CCRL2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Gene Symbol	CCRL2
Entrez Gene ID	9034
Full Name	C-C motif chemokine receptor like 2
Synonyms	ACKR5,CKRX,CRAM,CRAM-A,CRAM-B,HCR
General protein information	Preferred Names C-C motif chemokine receptor like 2 Names C-C chemokine receptor-like 2 atypical chemokine receptor 5 chemokine (C-C motif) receptor-like 2 chemokine receptor CCR11 chemokine receptor X putative MCP-1 chemokine receptor
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 3 Map Location: 3p21.31
Summary	This gene encodes a chemokine receptor like protein, which is predicted to be a seven transmembrane protein and most closely related to CCR1. Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. This gene is expressed at high levels in primary neutrophils and primary monocytes, and is further upregulated on neutrophil activation and during monocyte to macrophage differentiation. The function of this gene is unknown. This gene is mapped to the region where the chemokine receptor gene cluster is located. [provided by RefSeq, Jul 2008].
Disorder MIM:	608379

mRNA and Protein(s)

mRNA	Protein	Name
NM_001130910.2	NP_001124382.1	C-C chemokine receptor-like 2 isoform 2
XM_017007436.1	XP_016862925.1	C-C chemokine receptor-like 2 isoform X1
XM_011534209.1	XP_011532511.1	C-C chemokine receptor-like 2 isoform X1
NM_001130910.1	NP_001124382.1	C-C chemokine receptor-like 2 isoform 2
XM_011534208.1	XP_011532510.1	C-C chemokine receptor-like 2 isoform X1
NM_003965.4	NP_003956.2	C-C chemokine receptor-like 2 isoform 1
NM_003965.5	NP_003956.2	C-C chemokine receptor-like 2 isoform 1

Pathways from BioSystems

Homologies

Homo sapiens (human)	CCRL2	NP_001124382.1
Mus musculus (house mouse)	Ccrl2	NP_059494.2
Canis lupus familiaris (dog)	LOC484788	XP_005632684.1
Rattus norvegicus (Norway rat)	Ccrl2	NP_001101661.1
Pan troglodytes (chimpanzee)	CCRL2	XP_001149932.2
	LOC713715	XP_001103165.2
Bos taurus (cattle)	LOC515976	NP_001069200.1

Gene Ontology
Bibliography

Related articles in PubMed

Chemokine (CC-motif) receptor-like 2 mRNA is expressed in hepatic stellate cells and is positively associated with characteristics of non-alcoholic steatohepatitis in mice and men.
Zimny S, Pohl R, Rein-Fischboeck L, Haberl EM, Krautbauer S, Weiss TS, Buechler C
Experimental and molecular pathology103(1)1-8(2017 08)

CRAM-A indicates IFN-?-associated inflammatory response in breast cancer.
Sarmadi P, Tunali G, Esendagli-Yilmaz G, Yilmaz KB, Esendagli G
Molecular immunology68(2 Pt C)692-8(2015 Dec)

The human chemokine receptor CCRL2 suppresses chemotaxis and invasion by blocking CCL2-induced phosphorylation of p38 MAPK in human breast cancer cells.
Wang LP, Cao J, Zhang J, Wang BY, Hu XC, Shao ZM, Wang ZH, Ou ZL
Medical oncology (Northwood, London, England)32(11)254(2015 Nov)

Genome-wide association study of CSF levels of 59 alzheimer's disease candidate proteins: significant associations with proteins involved in amyloid processing and inflammation.
Kauwe JS, Bailey MH, Ridge PG, Perry R, Wadsworth ME, Hoyt KL, Staley LA, Karch CM, Harari O, Cruchaga C, Ainscough BJ, Bales K, Pickering EH, Bertelsen S, , Fagan AM, Holtzman DM, Morris JC, Goate AM
PLoS genetics10(10)e1004758(2014 Oct)

Elevated chemokine CC-motif receptor-like 2 (CCRL2) promotes cell migration and invasion in glioblastoma.
Yin F, Xu Z, Wang Z, Yao H, Shen Z, Yu F, Tang Y, Fu D, Lin S, Lu G, Kung HF, Poon WS, Huang Y, Lin MC
Biochemical and biophysical research communications429(3-4)168-72(2012 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

CCRL2 mRNA was not significantly changed in murine and human non-alcoholic steatohepatitis liver. CCRL2 mRNA levels were positively correlated with inflammation, fibrosis and NASH scores in the patients.
Title: Chemokine (CC-motif) receptor-like 2 mRNA is expressed in hepatic stellate cells and is positively associated with characteristics of non-alcoholic steatohepatitis in mice and men.

in breast cancer, CRAM-A becomes specifically upregulated under inflammatory stimuli and may serve as a potential marker of immune response.
Title: CRAM-A indicates IFN-?-associated inflammatory response in breast cancer.

CCRL2 inhibited the growth of breast cancer cells in vitro and in vivo.
Title: The human chemokine receptor CCRL2 suppresses chemotaxis and invasion by blocking CCL2-induced phosphorylation of p38 MAPK in human breast cancer cells.

these results suggest for the first time that elevated CCRL2 in glioma promotes cell migration and invasion.
Title: Elevated chemokine CC-motif receptor-like 2 (CCRL2) promotes cell migration and invasion in glioblastoma.

Considering the newly defined role of CCRL2 in lung dendritic cell trafficking, this atypical chemokine receptor may affect pneumocystis pneumonia through immune regulation and inducing inflammation.
Title: Role of exonic variation in chemokine receptor genes on AIDS: CCRL2 F167Y association with pneumocystis pneumonia.

The following CCRL2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CCRL2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu07091	NM_001130910.2 Latest version!	Homo sapiens C-C motif chemokine receptor like 2 (CCRL2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$209.30 $299.00
OHu29384	NM_003965.5 Latest version!	Homo sapiens C-C motif chemokine receptor like 2 (CCRL2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00
OHu29384	XM_011534209.1 Latest version!	Homo sapiens C-C motif chemokine receptor like 2 (CCRL2), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00
OHu29384	XM_017007436.1 Latest version!	Homo sapiens C-C motif chemokine receptor like 2 (CCRL2), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00
OHu29384	XM_011534208.1 Latest version!	Homo sapiens C-C motif chemokine receptor like 2 (CCRL2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00
View Old Accession Versions >>
OHu07091	NM_001130910.1	Homo sapiens C-C motif chemokine receptor like 2 (CCRL2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$209.30 $299.00
OHu29384	NM_003965.4	Homo sapiens C-C motif chemokine receptor like 2 (CCRL2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CCRL2 ( NM_001130910.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001124382.1 Homo sapiens C-C motif chemokine receptor like 2 (CCRL2), transcript variant 2, mRNA.

