ALG11 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Gene Symbol	ALG11
Entrez Gene ID	440138
Full Name	ALG11, alpha-1,2-mannosyltransferase
Synonyms	CDG1P,GT8
General protein information	Preferred Names ALG11, alpha-1,2-mannosyltransferase Names GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase GDP-Man:Man(3)GlcNAc(2)-PP-dolichol alpha-1,2-mannosyltransferase asparagine-linked glycosylation 11, alpha-1,2-mannosyltransferase homolog asparagine-linked glycosylation protein 11 homolog glycolipid 2-alpha-mannosyltransferase
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 13 Map Location: 13q14.3
Summary	This gene encodes a GDP-Man:Man3GlcNAc2-PP-dolichol-alpha1,2-mannosyltransferase which is localized to the cytosolic side of the endoplasmic reticulum (ER) and catalyzes the transfer of the fourth and fifth mannose residue from GDP-mannose (GDP-Man) to Man3GlcNAc2-PP-dolichol and Man4GlcNAc2-PP-dolichol resulting in the production of Man5GlcNAc2-PP-dolichol. Mutations in this gene are associated with congenital disorder of glycosylation type Ip (CDGIP). This gene overlaps but is distinct from the UTP14, U3 small nucleolar ribonucleoprotein, homolog C (yeast) gene. A pseudogene of the GDP-Man:Man3GlcNAc2-PP-dolichol-alpha1,2-mannosyltransferase has been identified on chromosome 19. [provided by RefSeq, Aug 2010].
Disorder MIM:	613666
Disorder Html:	Congenital disorder of glycosylation, type Ip, 613661 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001004127.2	NP_001004127.2	GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase
NM_001004127.3	NP_001004127.2	GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase

Pathways from BioSystems

Homologies

Danio rerio (zebrafish)	alg11	NP_001154823.1
Caenorhabditis elegans (roundworm)	B0361.8	NP_498606.1
Homo sapiens (human)	ALG11	NP_001004127.2
Bos taurus (cattle)	ALG11	XP_002691841.2
Mus musculus (house mouse)	Alg11	NP_001230090.1
Magnaporthe oryzae (rice blast fungus)	MGG_03883	XP_003719996.1
Canis lupus familiaris (dog)	ALG11	XP_003433100.2
Rattus norvegicus (Norway rat)	Alg11	NP_001101871.1
Drosophila melanogaster (fruit fly)	CG11306	NP_001262182.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP011324	XP_309328.3
Saccharomyces cerevisiae (baker's yeast)	ALG11	NP_014350.1
Oryza sativa (rice)	Os12g0583000	NP_001067144.2
Xenopus tropicalis (tropical clawed frog)	alg11	NP_989283.1
Schizosaccharomyces pombe (fission yeast)	alg11	NP_587708.1
Gallus gallus (chicken)	ALG11	NP_001186754.1
Kluyveromyces lactis	KLLA0F03817g	XP_455253.1
Eremothecium gossypii	AGOS_ADL235W	NP_983861.1
Neurospora crassa	NCU06779	XP_963620.1
Arabidopsis thaliana (thale cress)	LEW3	NP_181548.2

Gene Ontology
Bibliography

Related articles in PubMed

Cloning and transcriptional expression of mouse mannosyltransferase IV/V cDNA, which is involved in the synthesis of lipid-linked oligosaccharides.
Nishimura Y, Shimono N, Yoshimoto T, Kamiguchi H, Nishikawa Y
Bioscience, biotechnology, and biochemistry78(3)400-9(2014)

Improved diagnostics lead to identification of three new patients with congenital disorder of glycosylation-Ip.
Thiel C, Rind N, Popovici D, Hoffmann GF, Hanson K, Conway RL, Adamski CR, Butler E, Scanlon R, Lambert M, Apeshiotis N, Thiels C, Matthijs G, K?rner C
Human mutation33(3)485-7(2012 Mar)

A severe human metabolic disease caused by deficiency of the endoplasmatic mannosyltransferase hALG11 leads to congenital disorder of glycosylation-Ip.
Rind N, Schmeiser V, Thiel C, Absmanner B, L?bbehusen J, Hocks J, Apeshiotis N, Wilichowski E, Lehle L, K?rner C
Human molecular genetics19(8)1413-24(2010 Apr)

Defining the membrane proteome of NK cells.
Ghosh D, Lippert D, Krokhin O, Cortens JP, Wilkins JA
Journal of mass spectrometry : JMS45(1)1-25(2010 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Hence, we concluded that there is different transcriptional control mechanism between mALG11 and hALG11
Title: Cloning and transcriptional expression of mouse mannosyltransferase IV/V cDNA, which is involved in the synthesis of lipid-linked oligosaccharides.

