RIOX1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Gene Symbol	RIOX1
Entrez Gene ID	79697
Full Name	ribosomal oxygenase 1
Synonyms	C14orf169,JMJD9,MAPJD,NO66,ROX,URLC2,hsNO66
General protein information	Preferred Names ribosomal oxygenase 1 Names ribosomal oxygenase 1 60S ribosomal protein L8 histidine hydroxylase MYC-associated protein with JmjC domain bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66 histone lysine demethylase NO66 lysine-specific demethylase NO66 nucleolar protein 66 ribosomal oxygenase NO66 up-regulated in lung cancer 2
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 14 Map Location: 14q24.3
Disorder MIM:	611919

mRNA and Protein(s)

mRNA Protein Name

NM_024644.4 NP_078920.2 ribosomal oxygenase 1

NM_024644.5 NP_078920.2 ribosomal oxygenase 1
Pathways from BioSystems

mRNA	Protein	Name
NM_024644.4	NP_078920.2	ribosomal oxygenase 1
NM_024644.5	NP_078920.2	ribosomal oxygenase 1

Homologies

	C7H14orf169	XP_001090820.1
Canis lupus familiaris (dog)	C8H14orf169	XP_005623685.1
Mus musculus (house mouse)	2410016O06Rik	NP_076122.2
Danio rerio (zebrafish)	zgc:162967	NP_001082857.1
Rattus norvegicus (Norway rat)	RGD1307704	NP_001101510.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP001938	XP_321123.4
Bos taurus (cattle)	NO66	NP_001093172.1
Xenopus tropicalis (tropical clawed frog)	LOC100488246	XP_002933911.1
Gallus gallus (chicken)	C5H14ORF169	NP_001026367.1
Homo sapiens (human)	C14orf169	NP_078920.2
Drosophila melanogaster (fruit fly)	CG2982	NP_572160.1

Gene Ontology
Bibliography

Related articles in PubMed

Clinical Significance of Histone Demethylase NO66 in Invasive Colorectal Cancer.
Nishizawa Y, Nishida N, Konno M, Kawamoto K, Asai A, Koseki J, Takahashi H, Haraguchi N, Nishimura J, Hata T, Matsuda C, Mizushima T, Satoh T, Doki Y, Mori M, Ishii H
Annals of surgical oncology24(3)841-849(2017 Mar)

Structure-function relationships of human JmjC oxygenases-demethylases versus hydroxylases.
Markolovic S, Leissing TM, Chowdhury R, Wilkins SE, Lu X, Schofield CJ
Current opinion in structural biology4162-72(2016 Dec)

Expression of histone methyltransferases as novel biomarkers for renal cell tumor diagnosis and prognostication.
Pires-Lu?s AS, Vieira-Coimbra M, Vieira FQ, Costa-Pinheiro P, Silva-Santos R, Dias PC, Antunes L, Lobo F, Oliveira J, Gon?alves CS, Costa BM, Henrique R, Jer?nimo C
Epigenetics10(11)1033-43(2015)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

confirmed the hydroxylase activity of NO66 and showed that oligomerization is required for NO66 to efficiently catalyze the hydroxylation of Rpl8
Title: Structure of the JmjC domain-containing protein NO66 complexed with ribosomal protein Rpl8.

Results show that high expression levels of SMYD2, SETD3, and NO66 in renal cell tumors. Their low expression levels were significantly associated with shorter disease-specific and disease-free survival.
Title: Expression of histone methyltransferases as novel biomarkers for renal cell tumor diagnosis and prognostication.

hinge domain-dependent oligomerization of NO66 is essential for inhibition of Osx-dependent gene activation.
Title: Structural insights into histone demethylase NO66 in interaction with osteoblast-specific transcription factor osterix and gene repression.

NO66 crystallized in space group P3(1) or P3(2), with unit-cell parameters a = 89.35, b = 89.35, c = 304.86 A, alpha = beta = 90, gamma = 120 degrees , and the crystal is likely to contain four molecules in the asymmetric unit
Title: Purification, crystallization and preliminary crystallographic analysis of histone lysine demethylase NO66 from Homo sapiens.

interactions between NO66 and Osx regulate Osx-target genes in osteoblasts by modulating histone methylation states
Title: Regulation of the osteoblast-specific transcription factor Osterix by NO66, a Jumonji family histone demethylase.