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CloneID	OHu07091
Clone ID Related Accession (Same CDS sequence)	NM_001130910.2 , NM_001130910.1
Accession Version	NM_001130910.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1071bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-30
Organism	Homo sapiens(human)
Product	C-C chemokine receptor-like 2 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK296673.1, AF015524.1 and AC098613.2. On May 31, 2019 this sequence version replaced NM_001130910.1. Transcript Variant: This variant (2) differs in the 5' UTR and coding region, compared to variant 1, resulting in a longer isoform (2) that has a distinct N-terminus, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF015524.1, AK296673.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGATCTACA CCCGTTTCTT AAAAGGCAGT CTGAAGATGG CCAATTACAC GCTGGCACCA 
GAGGATGAAT ATGATGTCCT CATAGAAGGT GAACTGGAGA GCGATGAGGC AGAGCAATGT 
GACAAGTATG ACGCCCAGGC ACTCTCAGCC CAGCTGGTGC CATCACTCTG CTCTGCTGTG 
TTTGTGATCG GTGTCCTGGA CAATCTCCTG GTTGTGCTTA TCCTGGTAAA ATATAAAGGA 
CTCAAACGCG TGGAAAATAT CTATCTTCTA AACTTGGCAG TTTCTAACTT GTGTTTCTTG 
CTTACCCTGC CCTTCTGGGC TCATGCTGGG GGCGATCCCA TGTGTAAAAT TCTCATTGGA 
CTGTACTTCG TGGGCCTGTA CAGTGAGACA TTTTTCAATT GCCTTCTGAC TGTGCAAAGG 
TACCTAGTGT TTTTGCACAA GGGAAACTTT TTCTCAGCCA GGAGGAGGGT GCCCTGTGGC 
ATCATTACAA GTGTCCTGGC ATGGGTAACA GCCATTCTGG CCACTTTGCC TGAATTCGTG 
GTTTATAAAC CTCAGATGGA AGACCAGAAA TACAAGTGTG CATTTAGCAG AACTCCCTTC 
CTGCCAGCTG ATGAGACATT CTGGAAGCAT TTTCTGACTT TAAAAATGAA CATTTCGGTT 
CTTGTCCTCC CCCTATTTAT TTTTACATTT CTCTATGTGC AAATGAGAAA AACACTAAGG 
TTCAGGGAGC AGAGGTATAG CCTTTTCAAG CTTGTTTTTG CCATAATGGT AGTCTTCCTT 
CTGATGTGGG CGCCCTACAA TATTGCATTT TTCCTGTCCA CTTTCAAAGA ACACTTCTCC 
CTGAGTGACT GCAAGAGCAG CTACAATCTG GACAAAAGTG TTCACATCAC TAAACTCATC 
GCCACCACCC ACTGCTGCAT CAACCCTCTC CTGTATGCGT TTCTTGATGG GACATTTAGC 
AAATACCTCT GCCGCTGTTT CCATCTGCGT AGTAACACCC CACTTCAACC CAGGGGGCAG 
TCTGCACAAG GCACATCGAG GGAAGAACCT GACCATTCCA CCGAAGTGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001124382.1
CDS	57..1127
Translation	MIYTRFLKGSLKMANYTLAPEDEYDVLIEGELESDEAEQCDKYDAQALSAQLVPSLCSAVFVIGVLDNLLVVLILVKYKGLKRVENIYLLNLAVSNLCFLLTLPFWAHAGGDPMCKILIGLYFVGLYSETFFNCLLTVQRYLVFLHKGNFFSARRRVPCGIITSVLAWVTAILATLPEFVVYKPQMEDQKYKCAFSRTPFLPADETFWKHFLTLKMNISVLVLPLFIFTFLYVQMRKTLRFREQRYSLFKLVFAIMVVFLLMWAPYNIAFFLSTFKEHFSLSDCKSSYNLDKSVHITKLIATTHCCINPLLYAFLDGTFSKYLCRCFHLRSNTPLQPRGQSAQGTSREEPDHSTEV

Target ORF information:

RefSeq Version	NM_001130910.2
Organism	Homo sapiens(human)
Definition	Homo sapiens C-C motif chemokine receptor like 2 (CCRL2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001130910.2

ORF Insert Sequence:

ATGATCTACA CCCGTTTCTT AAAAGGCAGT CTGAAGATGG CCAATTACAC GCTGGCACCA 
GAGGATGAAT ATGATGTCCT CATAGAAGGT GAACTGGAGA GCGATGAGGC AGAGCAATGT 
GACAAGTATG ACGCCCAGGC ACTCTCAGCC CAGCTGGTGC CATCACTCTG CTCTGCTGTG 
TTTGTGATCG GTGTCCTGGA CAATCTCCTG GTTGTGCTTA TCCTGGTAAA ATATAAAGGA 
CTCAAACGCG TGGAAAATAT CTATCTTCTA AACTTGGCAG TTTCTAACTT GTGTTTCTTG 
CTTACCCTGC CCTTCTGGGC TCATGCTGGG GGCGATCCCA TGTGTAAAAT TCTCATTGGA 
CTGTACTTCG TGGGCCTGTA CAGTGAGACA TTTTTCAATT GCCTTCTGAC TGTGCAAAGG 
TACCTAGTGT TTTTGCACAA GGGAAACTTT TTCTCAGCCA GGAGGAGGGT GCCCTGTGGC 
ATCATTACAA GTGTCCTGGC ATGGGTAACA GCCATTCTGG CCACTTTGCC TGAATTCGTG 
GTTTATAAAC CTCAGATGGA AGACCAGAAA TACAAGTGTG CATTTAGCAG AACTCCCTTC 
CTGCCAGCTG ATGAGACATT CTGGAAGCAT TTTCTGACTT TAAAAATGAA CATTTCGGTT 
CTTGTCCTCC CCCTATTTAT TTTTACATTT CTCTATGTGC AAATGAGAAA AACACTAAGG 
TTCAGGGAGC AGAGGTATAG CCTTTTCAAG CTTGTTTTTG CCATAATGGT AGTCTTCCTT 
CTGATGTGGG CGCCCTACAA TATTGCATTT TTCCTGTCCA CTTTCAAAGA ACACTTCTCC 
CTGAGTGACT GCAAGAGCAG CTACAATCTG GACAAAAGTG TTCACATCAC TAAACTCATC 
GCCACCACCC ACTGCTGCAT CAACCCTCTC CTGTATGCGT TTCTTGATGG GACATTTAGC 
AAATACCTCT GCCGCTGTTT CCATCTGCGT AGTAACACCC CACTTCAACC CAGGGGGCAG 
TCTGCACAAG GCACATCGAG GGAAGAACCT GACCATTCCA CCGAAGTGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CCRL2 ( NM_001130910.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001124382.1 Homo sapiens C-C motif chemokine receptor like 2 (CCRL2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu07091
Clone ID Related Accession (Same CDS sequence)	NM_001130910.2 , NM_001130910.1
Accession Version	NM_001130910.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1071bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-23
Organism	Homo sapiens(human)
Product	C-C chemokine receptor-like 2 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK296673.1, AF015524.1 and AC098613.2. Transcript Variant: This variant (2) differs in the 5' UTR and coding region, compared to variant 1, resulting in a longer isoform (2) that has a distinct N-terminus, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF015524.1, AK296673.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGATCTACA CCCGTTTCTT AAAAGGCAGT CTGAAGATGG CCAATTACAC GCTGGCACCA 
GAGGATGAAT ATGATGTCCT CATAGAAGGT GAACTGGAGA GCGATGAGGC AGAGCAATGT 
GACAAGTATG ACGCCCAGGC ACTCTCAGCC CAGCTGGTGC CATCACTCTG CTCTGCTGTG 
TTTGTGATCG GTGTCCTGGA CAATCTCCTG GTTGTGCTTA TCCTGGTAAA ATATAAAGGA 
CTCAAACGCG TGGAAAATAT CTATCTTCTA AACTTGGCAG TTTCTAACTT GTGTTTCTTG 
CTTACCCTGC CCTTCTGGGC TCATGCTGGG GGCGATCCCA TGTGTAAAAT TCTCATTGGA 
CTGTACTTCG TGGGCCTGTA CAGTGAGACA TTTTTCAATT GCCTTCTGAC TGTGCAAAGG 
TACCTAGTGT TTTTGCACAA GGGAAACTTT TTCTCAGCCA GGAGGAGGGT GCCCTGTGGC 
ATCATTACAA GTGTCCTGGC ATGGGTAACA GCCATTCTGG CCACTTTGCC TGAATTCGTG 
GTTTATAAAC CTCAGATGGA AGACCAGAAA TACAAGTGTG CATTTAGCAG AACTCCCTTC 
CTGCCAGCTG ATGAGACATT CTGGAAGCAT TTTCTGACTT TAAAAATGAA CATTTCGGTT 
CTTGTCCTCC CCCTATTTAT TTTTACATTT CTCTATGTGC AAATGAGAAA AACACTAAGG 
TTCAGGGAGC AGAGGTATAG CCTTTTCAAG CTTGTTTTTG CCATAATGGT AGTCTTCCTT 
CTGATGTGGG CGCCCTACAA TATTGCATTT TTCCTGTCCA CTTTCAAAGA ACACTTCTCC 
CTGAGTGACT GCAAGAGCAG CTACAATCTG GACAAAAGTG TTCACATCAC TAAACTCATC 
GCCACCACCC ACTGCTGCAT CAACCCTCTC CTGTATGCGT TTCTTGATGG GACATTTAGC 
AAATACCTCT GCCGCTGTTT CCATCTGCGT AGTAACACCC CACTTCAACC CAGGGGGCAG 
TCTGCACAAG GCACATCGAG GGAAGAACCT GACCATTCCA CCGAAGTGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001124382.1
CDS	114..1184
Translation	MIYTRFLKGSLKMANYTLAPEDEYDVLIEGELESDEAEQCDKYDAQALSAQLVPSLCSAVFVIGVLDNLLVVLILVKYKGLKRVENIYLLNLAVSNLCFLLTLPFWAHAGGDPMCKILIGLYFVGLYSETFFNCLLTVQRYLVFLHKGNFFSARRRVPCGIITSVLAWVTAILATLPEFVVYKPQMEDQKYKCAFSRTPFLPADETFWKHFLTLKMNISVLVLPLFIFTFLYVQMRKTLRFREQRYSLFKLVFAIMVVFLLMWAPYNIAFFLSTFKEHFSLSDCKSSYNLDKSVHITKLIATTHCCINPLLYAFLDGTFSKYLCRCFHLRSNTPLQPRGQSAQGTSREEPDHSTEV

Target ORF information:

RefSeq Version	NM_001130910.1
Organism	Homo sapiens(human)
Definition	Homo sapiens C-C motif chemokine receptor like 2 (CCRL2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001130910.1

ORF Insert Sequence:

ATGATCTACA CCCGTTTCTT AAAAGGCAGT CTGAAGATGG CCAATTACAC GCTGGCACCA 
GAGGATGAAT ATGATGTCCT CATAGAAGGT GAACTGGAGA GCGATGAGGC AGAGCAATGT 
GACAAGTATG ACGCCCAGGC ACTCTCAGCC CAGCTGGTGC CATCACTCTG CTCTGCTGTG 
TTTGTGATCG GTGTCCTGGA CAATCTCCTG GTTGTGCTTA TCCTGGTAAA ATATAAAGGA 
CTCAAACGCG TGGAAAATAT CTATCTTCTA AACTTGGCAG TTTCTAACTT GTGTTTCTTG 
CTTACCCTGC CCTTCTGGGC TCATGCTGGG GGCGATCCCA TGTGTAAAAT TCTCATTGGA 
CTGTACTTCG TGGGCCTGTA CAGTGAGACA TTTTTCAATT GCCTTCTGAC TGTGCAAAGG 
TACCTAGTGT TTTTGCACAA GGGAAACTTT TTCTCAGCCA GGAGGAGGGT GCCCTGTGGC 
ATCATTACAA GTGTCCTGGC ATGGGTAACA GCCATTCTGG CCACTTTGCC TGAATTCGTG 
GTTTATAAAC CTCAGATGGA AGACCAGAAA TACAAGTGTG CATTTAGCAG AACTCCCTTC 
CTGCCAGCTG ATGAGACATT CTGGAAGCAT TTTCTGACTT TAAAAATGAA CATTTCGGTT 
CTTGTCCTCC CCCTATTTAT TTTTACATTT CTCTATGTGC AAATGAGAAA AACACTAAGG 
TTCAGGGAGC AGAGGTATAG CCTTTTCAAG CTTGTTTTTG CCATAATGGT AGTCTTCCTT 
CTGATGTGGG CGCCCTACAA TATTGCATTT TTCCTGTCCA CTTTCAAAGA ACACTTCTCC 
CTGAGTGACT GCAAGAGCAG CTACAATCTG GACAAAAGTG TTCACATCAC TAAACTCATC 
GCCACCACCC ACTGCTGCAT CAACCCTCTC CTGTATGCGT TTCTTGATGG GACATTTAGC 
AAATACCTCT GCCGCTGTTT CCATCTGCGT AGTAACACCC CACTTCAACC CAGGGGGCAG 
TCTGCACAAG GCACATCGAG GGAAGAACCT GACCATTCCA CCGAAGTGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CCRL2 ( NM_003965.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_003956.2 Homo sapiens C-C motif chemokine receptor like 2 (CCRL2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu29384
Clone ID Related Accession (Same CDS sequence)	XM_017007436.1 , XM_011534209.1 , XM_011534208.1 , NM_003965.4 , NM_003965.5
Accession Version	NM_003965.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1035bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-09-30
Organism	Homo sapiens(human)
Product	C-C chemokine receptor-like 2 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF015525.1 and BC071682.1. On or before Mar 27, 2009 this sequence version replaced NM_001097632.1, XM_001717282.1, NM_003965.3. Transcript Variant: This variant (1) represents the shortest transcript but encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF015525.1, SRR1163657.260326.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCAATT ACACGCTGGC ACCAGAGGAT GAATATGATG TCCTCATAGA AGGTGAACTG 
GAGAGCGATG AGGCAGAGCA ATGTGACAAG TATGACGCCC AGGCACTCTC AGCCCAGCTG 
GTGCCATCAC TCTGCTCTGC TGTGTTTGTG ATCGGTGTCC TGGACAATCT CCTGGTTGTG 
CTTATCCTGG TAAAATATAA AGGACTCAAA CGCGTGGAAA ATATCTATCT TCTAAACTTG 
GCAGTTTCTA ACTTGTGTTT CTTGCTTACC CTGCCCTTCT GGGCTCATGC TGGGGGCGAT 
CCCATGTGTA AAATTCTCAT TGGACTGTAC TTCGTGGGCC TGTACAGTGA GACATTTTTC 
AATTGCCTTC TGACTGTGCA AAGGTACCTA GTGTTTTTGC ACAAGGGAAA CTTTTTCTCA 
GCCAGGAGGA GGGTGCCCTG TGGCATCATT ACAAGTGTCC TGGCATGGGT AACAGCCATT 
CTGGCCACTT TGCCTGAATT CGTGGTTTAT AAACCTCAGA TGGAAGACCA GAAATACAAG 
TGTGCATTTA GCAGAACTCC CTTCCTGCCA GCTGATGAGA CATTCTGGAA GCATTTTCTG 
ACTTTAAAAA TGAACATTTC GGTTCTTGTC CTCCCCCTAT TTATTTTTAC ATTTCTCTAT 
GTGCAAATGA GAAAAACACT AAGGTTCAGG GAGCAGAGGT ATAGCCTTTT CAAGCTTGTT 
TTTGCCATAA TGGTAGTCTT CCTTCTGATG TGGGCGCCCT ACAATATTGC ATTTTTCCTG 
TCCACTTTCA AAGAACACTT CTCCCTGAGT GACTGCAAGA GCAGCTACAA TCTGGACAAA 
AGTGTTCACA TCACTAAACT CATCGCCACC ACCCACTGCT GCATCAACCC TCTCCTGTAT 
GCGTTTCTTG ATGGGACATT TAGCAAATAC CTCTGCCGCT GTTTCCATCT GCGTAGTAAC 
ACCCCACTTC AACCCAGGGG GCAGTCTGCA CAAGGCACAT CGAGGGAAGA ACCTGACCAT 
TCCACCGAAG TGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_003956.2
CDS	286..1320
Translation	MANYTLAPEDEYDVLIEGELESDEAEQCDKYDAQALSAQLVPSLCSAVFVIGVLDNLLVVLILVKYKGLKRVENIYLLNLAVSNLCFLLTLPFWAHAGGDPMCKILIGLYFVGLYSETFFNCLLTVQRYLVFLHKGNFFSARRRVPCGIITSVLAWVTAILATLPEFVVYKPQMEDQKYKCAFSRTPFLPADETFWKHFLTLKMNISVLVLPLFIFTFLYVQMRKTLRFREQRYSLFKLVFAIMVVFLLMWAPYNIAFFLSTFKEHFSLSDCKSSYNLDKSVHITKLIATTHCCINPLLYAFLDGTFSKYLCRCFHLRSNTPLQPRGQSAQGTSREEPDHSTEV

Target ORF information:

RefSeq Version	NM_003965.4
Organism	Homo sapiens(human)
Definition	Homo sapiens C-C motif chemokine receptor like 2 (CCRL2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_003965.4

ORF Insert Sequence:

ATGGCCAATT ACACGCTGGC ACCAGAGGAT GAATATGATG TCCTCATAGA AGGTGAACTG 
GAGAGCGATG AGGCAGAGCA ATGTGACAAG TATGACGCCC AGGCACTCTC AGCCCAGCTG 
GTGCCATCAC TCTGCTCTGC TGTGTTTGTG ATCGGTGTCC TGGACAATCT CCTGGTTGTG 
CTTATCCTGG TAAAATATAA AGGACTCAAA CGCGTGGAAA ATATCTATCT TCTAAACTTG 
GCAGTTTCTA ACTTGTGTTT CTTGCTTACC CTGCCCTTCT GGGCTCATGC TGGGGGCGAT 
CCCATGTGTA AAATTCTCAT TGGACTGTAC TTCGTGGGCC TGTACAGTGA GACATTTTTC 
AATTGCCTTC TGACTGTGCA AAGGTACCTA GTGTTTTTGC ACAAGGGAAA CTTTTTCTCA 
GCCAGGAGGA GGGTGCCCTG TGGCATCATT ACAAGTGTCC TGGCATGGGT AACAGCCATT 
CTGGCCACTT TGCCTGAATT CGTGGTTTAT AAACCTCAGA TGGAAGACCA GAAATACAAG 
TGTGCATTTA GCAGAACTCC CTTCCTGCCA GCTGATGAGA CATTCTGGAA GCATTTTCTG 
ACTTTAAAAA TGAACATTTC GGTTCTTGTC CTCCCCCTAT TTATTTTTAC ATTTCTCTAT 
GTGCAAATGA GAAAAACACT AAGGTTCAGG GAGCAGAGGT ATAGCCTTTT CAAGCTTGTT 
TTTGCCATAA TGGTAGTCTT CCTTCTGATG TGGGCGCCCT ACAATATTGC ATTTTTCCTG 
TCCACTTTCA AAGAACACTT CTCCCTGAGT GACTGCAAGA GCAGCTACAA TCTGGACAAA 
AGTGTTCACA TCACTAAACT CATCGCCACC ACCCACTGCT GCATCAACCC TCTCCTGTAT 
GCGTTTCTTG ATGGGACATT TAGCAAATAC CTCTGCCGCT GTTTCCATCT GCGTAGTAAC 
ACCCCACTTC AACCCAGGGG GCAGTCTGCA CAAGGCACAT CGAGGGAAGA ACCTGACCAT 
TCCACCGAAG TGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CCRL2 ( NM_003965.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_003956.2 Homo sapiens C-C motif chemokine receptor like 2 (CCRL2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu29384
Clone ID Related Accession (Same CDS sequence)	XM_017007436.1 , XM_011534209.1 , XM_011534208.1 , NM_003965.4 , NM_003965.5
Accession Version	NM_003965.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1035bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-01
Organism	Homo sapiens(human)
Product	C-C chemokine receptor-like 2 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF015525.1 and BC071682.1. On Nov 22, 2018 this sequence version replaced NM_003965.4. Transcript Variant: This variant (1) represents the shortest transcript but encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF015525.1, SRR5189661.132309.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000399036.4/ ENSP00000381994.3 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCCAATT ACACGCTGGC ACCAGAGGAT GAATATGATG TCCTCATAGA AGGTGAACTG 
GAGAGCGATG AGGCAGAGCA ATGTGACAAG TATGACGCCC AGGCACTCTC AGCCCAGCTG 
GTGCCATCAC TCTGCTCTGC TGTGTTTGTG ATCGGTGTCC TGGACAATCT CCTGGTTGTG 
CTTATCCTGG TAAAATATAA AGGACTCAAA CGCGTGGAAA ATATCTATCT TCTAAACTTG 
GCAGTTTCTA ACTTGTGTTT CTTGCTTACC CTGCCCTTCT GGGCTCATGC TGGGGGCGAT 
CCCATGTGTA AAATTCTCAT TGGACTGTAC TTCGTGGGCC TGTACAGTGA GACATTTTTC 
AATTGCCTTC TGACTGTGCA AAGGTACCTA GTGTTTTTGC ACAAGGGAAA CTTTTTCTCA 
GCCAGGAGGA GGGTGCCCTG TGGCATCATT ACAAGTGTCC TGGCATGGGT AACAGCCATT 
CTGGCCACTT TGCCTGAATT CGTGGTTTAT AAACCTCAGA TGGAAGACCA GAAATACAAG 
TGTGCATTTA GCAGAACTCC CTTCCTGCCA GCTGATGAGA CATTCTGGAA GCATTTTCTG 
ACTTTAAAAA TGAACATTTC GGTTCTTGTC CTCCCCCTAT TTATTTTTAC ATTTCTCTAT 
GTGCAAATGA GAAAAACACT AAGGTTCAGG GAGCAGAGGT ATAGCCTTTT CAAGCTTGTT 
TTTGCCATAA TGGTAGTCTT CCTTCTGATG TGGGCGCCCT ACAATATTGC ATTTTTCCTG 
TCCACTTTCA AAGAACACTT CTCCCTGAGT GACTGCAAGA GCAGCTACAA TCTGGACAAA 
AGTGTTCACA TCACTAAACT CATCGCCACC ACCCACTGCT GCATCAACCC TCTCCTGTAT 
GCGTTTCTTG ATGGGACATT TAGCAAATAC CTCTGCCGCT GTTTCCATCT GCGTAGTAAC 
ACCCCACTTC AACCCAGGGG GCAGTCTGCA CAAGGCACAT CGAGGGAAGA ACCTGACCAT 
TCCACCGAAG TGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_003956.2
CDS	257..1291
Translation	MANYTLAPEDEYDVLIEGELESDEAEQCDKYDAQALSAQLVPSLCSAVFVIGVLDNLLVVLILVKYKGLKRVENIYLLNLAVSNLCFLLTLPFWAHAGGDPMCKILIGLYFVGLYSETFFNCLLTVQRYLVFLHKGNFFSARRRVPCGIITSVLAWVTAILATLPEFVVYKPQMEDQKYKCAFSRTPFLPADETFWKHFLTLKMNISVLVLPLFIFTFLYVQMRKTLRFREQRYSLFKLVFAIMVVFLLMWAPYNIAFFLSTFKEHFSLSDCKSSYNLDKSVHITKLIATTHCCINPLLYAFLDGTFSKYLCRCFHLRSNTPLQPRGQSAQGTSREEPDHSTEV

Target ORF information:

RefSeq Version	NM_003965.5
Organism	Homo sapiens(human)
Definition	Homo sapiens C-C motif chemokine receptor like 2 (CCRL2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_003965.5

ORF Insert Sequence:

ATGGCCAATT ACACGCTGGC ACCAGAGGAT GAATATGATG TCCTCATAGA AGGTGAACTG 
GAGAGCGATG AGGCAGAGCA ATGTGACAAG TATGACGCCC AGGCACTCTC AGCCCAGCTG 
GTGCCATCAC TCTGCTCTGC TGTGTTTGTG ATCGGTGTCC TGGACAATCT CCTGGTTGTG 
CTTATCCTGG TAAAATATAA AGGACTCAAA CGCGTGGAAA ATATCTATCT TCTAAACTTG 
GCAGTTTCTA ACTTGTGTTT CTTGCTTACC CTGCCCTTCT GGGCTCATGC TGGGGGCGAT 
CCCATGTGTA AAATTCTCAT TGGACTGTAC TTCGTGGGCC TGTACAGTGA GACATTTTTC 
AATTGCCTTC TGACTGTGCA AAGGTACCTA GTGTTTTTGC ACAAGGGAAA CTTTTTCTCA 
GCCAGGAGGA GGGTGCCCTG TGGCATCATT ACAAGTGTCC TGGCATGGGT AACAGCCATT 
CTGGCCACTT TGCCTGAATT CGTGGTTTAT AAACCTCAGA TGGAAGACCA GAAATACAAG 
TGTGCATTTA GCAGAACTCC CTTCCTGCCA GCTGATGAGA CATTCTGGAA GCATTTTCTG 
ACTTTAAAAA TGAACATTTC GGTTCTTGTC CTCCCCCTAT TTATTTTTAC ATTTCTCTAT 
GTGCAAATGA GAAAAACACT AAGGTTCAGG GAGCAGAGGT ATAGCCTTTT CAAGCTTGTT 
TTTGCCATAA TGGTAGTCTT CCTTCTGATG TGGGCGCCCT ACAATATTGC ATTTTTCCTG 
TCCACTTTCA AAGAACACTT CTCCCTGAGT GACTGCAAGA GCAGCTACAA TCTGGACAAA 
AGTGTTCACA TCACTAAACT CATCGCCACC ACCCACTGCT GCATCAACCC TCTCCTGTAT 
GCGTTTCTTG ATGGGACATT TAGCAAATAC CTCTGCCGCT GTTTCCATCT GCGTAGTAAC 
ACCCCACTTC AACCCAGGGG GCAGTCTGCA CAAGGCACAT CGAGGGAAGA ACCTGACCAT 
TCCACCGAAG TGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CCRL2 ( XM_017007436.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016862925.1 Homo sapiens C-C motif chemokine receptor like 2 (CCRL2), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu29384
Clone ID Related Accession (Same CDS sequence)	XM_017007436.1 , XM_011534209.1 , XM_011534208.1 , NM_003965.4 , NM_003965.5
Accession Version	XM_017007436.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1035bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	C-C chemokine receptor-like 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000003.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCCAATT ACACGCTGGC ACCAGAGGAT GAATATGATG TCCTCATAGA AGGTGAACTG 
GAGAGCGATG AGGCAGAGCA ATGTGACAAG TATGACGCCC AGGCACTCTC AGCCCAGCTG 
GTGCCATCAC TCTGCTCTGC TGTGTTTGTG ATCGGTGTCC TGGACAATCT CCTGGTTGTG 
CTTATCCTGG TAAAATATAA AGGACTCAAA CGCGTGGAAA ATATCTATCT TCTAAACTTG 
GCAGTTTCTA ACTTGTGTTT CTTGCTTACC CTGCCCTTCT GGGCTCATGC TGGGGGCGAT 
CCCATGTGTA AAATTCTCAT TGGACTGTAC TTCGTGGGCC TGTACAGTGA GACATTTTTC 
AATTGCCTTC TGACTGTGCA AAGGTACCTA GTGTTTTTGC ACAAGGGAAA CTTTTTCTCA 
GCCAGGAGGA GGGTGCCCTG TGGCATCATT ACAAGTGTCC TGGCATGGGT AACAGCCATT 
CTGGCCACTT TGCCTGAATT CGTGGTTTAT AAACCTCAGA TGGAAGACCA GAAATACAAG 
TGTGCATTTA GCAGAACTCC CTTCCTGCCA GCTGATGAGA CATTCTGGAA GCATTTTCTG 
ACTTTAAAAA TGAACATTTC GGTTCTTGTC CTCCCCCTAT TTATTTTTAC ATTTCTCTAT 
GTGCAAATGA GAAAAACACT AAGGTTCAGG GAGCAGAGGT ATAGCCTTTT CAAGCTTGTT 
TTTGCCATAA TGGTAGTCTT CCTTCTGATG TGGGCGCCCT ACAATATTGC ATTTTTCCTG 
TCCACTTTCA AAGAACACTT CTCCCTGAGT GACTGCAAGA GCAGCTACAA TCTGGACAAA 
AGTGTTCACA TCACTAAACT CATCGCCACC ACCCACTGCT GCATCAACCC TCTCCTGTAT 
GCGTTTCTTG ATGGGACATT TAGCAAATAC CTCTGCCGCT GTTTCCATCT GCGTAGTAAC 
ACCCCACTTC AACCCAGGGG GCAGTCTGCA CAAGGCACAT CGAGGGAAGA ACCTGACCAT 
TCCACCGAAG TGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016862925.1
CDS	146..1180
Translation	MANYTLAPEDEYDVLIEGELESDEAEQCDKYDAQALSAQLVPSLCSAVFVIGVLDNLLVVLILVKYKGLKRVENIYLLNLAVSNLCFLLTLPFWAHAGGDPMCKILIGLYFVGLYSETFFNCLLTVQRYLVFLHKGNFFSARRRVPCGIITSVLAWVTAILATLPEFVVYKPQMEDQKYKCAFSRTPFLPADETFWKHFLTLKMNISVLVLPLFIFTFLYVQMRKTLRFREQRYSLFKLVFAIMVVFLLMWAPYNIAFFLSTFKEHFSLSDCKSSYNLDKSVHITKLIATTHCCINPLLYAFLDGTFSKYLCRCFHLRSNTPLQPRGQSAQGTSREEPDHSTEV