After identifying the congenital disorders of glycosylation-Ip index patient, study describe three more cases suffering from an ALG11 deficiency.
Title: Improved diagnostics lead to identification of three new patients with congenital disorder of glycosylation-Ip.

Deficiency of the endoplasmatic mannosyltransferase hALG11 leads to congenital disorder of glycosylation.
Title: A severe human metabolic disease caused by deficiency of the endoplasmatic mannosyltransferase hALG11 leads to congenital disorder of glycosylation-Ip.

The following ALG11 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ALG11 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu22573	NM_001004127.3 Latest version!	Homo sapiens ALG11 alpha-1,2-mannosyltransferase (ALG11), transcript variant A, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$286.30 $409.00
View Old Accession Versions >>
OHu22573	NM_001004127.2	Homo sapiens ALG11, alpha-1,2-mannosyltransferase (ALG11), transcript variant A, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$286.30 $409.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ALG11 ( NM_001004127.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001004127.2 Homo sapiens ALG11, alpha-1,2-mannosyltransferase (ALG11), transcript variant A, mRNA.

Price & Availability↑

CloneID	OHu22573
Clone ID Related Accession (Same CDS sequence)	NM_001004127.2 , NM_001004127.3
Accession Version	NM_001004127.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1479bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC366525.1, BC142998.1, AL139082.18 and AK025456.1. This sequence is a reference standard in the RefSeqGene project. On Aug 25, 2010 this sequence version replaced NM_001004127.1. Transcript Variant: This variant (A) represents the longer transcript and encodes the functional protein. ##Evidence-Data-START## Transcript exon combination :: AK025456.1, SRR1660809.263344.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGGCCG GCGAAAGGAG CTGGTGCCTG TGCAAGTTGT TGAGGTTTTT TTATTCATTA 
TTCTTCCCTG GGCTCATTGT ATGTGGAACT TTATGTGTGT GTTTGGTCAT TGTCCTTTGG 
