Gene Symbol | TNRC6C |
Entrez Gene ID | 57690 |
Full Name | trinucleotide repeat containing 6C |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Disorder MIM: |
ORF » Species Summary » Homo sapiens » TNRC6C cDNA ORF clone
gRNAs
Gene Symbol | TNRC6C |
Entrez Gene ID | 57690 |
Full Name | trinucleotide repeat containing 6C |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Disorder MIM: |
mRNA | Protein | Name |
---|---|---|
XM_017024906.1 | XP_016880395.1 | trinucleotide repeat-containing gene 6C protein isoform X2 |
XM_024450848.1 | XP_024306616.1 | trinucleotide repeat-containing gene 6C protein isoform X3 |
XM_017024907.1 | XP_016880396.1 | trinucleotide repeat-containing gene 6C protein isoform X4 |
XM_011525088.2 | XP_011523390.1 | trinucleotide repeat-containing gene 6C protein isoform X6 |
NM_001142640.1 | NP_001136112.1 | trinucleotide repeat-containing gene 6C protein isoform 1 |
XM_006721996.3 | XP_006722059.3 | trinucleotide repeat-containing gene 6C protein isoform X1 |
XM_017024908.1 | XP_016880397.1 | trinucleotide repeat-containing gene 6C protein isoform X5 |
NM_018996.3 | NP_061869.2 | trinucleotide repeat-containing gene 6C protein isoform 2 |
XM_006721997.4 | XP_006722060.3 | trinucleotide repeat-containing gene 6C protein isoform X5 |
XM_006722000.3 | XP_006722063.3 | trinucleotide repeat-containing gene 6C protein isoform X7 |
XM_006721996.4 | XP_006722059.3 | trinucleotide repeat-containing gene 6C protein isoform X1 |
XM_006721997.3 | XP_006722060.3 | trinucleotide repeat-containing gene 6C protein isoform X4 |
XM_006722000.4 | XP_006722063.3 | trinucleotide repeat-containing gene 6C protein isoform X7 |
Pan troglodytes (chimpanzee) | TNRC6C | XP_001144739.2 |
Homo sapiens (human) | TNRC6C | NP_001136112.1 |
Canis lupus familiaris (dog) | TNRC6C | XP_005624105.1 |
Xenopus tropicalis (tropical clawed frog) | tnrc6c | XP_004918490.1 |
Danio rerio (zebrafish) | tnrc6c | XP_005164150.1 |
TNRC6C | XP_001104782.2 | |
Bos taurus (cattle) | TNRC6C | XP_005221355.1 |
Rattus norvegicus (Norway rat) | Tnrc6c | XP_006247910.1 |
Mus musculus (house mouse) | Tnrc6c | NP_932139.2 |
Gallus gallus (chicken) | TNRC6C | XP_004946156.1 |
Early origin and adaptive evolution of the GW182 protein family, the key component of RNA silencing in animals.
Zielezinski A, Karlowski WM
RNA biology12(7)761-70(2015)
A DDX6-CNOT1 complex and W-binding pockets in CNOT9 reveal direct links between miRNA target recognition and silencing.
Chen Y, Boland A, Kuzuo?lu-?zt?rk D, Bawankar P, Loh B, Chang CT, Weichenrieder O, Izaurralde E
Molecular cell54(5)737-50(2014 Jun)
Genome-wide association analyses suggest NELL1 influences adverse metabolic response to HCTZ in African Americans.
Del-Aguila JL, Beitelshees AL, Cooper-Dehoff RM, Chapman AB, Gums JG, Bailey K, Gong Y, Turner ST, Johnson JA, Boerwinkle E
The pharmacogenomics journal14(1)35-40(2014 Feb)
GW182 proteins cause PABP dissociation from silenced miRNA targets in the absence of deadenylation.
Zekri L, Kuzuo?lu-?zt?rk D, Izaurralde E
The EMBO journal32(7)1052-65(2013 Apr)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
These findings reveal that despite species-specific differences in the relative strength of the PABPC1-binding sites, the interaction between GW182 proteins and PABPC1 is critical for miRNA-mediated silencing in animal cells.
Title: Two PABPC1-binding sites in GW182 proteins promote miRNA-mediated gene silencing.
The authors show that a conserved motif in the human GW182 paralog TNRC6C interacts with the C-terminal domain of polyadenylate binding protein 1 (PABC) and present the crystal structure of the complex.
Title: Structural insights into the human GW182-PABC interaction in microRNA-mediated deadenylation.
Our findings indicate that TNRC6C, is recruited to miRNA targets through an interaction between their N-terminal domain and an Argonaute protein
Title: The C-terminal domains of human TNRC6A, TNRC6B, and TNRC6C silence bound transcripts independently of Argonaute proteins.
Through deletion and mutagenesis, study identified the C-terminal part of TNRC6C encompassing the RRM RNA-binding motif as a key effector domain mediating protein synthesis repression by TNRC6C.
Title: Importance of the C-terminal domain of the human GW182 protein TNRC6C for translational repression.