Target ORF information:

RefSeq Version	XM_017007436.1
Organism	Homo sapiens(human)
Definition	Homo sapiens C-C motif chemokine receptor like 2 (CCRL2), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017007436.1

ORF Insert Sequence:

ATGGCCAATT ACACGCTGGC ACCAGAGGAT GAATATGATG TCCTCATAGA AGGTGAACTG 
GAGAGCGATG AGGCAGAGCA ATGTGACAAG TATGACGCCC AGGCACTCTC AGCCCAGCTG 
GTGCCATCAC TCTGCTCTGC TGTGTTTGTG ATCGGTGTCC TGGACAATCT CCTGGTTGTG 
CTTATCCTGG TAAAATATAA AGGACTCAAA CGCGTGGAAA ATATCTATCT TCTAAACTTG 
GCAGTTTCTA ACTTGTGTTT CTTGCTTACC CTGCCCTTCT GGGCTCATGC TGGGGGCGAT 
CCCATGTGTA AAATTCTCAT TGGACTGTAC TTCGTGGGCC TGTACAGTGA GACATTTTTC 
AATTGCCTTC TGACTGTGCA AAGGTACCTA GTGTTTTTGC ACAAGGGAAA CTTTTTCTCA 
GCCAGGAGGA GGGTGCCCTG TGGCATCATT ACAAGTGTCC TGGCATGGGT AACAGCCATT 
CTGGCCACTT TGCCTGAATT CGTGGTTTAT AAACCTCAGA TGGAAGACCA GAAATACAAG 
TGTGCATTTA GCAGAACTCC CTTCCTGCCA GCTGATGAGA CATTCTGGAA GCATTTTCTG 
ACTTTAAAAA TGAACATTTC GGTTCTTGTC CTCCCCCTAT TTATTTTTAC ATTTCTCTAT 
GTGCAAATGA GAAAAACACT AAGGTTCAGG GAGCAGAGGT ATAGCCTTTT CAAGCTTGTT 
TTTGCCATAA TGGTAGTCTT CCTTCTGATG TGGGCGCCCT ACAATATTGC ATTTTTCCTG 
TCCACTTTCA AAGAACACTT CTCCCTGAGT GACTGCAAGA GCAGCTACAA TCTGGACAAA 
AGTGTTCACA TCACTAAACT CATCGCCACC ACCCACTGCT GCATCAACCC TCTCCTGTAT 
GCGTTTCTTG ATGGGACATT TAGCAAATAC CTCTGCCGCT GTTTCCATCT GCGTAGTAAC 
ACCCCACTTC AACCCAGGGG GCAGTCTGCA CAAGGCACAT CGAGGGAAGA ACCTGACCAT 
TCCACCGAAG TGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CCRL2 ( XM_011534209.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011532511.1 Homo sapiens C-C motif chemokine receptor like 2 (CCRL2), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu29384
Clone ID Related Accession (Same CDS sequence)	XM_017007436.1 , XM_011534209.1 , XM_011534208.1 , NM_003965.4 , NM_003965.5
Accession Version	XM_011534209.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1035bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	C-C chemokine receptor-like 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000003.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCCAATT ACACGCTGGC ACCAGAGGAT GAATATGATG TCCTCATAGA AGGTGAACTG 
GAGAGCGATG AGGCAGAGCA ATGTGACAAG TATGACGCCC AGGCACTCTC AGCCCAGCTG 
GTGCCATCAC TCTGCTCTGC TGTGTTTGTG ATCGGTGTCC TGGACAATCT CCTGGTTGTG 
CTTATCCTGG TAAAATATAA AGGACTCAAA CGCGTGGAAA ATATCTATCT TCTAAACTTG 
GCAGTTTCTA ACTTGTGTTT CTTGCTTACC CTGCCCTTCT GGGCTCATGC TGGGGGCGAT 
CCCATGTGTA AAATTCTCAT TGGACTGTAC TTCGTGGGCC TGTACAGTGA GACATTTTTC 
AATTGCCTTC TGACTGTGCA AAGGTACCTA GTGTTTTTGC ACAAGGGAAA CTTTTTCTCA 
GCCAGGAGGA GGGTGCCCTG TGGCATCATT ACAAGTGTCC TGGCATGGGT AACAGCCATT 
CTGGCCACTT TGCCTGAATT CGTGGTTTAT AAACCTCAGA TGGAAGACCA GAAATACAAG 
TGTGCATTTA GCAGAACTCC CTTCCTGCCA GCTGATGAGA CATTCTGGAA GCATTTTCTG 
ACTTTAAAAA TGAACATTTC GGTTCTTGTC CTCCCCCTAT TTATTTTTAC ATTTCTCTAT 
GTGCAAATGA GAAAAACACT AAGGTTCAGG GAGCAGAGGT ATAGCCTTTT CAAGCTTGTT 
TTTGCCATAA TGGTAGTCTT CCTTCTGATG TGGGCGCCCT ACAATATTGC ATTTTTCCTG 
TCCACTTTCA AAGAACACTT CTCCCTGAGT GACTGCAAGA GCAGCTACAA TCTGGACAAA 
AGTGTTCACA TCACTAAACT CATCGCCACC ACCCACTGCT GCATCAACCC TCTCCTGTAT 
GCGTTTCTTG ATGGGACATT TAGCAAATAC CTCTGCCGCT GTTTCCATCT GCGTAGTAAC 
ACCCCACTTC AACCCAGGGG GCAGTCTGCA CAAGGCACAT CGAGGGAAGA ACCTGACCAT 
TCCACCGAAG TGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011532511.1
CDS	153..1187
Translation	MANYTLAPEDEYDVLIEGELESDEAEQCDKYDAQALSAQLVPSLCSAVFVIGVLDNLLVVLILVKYKGLKRVENIYLLNLAVSNLCFLLTLPFWAHAGGDPMCKILIGLYFVGLYSETFFNCLLTVQRYLVFLHKGNFFSARRRVPCGIITSVLAWVTAILATLPEFVVYKPQMEDQKYKCAFSRTPFLPADETFWKHFLTLKMNISVLVLPLFIFTFLYVQMRKTLRFREQRYSLFKLVFAIMVVFLLMWAPYNIAFFLSTFKEHFSLSDCKSSYNLDKSVHITKLIATTHCCINPLLYAFLDGTFSKYLCRCFHLRSNTPLQPRGQSAQGTSREEPDHSTEV