The following RIOX1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the RIOX1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu01455	NM_024644.5 Latest version!	Homo sapiens ribosomal oxygenase 1 (RIOX1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$265.30 $379.00
View Old Accession Versions >>
OHu01455	NM_024644.4	Homo sapiens ribosomal oxygenase 1 (RIOX1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$265.30 $379.00
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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

RIOX1 ( NM_024644.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_078920.2 Homo sapiens ribosomal oxygenase 1 (RIOX1), mRNA.

Price & Availability↑

CloneID	OHu01455
Clone ID Related Accession (Same CDS sequence)	NM_024644.4 , NM_024644.5
Accession Version	NM_024644.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1926bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-23
Organism	Homo sapiens(human)
Product	ribosomal oxygenase 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from HY178771.1, DA872764.1, DA509240.1, BC071954.1, CN259773.1 and BX390965.1. On Feb 19, 2014 this sequence version replaced NM_024644.3. ##Evidence-Data-START## Transcript is intronless :: AB101204.1 [ECO:0000345] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGATGGGC TCCAGGCCAG TGCAGGGCCG TTGAGGCGCG GGCGGCCGAA GCGCCGGCGC 
AAGCCCCAGC CACACAGCGG GTCGGTCCTG GCCCTGCCCT TGAGGTCCAG GAAGATACGA 
AAGCAGCTGC GAAGTGTTGT ATCCCGCATG GCAGCGCTGA GGACGCAGAC GCTGCCTAGC 
GAGAACTCGG AGGAATCGAG GGTGGAGTCG ACGGCCGACG ACCTGGGGGA CGCGCTACCC 
GGTGGGGCGG CGGTGGCGGC CGTCCCGGAC GCAGCCCGGC GAGAGCCATA CGGCCACCTG 
GGGCCCGCAG AGCTGCTGGA GGCCTCGCCC GCCGCGCGCT CCCTGCAGAC CCCGTCGGCG 
CGCCTGGTGC CCGCTTCCGC GCCGCCCGCG CGCCTGGTGG AGGTGCCCGC CGCGCCGGTC 
CGGGTGGTGG AGACCTCGGC CCTGCTGTGC ACCGCGCAAC ACTTAGCGGC CGTCCAGTCG 
TCCGGGGCCC CTGCGACGGC GTCGGGGCCG CAGGTGGATA ACACGGGTGG GGAGCCGGCC 
TGGGACTCCC CGCTGCGGCG CGTCTTGGCC GAGCTGAACC GCATCCCCAG CAGCCGGCGG 
CGAGCGGCCC GCCTCTTTGA GTGGCTCATC GCGCCCATGC CGCCAGATCA CTTTTACCGG 
CGCCTATGGG AGCGCGAGGC GGTGCTGGTG CGGCGGCAGG ACCACACCTA CTACCAGGGA 