The following TNRC6C gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TNRC6C cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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CloneID | OHu70848 | |
Clone ID Related Accession (Same CDS sequence) | XM_024450848.1 | |
Accession Version | XM_024450848.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 5820bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-05 | |
Organism | Homo sapiens(human) | |
Product | trinucleotide repeat-containing gene 6C protein isoform X3 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000017.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGAAGAAA AGAAAAAGAA AAAGCAGGAA GAAAAGAAAA AGAAGGAAGG TGCTCAGAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_024306616.1 |
CDS | 454..6273 |
Translation |
Target ORF information:
Target ORF information:
|
XM_024450848.1 |
1 | ATGGAAGAAA AGAAAAAGAA AAAGCAGGAA GAAAAGAAAA AGAAGGAAGG TGCTCAGAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu87010 | |
Clone ID Related Accession (Same CDS sequence) | XM_006721996.3 , XM_006721996.4 | |
Accession Version | XM_006721996.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 5916bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-05 | |
Organism | Homo sapiens(human) | |
Product | trinucleotide repeat-containing gene 6C protein isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000017.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_006721996.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTGTGAGG GTTTCTTCTC ACACATCAAA CAAGCAAGGA GTTCTGCTGT GGATATCAGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006722059.3 |
CDS | 5527..11442 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006721996.3 |
1 | ATGTGTGAGG GTTTCTTCTC ACACATCAAA CAAGCAAGGA GTTCTGCTGT GGATATCAGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu87010 | |
Clone ID Related Accession (Same CDS sequence) | XM_006721996.3 , XM_006721996.4 | |
Accession Version | XM_006721996.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 5916bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-05 | |
Organism | Homo sapiens(human) | |
Product | trinucleotide repeat-containing gene 6C protein isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000017.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_006721996.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTGTGAGG GTTTCTTCTC ACACATCAAA CAAGCAAGGA GTTCTGCTGT GGATATCAGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006722059.3 |
CDS | 5527..11442 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006721996.4 |
1 | ATGTGTGAGG GTTTCTTCTC ACACATCAAA CAAGCAAGGA GTTCTGCTGT GGATATCAGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu87011 | |
Clone ID Related Accession (Same CDS sequence) | XM_017024906.1 | |
Accession Version | XM_017024906.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 5907bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-05 | |
Organism | Homo sapiens(human) | |
Product | trinucleotide repeat-containing gene 6C protein isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000017.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTGTGAGG GTTTCTTCTC ACACATCAAA CAAGCAAGGA GTTCTGCTGT GGATATCAGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_016880395.1 |
CDS | 5527..11433 |
Translation |
Target ORF information:
Target ORF information:
|
XM_017024906.1 |
1 | ATGTGTGAGG GTTTCTTCTC ACACATCAAA CAAGCAAGGA GTTCTGCTGT GGATATCAGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu87012 | |
Clone ID Related Accession (Same CDS sequence) | XM_017024907.1 | |
Accession Version | XM_017024907.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 5799bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-05 | |
Organism | Homo sapiens(human) | |
Product | trinucleotide repeat-containing gene 6C protein isoform X4 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000017.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTGTGAGG GTTTCTTCTC ACACATCAAA CAAGCAAGGA GTTCTGCTGT GGATATCAGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_016880396.1 |
CDS | 5527..11325 |
Translation |
Target ORF information:
Target ORF information:
|
XM_017024907.1 |
1 | ATGTGTGAGG GTTTCTTCTC ACACATCAAA CAAGCAAGGA GTTCTGCTGT GGATATCAGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu87013 | |
Clone ID Related Accession (Same CDS sequence) | XM_006721997.4 , XM_006721997.3 | |
Accession Version | XM_006721997.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 5766bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-05 | |
Organism | Homo sapiens(human) | |
Product | trinucleotide repeat-containing gene 6C protein isoform X5 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000017.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_006721997.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTGTGAGG GTTTCTTCTC ACACATCAAA CAAGCAAGGA GTTCTGCTGT GGATATCAGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006722060.3 |
CDS | 5527..11292 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006721997.4 |
1 | ATGTGTGAGG GTTTCTTCTC ACACATCAAA CAAGCAAGGA GTTCTGCTGT GGATATCAGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu87013 | |
Clone ID Related Accession (Same CDS sequence) | XM_006721997.4 , XM_006721997.3 | |
Accession Version | XM_006721997.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 5766bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-05 | |
Organism | Homo sapiens(human) | |
Product | trinucleotide repeat-containing gene 6C protein isoform X4 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000017.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_006721997.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTGTGAGG GTTTCTTCTC ACACATCAAA CAAGCAAGGA GTTCTGCTGT GGATATCAGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006722060.3 |
CDS | 5527..11292 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006721997.3 |
1 | ATGTGTGAGG GTTTCTTCTC ACACATCAAA CAAGCAAGGA GTTCTGCTGT GGATATCAGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu87014 | |