Target ORF information:

RefSeq Version	XM_011534209.1
Organism	Homo sapiens(human)
Definition	Homo sapiens C-C motif chemokine receptor like 2 (CCRL2), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011534209.1

ORF Insert Sequence:

ATGGCCAATT ACACGCTGGC ACCAGAGGAT GAATATGATG TCCTCATAGA AGGTGAACTG 
GAGAGCGATG AGGCAGAGCA ATGTGACAAG TATGACGCCC AGGCACTCTC AGCCCAGCTG 
GTGCCATCAC TCTGCTCTGC TGTGTTTGTG ATCGGTGTCC TGGACAATCT CCTGGTTGTG 
CTTATCCTGG TAAAATATAA AGGACTCAAA CGCGTGGAAA ATATCTATCT TCTAAACTTG 
GCAGTTTCTA ACTTGTGTTT CTTGCTTACC CTGCCCTTCT GGGCTCATGC TGGGGGCGAT 
CCCATGTGTA AAATTCTCAT TGGACTGTAC TTCGTGGGCC TGTACAGTGA GACATTTTTC 
AATTGCCTTC TGACTGTGCA AAGGTACCTA GTGTTTTTGC ACAAGGGAAA CTTTTTCTCA 
GCCAGGAGGA GGGTGCCCTG TGGCATCATT ACAAGTGTCC TGGCATGGGT AACAGCCATT 
CTGGCCACTT TGCCTGAATT CGTGGTTTAT AAACCTCAGA TGGAAGACCA GAAATACAAG 
TGTGCATTTA GCAGAACTCC CTTCCTGCCA GCTGATGAGA CATTCTGGAA GCATTTTCTG 
ACTTTAAAAA TGAACATTTC GGTTCTTGTC CTCCCCCTAT TTATTTTTAC ATTTCTCTAT 
GTGCAAATGA GAAAAACACT AAGGTTCAGG GAGCAGAGGT ATAGCCTTTT CAAGCTTGTT 
TTTGCCATAA TGGTAGTCTT CCTTCTGATG TGGGCGCCCT ACAATATTGC ATTTTTCCTG 
TCCACTTTCA AAGAACACTT CTCCCTGAGT GACTGCAAGA GCAGCTACAA TCTGGACAAA 
AGTGTTCACA TCACTAAACT CATCGCCACC ACCCACTGCT GCATCAACCC TCTCCTGTAT 
GCGTTTCTTG ATGGGACATT TAGCAAATAC CTCTGCCGCT GTTTCCATCT GCGTAGTAAC 
ACCCCACTTC AACCCAGGGG GCAGTCTGCA CAAGGCACAT CGAGGGAAGA ACCTGACCAT 
TCCACCGAAG TGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CCRL2 ( XM_011534208.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011532510.1 Homo sapiens C-C motif chemokine receptor like 2 (CCRL2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu29384
Clone ID Related Accession (Same CDS sequence)	XM_017007436.1 , XM_011534209.1 , XM_011534208.1 , NM_003965.4 , NM_003965.5
Accession Version	XM_011534208.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1035bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	C-C chemokine receptor-like 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000003.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCCAATT ACACGCTGGC ACCAGAGGAT GAATATGATG TCCTCATAGA AGGTGAACTG 
GAGAGCGATG AGGCAGAGCA ATGTGACAAG TATGACGCCC AGGCACTCTC AGCCCAGCTG 
GTGCCATCAC TCTGCTCTGC TGTGTTTGTG ATCGGTGTCC TGGACAATCT CCTGGTTGTG 
CTTATCCTGG TAAAATATAA AGGACTCAAA CGCGTGGAAA ATATCTATCT TCTAAACTTG 
GCAGTTTCTA ACTTGTGTTT CTTGCTTACC CTGCCCTTCT GGGCTCATGC TGGGGGCGAT 
CCCATGTGTA AAATTCTCAT TGGACTGTAC TTCGTGGGCC TGTACAGTGA GACATTTTTC 
AATTGCCTTC TGACTGTGCA AAGGTACCTA GTGTTTTTGC ACAAGGGAAA CTTTTTCTCA 
GCCAGGAGGA GGGTGCCCTG TGGCATCATT ACAAGTGTCC TGGCATGGGT AACAGCCATT 
CTGGCCACTT TGCCTGAATT CGTGGTTTAT AAACCTCAGA TGGAAGACCA GAAATACAAG 
TGTGCATTTA GCAGAACTCC CTTCCTGCCA GCTGATGAGA CATTCTGGAA GCATTTTCTG 
ACTTTAAAAA TGAACATTTC GGTTCTTGTC CTCCCCCTAT TTATTTTTAC ATTTCTCTAT 
GTGCAAATGA GAAAAACACT AAGGTTCAGG GAGCAGAGGT ATAGCCTTTT CAAGCTTGTT 
TTTGCCATAA TGGTAGTCTT CCTTCTGATG TGGGCGCCCT ACAATATTGC ATTTTTCCTG 
TCCACTTTCA AAGAACACTT CTCCCTGAGT GACTGCAAGA GCAGCTACAA TCTGGACAAA 
AGTGTTCACA TCACTAAACT CATCGCCACC ACCCACTGCT GCATCAACCC TCTCCTGTAT 
GCGTTTCTTG ATGGGACATT TAGCAAATAC CTCTGCCGCT GTTTCCATCT GCGTAGTAAC 
ACCCCACTTC AACCCAGGGG GCAGTCTGCA CAAGGCACAT CGAGGGAAGA ACCTGACCAT 
TCCACCGAAG TGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011532510.1
CDS	230..1264
Translation	MANYTLAPEDEYDVLIEGELESDEAEQCDKYDAQALSAQLVPSLCSAVFVIGVLDNLLVVLILVKYKGLKRVENIYLLNLAVSNLCFLLTLPFWAHAGGDPMCKILIGLYFVGLYSETFFNCLLTVQRYLVFLHKGNFFSARRRVPCGIITSVLAWVTAILATLPEFVVYKPQMEDQKYKCAFSRTPFLPADETFWKHFLTLKMNISVLVLPLFIFTFLYVQMRKTLRFREQRYSLFKLVFAIMVVFLLMWAPYNIAFFLSTFKEHFSLSDCKSSYNLDKSVHITKLIATTHCCINPLLYAFLDGTFSKYLCRCFHLRSNTPLQPRGQSAQGTSREEPDHSTEV

