ZCCHC12 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Gene Symbol	ZCCHC12
Entrez Gene ID	170261
Full Name	zinc finger CCHC-type containing 12
Synonyms	PNMA7A,SIZN,SIZN1
General protein information	Preferred Names zinc finger CCHC-type containing 12 Names zinc finger CCHC domain-containing protein 12 paraneoplastic Ma antigen family member 7A smad-interacting zinc finger protein 1 zinc finger, CCHC domain containing 12
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: X Map Location: Xq24
Summary	This gene encodes a downstream effector of bone morphogenetic protein (BMP) signalling. This protein contains a zinc finger domain and functions as a transcriptional coactivator. Variation in this gene may be associated with X-linked cognitive disability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015].
Disorder MIM:	300701

mRNA and Protein(s)

mRNA	Protein	Name
NM_001312891.1	NP_001299820.1	zinc finger CCHC domain-containing protein 12
NM_001312891.2	NP_001299820.1	zinc finger CCHC domain-containing protein 12
NM_173798.3	NP_776159.1	zinc finger CCHC domain-containing protein 12
NM_173798.4	NP_776159.1	zinc finger CCHC domain-containing protein 12

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Zcchc12	NP_082601.1
Rattus norvegicus (Norway rat)	Zcchc12	NP_001014087.1
Canis lupus familiaris (dog)	ZCCHC12	XP_549212.3
Pan troglodytes (chimpanzee)	ZCCHC12	XP_529128.3
Bos taurus (cattle)	ZCCHC12	NP_001069665.1
Homo sapiens (human)	ZCCHC12	NP_776159.1
	ZCCHC12	XP_001099794.2

Gene Ontology
Bibliography

Related articles in PubMed

Architecture of the human interactome defines protein communities and disease networks.
Huttlin EL, Bruckner RJ, Paulo JA, Cannon JR, Ting L, Baltier K, Colby G, Gebreab F, Gygi MP, Parzen H, Szpyt J, Tam S, Zarraga G, Pontano-Vaites L, Swarup S, White AE, Schweppe DK, Rad R, Erickson BK, Obar RA, Guruharsha KG, Li K, Artavanis-Tsakonas S, Gygi SP, Harper JW
Nature545(7655)505-509(2017 05)

ZCCHC12, a novel oncogene in papillary thyroid cancer.
Wang O, Zheng Z, Wang Q, Jin Y, Jin W, Wang Y, Chen E, Zhang X
Journal of cancer research and clinical oncology(2017 Apr)

Widespread macromolecular interaction perturbations in human genetic disorders.
Sahni N, Yi S, Taipale M, Fuxman Bass JI, Coulombe-Huntington J, Yang F, Peng J, Weile J, Karras GI, Wang Y, Kov?cs IA, Kamburov A, Krykbaeva I, Lam MH, Tucker G, Khurana V, Sharma A, Liu YY, Yachie N, Zhong Q, Shen Y, Palagi A, San-Miguel A, Fan C, Balcha D, Dricot A, Jordan DM, Walsh JM, Shah AA, Yang X, Stoyanova AK, Leighton A, Calderwood MA, Jacob Y, Cusick ME, Salehi-Ashtiani K, Whitesell LJ, Sunyaev S, Berger B, Barab?si AL, Charloteaux B, Hill DE, Hao T, Roth FP, Xia Y, Walhout AJM, Lindquist S, Vidal M
Cell161(3)647-660(2015 Apr)

ZCCHC12, a potential molecular marker of papillary thyroid carcinoma: a preliminary study.
Li QL, Chen FJ, Lai R, Guo ZM, Luo R, Yang AK
Medical oncology (Northwood, London, England)29(3)1409-17(2012 Sep)

XLMR candidate mouse gene, Zcchc12 (Sizn1) is a novel marker of Cajal-Retzius cells.
Cho G, Lim Y, Golden JA
Gene expression patterns : GEP11(3-4)216-20(2011 Mar-Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The ZCCHC12 gene may be a novel diagnostic molecular marker of primary papillary thyroid carcinoma
Title: ZCCHC12, a potential molecular marker of papillary thyroid carcinoma: a preliminary study.

ZCCHC12 enhanced the transcriptional activities of activator protein 1 (AP-1) and cAMP response element binding protein (CREB) as a coactivator
Title: Human ZCCHC12 activates AP-1 and CREB signaling as a transcriptional co-activator.

Data indicate that the SIMs in Sizn1 are required for its PML-NB localization and for the full transcriptional co-activation function in BMP signaling.
Title: SUMO interaction motifs in Sizn1 are required for promyelocytic leukemia protein nuclear body localization and for transcriptional activation.

data implicate SIZN1 as a candidate gene for X-linked mental retardation and/or as a neurocognitive functional modifier
Title: Evidence that SIZN1 is a candidate X-linked mental retardation gene.