CTTTTCTCTA CCGCTGACCT GGATTCGATG CTGCGCAACG AGGAGGTGCA GTTCGGCCAG 
CATTTGGACG CCGCTCGCTA CATCAACGGA CGACGCGAGA CCCTGAACCC ACCCGGCCGC 
GCGCTGCCCG CCGCCGCGTG GTCCCTGTAC CAGGCCGGCT GCTCCCTGCG TCTCCTCTGT 
CCGCAGGCTT TCTCTACTAC TGTGTGGCAG TTTTTGGCTG TGCTTCAAGA GCAGTTTGGA 
AGCATGGCAG GCTCCAACGT TTACCTCACG CCCCCTAACT CGCAGGGCTT TGCCCCCCAC 
TACGACGACA TCGAGGCCTT CGTGCTGCAG CTGGAAGGTA GGAAACTCTG GCGTGTATAC 
CGACCCCGAG TCCCAACCGA GGAACTGGCT CTGACATCCA GCCCCAACTT CAGTCAGGAC 
GACCTCGGTG AGCCGGTGCT GCAGACCGTG CTGGAACCTG GAGATTTGCT GTATTTTCCT 
CGGGGCTTCA TTCACCAAGC TGAATGCCAG GATGGAGTCC ACTCTCTGCA CCTCACCTTG 
TCCACGTACC AGCGCAATAC CTGGGGTGAC TTCTTAGAGG CCATACTGCC TCTGGCAGTG 
CAGGCTGCAA TGGAAGAAAA TGTGGAGTTT CGGAGGGGTC TGCCCCGAGA CTTCATGGAT 
TACATGGGGG CCCAGCATTC AGATTCTAAG GATCCGCGAA GAACCGCTTT CATGGAGAAG 
GTGCGGGTCT TGGTTGCCCG CCTGGGACAC TTTGCTCCTG TTGATGCTGT GGCCGACCAG 
CGAGCCAAAG ACTTCATTCA CGATTCTCTG CCCCCTGTTT TGACTGATAG GGAGAGGGCA 
CTAAGTGTTT ACGGGCTTCC AATTCGCTGG GAGGCTGGAG AACCTGTAAA CGTGGGGGCC 
CAGTTGACAA CAGAAACAGA AGTCCATATG CTTCAGGATG GGATAGCTCG GCTGGTGGGT 
GAGGGGGGCC ATTTGTTTCT CTATTACACA GTGGAAAACT CCCGTGTGTA TCATCTGGAA 
GAACCCAAGT GCTTGGAAAT ATACCCCCAG CAAGCTGATG CCATGGAACT GTTGCTTGGT 
TCTTATCCAG AGTTTGTGAG AGTGGGGGAC CTGCCCTGTG ACAGTGTGGA GGACCAGCTG 
TCCTTGGCAA CCACGTTGTA TGATAAGGGG CTGCTGCTCA CTAAGATGCC TCTAGCCCTA 
AATTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_078920.2
CDS	85..2010
Translation	MDGLQASAGPLRRGRPKRRRKPQPHSGSVLALPLRSRKIRKQLRSVVSRMAALRTQTLPSENSEESRVESTADDLGDALPGGAAVAAVPDAARREPYGHLGPAELLEASPAARSLQTPSARLVPASAPPARLVEVPAAPVRVVETSALLCTAQHLAAVQSSGAPATASGPQVDNTGGEPAWDSPLRRVLAELNRIPSSRRRAARLFEWLIAPMPPDHFYRRLWEREAVLVRRQDHTYYQGLFSTADLDSMLRNEEVQFGQHLDAARYINGRRETLNPPGRALPAAAWSLYQAGCSLRLLCPQAFSTTVWQFLAVLQEQFGSMAGSNVYLTPPNSQGFAPHYDDIEAFVLQLEGRKLWRVYRPRVPTEELALTSSPNFSQDDLGEPVLQTVLEPGDLLYFPRGFIHQAECQDGVHSLHLTLSTYQRNTWGDFLEAILPLAVQAAMEENVEFRRGLPRDFMDYMGAQHSDSKDPRRTAFMEKVRVLVARLGHFAPVDAVADQRAKDFIHDSLPPVLTDRERALSVYGLPIRWEAGEPVNVGAQLTTETEVHMLQDGIARLVGEGGHLFLYYTVENSRVYHLEEPKCLEIYPQQADAMELLLGSYPEFVRVGDLPCDSVEDQLSLATTLYDKGLLLTKMPLALN

