Dkk3 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Gene Symbol	Dkk3
Entrez Gene ID	171548
Full Name	dickkopf WNT signaling pathway inhibitor 3
Synonyms	Reic,p29
General protein information	Preferred Names dickkopf WNT signaling pathway inhibitor 3 Names dickkopf-related protein 3 dickkopf 3 homolog dickkopf homolog 3
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 1 Map Location: 1q33

mRNA and Protein(s)

mRNA	Protein	Name
NM_138519.2	NP_612528.2	dickkopf-related protein 3 precursor
XM_017588739.1	XP_017444228.1	dickkopf-related protein 3 isoform X1
XM_006230009.3	XP_006230071.1	dickkopf-related protein 3 isoform X1

Pathways from BioSystems

Homologies

Bos taurus (cattle)	DKK3	NP_001093776.1
Pan troglodytes (chimpanzee)	DKK3	XP_001171316.1
	DKK3	XP_001097713.1
Rattus norvegicus (Norway rat)	Dkk3	NP_612528.2
Danio rerio (zebrafish)	dkk3b	NP_001152755.1
Homo sapiens (human)	DKK3	NP_056965.3
Danio rerio (zebrafish)	dkk3	NP_001083014.1
Canis lupus familiaris (dog)	DKK3	XP_534060.3
Mus musculus (house mouse)	Dkk3	NP_056629.1
Gallus gallus (chicken)	DKK3	NP_990456.1

Gene Ontology
Bibliography

Related articles in PubMed

Dickkopf-related protein 3 negatively regulates the osteogenic differentiation of rat dental follicle cells.
Zhang X, Du Y, Ling J, Li W, Liao Y, Wei X
Molecular medicine reports15(4)1673-1681(2017 Apr)

Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.
Abonnenc M, Nabeebaccus AA, Mayr U, Barallobre-Barreiro J, Dong X, Cuello F, Sur S, Drozdov I, Langley SR, Lu R, Stathopoulou K, Didangelos A, Yin X, Zimmermann WH, Shah AM, Zampetaki A, Mayr M
Circulation research113(10)1138-47(2013 Oct)

Adenovirus-delivered DKK3/WNT4 and steroidogenesis in primary cultures of adrenocortical cells.
Chen M, Hornsby PJ
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme38(9)549-55(2006 Sep)

Functional characterization of WNT7A signaling in PC12 cells: interaction with A FZD5 x LRP6 receptor complex and modulation by Dickkopf proteins.
Caricasole A, Ferraro T, Iacovelli L, Barletta E, Caruso A, Melchiorri D, Terstappen GC, Nicoletti F
The Journal of biological chemistry278(39)37024-31(2003 Sep)

Zonal expression of dickkopf-3 and components of the Wnt signalling pathways in the human adrenal cortex.
Suwa T, Chen M, Hawks CL, Hornsby PJ
The Journal of endocrinology178(1)149-58(2003 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

DKK3 expression negatively regulates the osteogenic differentiation of dental follicle cells.
Title: Dickkopf-related protein 3 negatively regulates the osteogenic differentiation of rat dental follicle cells.

WNT7A can specifically act via a Frizzled-5.LRP6 receptor complex in PC12 cells and that this activity can be antagonized by Dickkopf-1 and Dickkopf-3.
Title: Functional characterization of WNT7A signaling in PC12 cells: interaction with A FZD5 x LRP6 receptor complex and modulation by Dickkopf proteins.

data do not support that thyroxine-binding protein p29 has a functional relationship with D2, but expression of p29 in the blood-CSF barrier suggests that it might be involved in T(4) transport to and from the CSF
Title: Divergent expression of type 2 deiodinase and the putative thyroxine-binding protein p29, in rat brain, suggests that they are functionally unrelated proteins.

The following Dkk3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Dkk3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa01537	NM_138519.2 Latest version!	Rattus norvegicus dickkopf WNT signaling pathway inhibitor 3 (Dkk3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$188.30 $269.00
ORa01537	XM_017588739.1 Latest version!	Rattus norvegicus dickkopf WNT signaling pathway inhibitor 3 (Dkk3), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$188.30 $269.00
ORa01537	XM_006230009.3 Latest version!	Rattus norvegicus dickkopf WNT signaling pathway inhibitor 3 (Dkk3), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$188.30 $269.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Dkk3 ( NM_138519.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_612528.2 Rattus norvegicus dickkopf WNT signaling pathway inhibitor 3 (Dkk3), mRNA.