The following ZCCHC12 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ZCCHC12 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

Online Only Promotion

Up to 50% OFF! Starting
from $49/clone

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu29689	NM_001312891.2 Latest version!	Homo sapiens zinc finger CCHC-type containing 12 (ZCCHC12), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu29689	NM_173798.4 Latest version!	Homo sapiens zinc finger CCHC-type containing 12 (ZCCHC12), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
View Old Accession Versions >>
OHu29689	NM_001312891.1	Homo sapiens zinc finger CCHC-type containing 12 (ZCCHC12), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu29689	NM_173798.3	Homo sapiens zinc finger CCHC-type containing 12 (ZCCHC12), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
Hide Old Accession Versions >>

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ZCCHC12 ( NM_001312891.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001299820.1 Homo sapiens zinc finger CCHC-type containing 12 (ZCCHC12), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu29689
Clone ID Related Accession (Same CDS sequence)	NM_001312891.1 , NM_001312891.2 , NM_173798.3 , NM_173798.4
Accession Version	NM_001312891.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1209bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-30
Organism	Homo sapiens(human)
Product	zinc finger CCHC domain-containing protein 12
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA075574.1, HY006302.1, AK122676.1 and AW002115.1. Transcript Variant: This variant (2) lacks an alternate exon in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein. ##Evidence-Data-START## Transcript exon combination :: SRR1660809.23168.1, SRR1803613.55282.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTAGCA TCATTGCACG TGTCGGTAAC AGCCGGCGGC TGAATGCACC CTTGCCGCCT 
TGGGCCCATT CCATGCTGAG GTCCCTGGGG AGAAGTCTCG GTCCTATAAT GGCCAGCATG 
GCAGACAGAA ACATGAAGTT GTTCTCGGGG AGGGTGGTGC CAGCCCAAGG GGAAGAAACC 
TTTGAAAACT GGCTGACCCA AGTCAATGGC GTCCTGCCAG ATTGGAATAT GTCTGAGGAG 
GAAAAGCTCA AGCGCTTGAT GAAAACCCTT AGGGGCCCTG CCCGCGAGGT CATGCGTGTG 
CTTCAGGCGA CCAACCCTAA CCTAAGTGTG GCAGATTTCT TGCGAGCCAT GAAATTGGTG 
TTTGGGGAGT CTGAAAGCAG TGTGACTGCC CATGGTAAAT TTTTTAACAC CCTACAAGCT 
CAAGGGGAGA AAGCCTCCCT TTATGTGATC CGTTTAGAGG TGCAGCTCCA GAACGCTATT 
CAGGCAGGCA TTATAGCTGA GAAAGATGCA AACCGGACTC GCTTGCAGCA GCTCCTTTTA 
GGCGGTGAGC TGAGTAGGGA CCTCCGACTC AGACTTAAGG ATTTTCTCAG GATGTATGCA 
AATGAGCAGG AGCGGCTTCC CAACTTTCTG GAGTTAATCA GAATGGTAAG GGAGGAAGAG 
GATTGGGATG ATGCTTTTAT TAAACGGAAG CGTCCAAAAA GGTCTGAGTC AATGGTGGAG 
AGGGCAGTCA GCCCTGTGGC ATTTCAGGGC TCCCCACCGA TAGTGATCGG CAGTGCTGAC 
TGCAATGTGA TAGAGATAGA TGATACCCTC GACGACTCCG ATGAGGATGT GATCCTGGTG 
GAGTCTCAGG ACCCTCCACT TCCATCCTGG GGTGCCCCTC CCCTCAGAGA CAGGGCCAGA 
CCTCAGGATG AAGTGCTGGT CATTGATTCC CCCCACAATT CCAGGGCTCA GTTTCCTTCC 
ACCAGTGGTG GTTCTGGCTA TAAGAATAAC GGTCCTGGGG AGATGCGTAG AGCCAGGAAG 
CGAAAACACA CAATCCGCTG TTCGTATTGT GGTGAGGAAG GCCACTCAAA AGAAACCTGT 
GACAACGAGA GTGACAAGGC CCAGGTTTTT GAGAATTTGA TCATCACTCT CCAGGAGCTG 
ACCCATACTG AGATGGAGAG GTCAAGAGTG GCCCCTGGCG AATACAATGA CTTCTCTGAG 
CCACTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001299820.1
CDS	503..1711
Translation	MASIIARVGNSRRLNAPLPPWAHSMLRSLGRSLGPIMASMADRNMKLFSGRVVPAQGEETFENWLTQVNGVLPDWNMSEEEKLKRLMKTLRGPAREVMRVLQATNPNLSVADFLRAMKLVFGESESSVTAHGKFFNTLQAQGEKASLYVIRLEVQLQNAIQAGIIAEKDANRTRLQQLLLGGELSRDLRLRLKDFLRMYANEQERLPNFLELIRMVREEEDWDDAFIKRKRPKRSESMVERAVSPVAFQGSPPIVIGSADCNVIEIDDTLDDSDEDVILVESQDPPLPSWGAPPLRDRARPQDEVLVIDSPHNSRAQFPSTSGGSGYKNNGPGEMRRARKRKHTIRCSYCGEEGHSKETCDNESDKAQVFENLIITLQELTHTEMERSRVAPGEYNDFSEPL

