTTGAGA CAGAGTATGC TCGCTATGAG AATGGACACT ACTCTTACCG CATCCACCGG 
TCCCCGCTCT GTGAGTACAT GATCAACTTC ATCCACAAGC TCAAGCACCT CCCTGAGAAG 
TACATGATGA ACAGCGTGCT GGAGAACTTC ACCATCCTGC AGGTGGTCAC CAACAGAGAC 
ACACAGGAGA CCTTGCTGTG CATTGCCTAT GTCTTTGAGG TGTCAGCCAG TGAGCACGGG 
GCTCAGCACC ACATCTACAG GCTGGTGAAA GAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TEAD4 ( NM_201441.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_958849.1 Homo sapiens TEA domain transcription factor 4 (TEAD4), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu23981
Clone ID Related Accession (Same CDS sequence)	NM_201441.2 , NM_201441.3
Accession Version	NM_201441.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1176bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-15
Organism	Homo sapiens(human)
Product	transcriptional enhancer factor TEF-3 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AY101179.1, BM555991.1 and U63824.1. On Jun 2, 2019 this sequence version replaced NM_201441.2. Transcript Variant: This variant (2) lacks an in-frame coding exon compared to variant 1, resulting in an isoform (2) that is missing an internal segment compared to isoform 1. It also initiates translation from a non-AUG (UUG) codon. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY101179.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2144333, SAMEA2145774 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## non-AUG initiation codon :: PMID: 8921372 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

TTGGAGGGCA CGGCCGGCAC CATTACCTCC AACGAGTGGA GCTCTCCCAC CTCCCCTGAG 
GGGAGCACCG CCTCTGGGGG CAGTCAGGCA CTGGACAAGC CCATCGACAA TGACGCAGAG 
GGCGTGTGGA GCCCGGATAT TGAGCAGAGT TTCCAGGAGG CCCTCGCCAT CTACCCGCCC 
TGTGGCAGGC GCAAAATCAT CCTGTCGGAC GAGGGCAAGA TGTATGGTCG GAACGAGCTG 
ATTGCCCGCT ACATCAAGCT CCGGACAGGG AAGACCCGCA CCAGGAAGCA GGTCTCCAGC 
CACATCCAGG TGCTGGCTCG TCGCAAAGCT CGCGAGATCC AGGCCAAGCT AAAGTTTTGG 
CAAGGAGCTT TGCCAGGCCA AGCCGGAACG TCCCATGATG TGAAGCCTTT CTCTCAGCAA 
ACCTATGCTG TCCAGCCTCC GCTGCCTCTG CCAGGGTTTG AGTCTCCTGC AGGGCCCGCC 
CCATCGCCCT CTGCGCCCCC GGCACCCCCA TGGCAGGGCC GCAGCGTGGC CAGCTCCAAG 
CTCTGGATGT TGGAGTTCTC TGCCTTCCTG GAGCAGCAGC AGGACCCGGA CACGTACAAC 
AAGCACCTGT TCGTGCACAT TGGCCAGTCC AGCCCAAGCT ACAGCGACCC CTACCTCGAA 
GCCGTGGACA TCCGCCAAAT CTATGACAAA TTCCCGGAGA AAAAGGGTGG ACTCAAGGAT 
CTCTTCGAAC GGGGACCCTC CAATGCCTTT TTTCTTGTGA AGTTCTGGGC AGACCTCAAC 
ACCAACATCG AGGATGAAGG CAGCTCCTTC TATGGGGTCT CCAGCCAGTA TGAGAGCCCC 
GAGAACATGA TCATCACCTG CTCCACGAAG GTCTGCTCTT TCGGCAAGCA GGTGGTGGAG 
AAAGTTGAGA CAGAGTATGC TCGCTATGAG AATGGACACT ACTCTTACCG CATCCACCGG 
TCCCCGCTCT GTGAGTACAT GATCAACTTC ATCCACAAGC TCAAGCACCT CCCTGAGAAG 
TACATGATGA ACAGCGTGCT GGAGAACTTC ACCATCCTGC AGGTGGTCAC CAACAGAGAC 
ACACAGGAGA CCTTGCTGTG CATTGCCTAT GTCTTTGAGG TGTCAGCCAG TGAGCACGGG 
GCTCAGCACC ACATCTACAG GCTGGTGAAA GAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_958849.1
CDS	208..1383
Translation	LEGTAGTITSNEWSSPTSPEGSTASGGSQALDKPIDNDAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKAREIQAKLKFWQGALPGQAGTSHDVKPFSQQTYAVQPPLPLPGFESPAGPAPSPSAPPAPPWQGRSVASSKLWMLEFSAFLEQQQDPDTYNKHLFVHIGQSSPSYSDPYLEAVDIRQIYDKFPEKKGGLKDLFERGPSNAFFLVKFWADLNTNIEDEGSSFYGVSSQYESPENMIITCSTKVCSFGKQVVEKVETEYARYENGHYSYRIHRSPLCEYMINFIHKLKHLPEKYMMNSVLENFTILQVVTNRDTQETLLCIAYVFEVSASEHGAQHHIYRLVKE