Target ORF information:

RefSeq Version	NM_024644.4
Organism	Homo sapiens(human)
Definition	Homo sapiens ribosomal oxygenase 1 (RIOX1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_024644.4

ORF Insert Sequence:

ATGGATGGGC TCCAGGCCAG TGCAGGGCCG TTGAGGCGCG GGCGGCCGAA GCGCCGGCGC 
AAGCCCCAGC CACACAGCGG GTCGGTCCTG GCCCTGCCCT TGAGGTCCAG GAAGATACGA 
AAGCAGCTGC GAAGTGTTGT ATCCCGCATG GCAGCGCTGA GGACGCAGAC GCTGCCTAGC 
GAGAACTCGG AGGAATCGAG GGTGGAGTCG ACGGCCGACG ACCTGGGGGA CGCGCTACCC 
GGTGGGGCGG CGGTGGCGGC CGTCCCGGAC GCAGCCCGGC GAGAGCCATA CGGCCACCTG 
GGGCCCGCAG AGCTGCTGGA GGCCTCGCCC GCCGCGCGCT CCCTGCAGAC CCCGTCGGCG 
CGCCTGGTGC CCGCTTCCGC GCCGCCCGCG CGCCTGGTGG AGGTGCCCGC CGCGCCGGTC 
CGGGTGGTGG AGACCTCGGC CCTGCTGTGC ACCGCGCAAC ACTTAGCGGC CGTCCAGTCG 
TCCGGGGCCC CTGCGACGGC GTCGGGGCCG CAGGTGGATA ACACGGGTGG GGAGCCGGCC 
TGGGACTCCC CGCTGCGGCG CGTCTTGGCC GAGCTGAACC GCATCCCCAG CAGCCGGCGG 
CGAGCGGCCC GCCTCTTTGA GTGGCTCATC GCGCCCATGC CGCCAGATCA CTTTTACCGG 
CGCCTATGGG AGCGCGAGGC GGTGCTGGTG CGGCGGCAGG ACCACACCTA CTACCAGGGA 
CTTTTCTCTA CCGCTGACCT GGATTCGATG CTGCGCAACG AGGAGGTGCA GTTCGGCCAG 
CATTTGGACG CCGCTCGCTA CATCAACGGA CGACGCGAGA CCCTGAACCC ACCCGGCCGC 
GCGCTGCCCG CCGCCGCGTG GTCCCTGTAC CAGGCCGGCT GCTCCCTGCG TCTCCTCTGT 
CCGCAGGCTT TCTCTACTAC TGTGTGGCAG TTTTTGGCTG TGCTTCAAGA GCAGTTTGGA 
AGCATGGCAG GCTCCAACGT TTACCTCACG CCCCCTAACT CGCAGGGCTT TGCCCCCCAC 
TACGACGACA TCGAGGCCTT CGTGCTGCAG CTGGAAGGTA GGAAACTCTG GCGTGTATAC 
CGACCCCGAG TCCCAACCGA GGAACTGGCT CTGACATCCA GCCCCAACTT CAGTCAGGAC 
GACCTCGGTG AGCCGGTGCT GCAGACCGTG CTGGAACCTG GAGATTTGCT GTATTTTCCT 
CGGGGCTTCA TTCACCAAGC TGAATGCCAG GATGGAGTCC ACTCTCTGCA CCTCACCTTG 
TCCACGTACC AGCGCAATAC CTGGGGTGAC TTCTTAGAGG CCATACTGCC TCTGGCAGTG 
CAGGCTGCAA TGGAAGAAAA TGTGGAGTTT CGGAGGGGTC TGCCCCGAGA CTTCATGGAT 
TACATGGGGG CCCAGCATTC AGATTCTAAG GATCCGCGAA GAACCGCTTT CATGGAGAAG 
GTGCGGGTCT TGGTTGCCCG CCTGGGACAC TTTGCTCCTG TTGATGCTGT GGCCGACCAG 
CGAGCCAAAG ACTTCATTCA CGATTCTCTG CCCCCTGTTT TGACTGATAG GGAGAGGGCA 
CTAAGTGTTT ACGGGCTTCC AATTCGCTGG GAGGCTGGAG AACCTGTAAA CGTGGGGGCC 
CAGTTGACAA CAGAAACAGA AGTCCATATG CTTCAGGATG GGATAGCTCG GCTGGTGGGT 
GAGGGGGGCC ATTTGTTTCT CTATTACACA GTGGAAAACT CCCGTGTGTA TCATCTGGAA 
GAACCCAAGT GCTTGGAAAT ATACCCCCAG CAAGCTGATG CCATGGAACT GTTGCTTGGT 
TCTTATCCAG AGTTTGTGAG AGTGGGGGAC CTGCCCTGTG ACAGTGTGGA GGACCAGCTG 
TCCTTGGCAA CCACGTTGTA TGATAAGGGG CTGCTGCTCA CTAAGATGCC TCTAGCCCTA 
AATTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RIOX1 ( NM_024644.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_078920.2 Homo sapiens ribosomal oxygenase 1 (RIOX1), mRNA.