Target ORF information:

RefSeq Version	NM_001312891.1
Organism	Homo sapiens(human)
Definition	Homo sapiens zinc finger CCHC-type containing 12 (ZCCHC12), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001312891.1

ORF Insert Sequence:

ATGGCTAGCA TCATTGCACG TGTCGGTAAC AGCCGGCGGC TGAATGCACC CTTGCCGCCT 
TGGGCCCATT CCATGCTGAG GTCCCTGGGG AGAAGTCTCG GTCCTATAAT GGCCAGCATG 
GCAGACAGAA ACATGAAGTT GTTCTCGGGG AGGGTGGTGC CAGCCCAAGG GGAAGAAACC 
TTTGAAAACT GGCTGACCCA AGTCAATGGC GTCCTGCCAG ATTGGAATAT GTCTGAGGAG 
GAAAAGCTCA AGCGCTTGAT GAAAACCCTT AGGGGCCCTG CCCGCGAGGT CATGCGTGTG 
CTTCAGGCGA CCAACCCTAA CCTAAGTGTG GCAGATTTCT TGCGAGCCAT GAAATTGGTG 
TTTGGGGAGT CTGAAAGCAG TGTGACTGCC CATGGTAAAT TTTTTAACAC CCTACAAGCT 
CAAGGGGAGA AAGCCTCCCT TTATGTGATC CGTTTAGAGG TGCAGCTCCA GAACGCTATT 
CAGGCAGGCA TTATAGCTGA GAAAGATGCA AACCGGACTC GCTTGCAGCA GCTCCTTTTA 
GGCGGTGAGC TGAGTAGGGA CCTCCGACTC AGACTTAAGG ATTTTCTCAG GATGTATGCA 
AATGAGCAGG AGCGGCTTCC CAACTTTCTG GAGTTAATCA GAATGGTAAG GGAGGAAGAG 
GATTGGGATG ATGCTTTTAT TAAACGGAAG CGTCCAAAAA GGTCTGAGTC AATGGTGGAG 
AGGGCAGTCA GCCCTGTGGC ATTTCAGGGC TCCCCACCGA TAGTGATCGG CAGTGCTGAC 
TGCAATGTGA TAGAGATAGA TGATACCCTC GACGACTCCG ATGAGGATGT GATCCTGGTG 
GAGTCTCAGG ACCCTCCACT TCCATCCTGG GGTGCCCCTC CCCTCAGAGA CAGGGCCAGA 
CCTCAGGATG AAGTGCTGGT CATTGATTCC CCCCACAATT CCAGGGCTCA GTTTCCTTCC 
ACCAGTGGTG GTTCTGGCTA TAAGAATAAC GGTCCTGGGG AGATGCGTAG AGCCAGGAAG 
CGAAAACACA CAATCCGCTG TTCGTATTGT GGTGAGGAAG GCCACTCAAA AGAAACCTGT 
GACAACGAGA GTGACAAGGC CCAGGTTTTT GAGAATTTGA TCATCACTCT CCAGGAGCTG 
ACCCATACTG AGATGGAGAG GTCAAGAGTG GCCCCTGGCG AATACAATGA CTTCTCTGAG 
CCACTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ZCCHC12 ( NM_001312891.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001299820.1 Homo sapiens zinc finger CCHC-type containing 12 (ZCCHC12), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu29689
Clone ID Related Accession (Same CDS sequence)	NM_001312891.1 , NM_001312891.2 , NM_173798.3 , NM_173798.4
Accession Version	NM_001312891.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1209bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-09
Organism	Homo sapiens(human)
Product	zinc finger CCHC domain-containing protein 12
