| Gene Symbol | RUNX3 |
| Entrez Gene ID | 864 |
| Full Name | runt related transcription factor 3 |
| Synonyms | AML2,CBFA3,PEBP2aC |
| General protein information |
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| Gene Type | protein-coding |
| Organism | Homo sapiens(Human) |
| Genome | |
| Summary | This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]. |
| Disorder MIM: |

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