Clone ID Related Accession (Same CDS sequence) | XM_017024908.1 | |
Accession Version | XM_017024908.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 5691bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-05 | |
Organism | Homo sapiens(human) | |
Product | trinucleotide repeat-containing gene 6C protein isoform X5 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000017.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTGTGAGG GTTTCTTCTC ACACATCAAA CAAGCAAGGA GTTCTGCTGT GGATATCAGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_016880397.1 |
CDS | 5527..11217 |
Translation |
Target ORF information:
Target ORF information:
|
XM_017024908.1 |
1 | ATGTGTGAGG GTTTCTTCTC ACACATCAAA CAAGCAAGGA GTTCTGCTGT GGATATCAGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu87015 | |
Clone ID Related Accession (Same CDS sequence) | XM_006722000.3 , XM_006722000.4 | |
Accession Version | XM_006722000.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 5790bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-05 | |
Organism | Homo sapiens(human) | |
Product | trinucleotide repeat-containing gene 6C protein isoform X7 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000017.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_006722000.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTGTGAGG GTTTCTTCTC ACACATCAAA CAAGCAAGGA GTTCTGCTGT GGATATCAGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006722063.3 |
CDS | 5527..11316 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006722000.3 |
1 | ATGTGTGAGG GTTTCTTCTC ACACATCAAA CAAGCAAGGA GTTCTGCTGT GGATATCAGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu87015 | |
Clone ID Related Accession (Same CDS sequence) | XM_006722000.3 , XM_006722000.4 | |
Accession Version | XM_006722000.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 5790bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-05 | |
Organism | Homo sapiens(human) | |
Product | trinucleotide repeat-containing gene 6C protein isoform X7 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000017.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_006722000.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTGTGAGG GTTTCTTCTC ACACATCAAA CAAGCAAGGA GTTCTGCTGT GGATATCAGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006722063.3 |
CDS | 5527..11316 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006722000.4 |
1 | ATGTGTGAGG GTTTCTTCTC ACACATCAAA CAAGCAAGGA GTTCTGCTGT GGATATCAGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu13632 | |
Clone ID Related Accession (Same CDS sequence) | NM_001142640.1 | |
Accession Version | NM_001142640.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 5181bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-06-25 | |
Organism | Homo sapiens(human) | |
Product | trinucleotide repeat-containing gene 6C protein isoform 1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DV080590.1, DA339992.1, AB046802.2, BC045631.1, AC021593.15 and AI337097.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGCTACAG GGAGTGCCCA GGGCAACTTC ACTGGACATA CCAAGAAGAC AAATGGCAAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001136112.1 |
CDS | 601..5781 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001142640.1 |
1 | ATGGCTACAG GGAGTGCCCA GGGCAACTTC ACTGGACATA CCAAGAAGAC AAATGGCAAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu13722 | |
Clone ID Related Accession (Same CDS sequence) | NM_018996.3 | |
Accession Version | NM_018996.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 5073bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-06-25 | |
Organism | Homo sapiens(human) | |
Product | trinucleotide repeat-containing gene 6C protein isoform 2 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DV080590.1, DA339992.1, AB046802.2, AC021593.15 and AI337097.1. On Dec 13, 2008 this sequence version replaced NM_018996.2. Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 5' coding region and lacks an alternate in-frame exon in the 3' coding region, compared to variant 1. The resulting isoform (2) has the same N- and C-termini but lacks a 3 amino acid segment near the N-terminus and a 39 amino acid segment near the C-terminus, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## CDS exon combination :: AB046802.2 [ECO:0000331] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA1970526 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGCTACAG GGAGTGCCCA GGGCAACTTC ACTGGACATA CCAAGAAGAC AAATGGCAAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_061869.2 |
CDS | 601..5673 |
Translation |
Target ORF information:
Target ORF information:
|
NM_018996.3 |
1 | ATGGCTACAG GGAGTGCCCA GGGCAACTTC ACTGGACATA CCAAGAAGAC AAATGGCAAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu70853 | |
Clone ID Related Accession (Same CDS sequence) | XM_011525088.2 | |
Accession Version | XM_011525088.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 5190bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-05 | |
Organism | Homo sapiens(human) | |
Product | trinucleotide repeat-containing gene 6C protein isoform X6 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000017.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011525088.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCTACAG GGAGTGCCCA GGGCAACTTC ACTGGACATA CCAAGAAGAC AAATGGCAAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011523390.1 |
CDS | 290..5479 |
Translation |
Target ORF information:
Target ORF information:
|
XM_011525088.2 |
1 | ATGGCTACAG GGAGTGCCCA GGGCAACTTC ACTGGACATA CCAAGAAGAC AAATGGCAAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Early origin and adaptive evolution of the GW182 protein family, the key component of RNA silencing in animals. |
A DDX6-CNOT1 complex and W-binding pockets in CNOT9 reveal direct links between miRNA target recognition and silencing. |
Genome-wide association analyses suggest NELL1 influences adverse metabolic response to HCTZ in African Americans. |
GW182 proteins cause PABP dissociation from silenced miRNA targets in the absence of deadenylation. |