Price & Availability↑

CloneID	ORa01537
Clone ID Related Accession (Same CDS sequence)	NM_138519.2 , XM_017588739.1 , XM_006230009.3
Accession Version	NM_138519.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1047bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-30
Organism	Rattus norvegicus(Norway rat)
Product	dickkopf-related protein 3 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC160821.1 and AABR07005037.1. On Sep 12, 2012 this sequence version replaced NM_138519.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: BC160821.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGCAGTGGC TCCGGGATAT TTTGCTGTGT ATGCTGCTAG CGGCGGTGGT CCCCACTGCC 
CCCACTCCTG CCCCGACGGC CACTTGGACT CCGGCAGAGC CGGGCCCGGC TCTTAACTAC 
CCTCAGGAGG AAGCTACGCT CAATGAGATG TTCCGAGAGG TAGAGGAGCT GATGGAAGAC 
ACTCAGCACA AACTGCGCAG CGCGGTGGAG GAGATGGAGG CGGAAGAAGC GGCTGCTAGA 
ACGTCCTCTG AGGTGACCCT GTCAAGTTTA CCTGCCAACT ACCACAACGA GACCAACACG 
GAGACCAGGA TGGAAAATAA CACAGCCCAT GTGCACCGGG AGGTTCACAA GATAACCAAC 
AACCAGAGTG GACAGACGGT CTTTTCTGAG ACAGTCATTA CATCTGTAGA GGATGGAGAA 
GGCAAGAAGA GCCATGAATG TATCATTGAT GAGGACTGCG GACCCACCAG GTACTGCCAG 
TTCTCCAGCT TCAAGTATAC CTGCCAGCCG TGCCGGGACC AGCAGATGCT ATGCACCCGA 
GACAGTGAGT GCTGTGGAGA CCAGCTTTGT GCCTGGGGTC ACTGCACCCA AAAGGCCACC 
AAAGGTAGCA ATGGGACCAT CTGTGACAAC CAGAGGGATT GCCAGCCTGG CCTGTGCTGC 
GCCTTCCAAA GAGGCCTGCT GTTCCCTGTG TGCACACCCC TGCCCGTGGA GGGGGAGCTC 
TGTCATGACC CCACCAGCCA GATGCTGGAC CTCATCACCT GGGAACTGGA GCCTGAAGGC 
GCTTTGGACC GATGCCCCTG TGCCAGTGGC CTCCTCTGCC AGCCACACAG CCACAGTCTG 
GTATACATGT GCAAGCCAGC CTTCGTTGGC AGCCATGACC ACAATGAGGA GAGCCAGCTG 
CCCAGGGAGG CCCTGGATGA CTACGAAGAT GTTGGCTTCA TAGGGGAGGT GCGTCAGGAG 
CTGGAAGACC TGGAGCGGAG CCTGGCCCAG GAGATGGCAT TTGAGGAGGC CACCCCTGTG 
GATTCACTAG GTGGAGAGAA GATTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_612528.2
CDS	142..1188
Translation	MQWLRDILLCMLLAAVVPTAPTPAPTATWTPAEPGPALNYPQEEATLNEMFREVEELMEDTQHKLRSAVEEMEAEEAAARTSSEVTLSSLPANYHNETNTETRMENNTAHVHREVHKITNNQSGQTVFSETVITSVEDGEGKKSHECIIDEDCGPTRYCQFSSFKYTCQPCRDQQMLCTRDSECCGDQLCAWGHCTQKATKGSNGTICDNQRDCQPGLCCAFQRGLLFPVCTPLPVEGELCHDPTSQMLDLITWELEPEGALDRCPCASGLLCQPHSHSLVYMCKPAFVGSHDHNEESQLPREALDDYEDVGFIGEVRQELEDLERSLAQEMAFEEATPVDSLGGEKI

Target ORF information:

RefSeq Version	NM_138519.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus dickkopf WNT signaling pathway inhibitor 3 (Dkk3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_138519.2

ORF Insert Sequence:

ATGCAGTGGC TCCGGGATAT TTTGCTGTGT ATGCTGCTAG CGGCGGTGGT CCCCACTGCC 
CCCACTCCTG CCCCGACGGC CACTTGGACT CCGGCAGAGC CGGGCCCGGC TCTTAACTAC 
CCTCAGGAGG AAGCTACGCT CAATGAGATG TTCCGAGAGG TAGAGGAGCT GATGGAAGAC 
ACTCAGCACA AACTGCGCAG CGCGGTGGAG GAGATGGAGG CGGAAGAAGC GGCTGCTAGA 
ACGTCCTCTG AGGTGACCCT GTCAAGTTTA CCTGCCAACT ACCACAACGA GACCAACACG 
GAGACCAGGA TGGAAAATAA CACAGCCCAT GTGCACCGGG AGGTTCACAA GATAACCAAC 
AACCAGAGTG GACAGACGGT CTTTTCTGAG ACAGTCATTA CATCTGTAGA GGATGGAGAA 
GGCAAGAAGA GCCATGAATG TATCATTGAT GAGGACTGCG GACCCACCAG GTACTGCCAG 
TTCTCCAGCT TCAAGTATAC CTGCCAGCCG TGCCGGGACC AGCAGATGCT ATGCACCCGA 
GACAGTGAGT GCTGTGGAGA CCAGCTTTGT GCCTGGGGTC ACTGCACCCA AAAGGCCACC 
AAAGGTAGCA ATGGGACCAT CTGTGACAAC CAGAGGGATT GCCAGCCTGG CCTGTGCTGC 
GCCTTCCAAA GAGGCCTGCT GTTCCCTGTG TGCACACCCC TGCCCGTGGA GGGGGAGCTC 
TGTCATGACC CCACCAGCCA GATGCTGGAC CTCATCACCT GGGAACTGGA GCCTGAAGGC 
GCTTTGGACC GATGCCCCTG TGCCAGTGGC CTCCTCTGCC AGCCACACAG CCACAGTCTG 
GTATACATGT GCAAGCCAGC CTTCGTTGGC AGCCATGACC ACAATGAGGA GAGCCAGCTG 
CCCAGGGAGG CCCTGGATGA CTACGAAGAT GTTGGCTTCA TAGGGGAGGT GCGTCAGGAG 
CTGGAAGACC TGGAGCGGAG CCTGGCCCAG GAGATGGCAT TTGAGGAGGC CACCCCTGTG 
GATTCACTAG GTGGAGAGAA GATTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Dkk3 ( XM_017588739.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017444228.1 Rattus norvegicus dickkopf WNT signaling pathway inhibitor 3 (Dkk3), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa01537
Clone ID Related Accession (Same CDS sequence)	NM_138519.2 , XM_017588739.1 , XM_006230009.3
Accession Version	XM_017588739.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1047bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	dickkopf-related protein 3 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCAGTGGC TCCGGGATAT TTTGCTGTGT ATGCTGCTAG CGGCGGTGGT CCCCACTGCC 
CCCACTCCTG CCCCGACGGC CACTTGGACT CCGGCAGAGC CGGGCCCGGC TCTTAACTAC 
CCTCAGGAGG AAGCTACGCT CAATGAGATG TTCCGAGAGG TAGAGGAGCT GATGGAAGAC 
ACTCAGCACA AACTGCGCAG CGCGGTGGAG GAGATGGAGG CGGAAGAAGC GGCTGCTAGA 
ACGTCCTCTG AGGTGACCCT GTCAAGTTTA CCTGCCAACT ACCACAACGA GACCAACACG 
GAGACCAGGA TGGAAAATAA CACAGCCCAT GTGCACCGGG AGGTTCACAA GATAACCAAC 
AACCAGAGTG GACAGACGGT CTTTTCTGAG ACAGTCATTA CATCTGTAGA GGATGGAGAA 
GGCAAGAAGA GCCATGAATG TATCATTGAT GAGGACTGCG GACCCACCAG GTACTGCCAG 
TTCTCCAGCT TCAAGTATAC CTGCCAGCCG TGCCGGGACC AGCAGATGCT ATGCACCCGA 
GACAGTGAGT GCTGTGGAGA CCAGCTTTGT GCCTGGGGTC ACTGCACCCA AAAGGCCACC 
AAAGGTAGCA ATGGGACCAT CTGTGACAAC CAGAGGGATT GCCAGCCTGG CCTGTGCTGC 
GCCTTCCAAA GAGGCCTGCT GTTCCCTGTG TGCACACCCC TGCCCGTGGA GGGGGAGCTC 
TGTCATGACC CCACCAGCCA GATGCTGGAC CTCATCACCT GGGAACTGGA GCCTGAAGGC 
GCTTTGGACC GATGCCCCTG TGCCAGTGGC CTCCTCTGCC AGCCACACAG CCACAGTCTG 
GTATACATGT GCAAGCCAGC CTTCGTTGGC AGCCATGACC ACAATGAGGA GAGCCAGCTG 
CCCAGGGAGG CCCTGGATGA CTACGAAGAT GTTGGCTTCA TAGGGGAGGT GCGTCAGGAG 
CTGGAAGACC TGGAGCGGAG CCTGGCCCAG GAGATGGCAT TTGAGGAGGC CACCCCTGTG 
GATTCACTAG GTGGAGAGAA GATTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017444228.1
CDS	166..1212
Translation	MQWLRDILLCMLLAAVVPTAPTPAPTATWTPAEPGPALNYPQEEATLNEMFREVEELMEDTQHKLRSAVEEMEAEEAAARTSSEVTLSSLPANYHNETNTETRMENNTAHVHREVHKITNNQSGQTVFSETVITSVEDGEGKKSHECIIDEDCGPTRYCQFSSFKYTCQPCRDQQMLCTRDSECCGDQLCAWGHCTQKATKGSNGTICDNQRDCQPGLCCAFQRGLLFPVCTPLPVEGELCHDPTSQMLDLITWELEPEGALDRCPCASGLLCQPHSHSLVYMCKPAFVGSHDHNEESQLPREALDDYEDVGFIGEVRQELEDLERSLAQEMAFEEATPVDSLGGEKI