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA075574.1, HY006302.1, AK122676.1 and AW002115.1. On May 31, 2019 this sequence version replaced NM_001312891.1. Transcript Variant: This variant (2) lacks an alternate exon in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein. ##Evidence-Data-START## Transcript exon combination :: SRR1803616.157135.1, SRR1660807.116763.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTAGCA TCATTGCACG TGTCGGTAAC AGCCGGCGGC TGAATGCACC CTTGCCGCCT 
TGGGCCCATT CCATGCTGAG GTCCCTGGGG AGAAGTCTCG GTCCTATAAT GGCCAGCATG 
GCAGACAGAA ACATGAAGTT GTTCTCGGGG AGGGTGGTGC CAGCCCAAGG GGAAGAAACC 
TTTGAAAACT GGCTGACCCA AGTCAATGGC GTCCTGCCAG ATTGGAATAT GTCTGAGGAG 
GAAAAGCTCA AGCGCTTGAT GAAAACCCTT AGGGGCCCTG CCCGCGAGGT CATGCGTGTG 
CTTCAGGCGA CCAACCCTAA CCTAAGTGTG GCAGATTTCT TGCGAGCCAT GAAATTGGTG 
TTTGGGGAGT CTGAAAGCAG TGTGACTGCC CATGGTAAAT TTTTTAACAC CCTACAAGCT 
CAAGGGGAGA AAGCCTCCCT TTATGTGATC CGTTTAGAGG TGCAGCTCCA GAACGCTATT 
CAGGCAGGCA TTATAGCTGA GAAAGATGCA AACCGGACTC GCTTGCAGCA GCTCCTTTTA 
GGCGGTGAGC TGAGTAGGGA CCTCCGACTC AGACTTAAGG ATTTTCTCAG GATGTATGCA 
AATGAGCAGG AGCGGCTTCC CAACTTTCTG GAGTTAATCA GAATGGTAAG GGAGGAAGAG 
GATTGGGATG ATGCTTTTAT TAAACGGAAG CGTCCAAAAA GGTCTGAGTC AATGGTGGAG 
AGGGCAGTCA GCCCTGTGGC ATTTCAGGGC TCCCCACCGA TAGTGATCGG CAGTGCTGAC 
TGCAATGTGA TAGAGATAGA TGATACCCTC GACGACTCCG ATGAGGATGT GATCCTGGTG 
GAGTCTCAGG ACCCTCCACT TCCATCCTGG GGTGCCCCTC CCCTCAGAGA CAGGGCCAGA 
CCTCAGGATG AAGTGCTGGT CATTGATTCC CCCCACAATT CCAGGGCTCA GTTTCCTTCC 
ACCAGTGGTG GTTCTGGCTA TAAGAATAAC GGTCCTGGGG AGATGCGTAG AGCCAGGAAG 
CGAAAACACA CAATCCGCTG TTCGTATTGT GGTGAGGAAG GCCACTCAAA AGAAACCTGT 
GACAACGAGA GTGACAAGGC CCAGGTTTTT GAGAATTTGA TCATCACTCT CCAGGAGCTG 
ACCCATACTG AGATGGAGAG GTCAAGAGTG GCCCCTGGCG AATACAATGA CTTCTCTGAG 
CCACTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001299820.1
CDS	422..1630
Translation	MASIIARVGNSRRLNAPLPPWAHSMLRSLGRSLGPIMASMADRNMKLFSGRVVPAQGEETFENWLTQVNGVLPDWNMSEEEKLKRLMKTLRGPAREVMRVLQATNPNLSVADFLRAMKLVFGESESSVTAHGKFFNTLQAQGEKASLYVIRLEVQLQNAIQAGIIAEKDANRTRLQQLLLGGELSRDLRLRLKDFLRMYANEQERLPNFLELIRMVREEEDWDDAFIKRKRPKRSESMVERAVSPVAFQGSPPIVIGSADCNVIEIDDTLDDSDEDVILVESQDPPLPSWGAPPLRDRARPQDEVLVIDSPHNSRAQFPSTSGGSGYKNNGPGEMRRARKRKHTIRCSYCGEEGHSKETCDNESDKAQVFENLIITLQELTHTEMERSRVAPGEYNDFSEPL

