Gene Symbol | Vezf1 |
Entrez Gene ID | 22344 |
Full Name | vascular endothelial zinc finger 1 |
Synonyms | AI848691,AW046909,db1 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Vezf1 cDNA ORF clone
gRNAs
Gene Symbol | Vezf1 |
Entrez Gene ID | 22344 |
Full Name | vascular endothelial zinc finger 1 |
Synonyms | AI848691,AW046909,db1 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_011248969.1 | XP_011247271.1 | vascular endothelial zinc finger 1 isoform X2 |
NM_016686.4 | NP_057895.2 | vascular endothelial zinc finger 1 |
XM_011248968.3 | XP_011247270.1 | vascular endothelial zinc finger 1 isoform X1 |
XM_011248969.2 | XP_011247271.1 | vascular endothelial zinc finger 1 isoform X2 |
XM_011248968.2 | XP_011247270.1 | vascular endothelial zinc finger 1 isoform X1 |
XM_030245928.1 | XP_030101788.1 | vascular endothelial zinc finger 1 isoform X4 |
XM_030245929.1 | XP_030101789.1 | vascular endothelial zinc finger 1 isoform X5 |
XM_030245927.1 | XP_030101787.1 | vascular endothelial zinc finger 1 isoform X3 |
Mus musculus (house mouse) | Vezf1 | NP_057895.2 |
Danio rerio (zebrafish) | vezf1a | XP_695400.2 |
VEZF1 | XP_001103313.2 | |
Xenopus tropicalis (tropical clawed frog) | vezf1 | NP_001006865.1 |
Pan troglodytes (chimpanzee) | VEZF1 | XP_523805.3 |
Canis lupus familiaris (dog) | VEZF1 | XP_003639340.1 |
Bos taurus (cattle) | VEZF1 | NP_001095697.1 |
Rattus norvegicus (Norway rat) | Vezf1 | XP_006247183.1 |
Danio rerio (zebrafish) | vezf1b | NP_001073432.1 |
Homo sapiens (human) | VEZF1 | NP_009077.2 |
Gallus gallus (chicken) | VEZF1 | NP_001032916.1 |
RhoB controls coordination of adult angiogenesis and lymphangiogenesis following injury by regulating VEZF1-mediated transcription.
Gerald D, Adini I, Shechter S, Perruzzi C, Varnau J, Hopkins B, Kazerounian S, Kurschat P, Blachon S, Khedkar S, Bagchi M, Sherris D, Prendergast GC, Klagsbrun M, Stuhlmann H, Rigby AC, Nagy JA, Benjamin LE
Nature communications42824(2013)
Vezf1 protein binding sites genome-wide are associated with pausing of elongating RNA polymerase II.
Gowher H, Brick K, Camerini-Otero RD, Felsenfeld G
Proceedings of the National Academy of Sciences of the United States of America109(7)2370-5(2012 Feb)
Deficiency of autotaxin/lysophospholipase D results in head cavity formation in mouse embryos through the LPA receptor-Rho-ROCK pathway.
Koike S, Keino-Masu K, Masu M
Biochemical and biophysical research communications400(1)66-71(2010 Sep)
Targeted Vezf1-null mutation impairs vascular structure formation during embryonic stem cell differentiation.
Zou Z, Ocaya PA, Sun H, Kuhnert F, Stuhlmann H
Arteriosclerosis, thrombosis, and vascular biology30(7)1378-88(2010 Jul)
Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.
Guo G, Huss M, Tong GQ, Wang C, Li Sun L, Clarke ND, Robson P
Developmental cell18(4)675-85(2010 Apr)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Nuclear RhoB-GTP controls expression of distinct gene sets in each endothelial lineage by regulating VEZF1-mediated transcription.
Title: RhoB controls coordination of adult angiogenesis and lymphangiogenesis following injury by regulating VEZF1-mediated transcription.
find examples of genes in which Vezf1 binding sites are located near cassette exons, and in which loss of Vezf1 leads to a change in the relative abundance of alternatively spliced messages
Title: Vezf1 protein binding sites genome-wide are associated with pausing of elongating RNA polymerase II.
Suggest that Vezf1 is involved in early differentiation processes of the vasculature by regulating cell differentiation, proliferation, and ECM distribution and deposition.
Title: Targeted Vezf1-null mutation impairs vascular structure formation during embryonic stem cell differentiation.
Vezf1 regulates genomic DNA methylation through its effects on expression of DNA methyltransferase Dnmt3b.
Title: Vezf1 regulates genomic DNA methylation through its effects on expression of DNA methyltransferase Dnmt3b.
In the developing embryo, Vezf1 is expressed in the yolk sac mesoderm and the endothelium of the developing vasculature and, in addition, in mesodermal and neuronal tissues.
Title: Dosage-dependent requirement for mouse Vezf1 in vascular system development.