Target ORF information:

RefSeq Version	XM_017588739.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus dickkopf WNT signaling pathway inhibitor 3 (Dkk3), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017588739.1

ORF Insert Sequence:

ATGCAGTGGC TCCGGGATAT TTTGCTGTGT ATGCTGCTAG CGGCGGTGGT CCCCACTGCC 
CCCACTCCTG CCCCGACGGC CACTTGGACT CCGGCAGAGC CGGGCCCGGC TCTTAACTAC 
CCTCAGGAGG AAGCTACGCT CAATGAGATG TTCCGAGAGG TAGAGGAGCT GATGGAAGAC 
ACTCAGCACA AACTGCGCAG CGCGGTGGAG GAGATGGAGG CGGAAGAAGC GGCTGCTAGA 
ACGTCCTCTG AGGTGACCCT GTCAAGTTTA CCTGCCAACT ACCACAACGA GACCAACACG 
GAGACCAGGA TGGAAAATAA CACAGCCCAT GTGCACCGGG AGGTTCACAA GATAACCAAC 
AACCAGAGTG GACAGACGGT CTTTTCTGAG ACAGTCATTA CATCTGTAGA GGATGGAGAA 
GGCAAGAAGA GCCATGAATG TATCATTGAT GAGGACTGCG GACCCACCAG GTACTGCCAG 
TTCTCCAGCT TCAAGTATAC CTGCCAGCCG TGCCGGGACC AGCAGATGCT ATGCACCCGA 
GACAGTGAGT GCTGTGGAGA CCAGCTTTGT GCCTGGGGTC ACTGCACCCA AAAGGCCACC 
AAAGGTAGCA ATGGGACCAT CTGTGACAAC CAGAGGGATT GCCAGCCTGG CCTGTGCTGC 
GCCTTCCAAA GAGGCCTGCT GTTCCCTGTG TGCACACCCC TGCCCGTGGA GGGGGAGCTC 
TGTCATGACC CCACCAGCCA GATGCTGGAC CTCATCACCT GGGAACTGGA GCCTGAAGGC 
GCTTTGGACC GATGCCCCTG TGCCAGTGGC CTCCTCTGCC AGCCACACAG CCACAGTCTG 
GTATACATGT GCAAGCCAGC CTTCGTTGGC AGCCATGACC ACAATGAGGA GAGCCAGCTG 
CCCAGGGAGG CCCTGGATGA CTACGAAGAT GTTGGCTTCA TAGGGGAGGT GCGTCAGGAG 
CTGGAAGACC TGGAGCGGAG CCTGGCCCAG GAGATGGCAT TTGAGGAGGC CACCCCTGTG 
GATTCACTAG GTGGAGAGAA GATTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Dkk3 ( XM_006230009.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006230071.1 Rattus norvegicus dickkopf WNT signaling pathway inhibitor 3 (Dkk3), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa01537
Clone ID Related Accession (Same CDS sequence)	NM_138519.2 , XM_017588739.1 , XM_006230009.3
Accession Version	XM_006230009.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1047bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	dickkopf-related protein 3 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006230009.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCAGTGGC TCCGGGATAT TTTGCTGTGT ATGCTGCTAG CGGCGGTGGT CCCCACTGCC 