Target ORF information:

RefSeq Version	NM_001312891.2
Organism	Homo sapiens(human)
Definition	Homo sapiens zinc finger CCHC-type containing 12 (ZCCHC12), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001312891.2

ORF Insert Sequence:

ATGGCTAGCA TCATTGCACG TGTCGGTAAC AGCCGGCGGC TGAATGCACC CTTGCCGCCT 
TGGGCCCATT CCATGCTGAG GTCCCTGGGG AGAAGTCTCG GTCCTATAAT GGCCAGCATG 
GCAGACAGAA ACATGAAGTT GTTCTCGGGG AGGGTGGTGC CAGCCCAAGG GGAAGAAACC 
TTTGAAAACT GGCTGACCCA AGTCAATGGC GTCCTGCCAG ATTGGAATAT GTCTGAGGAG 
GAAAAGCTCA AGCGCTTGAT GAAAACCCTT AGGGGCCCTG CCCGCGAGGT CATGCGTGTG 
CTTCAGGCGA CCAACCCTAA CCTAAGTGTG GCAGATTTCT TGCGAGCCAT GAAATTGGTG 
TTTGGGGAGT CTGAAAGCAG TGTGACTGCC CATGGTAAAT TTTTTAACAC CCTACAAGCT 
CAAGGGGAGA AAGCCTCCCT TTATGTGATC CGTTTAGAGG TGCAGCTCCA GAACGCTATT 
CAGGCAGGCA TTATAGCTGA GAAAGATGCA AACCGGACTC GCTTGCAGCA GCTCCTTTTA 
GGCGGTGAGC TGAGTAGGGA CCTCCGACTC AGACTTAAGG ATTTTCTCAG GATGTATGCA 
AATGAGCAGG AGCGGCTTCC CAACTTTCTG GAGTTAATCA GAATGGTAAG GGAGGAAGAG 
GATTGGGATG ATGCTTTTAT TAAACGGAAG CGTCCAAAAA GGTCTGAGTC AATGGTGGAG 
AGGGCAGTCA GCCCTGTGGC ATTTCAGGGC TCCCCACCGA TAGTGATCGG CAGTGCTGAC 
TGCAATGTGA TAGAGATAGA TGATACCCTC GACGACTCCG ATGAGGATGT GATCCTGGTG 
GAGTCTCAGG ACCCTCCACT TCCATCCTGG GGTGCCCCTC CCCTCAGAGA CAGGGCCAGA 
CCTCAGGATG AAGTGCTGGT CATTGATTCC CCCCACAATT CCAGGGCTCA GTTTCCTTCC 
ACCAGTGGTG GTTCTGGCTA TAAGAATAAC GGTCCTGGGG AGATGCGTAG AGCCAGGAAG 
CGAAAACACA CAATCCGCTG TTCGTATTGT GGTGAGGAAG GCCACTCAAA AGAAACCTGT 
GACAACGAGA GTGACAAGGC CCAGGTTTTT GAGAATTTGA TCATCACTCT CCAGGAGCTG 
ACCCATACTG AGATGGAGAG GTCAAGAGTG GCCCCTGGCG AATACAATGA CTTCTCTGAG 
CCACTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ZCCHC12 ( NM_173798.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_776159.1 Homo sapiens zinc finger CCHC-type containing 12 (ZCCHC12), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu29689
Clone ID Related Accession (Same CDS sequence)	NM_001312891.1 , NM_001312891.2 , NM_173798.3 , NM_173798.4
Accession Version	NM_173798.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1209bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-02
Organism	Homo sapiens(human)
Product	zinc finger CCHC domain-containing protein 12
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA075574.1, AK122676.1 and AW002115.1. This sequence is a reference standard in the RefSeqGene project. On Aug 21, 2015 this sequence version replaced NM_173798.2. Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTAGCA TCATTGCACG TGTCGGTAAC AGCCGGCGGC TGAATGCACC CTTGCCGCCT 
TGGGCCCATT CCATGCTGAG GTCCCTGGGG AGAAGTCTCG GTCCTATAAT GGCCAGCATG 
GCAGACAGAA ACATGAAGTT GTTCTCGGGG AGGGTGGTGC CAGCCCAAGG GGAAGAAACC 
TTTGAAAACT GGCTGACCCA AGTCAATGGC GTCCTGCCAG ATTGGAATAT GTCTGAGGAG 
GAAAAGCTCA AGCGCTTGAT GAAAACCCTT AGGGGCCCTG CCCGCGAGGT CATGCGTGTG 
CTTCAGGCGA CCAACCCTAA CCTAAGTGTG GCAGATTTCT TGCGAGCCAT GAAATTGGTG 
TTTGGGGAGT CTGAAAGCAG TGTGACTGCC CATGGTAAAT TTTTTAACAC CCTACAAGCT 
CAAGGGGAGA AAGCCTCCCT TTATGTGATC CGTTTAGAGG TGCAGCTCCA GAACGCTATT 
CAGGCAGGCA TTATAGCTGA GAAAGATGCA AACCGGACTC GCTTGCAGCA GCTCCTTTTA 
GGCGGTGAGC TGAGTAGGGA CCTCCGACTC AGACTTAAGG ATTTTCTCAG GATGTATGCA 
AATGAGCAGG AGCGGCTTCC CAACTTTCTG GAGTTAATCA GAATGGTAAG GGAGGAAGAG 
GATTGGGATG ATGCTTTTAT TAAACGGAAG CGTCCAAAAA GGTCTGAGTC AATGGTGGAG 
AGGGCAGTCA GCCCTGTGGC ATTTCAGGGC TCCCCACCGA TAGTGATCGG CAGTGCTGAC 
TGCAATGTGA TAGAGATAGA TGATACCCTC GACGACTCCG ATGAGGATGT GATCCTGGTG 
GAGTCTCAGG ACCCTCCACT TCCATCCTGG GGTGCCCCTC CCCTCAGAGA CAGGGCCAGA 
CCTCAGGATG AAGTGCTGGT CATTGATTCC CCCCACAATT CCAGGGCTCA GTTTCCTTCC 
ACCAGTGGTG GTTCTGGCTA TAAGAATAAC GGTCCTGGGG AGATGCGTAG AGCCAGGAAG 
CGAAAACACA CAATCCGCTG TTCGTATTGT GGTGAGGAAG GCCACTCAAA AGAAACCTGT 
GACAACGAGA GTGACAAGGC CCAGGTTTTT GAGAATTTGA TCATCACTCT CCAGGAGCTG 
ACCCATACTG AGATGGAGAG GTCAAGAGTG GCCCCTGGCG AATACAATGA CTTCTCTGAG 
CCACTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_776159.1
CDS	555..1763
Translation	MASIIARVGNSRRLNAPLPPWAHSMLRSLGRSLGPIMASMADRNMKLFSGRVVPAQGEETFENWLTQVNGVLPDWNMSEEEKLKRLMKTLRGPAREVMRVLQATNPNLSVADFLRAMKLVFGESESSVTAHGKFFNTLQAQGEKASLYVIRLEVQLQNAIQAGIIAEKDANRTRLQQLLLGGELSRDLRLRLKDFLRMYANEQERLPNFLELIRMVREEEDWDDAFIKRKRPKRSESMVERAVSPVAFQGSPPIVIGSADCNVIEIDDTLDDSDEDVILVESQDPPLPSWGAPPLRDRARPQDEVLVIDSPHNSRAQFPSTSGGSGYKNNGPGEMRRARKRKHTIRCSYCGEEGHSKETCDNESDKAQVFENLIITLQELTHTEMERSRVAPGEYNDFSEPL