The following Vezf1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Vezf1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu57806 | |
Clone ID Related Accession (Same CDS sequence) | XM_011248969.1 , XM_011248969.2 | |
Accession Version | XM_011248969.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1161bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | vascular endothelial zinc finger 1 isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000077.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_011248969.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGAGGCCA ACTGGACCGC GTTCCTGTTC CAGGCCCACG AAGCATCCCA TCACCAACAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011247271.1 |
CDS | 203..1363 |
Translation |
Target ORF information:
Target ORF information:
|
XM_011248969.2 |
1 | ATGGAGGCCA ACTGGACCGC GTTCCTGTTC CAGGCCCACG AAGCATCCCA TCACCAACAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu85770 | |
Clone ID Related Accession (Same CDS sequence) | XM_030245927.1 | |
Accession Version | XM_030245927.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1143bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | vascular endothelial zinc finger 1 isoform X3 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000077.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGAGGCCA ACTGGACCGC GTTCCTGTTC CAGGCCCACG AAGCATCCCA TCACCAACAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_030101787.1 |
CDS | 201..1343 |
Translation |
Target ORF information:
Target ORF information:
|
XM_030245927.1 |
1 | ATGGAGGCCA ACTGGACCGC GTTCCTGTTC CAGGCCCACG AAGCATCCCA TCACCAACAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu85771 | |
Clone ID Related Accession (Same CDS sequence) | XM_030245928.1 | |
Accession Version | XM_030245928.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1107bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | vascular endothelial zinc finger 1 isoform X4 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000077.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCCTGTGC CCCAGTCTGT CAAGAAACCC AGTAAGCCTG TCAAGAAGAA CCACGCCTGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_030101788.1 |
CDS | 3361..4467 |
Translation |
Target ORF information:
Target ORF information:
|
XM_030245928.1 |
1 | ATGCCTGTGC CCCAGTCTGT CAAGAAACCC AGTAAGCCTG TCAAGAAGAA CCACGCCTGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu85772 | |
Clone ID Related Accession (Same CDS sequence) | XM_030245929.1 | |
Accession Version | XM_030245929.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1089bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | vascular endothelial zinc finger 1 isoform X5 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000077.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCCTGTGC CCCAGTCTGT CAAGAAACCC AGTAAGCCTG TCAAGAAGAA CCACGCCTGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_030101789.1 |
CDS | 3361..4449 |
Translation |
Target ORF information:
Target ORF information:
|
XM_030245929.1 |
1 | ATGCCTGTGC CCCAGTCTGT CAAGAAACCC AGTAAGCCTG TCAAGAAGAA CCACGCCTGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu57805 | |
Clone ID Related Accession (Same CDS sequence) | XM_011248968.3 , XM_011248968.2 | |
Accession Version | XM_011248968.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1575bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | vascular endothelial zinc finger 1 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000077.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_011248968.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGAGGCCA ACTGGACCGC GTTCCTGTTC CAGGCCCACG AAGCATCCCA TCACCAACAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011247270.1 |
CDS | 198..1772 |
Translation |
Target ORF information:
Target ORF information:
|
XM_011248968.3 |
1 | ATGGAGGCCA ACTGGACCGC GTTCCTGTTC CAGGCCCACG AAGCATCCCA TCACCAACAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu25274 | |
Clone ID Related Accession (Same CDS sequence) | NM_016686.4 | |
Accession Version | NM_016686.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1557bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-05-25 | |
Organism | Mus musculus(house mouse) | |
Product | vascular endothelial zinc finger 1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL593853.11 and BX525225.1. On Sep 25, 2012 this sequence version replaced NM_016686.3. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF104410.3 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGAGGCCA ACTGGACCGC GTTCCTGTTC CAGGCCCACG AAGCATCCCA TCACCAACAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_057895.2 |
CDS | 123..1679 |
Translation |
Target ORF information:
Target ORF information:
|
NM_016686.4 |
1 | ATGGAGGCCA ACTGGACCGC GTTCCTGTTC CAGGCCCACG AAGCATCCCA TCACCAACAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu57805 | |
Clone ID Related Accession (Same CDS sequence) | XM_011248968.3 , XM_011248968.2 | |
Accession Version | XM_011248968.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1575bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | vascular endothelial zinc finger 1 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000077.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_011248968.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGAGGCCA ACTGGACCGC GTTCCTGTTC CAGGCCCACG AAGCATCCCA TCACCAACAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011247270.1 |
CDS | 142..1716 |
Translation |
Target ORF information:
Target ORF information:
|
XM_011248968.2 |
1 | ATGGAGGCCA ACTGGACCGC GTTCCTGTTC CAGGCCCACG AAGCATCCCA TCACCAACAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu57806 | |
Clone ID Related Accession (Same CDS sequence) | XM_011248969.1 , XM_011248969.2 | |
Accession Version | XM_011248969.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1161bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | vascular endothelial zinc finger 1 isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000077.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGAGGCCA ACTGGACCGC GTTCCTGTTC CAGGCCCACG AAGCATCCCA TCACCAACAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011247271.1 |
CDS | 146..1306 |
Translation |
Target ORF information:
Target ORF information:
|
XM_011248969.1 |
1 | ATGGAGGCCA ACTGGACCGC GTTCCTGTTC CAGGCCCACG AAGCATCCCA TCACCAACAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RhoB controls coordination of adult angiogenesis and lymphangiogenesis following injury by regulating VEZF1-mediated transcription. |
Vezf1 protein binding sites genome-wide are associated with pausing of elongating RNA polymerase II. |
Deficiency of autotaxin/lysophospholipase D results in head cavity formation in mouse embryos through the LPA receptor-Rho-ROCK pathway. |
Targeted Vezf1-null mutation impairs vascular structure formation during embryonic stem cell differentiation. |
Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst. |