Gene Symbol | Pi16 |
Entrez Gene ID | 74116 |
Full Name | peptidase inhibitor 16 |
Synonyms | 1200009H11Rik,Cripi,PI-16 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Pi16 cDNA ORF clone
gRNAs
Gene Symbol | Pi16 |
Entrez Gene ID | 74116 |
Full Name | peptidase inhibitor 16 |
Synonyms | 1200009H11Rik,Cripi,PI-16 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_006525015.3 | XP_006525078.1 | peptidase inhibitor 16 isoform X2 |
XM_006525014.1 | XP_006525077.1 | peptidase inhibitor 16 isoform X1 |
NM_023734.3 | NP_076223.3 | peptidase inhibitor 16 precursor |
XM_006525015.4 | XP_006525078.1 | peptidase inhibitor 16 isoform X2 |
Peptidase inhibitor 16 is a membrane-tethered regulator of chemerin processing in the myocardium.
Regn M, Laggerbauer B, Jentzsch C, Ramanujam D, Ahles A, Sichler S, Calzada-Wack J, Koenen RR, Braun A, Nieswandt B, Engelhardt S
Journal of molecular and cellular cardiology9957-64(2016 Oct)
A secretion trap screen in yeast identifies protease inhibitor 16 as a novel antihypertrophic protein secreted from the heart.
Frost RJ, Engelhardt S
Circulation116(16)1768-75(2007 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
our data indicate that PI16 suppresses chemerin activation in the myocardium and suggest that this circuit may be part of the cardiac stress response.
Title: Peptidase inhibitor 16 is a membrane-tethered regulator of chemerin processing in the myocardium.
PI16, a novel protein secreted from the heart, is strongly upregulated early in heart failure and inhibits growth of cardiomyocytes both in vitro and in vivo
Title: A secretion trap screen in yeast identifies protease inhibitor 16 as a novel antihypertrophic protein secreted from the heart.
The following Pi16 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Pi16 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu54097 | |
Clone ID Related Accession (Same CDS sequence) | XM_006525014.1 | |
Accession Version | XM_006525014.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 711bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | peptidase inhibitor 16 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000083.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCACGGTT CCTGCAGCCC GTGGGTGATG TTGCCGCCGC CACTGCTCCT CCTGCTGCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006525077.1 |
CDS | 420..1130 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006525014.1 |
1 | ATGCACGGTT CCTGCAGCCC GTGGGTGATG TTGCCGCCGC CACTGCTCCT CCTGCTGCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu54098 | |
Clone ID Related Accession (Same CDS sequence) | XM_006525015.3 , XM_006525015.4 | |
Accession Version | XM_006525015.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 618bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | peptidase inhibitor 16 isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000083.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006525015.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCACGGTT CCTGCAGCCC GTGGGTGATG TTGCCGCCGC CACTGCTCCT CCTGCTGCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006525078.1 |
CDS | 420..1037 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006525015.3 |
1 | ATGCACGGTT CCTGCAGCCC GTGGGTGATG TTGCCGCCGC CACTGCTCCT CCTGCTGCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu54098 | |
Clone ID Related Accession (Same CDS sequence) | XM_006525015.3 , XM_006525015.4 | |
Accession Version | XM_006525015.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 618bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | peptidase inhibitor 16 isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000083.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006525015.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCACGGTT CCTGCAGCCC GTGGGTGATG TTGCCGCCGC CACTGCTCCT CCTGCTGCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006525078.1 |
CDS | 420..1037 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006525015.4 |
1 | ATGCACGGTT CCTGCAGCCC GTGGGTGATG TTGCCGCCGC CACTGCTCCT CCTGCTGCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu20711 | |
Clone ID Related Accession (Same CDS sequence) | NM_023734.3 | |
Accession Version | NM_023734.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1497bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-02-16 | |
Organism | Mus musculus(house mouse) | |
Product | peptidase inhibitor 16 precursor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK157854.1, AI587910.1 and AB046537.1. On Oct 13, 2006 this sequence version replaced NM_023734.2. ##Evidence-Data-START## Transcript exon combination :: AB046537.1, BC039124.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGCACGGTT CCTGCAGCCC GTGGGTGATG TTGCCGCCGC CACTGCTCCT CCTGCTGCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_076223.3 |
CDS | 334..1830 |
Translation |
Target ORF information:
Target ORF information:
|
NM_023734.3 |
1 | ATGCACGGTT CCTGCAGCCC GTGGGTGATG TTGCCGCCGC CACTGCTCCT CCTGCTGCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Peptidase inhibitor 16 is a membrane-tethered regulator of chemerin processing in the myocardium. |
A secretion trap screen in yeast identifies protease inhibitor 16 as a novel antihypertrophic protein secreted from the heart. |