GGAATCAGAC TGCTGCTACA GAGAAAGAAA AAATTAGTGT CAACTAGCAA AAATGGGAAA 
AATCAAATGG TGATTGCATT TTTTCATCCA TACTGCAATG CTGGTGGAGG AGGAGAAAGA 
GTTTTATGGT GTGCTTTAAG AGCCCTGCAG AAAAAGTATC CTGAAGCAGT TTATGTTGTT 
TATACCGGCG ATGTTAATGT CAACGGTCAA CAGATACTAG AAGGTGCTTT CAGAAGATTT 
AACATCAGAT TAATTCACCC AGTGCAGTTT GTTTTTTTAA GGAAACGCTA TCTTGTGGAA 
GATTCACTGT ATCCTCACTT CACACTGCTG GGCCAAAGTC TAGGATCCAT TTTTCTTGGC 
TGGGAAGCTC TAATGCAGTG TGTTCCTGAT GTTTACATTG ATTCAATGGG ATACGCTTTT 
ACGCTTCCTC TGTTTAAGTA TATAGGGGGT TGCCAAGTTG GAAGCTATGT TCATTATCCT 
ACTATCAGCA CCGACATGCT CTCTGTAGTG AAGAATCAAA ATATTGGATT TAATAATGCA 
GCCTTCATTA CCAGGAATCC TTTTCTCAGC AAAGTAAAGC TCATCTACTA CTATTTATTT 
GCTTTTATTT ATGGACTTGT TGGTTCTTGC AGTGATGTAG TCATGGTCAA TTCTTCTTGG 
ACACTAAACC ATATTCTCTC ACTATGGAAA GTTGGGAATT GCACTAACAT TGTTTATCCA 
CCTTGTGATG TGCAGACATT TCTGGACATT CCCTTACATG AGAAAAAGAT GACCCCAGGA 
CATTTGCTGG TTTCTGTTGG CCAGTTTAGG CCGGAAAAGA ATCATCCATT GCAGATCAGA 
GCCTTTGCTA AATTGCTGAA TAAGAAGATG GTTGAGTCAC CTCCTTCGCT TAAACTTGTC 
CTCATTGGAG GTTGTCGTAA CAAAGATGAT GAACTTAGGG TAAACCAACT GAGAAGGCTG 
TCTGAGGATT TAGGAGTTCA AGAATATGTG GAATTTAAAA TAAACATTCC ATTTGATGAA 
TTAAAGAATT ATTTGTCTGA AGCAACAATT GGTCTGCATA CCATGTGGAA CGAGCATTTT 
GGGATTGGAG TTGTGGAGTG TATGGCAGCT GGCACAATTA TCCTTGCACA CAATTCGGGG 
GGCCCAAAGC TTGACATTGT GGTTCCTCAC GAAGGAGATA TAACTGGCTT TCTGGCTGAG 
AGTGAAGAAG ACTATGCTGA AACTATCGCT CACATTCTTT CCATGTCTGC AGAAAAGAGA 
CTCCAAATCA GAAAAAGTGC TCGTGCATCT GTAAGCAGAT TCTCTGATCA GGAATTTGAA 
GTGACATTCC TATCATCTGT GGAAAAGTTA TTTAAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001004127.2
CDS	33..1511
Translation	MAAGERSWCLCKLLRFFYSLFFPGLIVCGTLCVCLVIVLWGIRLLLQRKKKLVSTSKNGKNQMVIAFFHPYCNAGGGGERVLWCALRALQKKYPEAVYVVYTGDVNVNGQQILEGAFRRFNIRLIHPVQFVFLRKRYLVEDSLYPHFTLLGQSLGSIFLGWEALMQCVPDVYIDSMGYAFTLPLFKYIGGCQVGSYVHYPTISTDMLSVVKNQNIGFNNAAFITRNPFLSKVKLIYYYLFAFIYGLVGSCSDVVMVNSSWTLNHILSLWKVGNCTNIVYPPCDVQTFLDIPLHEKKMTPGHLLVSVGQFRPEKNHPLQIRAFAKLLNKKMVESPPSLKLVLIGGCRNKDDELRVNQLRRLSEDLGVQEYVEFKINIPFDELKNYLSEATIGLHTMWNEHFGIGVVECMAAGTIILAHNSGGPKLDIVVPHEGDITGFLAESEEDYAETIAHILSMSAEKRLQIRKSARASVSRFSDQEFEVTFLSSVEKLFK