Target ORF information:

RefSeq Version	NM_173798.3
Organism	Homo sapiens(human)
Definition	Homo sapiens zinc finger CCHC-type containing 12 (ZCCHC12), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_173798.3

ORF Insert Sequence:

ATGGCTAGCA TCATTGCACG TGTCGGTAAC AGCCGGCGGC TGAATGCACC CTTGCCGCCT 
TGGGCCCATT CCATGCTGAG GTCCCTGGGG AGAAGTCTCG GTCCTATAAT GGCCAGCATG 
GCAGACAGAA ACATGAAGTT GTTCTCGGGG AGGGTGGTGC CAGCCCAAGG GGAAGAAACC 
TTTGAAAACT GGCTGACCCA AGTCAATGGC GTCCTGCCAG ATTGGAATAT GTCTGAGGAG 
GAAAAGCTCA AGCGCTTGAT GAAAACCCTT AGGGGCCCTG CCCGCGAGGT CATGCGTGTG 
CTTCAGGCGA CCAACCCTAA CCTAAGTGTG GCAGATTTCT TGCGAGCCAT GAAATTGGTG 
TTTGGGGAGT CTGAAAGCAG TGTGACTGCC CATGGTAAAT TTTTTAACAC CCTACAAGCT 
CAAGGGGAGA AAGCCTCCCT TTATGTGATC CGTTTAGAGG TGCAGCTCCA GAACGCTATT 
CAGGCAGGCA TTATAGCTGA GAAAGATGCA AACCGGACTC GCTTGCAGCA GCTCCTTTTA 
GGCGGTGAGC TGAGTAGGGA CCTCCGACTC AGACTTAAGG ATTTTCTCAG GATGTATGCA 
AATGAGCAGG AGCGGCTTCC CAACTTTCTG GAGTTAATCA GAATGGTAAG GGAGGAAGAG 
GATTGGGATG ATGCTTTTAT TAAACGGAAG CGTCCAAAAA GGTCTGAGTC AATGGTGGAG 
AGGGCAGTCA GCCCTGTGGC ATTTCAGGGC TCCCCACCGA TAGTGATCGG CAGTGCTGAC 
TGCAATGTGA TAGAGATAGA TGATACCCTC GACGACTCCG ATGAGGATGT GATCCTGGTG 
GAGTCTCAGG ACCCTCCACT TCCATCCTGG GGTGCCCCTC CCCTCAGAGA CAGGGCCAGA 
CCTCAGGATG AAGTGCTGGT CATTGATTCC CCCCACAATT CCAGGGCTCA GTTTCCTTCC 
ACCAGTGGTG GTTCTGGCTA TAAGAATAAC GGTCCTGGGG AGATGCGTAG AGCCAGGAAG 
CGAAAACACA CAATCCGCTG TTCGTATTGT GGTGAGGAAG GCCACTCAAA AGAAACCTGT 
GACAACGAGA GTGACAAGGC CCAGGTTTTT GAGAATTTGA TCATCACTCT CCAGGAGCTG 
ACCCATACTG AGATGGAGAG GTCAAGAGTG GCCCCTGGCG AATACAATGA CTTCTCTGAG 
CCACTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ZCCHC12 ( NM_173798.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_776159.1 Homo sapiens zinc finger CCHC-type containing 12 (ZCCHC12), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu29689
Clone ID Related Accession (Same CDS sequence)	NM_001312891.1 , NM_001312891.2 , NM_173798.3 , NM_173798.4
Accession Version	NM_173798.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1209bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-09
Organism	Homo sapiens(human)
Product	zinc finger CCHC domain-containing protein 12