Target ORF information:

RefSeq Version	NM_201441.3
Organism	Homo sapiens(human)
Definition	Homo sapiens TEA domain transcription factor 4 (TEAD4), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_201441.3

ORF Insert Sequence:

TTGGAGGGCA CGGCCGGCAC CATTACCTCC AACGAGTGGA GCTCTCCCAC CTCCCCTGAG 
GGGAGCACCG CCTCTGGGGG CAGTCAGGCA CTGGACAAGC CCATCGACAA TGACGCAGAG 
GGCGTGTGGA GCCCGGATAT TGAGCAGAGT TTCCAGGAGG CCCTCGCCAT CTACCCGCCC 
TGTGGCAGGC GCAAAATCAT CCTGTCGGAC GAGGGCAAGA TGTATGGTCG GAACGAGCTG 
ATTGCCCGCT ACATCAAGCT CCGGACAGGG AAGACCCGCA CCAGGAAGCA GGTCTCCAGC 
CACATCCAGG TGCTGGCTCG TCGCAAAGCT CGCGAGATCC AGGCCAAGCT AAAGTTTTGG 
CAAGGAGCTT TGCCAGGCCA AGCCGGAACG TCCCATGATG TGAAGCCTTT CTCTCAGCAA 
ACCTATGCTG TCCAGCCTCC GCTGCCTCTG CCAGGGTTTG AGTCTCCTGC AGGGCCCGCC 
CCATCGCCCT CTGCGCCCCC GGCACCCCCA TGGCAGGGCC GCAGCGTGGC CAGCTCCAAG 
CTCTGGATGT TGGAGTTCTC TGCCTTCCTG GAGCAGCAGC AGGACCCGGA CACGTACAAC 
AAGCACCTGT TCGTGCACAT TGGCCAGTCC AGCCCAAGCT ACAGCGACCC CTACCTCGAA 
GCCGTGGACA TCCGCCAAAT CTATGACAAA TTCCCGGAGA AAAAGGGTGG ACTCAAGGAT 
CTCTTCGAAC GGGGACCCTC CAATGCCTTT TTTCTTGTGA AGTTCTGGGC AGACCTCAAC 
ACCAACATCG AGGATGAAGG CAGCTCCTTC TATGGGGTCT CCAGCCAGTA TGAGAGCCCC 
GAGAACATGA TCATCACCTG CTCCACGAAG GTCTGCTCTT TCGGCAAGCA GGTGGTGGAG 
AAAGTTGAGA CAGAGTATGC TCGCTATGAG AATGGACACT ACTCTTACCG CATCCACCGG 
TCCCCGCTCT GTGAGTACAT GATCAACTTC ATCCACAAGC TCAAGCACCT CCCTGAGAAG 
TACATGATGA ACAGCGTGCT GGAGAACTTC ACCATCCTGC AGGTGGTCAC CAACAGAGAC 
ACACAGGAGA CCTTGCTGTG CATTGCCTAT GTCTTTGAGG TGTCAGCCAG TGAGCACGGG 
GCTCAGCACC ACATCTACAG GCTGGTGAAA GAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Effect of the acylation of TEAD4 on its interaction with co-activators YAP and TAZ.
Protein science : a publication of the Protein Society26(12)2399-2409(2017 Dec)
Mesrouze Y,Meyerhofer M,Bokhovchuk F,Fontana P,Zimmermann C,Martin T,Delaunay C,Izaac A,Kallen J,Schmelzle T,Erdmann D,Ch?ne P

TEAD1/4 exerts oncogenic role and is negatively regulated by miR-4269 in gastric tumorigenesis.
Oncogene36(47)6518-6530(2017 Nov)
Zhou Y,Huang T,Zhang J,Wong CC,Zhang B,Dong Y,Wu F,Tong JHM,Wu WKK,Cheng ASL,Yu J,Kang W,To KF

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TEAD4 cDNA ORF clone, Homo sapiens(human)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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