Price & Availability↑

CloneID	OHu01455
Clone ID Related Accession (Same CDS sequence)	NM_024644.4 , NM_024644.5
Accession Version	NM_024644.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1926bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-01
Organism	Homo sapiens(human)
Product	ribosomal oxygenase 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC005280.5, HY178771.1, DA872764.1, DA509240.1, BC071954.1, CN259773.1 and BX390965.1. On May 17, 2019 this sequence version replaced NM_024644.4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript is intronless :: BC011350.1, AY390535.1 [ECO:0000345] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000304061.8/ ENSP00000477507.1 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGATGGGC TCCAGGCCAG TGCAGGGCCG TTGAGGCGCG GGCGGCCGAA GCGCCGGCGC 
AAGCCCCAGC CACACAGCGG GTCGGTCCTG GCCCTGCCCT TGAGGTCCAG GAAGATACGA 
AAGCAGCTGC GAAGTGTTGT ATCCCGCATG GCAGCGCTGA GGACGCAGAC GCTGCCTAGC 
GAGAACTCGG AGGAATCGAG GGTGGAGTCG ACGGCCGACG ACCTGGGGGA CGCGCTACCC 
GGTGGGGCGG CGGTGGCGGC CGTCCCGGAC GCAGCCCGGC GAGAGCCATA CGGCCACCTG 
GGGCCCGCAG AGCTGCTGGA GGCCTCGCCC GCCGCGCGCT CCCTGCAGAC CCCGTCGGCG 
CGCCTGGTGC CCGCTTCCGC GCCGCCCGCG CGCCTGGTGG AGGTGCCCGC CGCGCCGGTC 
CGGGTGGTGG AGACCTCGGC CCTGCTGTGC ACCGCGCAAC ACTTAGCGGC CGTCCAGTCG 
TCCGGGGCCC CTGCGACGGC GTCGGGGCCG CAGGTGGATA ACACGGGTGG GGAGCCGGCC 
TGGGACTCCC CGCTGCGGCG CGTCTTGGCC GAGCTGAACC GCATCCCCAG CAGCCGGCGG 
CGAGCGGCCC GCCTCTTTGA GTGGCTCATC GCGCCCATGC CGCCAGATCA CTTTTACCGG 
CGCCTATGGG AGCGCGAGGC GGTGCTGGTG CGGCGGCAGG ACCACACCTA CTACCAGGGA 
CTTTTCTCTA CCGCTGACCT GGATTCGATG CTGCGCAACG AGGAGGTGCA GTTCGGCCAG 
CATTTGGACG CCGCTCGCTA CATCAACGGA CGACGCGAGA CCCTGAACCC ACCCGGCCGC 
GCGCTGCCCG CCGCCGCGTG GTCCCTGTAC CAGGCCGGCT GCTCCCTGCG TCTCCTCTGT 
CCGCAGGCTT TCTCTACTAC TGTGTGGCAG TTTTTGGCTG TGCTTCAAGA GCAGTTTGGA 