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK122676.1 and AW002115.1. This sequence is a reference standard in the RefSeqGene project. On Nov 23, 2018 this sequence version replaced NM_173798.3. Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein. ##Evidence-Data-START## Transcript exon combination :: BC031241.1, BC036572.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000310164.3/ ENSP00000308921.2 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCTAGCA TCATTGCACG TGTCGGTAAC AGCCGGCGGC TGAATGCACC CTTGCCGCCT 
TGGGCCCATT CCATGCTGAG GTCCCTGGGG AGAAGTCTCG GTCCTATAAT GGCCAGCATG 
GCAGACAGAA ACATGAAGTT GTTCTCGGGG AGGGTGGTGC CAGCCCAAGG GGAAGAAACC 
TTTGAAAACT GGCTGACCCA AGTCAATGGC GTCCTGCCAG ATTGGAATAT GTCTGAGGAG 
GAAAAGCTCA AGCGCTTGAT GAAAACCCTT AGGGGCCCTG CCCGCGAGGT CATGCGTGTG 
CTTCAGGCGA CCAACCCTAA CCTAAGTGTG GCAGATTTCT TGCGAGCCAT GAAATTGGTG 
TTTGGGGAGT CTGAAAGCAG TGTGACTGCC CATGGTAAAT TTTTTAACAC CCTACAAGCT 
CAAGGGGAGA AAGCCTCCCT TTATGTGATC CGTTTAGAGG TGCAGCTCCA GAACGCTATT 
CAGGCAGGCA TTATAGCTGA GAAAGATGCA AACCGGACTC GCTTGCAGCA GCTCCTTTTA 
GGCGGTGAGC TGAGTAGGGA CCTCCGACTC AGACTTAAGG ATTTTCTCAG GATGTATGCA 
AATGAGCAGG AGCGGCTTCC CAACTTTCTG GAGTTAATCA GAATGGTAAG GGAGGAAGAG 
GATTGGGATG ATGCTTTTAT TAAACGGAAG CGTCCAAAAA GGTCTGAGTC AATGGTGGAG 
AGGGCAGTCA GCCCTGTGGC ATTTCAGGGC TCCCCACCGA TAGTGATCGG CAGTGCTGAC 
TGCAATGTGA TAGAGATAGA TGATACCCTC GACGACTCCG ATGAGGATGT GATCCTGGTG 
GAGTCTCAGG ACCCTCCACT TCCATCCTGG GGTGCCCCTC CCCTCAGAGA CAGGGCCAGA 
CCTCAGGATG AAGTGCTGGT CATTGATTCC CCCCACAATT CCAGGGCTCA GTTTCCTTCC 
ACCAGTGGTG GTTCTGGCTA TAAGAATAAC GGTCCTGGGG AGATGCGTAG AGCCAGGAAG 
CGAAAACACA CAATCCGCTG TTCGTATTGT GGTGAGGAAG GCCACTCAAA AGAAACCTGT 
GACAACGAGA GTGACAAGGC CCAGGTTTTT GAGAATTTGA TCATCACTCT CCAGGAGCTG 
ACCCATACTG AGATGGAGAG GTCAAGAGTG GCCCCTGGCG AATACAATGA CTTCTCTGAG 
CCACTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_776159.1
CDS	474..1682
Translation	MASIIARVGNSRRLNAPLPPWAHSMLRSLGRSLGPIMASMADRNMKLFSGRVVPAQGEETFENWLTQVNGVLPDWNMSEEEKLKRLMKTLRGPAREVMRVLQATNPNLSVADFLRAMKLVFGESESSVTAHGKFFNTLQAQGEKASLYVIRLEVQLQNAIQAGIIAEKDANRTRLQQLLLGGELSRDLRLRLKDFLRMYANEQERLPNFLELIRMVREEEDWDDAFIKRKRPKRSESMVERAVSPVAFQGSPPIVIGSADCNVIEIDDTLDDSDEDVILVESQDPPLPSWGAPPLRDRARPQDEVLVIDSPHNSRAQFPSTSGGSGYKNNGPGEMRRARKRKHTIRCSYCGEEGHSKETCDNESDKAQVFENLIITLQELTHTEMERSRVAPGEYNDFSEPL

Target ORF information:

RefSeq Version	NM_173798.4
Organism	Homo sapiens(human)
Definition	Homo sapiens zinc finger CCHC-type containing 12 (ZCCHC12), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_173798.4

ORF Insert Sequence:

ATGGCTAGCA TCATTGCACG TGTCGGTAAC AGCCGGCGGC TGAATGCACC CTTGCCGCCT 
TGGGCCCATT CCATGCTGAG GTCCCTGGGG AGAAGTCTCG GTCCTATAAT GGCCAGCATG 
GCAGACAGAA ACATGAAGTT GTTCTCGGGG AGGGTGGTGC CAGCCCAAGG GGAAGAAACC 
TTTGAAAACT GGCTGACCCA AGTCAATGGC GTCCTGCCAG ATTGGAATAT GTCTGAGGAG 
GAAAAGCTCA AGCGCTTGAT GAAAACCCTT AGGGGCCCTG CCCGCGAGGT CATGCGTGTG 
CTTCAGGCGA CCAACCCTAA CCTAAGTGTG GCAGATTTCT TGCGAGCCAT GAAATTGGTG 
TTTGGGGAGT CTGAAAGCAG TGTGACTGCC CATGGTAAAT TTTTTAACAC CCTACAAGCT 
CAAGGGGAGA AAGCCTCCCT TTATGTGATC CGTTTAGAGG TGCAGCTCCA GAACGCTATT 
CAGGCAGGCA TTATAGCTGA GAAAGATGCA AACCGGACTC GCTTGCAGCA GCTCCTTTTA 
GGCGGTGAGC TGAGTAGGGA CCTCCGACTC AGACTTAAGG ATTTTCTCAG GATGTATGCA 
AATGAGCAGG AGCGGCTTCC CAACTTTCTG GAGTTAATCA GAATGGTAAG GGAGGAAGAG 
GATTGGGATG ATGCTTTTAT TAAACGGAAG CGTCCAAAAA GGTCTGAGTC AATGGTGGAG 
AGGGCAGTCA GCCCTGTGGC ATTTCAGGGC TCCCCACCGA TAGTGATCGG CAGTGCTGAC 
TGCAATGTGA TAGAGATAGA TGATACCCTC GACGACTCCG ATGAGGATGT GATCCTGGTG 
GAGTCTCAGG ACCCTCCACT TCCATCCTGG GGTGCCCCTC CCCTCAGAGA CAGGGCCAGA 
CCTCAGGATG AAGTGCTGGT CATTGATTCC CCCCACAATT CCAGGGCTCA GTTTCCTTCC 
ACCAGTGGTG GTTCTGGCTA TAAGAATAAC GGTCCTGGGG AGATGCGTAG AGCCAGGAAG 
CGAAAACACA CAATCCGCTG TTCGTATTGT GGTGAGGAAG GCCACTCAAA AGAAACCTGT 
GACAACGAGA GTGACAAGGC CCAGGTTTTT GAGAATTTGA TCATCACTCT CCAGGAGCTG 
ACCCATACTG AGATGGAGAG GTCAAGAGTG GCCCCTGGCG AATACAATGA CTTCTCTGAG 
CCACTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Architecture of the human interactome defines protein communities and disease networks.
Nature545(7655)505-509(2017 05)
Huttlin EL,Bruckner RJ,Paulo JA,Cannon JR,Ting L,Baltier K,Colby G,Gebreab F,Gygi MP,Parzen H,Szpyt J,Tam S,Zarraga G,Pontano-Vaites L,Swarup S,White AE,Schweppe DK,Rad R,Erickson BK,Obar RA,Guruharsha KG,Li K,Artavanis-Tsakonas S,Gygi SP,Harper JW

ZCCHC12, a novel oncogene in papillary thyroid cancer.
Journal of cancer research and clinical oncology(2017 Apr)
Wang O,Zheng Z,Wang Q,Jin Y,Jin W,Wang Y,Chen E,Zhang X

Widespread macromolecular interaction perturbations in human genetic disorders.
Cell161(3)647-660(2015 Apr)
Sahni N,Yi S,Taipale M,Fuxman Bass JI,Coulombe-Huntington J,Yang F,Peng J,Weile J,Karras GI,Wang Y,Kov?cs IA,Kamburov A,Krykbaeva I,Lam MH,Tucker G,Khurana V,Sharma A,Liu YY,Yachie N,Zhong Q,Shen Y,Palagi A,San-Miguel A,Fan C,Balcha D,Dricot A,Jordan DM,Walsh JM,Shah AA,Yang X,Stoyanova AK,Leighton A,Calderwood MA,Jacob Y,Cusick ME,Salehi-Ashtiani K,Whitesell LJ,Sunyaev S,Berger B,Barab?si AL,Charloteaux B,Hill DE,Hao T,Roth FP,Xia Y,Walhout AJM,Lindquist S,Vidal M

ZCCHC12, a potential molecular marker of papillary thyroid carcinoma: a preliminary study.
Medical oncology (Northwood, London, England)29(3)1409-17(2012 Sep)
Li QL,Chen FJ,Lai R,Guo ZM,Luo R,Yang AK

XLMR candidate mouse gene, Zcchc12 (Sizn1) is a novel marker of Cajal-Retzius cells.
Gene expression patterns : GEP11(3-4)216-20(2011 Mar-Apr)
Cho G,Lim Y,Golden JA

REQUEST A QUOTE

EMAIL

[email protected]

PHONE

1-877-436-7274

ONLINE FORM

Online Quote Submission

ONLINE FORM

Online Quote Submission

ZCCHC12 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

REQUEST A QUOTE

EMAIL

PHONE

ONLINE FORM

ONLINE FORM

SUPPORT

COMPANY

SUPPORT

COMPANY