Target ORF information:

RefSeq Version	NM_001004127.2
Organism	Homo sapiens(human)
Definition	Homo sapiens ALG11, alpha-1,2-mannosyltransferase (ALG11), transcript variant A, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001004127.2

ORF Insert Sequence:

ATGGCGGCCG GCGAAAGGAG CTGGTGCCTG TGCAAGTTGT TGAGGTTTTT TTATTCATTA 
TTCTTCCCTG GGCTCATTGT ATGTGGAACT TTATGTGTGT GTTTGGTCAT TGTCCTTTGG 
GGAATCAGAC TGCTGCTACA GAGAAAGAAA AAATTAGTGT CAACTAGCAA AAATGGGAAA 
AATCAAATGG TGATTGCATT TTTTCATCCA TACTGCAATG CTGGTGGAGG AGGAGAAAGA 
GTTTTATGGT GTGCTTTAAG AGCCCTGCAG AAAAAGTATC CTGAAGCAGT TTATGTTGTT 
TATACCGGCG ATGTTAATGT CAACGGTCAA CAGATACTAG AAGGTGCTTT CAGAAGATTT 
AACATCAGAT TAATTCACCC AGTGCAGTTT GTTTTTTTAA GGAAACGCTA TCTTGTGGAA 
GATTCACTGT ATCCTCACTT CACACTGCTG GGCCAAAGTC TAGGATCCAT TTTTCTTGGC 
TGGGAAGCTC TAATGCAGTG TGTTCCTGAT GTTTACATTG ATTCAATGGG ATACGCTTTT 
ACGCTTCCTC TGTTTAAGTA TATAGGGGGT TGCCAAGTTG GAAGCTATGT TCATTATCCT 
ACTATCAGCA CCGACATGCT CTCTGTAGTG AAGAATCAAA ATATTGGATT TAATAATGCA 
GCCTTCATTA CCAGGAATCC TTTTCTCAGC AAAGTAAAGC TCATCTACTA CTATTTATTT 
GCTTTTATTT ATGGACTTGT TGGTTCTTGC AGTGATGTAG TCATGGTCAA TTCTTCTTGG 
ACACTAAACC ATATTCTCTC ACTATGGAAA GTTGGGAATT GCACTAACAT TGTTTATCCA 
CCTTGTGATG TGCAGACATT TCTGGACATT CCCTTACATG AGAAAAAGAT GACCCCAGGA 
CATTTGCTGG TTTCTGTTGG CCAGTTTAGG CCGGAAAAGA ATCATCCATT GCAGATCAGA 
GCCTTTGCTA AATTGCTGAA TAAGAAGATG GTTGAGTCAC CTCCTTCGCT TAAACTTGTC 
CTCATTGGAG GTTGTCGTAA CAAAGATGAT GAACTTAGGG TAAACCAACT GAGAAGGCTG 
TCTGAGGATT TAGGAGTTCA AGAATATGTG GAATTTAAAA TAAACATTCC ATTTGATGAA 
TTAAAGAATT ATTTGTCTGA AGCAACAATT GGTCTGCATA CCATGTGGAA CGAGCATTTT 
GGGATTGGAG TTGTGGAGTG TATGGCAGCT GGCACAATTA TCCTTGCACA CAATTCGGGG 
GGCCCAAAGC TTGACATTGT GGTTCCTCAC GAAGGAGATA TAACTGGCTT TCTGGCTGAG 
AGTGAAGAAG ACTATGCTGA AACTATCGCT CACATTCTTT CCATGTCTGC AGAAAAGAGA 
CTCCAAATCA GAAAAAGTGC TCGTGCATCT GTAAGCAGAT TCTCTGATCA GGAATTTGAA 
GTGACATTCC TATCATCTGT GGAAAAGTTA TTTAAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ALG11 ( NM_001004127.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001004127.2 Homo sapiens ALG11 alpha-1,2-mannosyltransferase (ALG11), transcript variant A, mRNA.