AGCATGGCAG GCTCCAACGT TTACCTCACG CCCCCTAACT CGCAGGGCTT TGCCCCCCAC 
TACGACGACA TCGAGGCCTT CGTGCTGCAG CTGGAAGGTA GGAAACTCTG GCGTGTATAC 
CGACCCCGAG TCCCAACCGA GGAACTGGCT CTGACATCCA GCCCCAACTT CAGTCAGGAC 
GACCTCGGTG AGCCGGTGCT GCAGACCGTG CTGGAACCTG GAGATTTGCT GTATTTTCCT 
CGGGGCTTCA TTCACCAAGC TGAATGCCAG GATGGAGTCC ACTCTCTGCA CCTCACCTTG 
TCCACGTACC AGCGCAATAC CTGGGGTGAC TTCTTAGAGG CCATACTGCC TCTGGCAGTG 
CAGGCTGCAA TGGAAGAAAA TGTGGAGTTT CGGAGGGGTC TGCCCCGAGA CTTCATGGAT 
TACATGGGGG CCCAGCATTC AGATTCTAAG GATCCGCGAA GAACCGCTTT CATGGAGAAG 
GTGCGGGTCT TGGTTGCCCG CCTGGGACAC TTTGCTCCTG TTGATGCTGT GGCCGACCAG 
CGAGCCAAAG ACTTCATTCA CGATTCTCTG CCCCCTGTTT TGACTGATAG GGAGAGGGCA 
CTAAGTGTTT ACGGGCTTCC AATTCGCTGG GAGGCTGGAG AACCTGTAAA CGTGGGGGCC 
CAGTTGACAA CAGAAACAGA AGTCCATATG CTTCAGGATG GGATAGCTCG GCTGGTGGGT 
GAGGGGGGCC ATTTGTTTCT CTATTACACA GTGGAAAACT CCCGTGTGTA TCATCTGGAA 
GAACCCAAGT GCTTGGAAAT ATACCCCCAG CAAGCTGATG CCATGGAACT GTTGCTTGGT 
TCTTATCCAG AGTTTGTGAG AGTGGGGGAC CTGCCCTGTG ACAGTGTGGA GGACCAGCTG 
TCCTTGGCAA CCACGTTGTA TGATAAGGGG CTGCTGCTCA CTAAGATGCC TCTAGCCCTA 
AATTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_078920.2
CDS	86..2011
Translation	MDGLQASAGPLRRGRPKRRRKPQPHSGSVLALPLRSRKIRKQLRSVVSRMAALRTQTLPSENSEESRVESTADDLGDALPGGAAVAAVPDAARREPYGHLGPAELLEASPAARSLQTPSARLVPASAPPARLVEVPAAPVRVVETSALLCTAQHLAAVQSSGAPATASGPQVDNTGGEPAWDSPLRRVLAELNRIPSSRRRAARLFEWLIAPMPPDHFYRRLWEREAVLVRRQDHTYYQGLFSTADLDSMLRNEEVQFGQHLDAARYINGRRETLNPPGRALPAAAWSLYQAGCSLRLLCPQAFSTTVWQFLAVLQEQFGSMAGSNVYLTPPNSQGFAPHYDDIEAFVLQLEGRKLWRVYRPRVPTEELALTSSPNFSQDDLGEPVLQTVLEPGDLLYFPRGFIHQAECQDGVHSLHLTLSTYQRNTWGDFLEAILPLAVQAAMEENVEFRRGLPRDFMDYMGAQHSDSKDPRRTAFMEKVRVLVARLGHFAPVDAVADQRAKDFIHDSLPPVLTDRERALSVYGLPIRWEAGEPVNVGAQLTTETEVHMLQDGIARLVGEGGHLFLYYTVENSRVYHLEEPKCLEIYPQQADAMELLLGSYPEFVRVGDLPCDSVEDQLSLATTLYDKGLLLTKMPLALN