CCCACTCCTG CCCCGACGGC CACTTGGACT CCGGCAGAGC CGGGCCCGGC TCTTAACTAC 
CCTCAGGAGG AAGCTACGCT CAATGAGATG TTCCGAGAGG TAGAGGAGCT GATGGAAGAC 
ACTCAGCACA AACTGCGCAG CGCGGTGGAG GAGATGGAGG CGGAAGAAGC GGCTGCTAGA 
ACGTCCTCTG AGGTGACCCT GTCAAGTTTA CCTGCCAACT ACCACAACGA GACCAACACG 
GAGACCAGGA TGGAAAATAA CACAGCCCAT GTGCACCGGG AGGTTCACAA GATAACCAAC 
AACCAGAGTG GACAGACGGT CTTTTCTGAG ACAGTCATTA CATCTGTAGA GGATGGAGAA 
GGCAAGAAGA GCCATGAATG TATCATTGAT GAGGACTGCG GACCCACCAG GTACTGCCAG 
TTCTCCAGCT TCAAGTATAC CTGCCAGCCG TGCCGGGACC AGCAGATGCT ATGCACCCGA 
GACAGTGAGT GCTGTGGAGA CCAGCTTTGT GCCTGGGGTC ACTGCACCCA AAAGGCCACC 
AAAGGTAGCA ATGGGACCAT CTGTGACAAC CAGAGGGATT GCCAGCCTGG CCTGTGCTGC 
GCCTTCCAAA GAGGCCTGCT GTTCCCTGTG TGCACACCCC TGCCCGTGGA GGGGGAGCTC 
TGTCATGACC CCACCAGCCA GATGCTGGAC CTCATCACCT GGGAACTGGA GCCTGAAGGC 
GCTTTGGACC GATGCCCCTG TGCCAGTGGC CTCCTCTGCC AGCCACACAG CCACAGTCTG 
GTATACATGT GCAAGCCAGC CTTCGTTGGC AGCCATGACC ACAATGAGGA GAGCCAGCTG 
CCCAGGGAGG CCCTGGATGA CTACGAAGAT GTTGGCTTCA TAGGGGAGGT GCGTCAGGAG 
CTGGAAGACC TGGAGCGGAG CCTGGCCCAG GAGATGGCAT TTGAGGAGGC CACCCCTGTG 
GATTCACTAG GTGGAGAGAA GATTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006230071.1
CDS	162..1208
Translation	MQWLRDILLCMLLAAVVPTAPTPAPTATWTPAEPGPALNYPQEEATLNEMFREVEELMEDTQHKLRSAVEEMEAEEAAARTSSEVTLSSLPANYHNETNTETRMENNTAHVHREVHKITNNQSGQTVFSETVITSVEDGEGKKSHECIIDEDCGPTRYCQFSSFKYTCQPCRDQQMLCTRDSECCGDQLCAWGHCTQKATKGSNGTICDNQRDCQPGLCCAFQRGLLFPVCTPLPVEGELCHDPTSQMLDLITWELEPEGALDRCPCASGLLCQPHSHSLVYMCKPAFVGSHDHNEESQLPREALDDYEDVGFIGEVRQELEDLERSLAQEMAFEEATPVDSLGGEKI

Target ORF information:

RefSeq Version	XM_006230009.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus dickkopf WNT signaling pathway inhibitor 3 (Dkk3), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006230009.3

ORF Insert Sequence:

ATGCAGTGGC TCCGGGATAT TTTGCTGTGT ATGCTGCTAG CGGCGGTGGT CCCCACTGCC 
CCCACTCCTG CCCCGACGGC CACTTGGACT CCGGCAGAGC CGGGCCCGGC TCTTAACTAC 
CCTCAGGAGG AAGCTACGCT CAATGAGATG TTCCGAGAGG TAGAGGAGCT GATGGAAGAC 
ACTCAGCACA AACTGCGCAG CGCGGTGGAG GAGATGGAGG CGGAAGAAGC GGCTGCTAGA 
ACGTCCTCTG AGGTGACCCT GTCAAGTTTA CCTGCCAACT ACCACAACGA GACCAACACG 
GAGACCAGGA TGGAAAATAA CACAGCCCAT GTGCACCGGG AGGTTCACAA GATAACCAAC 
AACCAGAGTG GACAGACGGT CTTTTCTGAG ACAGTCATTA CATCTGTAGA GGATGGAGAA 
GGCAAGAAGA GCCATGAATG TATCATTGAT GAGGACTGCG GACCCACCAG GTACTGCCAG 
TTCTCCAGCT TCAAGTATAC CTGCCAGCCG TGCCGGGACC AGCAGATGCT ATGCACCCGA 
GACAGTGAGT GCTGTGGAGA CCAGCTTTGT GCCTGGGGTC ACTGCACCCA AAAGGCCACC 
AAAGGTAGCA ATGGGACCAT CTGTGACAAC CAGAGGGATT GCCAGCCTGG CCTGTGCTGC 
GCCTTCCAAA GAGGCCTGCT GTTCCCTGTG TGCACACCCC TGCCCGTGGA GGGGGAGCTC 
TGTCATGACC CCACCAGCCA GATGCTGGAC CTCATCACCT GGGAACTGGA GCCTGAAGGC 
GCTTTGGACC GATGCCCCTG TGCCAGTGGC CTCCTCTGCC AGCCACACAG CCACAGTCTG 
GTATACATGT GCAAGCCAGC CTTCGTTGGC AGCCATGACC ACAATGAGGA GAGCCAGCTG 
CCCAGGGAGG CCCTGGATGA CTACGAAGAT GTTGGCTTCA TAGGGGAGGT GCGTCAGGAG 
CTGGAAGACC TGGAGCGGAG CCTGGCCCAG GAGATGGCAT TTGAGGAGGC CACCCCTGTG 
GATTCACTAG GTGGAGAGAA GATTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Dickkopf-related protein 3 negatively regulates the osteogenic differentiation of rat dental follicle cells.
Molecular medicine reports15(4)1673-1681(2017 Apr)
Zhang X,Du Y,Ling J,Li W,Liao Y,Wei X

Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.
Circulation research113(10)1138-47(2013 Oct)
Abonnenc M,Nabeebaccus AA,Mayr U,Barallobre-Barreiro J,Dong X,Cuello F,Sur S,Drozdov I,Langley SR,Lu R,Stathopoulou K,Didangelos A,Yin X,Zimmermann WH,Shah AM,Zampetaki A,Mayr M

Adenovirus-delivered DKK3/WNT4 and steroidogenesis in primary cultures of adrenocortical cells.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme38(9)549-55(2006 Sep)
Chen M,Hornsby PJ

Functional characterization of WNT7A signaling in PC12 cells: interaction with A FZD5 x LRP6 receptor complex and modulation by Dickkopf proteins.
The Journal of biological chemistry278(39)37024-31(2003 Sep)
Caricasole A,Ferraro T,Iacovelli L,Barletta E,Caruso A,Melchiorri D,Terstappen GC,Nicoletti F

Zonal expression of dickkopf-3 and components of the Wnt signalling pathways in the human adrenal cortex.
The Journal of endocrinology178(1)149-58(2003 Jul)
Suwa T,Chen M,Hawks CL,Hornsby PJ

REQUEST A QUOTE

EMAIL

[email protected]

PHONE

1-877-436-7274

ONLINE FORM

Online Quote Submission

ONLINE FORM

Online Quote Submission

Dkk3 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

REQUEST A QUOTE

EMAIL

PHONE

ONLINE FORM

ONLINE FORM

SUPPORT

COMPANY

SUPPORT

COMPANY