Price & Availability↑

CloneID	OHu22573
Clone ID Related Accession (Same CDS sequence)	NM_001004127.2 , NM_001004127.3
Accession Version	NM_001004127.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1479bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-06
Organism	Homo sapiens(human)
Product	GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC142998.1, AL139082.18 and AK025456.1. On Nov 23, 2018 this sequence version replaced NM_001004127.2. Transcript Variant: This variant (A) represents the longer transcript and encodes the functional protein. ##Evidence-Data-START## Transcript exon combination :: SRR1803613.25155.1, SRR1803611.170960.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000521508.2/ ENSP00000430236.1 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCGGCCG GCGAAAGGAG CTGGTGCCTG TGCAAGTTGT TGAGGTTTTT TTATTCATTA 
TTCTTCCCTG GGCTCATTGT ATGTGGAACT TTATGTGTGT GTTTGGTCAT TGTCCTTTGG 
GGAATCAGAC TGCTGCTACA GAGAAAGAAA AAATTAGTGT CAACTAGCAA AAATGGGAAA 
AATCAAATGG TGATTGCATT TTTTCATCCA TACTGCAATG CTGGTGGAGG AGGAGAAAGA 
GTTTTATGGT GTGCTTTAAG AGCCCTGCAG AAAAAGTATC CTGAAGCAGT TTATGTTGTT 
TATACCGGCG ATGTTAATGT CAACGGTCAA CAGATACTAG AAGGTGCTTT CAGAAGATTT 
AACATCAGAT TAATTCACCC AGTGCAGTTT GTTTTTTTAA GGAAACGCTA TCTTGTGGAA 
GATTCACTGT ATCCTCACTT CACACTGCTG GGCCAAAGTC TAGGATCCAT TTTTCTTGGC 
TGGGAAGCTC TAATGCAGTG TGTTCCTGAT GTTTACATTG ATTCAATGGG ATACGCTTTT 
ACGCTTCCTC TGTTTAAGTA TATAGGGGGT TGCCAAGTTG GAAGCTATGT TCATTATCCT 
ACTATCAGCA CCGACATGCT CTCTGTAGTG AAGAATCAAA ATATTGGATT TAATAATGCA 
GCCTTCATTA CCAGGAATCC TTTTCTCAGC AAAGTAAAGC TCATCTACTA CTATTTATTT 
GCTTTTATTT ATGGACTTGT TGGTTCTTGC AGTGATGTAG TCATGGTCAA TTCTTCTTGG 
ACACTAAACC ATATTCTCTC ACTATGGAAA GTTGGGAATT GCACTAACAT TGTTTATCCA 
CCTTGTGATG TGCAGACATT TCTGGACATT CCCTTACATG AGAAAAAGAT GACCCCAGGA 
CATTTGCTGG TTTCTGTTGG CCAGTTTAGG CCGGAAAAGA ATCATCCATT GCAGATCAGA 
GCCTTTGCTA AATTGCTGAA TAAGAAGATG GTTGAGTCAC CTCCTTCGCT TAAACTTGTC 
CTCATTGGAG GTTGTCGTAA CAAAGATGAT GAACTTAGGG TAAACCAACT GAGAAGGCTG 
TCTGAGGATT TAGGAGTTCA AGAATATGTG GAATTTAAAA TAAACATTCC ATTTGATGAA 
TTAAAGAATT ATTTGTCTGA AGCAACAATT GGTCTGCATA CCATGTGGAA CGAGCATTTT 
GGGATTGGAG TTGTGGAGTG TATGGCAGCT GGCACAATTA TCCTTGCACA CAATTCGGGG 
GGCCCAAAGC TTGACATTGT GGTTCCTCAC GAAGGAGATA TAACTGGCTT TCTGGCTGAG 
AGTGAAGAAG ACTATGCTGA AACTATCGCT CACATTCTTT CCATGTCTGC AGAAAAGAGA 
CTCCAAATCA GAAAAAGTGC TCGTGCATCT GTAAGCAGAT TCTCTGATCA GGAATTTGAA 
GTGACATTCC TATCATCTGT GGAAAAGTTA TTTAAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001004127.2
CDS	22..1500
Translation	MAAGERSWCLCKLLRFFYSLFFPGLIVCGTLCVCLVIVLWGIRLLLQRKKKLVSTSKNGKNQMVIAFFHPYCNAGGGGERVLWCALRALQKKYPEAVYVVYTGDVNVNGQQILEGAFRRFNIRLIHPVQFVFLRKRYLVEDSLYPHFTLLGQSLGSIFLGWEALMQCVPDVYIDSMGYAFTLPLFKYIGGCQVGSYVHYPTISTDMLSVVKNQNIGFNNAAFITRNPFLSKVKLIYYYLFAFIYGLVGSCSDVVMVNSSWTLNHILSLWKVGNCTNIVYPPCDVQTFLDIPLHEKKMTPGHLLVSVGQFRPEKNHPLQIRAFAKLLNKKMVESPPSLKLVLIGGCRNKDDELRVNQLRRLSEDLGVQEYVEFKINIPFDELKNYLSEATIGLHTMWNEHFGIGVVECMAAGTIILAHNSGGPKLDIVVPHEGDITGFLAESEEDYAETIAHILSMSAEKRLQIRKSARASVSRFSDQEFEVTFLSSVEKLFK

Target ORF information:

RefSeq Version	NM_001004127.3
Organism	Homo sapiens(human)
Definition	Homo sapiens ALG11 alpha-1,2-mannosyltransferase (ALG11), transcript variant A, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001004127.3

ORF Insert Sequence:

ATGGCGGCCG GCGAAAGGAG CTGGTGCCTG TGCAAGTTGT TGAGGTTTTT TTATTCATTA 
TTCTTCCCTG GGCTCATTGT ATGTGGAACT TTATGTGTGT GTTTGGTCAT TGTCCTTTGG 
GGAATCAGAC TGCTGCTACA GAGAAAGAAA AAATTAGTGT CAACTAGCAA AAATGGGAAA 
AATCAAATGG TGATTGCATT TTTTCATCCA TACTGCAATG CTGGTGGAGG AGGAGAAAGA 
GTTTTATGGT GTGCTTTAAG AGCCCTGCAG AAAAAGTATC CTGAAGCAGT TTATGTTGTT 
TATACCGGCG ATGTTAATGT CAACGGTCAA CAGATACTAG AAGGTGCTTT CAGAAGATTT 
AACATCAGAT TAATTCACCC AGTGCAGTTT GTTTTTTTAA GGAAACGCTA TCTTGTGGAA 
GATTCACTGT ATCCTCACTT CACACTGCTG GGCCAAAGTC TAGGATCCAT TTTTCTTGGC 
TGGGAAGCTC TAATGCAGTG TGTTCCTGAT GTTTACATTG ATTCAATGGG ATACGCTTTT 
ACGCTTCCTC TGTTTAAGTA TATAGGGGGT TGCCAAGTTG GAAGCTATGT TCATTATCCT 
ACTATCAGCA CCGACATGCT CTCTGTAGTG AAGAATCAAA ATATTGGATT TAATAATGCA 
GCCTTCATTA CCAGGAATCC TTTTCTCAGC AAAGTAAAGC TCATCTACTA CTATTTATTT 
GCTTTTATTT ATGGACTTGT TGGTTCTTGC AGTGATGTAG TCATGGTCAA TTCTTCTTGG 
ACACTAAACC ATATTCTCTC ACTATGGAAA GTTGGGAATT GCACTAACAT TGTTTATCCA 
CCTTGTGATG TGCAGACATT TCTGGACATT CCCTTACATG AGAAAAAGAT GACCCCAGGA 
CATTTGCTGG TTTCTGTTGG CCAGTTTAGG CCGGAAAAGA ATCATCCATT GCAGATCAGA 
GCCTTTGCTA AATTGCTGAA TAAGAAGATG GTTGAGTCAC CTCCTTCGCT TAAACTTGTC 
CTCATTGGAG GTTGTCGTAA CAAAGATGAT GAACTTAGGG TAAACCAACT GAGAAGGCTG 
TCTGAGGATT TAGGAGTTCA AGAATATGTG GAATTTAAAA TAAACATTCC ATTTGATGAA 
TTAAAGAATT ATTTGTCTGA AGCAACAATT GGTCTGCATA CCATGTGGAA CGAGCATTTT 
GGGATTGGAG TTGTGGAGTG TATGGCAGCT GGCACAATTA TCCTTGCACA CAATTCGGGG 
GGCCCAAAGC TTGACATTGT GGTTCCTCAC GAAGGAGATA TAACTGGCTT TCTGGCTGAG 
AGTGAAGAAG ACTATGCTGA AACTATCGCT CACATTCTTT CCATGTCTGC AGAAAAGAGA 
CTCCAAATCA GAAAAAGTGC TCGTGCATCT GTAAGCAGAT TCTCTGATCA GGAATTTGAA 
GTGACATTCC TATCATCTGT GGAAAAGTTA TTTAAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Cloning and transcriptional expression of mouse mannosyltransferase IV/V cDNA, which is involved in the synthesis of lipid-linked oligosaccharides.
Bioscience, biotechnology, and biochemistry78(3)400-9(2014)
Nishimura Y,Shimono N,Yoshimoto T,Kamiguchi H,Nishikawa Y

Improved diagnostics lead to identification of three new patients with congenital disorder of glycosylation-Ip.
Human mutation33(3)485-7(2012 Mar)
Thiel C,Rind N,Popovici D,Hoffmann GF,Hanson K,Conway RL,Adamski CR,Butler E,Scanlon R,Lambert M,Apeshiotis N,Thiels C,Matthijs G,K?rner C

A severe human metabolic disease caused by deficiency of the endoplasmatic mannosyltransferase hALG11 leads to congenital disorder of glycosylation-Ip.
Human molecular genetics19(8)1413-24(2010 Apr)
Rind N,Schmeiser V,Thiel C,Absmanner B,L?bbehusen J,Hocks J,Apeshiotis N,Wilichowski E,Lehle L,K?rner C

Defining the membrane proteome of NK cells.
Journal of mass spectrometry : JMS45(1)1-25(2010 Jan)
Ghosh D,Lippert D,Krokhin O,Cortens JP,Wilkins JA

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ALG11 cDNA ORF clone, Homo sapiens(human)

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