Target ORF information:

RefSeq Version	XM_011534208.1
Organism	Homo sapiens(human)
Definition	Homo sapiens C-C motif chemokine receptor like 2 (CCRL2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011534208.1

ORF Insert Sequence:

ATGGCCAATT ACACGCTGGC ACCAGAGGAT GAATATGATG TCCTCATAGA AGGTGAACTG 
GAGAGCGATG AGGCAGAGCA ATGTGACAAG TATGACGCCC AGGCACTCTC AGCCCAGCTG 
GTGCCATCAC TCTGCTCTGC TGTGTTTGTG ATCGGTGTCC TGGACAATCT CCTGGTTGTG 
CTTATCCTGG TAAAATATAA AGGACTCAAA CGCGTGGAAA ATATCTATCT TCTAAACTTG 
GCAGTTTCTA ACTTGTGTTT CTTGCTTACC CTGCCCTTCT GGGCTCATGC TGGGGGCGAT 
CCCATGTGTA AAATTCTCAT TGGACTGTAC TTCGTGGGCC TGTACAGTGA GACATTTTTC 
AATTGCCTTC TGACTGTGCA AAGGTACCTA GTGTTTTTGC ACAAGGGAAA CTTTTTCTCA 
GCCAGGAGGA GGGTGCCCTG TGGCATCATT ACAAGTGTCC TGGCATGGGT AACAGCCATT 
CTGGCCACTT TGCCTGAATT CGTGGTTTAT AAACCTCAGA TGGAAGACCA GAAATACAAG 
TGTGCATTTA GCAGAACTCC CTTCCTGCCA GCTGATGAGA CATTCTGGAA GCATTTTCTG 
ACTTTAAAAA TGAACATTTC GGTTCTTGTC CTCCCCCTAT TTATTTTTAC ATTTCTCTAT 
GTGCAAATGA GAAAAACACT AAGGTTCAGG GAGCAGAGGT ATAGCCTTTT CAAGCTTGTT 
TTTGCCATAA TGGTAGTCTT CCTTCTGATG TGGGCGCCCT ACAATATTGC ATTTTTCCTG 
TCCACTTTCA AAGAACACTT CTCCCTGAGT GACTGCAAGA GCAGCTACAA TCTGGACAAA 
AGTGTTCACA TCACTAAACT CATCGCCACC ACCCACTGCT GCATCAACCC TCTCCTGTAT 
GCGTTTCTTG ATGGGACATT TAGCAAATAC CTCTGCCGCT GTTTCCATCT GCGTAGTAAC 
ACCCCACTTC AACCCAGGGG GCAGTCTGCA CAAGGCACAT CGAGGGAAGA ACCTGACCAT 
TCCACCGAAG TGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Chemokine (CC-motif) receptor-like 2 mRNA is expressed in hepatic stellate cells and is positively associated with characteristics of non-alcoholic steatohepatitis in mice and men.
Experimental and molecular pathology103(1)1-8(2017 08)
Zimny S,Pohl R,Rein-Fischboeck L,Haberl EM,Krautbauer S,Weiss TS,Buechler C

CRAM-A indicates IFN-?-associated inflammatory response in breast cancer.
Molecular immunology68(2 Pt C)692-8(2015 Dec)
Sarmadi P,Tunali G,Esendagli-Yilmaz G,Yilmaz KB,Esendagli G

The human chemokine receptor CCRL2 suppresses chemotaxis and invasion by blocking CCL2-induced phosphorylation of p38 MAPK in human breast cancer cells.
Medical oncology (Northwood, London, England)32(11)254(2015 Nov)
Wang LP,Cao J,Zhang J,Wang BY,Hu XC,Shao ZM,Wang ZH,Ou ZL

Genome-wide association study of CSF levels of 59 alzheimer's disease candidate proteins: significant associations with proteins involved in amyloid processing and inflammation.
PLoS genetics10(10)e1004758(2014 Oct)
Kauwe JS,Bailey MH,Ridge PG,Perry R,Wadsworth ME,Hoyt KL,Staley LA,Karch CM,Harari O,Cruchaga C,Ainscough BJ,Bales K,Pickering EH,Bertelsen S,,Fagan AM,Holtzman DM,Morris JC,Goate AM

Elevated chemokine CC-motif receptor-like 2 (CCRL2) promotes cell migration and invasion in glioblastoma.
Biochemical and biophysical research communications429(3-4)168-72(2012 Dec)
Yin F,Xu Z,Wang Z,Yao H,Shen Z,Yu F,Tang Y,Fu D,Lin S,Lu G,Kung HF,Poon WS,Huang Y,Lin MC

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CCRL2 cDNA ORF clone, Homo sapiens(human)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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