Target ORF information:

RefSeq Version	NM_024644.5
Organism	Homo sapiens(human)
Definition	Homo sapiens ribosomal oxygenase 1 (RIOX1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_024644.5

ORF Insert Sequence:

ATGGATGGGC TCCAGGCCAG TGCAGGGCCG TTGAGGCGCG GGCGGCCGAA GCGCCGGCGC 
AAGCCCCAGC CACACAGCGG GTCGGTCCTG GCCCTGCCCT TGAGGTCCAG GAAGATACGA 
AAGCAGCTGC GAAGTGTTGT ATCCCGCATG GCAGCGCTGA GGACGCAGAC GCTGCCTAGC 
GAGAACTCGG AGGAATCGAG GGTGGAGTCG ACGGCCGACG ACCTGGGGGA CGCGCTACCC 
GGTGGGGCGG CGGTGGCGGC CGTCCCGGAC GCAGCCCGGC GAGAGCCATA CGGCCACCTG 
GGGCCCGCAG AGCTGCTGGA GGCCTCGCCC GCCGCGCGCT CCCTGCAGAC CCCGTCGGCG 
CGCCTGGTGC CCGCTTCCGC GCCGCCCGCG CGCCTGGTGG AGGTGCCCGC CGCGCCGGTC 
CGGGTGGTGG AGACCTCGGC CCTGCTGTGC ACCGCGCAAC ACTTAGCGGC CGTCCAGTCG 
TCCGGGGCCC CTGCGACGGC GTCGGGGCCG CAGGTGGATA ACACGGGTGG GGAGCCGGCC 
TGGGACTCCC CGCTGCGGCG CGTCTTGGCC GAGCTGAACC GCATCCCCAG CAGCCGGCGG 
CGAGCGGCCC GCCTCTTTGA GTGGCTCATC GCGCCCATGC CGCCAGATCA CTTTTACCGG 
CGCCTATGGG AGCGCGAGGC GGTGCTGGTG CGGCGGCAGG ACCACACCTA CTACCAGGGA 
CTTTTCTCTA CCGCTGACCT GGATTCGATG CTGCGCAACG AGGAGGTGCA GTTCGGCCAG 
CATTTGGACG CCGCTCGCTA CATCAACGGA CGACGCGAGA CCCTGAACCC ACCCGGCCGC 
GCGCTGCCCG CCGCCGCGTG GTCCCTGTAC CAGGCCGGCT GCTCCCTGCG TCTCCTCTGT 
CCGCAGGCTT TCTCTACTAC TGTGTGGCAG TTTTTGGCTG TGCTTCAAGA GCAGTTTGGA 
AGCATGGCAG GCTCCAACGT TTACCTCACG CCCCCTAACT CGCAGGGCTT TGCCCCCCAC 
TACGACGACA TCGAGGCCTT CGTGCTGCAG CTGGAAGGTA GGAAACTCTG GCGTGTATAC 
CGACCCCGAG TCCCAACCGA GGAACTGGCT CTGACATCCA GCCCCAACTT CAGTCAGGAC 
GACCTCGGTG AGCCGGTGCT GCAGACCGTG CTGGAACCTG GAGATTTGCT GTATTTTCCT 
CGGGGCTTCA TTCACCAAGC TGAATGCCAG GATGGAGTCC ACTCTCTGCA CCTCACCTTG 
TCCACGTACC AGCGCAATAC CTGGGGTGAC TTCTTAGAGG CCATACTGCC TCTGGCAGTG 
CAGGCTGCAA TGGAAGAAAA TGTGGAGTTT CGGAGGGGTC TGCCCCGAGA CTTCATGGAT 
TACATGGGGG CCCAGCATTC AGATTCTAAG GATCCGCGAA GAACCGCTTT CATGGAGAAG 
GTGCGGGTCT TGGTTGCCCG CCTGGGACAC TTTGCTCCTG TTGATGCTGT GGCCGACCAG 
CGAGCCAAAG ACTTCATTCA CGATTCTCTG CCCCCTGTTT TGACTGATAG GGAGAGGGCA 
CTAAGTGTTT ACGGGCTTCC AATTCGCTGG GAGGCTGGAG AACCTGTAAA CGTGGGGGCC 
CAGTTGACAA CAGAAACAGA AGTCCATATG CTTCAGGATG GGATAGCTCG GCTGGTGGGT 
GAGGGGGGCC ATTTGTTTCT CTATTACACA GTGGAAAACT CCCGTGTGTA TCATCTGGAA 
GAACCCAAGT GCTTGGAAAT ATACCCCCAG CAAGCTGATG CCATGGAACT GTTGCTTGGT 
TCTTATCCAG AGTTTGTGAG AGTGGGGGAC CTGCCCTGTG ACAGTGTGGA GGACCAGCTG 
TCCTTGGCAA CCACGTTGTA TGATAAGGGG CTGCTGCTCA CTAAGATGCC TCTAGCCCTA 
AATTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Clinical Significance of Histone Demethylase NO66 in Invasive Colorectal Cancer.
Annals of surgical oncology24(3)841-849(2017 Mar)
Nishizawa Y,Nishida N,Konno M,Kawamoto K,Asai A,Koseki J,Takahashi H,Haraguchi N,Nishimura J,Hata T,Matsuda C,Mizushima T,Satoh T,Doki Y,Mori M,Ishii H

Structure-function relationships of human JmjC oxygenases-demethylases versus hydroxylases.
Current opinion in structural biology4162-72(2016 Dec)
Markolovic S,Leissing TM,Chowdhury R,Wilkins SE,Lu X,Schofield CJ

Expression of histone methyltransferases as novel biomarkers for renal cell tumor diagnosis and prognostication.
Epigenetics10(11)1033-43(2015)
Pires-Lu?s AS,Vieira-Coimbra M,Vieira FQ,Costa-Pinheiro P,Silva-Santos R,Dias PC,Antunes L,Lobo F,Oliveira J,Gon?alves CS,Costa BM,Henrique R,Jer?nimo C

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RIOX1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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