SLC7A8 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Gene Symbol	SLC7A8
Entrez Gene ID	23428
Full Name	solute carrier family 7 member 8
Synonyms	LAT2,LPI-PC1
General protein information	Preferred Names solute carrier family 7 member 8 Names large neutral amino acids transporter small subunit 2 L-type amino acid transporter 2 integral membrane protein E16H solute carrier family 7 (amino acid transporter light chain, L system), member 8 solute carrier family 7 (amino acid transporter, L-type), member 8 solute carrier family 7 (cationic amino acid transporter, y+ system), member 8
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 14 Map Location: 14q11.2
Disorder MIM:	604235

mRNA and Protein(s)

mRNA	Protein	Name
NM_182728.3	NP_877392.1	large neutral amino acids transporter small subunit 2 isoform b
NM_001267036.1	NP_001253965.1	large neutral amino acids transporter small subunit 2 isoform c
NM_182728.2	NP_877392.1	large neutral amino acids transporter small subunit 2 isoform b
NM_012244.4	NP_036376.2	large neutral amino acids transporter small subunit 2 isoform a
NM_012244.3	NP_036376.2	large neutral amino acids transporter small subunit 2 isoform a
NM_001267037.1	NP_001253966.1	large neutral amino acids transporter small subunit 2 isoform d

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	SLC7A8	XP_001161755.1
Danio rerio (zebrafish)	slc7a8a	NP_001258826.1
Homo sapiens (human)	SLC7A8	NP_036376.2
Canis lupus familiaris (dog)	SLC7A8	XP_547730.1
Rattus norvegicus (Norway rat)	Slc7a8	NP_445894.1
Drosophila melanogaster (fruit fly)	gb	NP_651536.1
	SLC7A8	XP_001106771.1
Bos taurus (cattle)	SLC7A8	NP_001179818.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP003425	XP_311711.3
Xenopus tropicalis (tropical clawed frog)	slc7a8	NP_988983.1
Mus musculus (house mouse)	Slc7a8	NP_058668.1

Gene Ontology
Bibliography

Related articles in PubMed

Mutations in L-type amino acid transporter-2 support
Espino Gaurch M, Font-Llitj?s M, Murillo-Cuesta S, Errasti-Murugarren E, Celaya AM, Girotto G, Vuckovic D, Mezzavilla M, Vilches C, Bodoy S, Sah?n I, Gonz?lez L, Prat E, Zorzano A, Dierssen M, Varela-Nieto I, Gasparini P, Palac?n M, Nunes V
eLife7(2018 Jan)

Overexpression of L-Type Amino Acid Transporter 1 (LAT1) and 2 (LAT2): Novel Markers of Neuroendocrine Tumors.
Barollo S, Bertazza L, Watutantrige-Fernando S, Censi S, Cavedon E, Galuppini F, Pennelli G, Fassina A, Citton M, Rubin B, Pezzani R, Benna C, Opocher G, Iacobone M, Mian C
PloS one11(5)e0156044(2016)

Expression and functional characterisation of System L amino acid transporters in the human term placenta.
Gaccioli F, Aye IL, Roos S, Lager S, Ramirez VI, Kanai Y, Powell TL, Jansson T
Reproductive biology and endocrinology : RB&E1357(2015 Jun)

Detergent-induced stabilization and improved 3D map of the human heteromeric amino acid transporter 4F2hc-LAT2.
Meury M, Costa M, Harder D, Stauffer M, Jeckelmann JM, Br?hlmann B, Rosell A, Ilg? H, Kovar K, Palac?n M, Fotiadis D
PloS one9(10)e109882(2014)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

LAT1 and LAT2 are present and functional in the syncytiotrophoblast MVM, whereas LAT2 is also expressed in the BM and in the fetal capillary endothelium.
Title: Expression and functional characterisation of System L amino acid transporters in the human term placenta.

Compared with the adult cerebral cortex, mRNAs encoding OATP1A2, OATP1C1, OATP3A1 variant 2, OATP4A1, LAT2 and CD98 were reduced in fetal cortex at different gestational ages, whilst mRNAs encoding MCT8, MCT10, OATP3A1 variant 1 and LAT1 were similar.
Title: The expression of thyroid hormone transporters in the human fetal cerebral cortex during early development and in N-Tera-2 neurodifferentiation.

Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
Title: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.

Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.

Observational study of gene-disease association. (HuGE Navigator)
Title: Association of genetic variants with hemorrhagic stroke in Japanese individuals.

The following SLC7A8 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SLC7A8 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu02296	NM_182728.3 Latest version!	Homo sapiens solute carrier family 7 member 8 (SLC7A8), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00
OHu06127	NM_012244.4 Latest version!	Homo sapiens solute carrier family 7 member 8 (SLC7A8), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$219.50-$307.30 $439.00
OHu11788	NM_001267036.1 Latest version!	Homo sapiens solute carrier family 7 member 8 (SLC7A8), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu56024	NM_001267037.1 Latest version!	Homo sapiens solute carrier family 7 member 8 (SLC7A8), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
View Old Accession Versions >>
OHu02296	NM_182728.2	Homo sapiens solute carrier family 7 member 8 (SLC7A8), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00
OHu06127	NM_012244.3	Homo sapiens solute carrier family 7 member 8 (SLC7A8), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$219.50-$307.30 $439.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

SLC7A8 ( NM_182728.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_877392.1 Homo sapiens solute carrier family 7 member 8 (SLC7A8), transcript variant 2, mRNA.

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CloneID	OHu02296
Clone ID Related Accession (Same CDS sequence)	NM_182728.3 , NM_182728.2
Accession Version	NM_182728.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 999bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-20
Organism	Homo sapiens(human)
Product	large neutral amino acids transporter small subunit 2 isoform b
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BX248288.1, AB037669.1 and AF135830.1. On Jun 1, 2019 this sequence version replaced NM_182728.2. Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region and initiates translation at a downstream, in-frame start codon, compared to variant 1. The encoded isoform (b) has a shorter N-terminus, compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR7346977.1505311.1, BX248288.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGGATTG TACAGATATG CAAAGGAGAG TACTTCTGGC TGGAGCCAAA GAATGCATTT 
GAGAATTTCC AGGAACCTGA CATCGGCCTC GTCGCACTGG CTTTCCTTCA GGGCTCCTTT 
GCCTATGGAG GCTGGAACTT TCTGAATTAC GTGACTGAGG AGCTTGTTGA TCCCTACAAG 
AACCTTCCCA GAGCCATCTT CATCTCCATC CCACTGGTCA CATTTGTGTA TGTCTTTGCC 
AATGTCGCTT ATGTCACTGC AATGTCCCCC CAGGAGCTGC TGGCATCCAA CGCCGTCGCT 
GTGACTTTTG GAGAGAAGCT CCTAGGAGTC ATGGCCTGGA TCATGCCCAT TTCTGTTGCC 
CTGTCCACAT TTGGAGGAGT TAATGGGTCT CTCTTCACCT CCTCTCGGCT GTTCTTCGCT 
GGAGCCCGAG AGGGCCACCT TCCCAGTGTG TTGGCCATGA TCCACGTGAA GCGCTGCACC 
CCAATCCCAG CCCTGCTCTT CACATGCATC TCCACCCTGC TGATGCTGGT CACCAGCGAC 
ATGTACACAC TCATCAACTA TGTGGGCTTC ATCAACTACC TCTTCTATGG GGTCACGGTT 
GCTGGACAGA TAGTCCTTCG CTGGAAGAAG CCTGATATCC CCCGCCCCAT CAAGATCAAC 
CTGCTGTTCC CCATCATCTA CTTGCTGTTC TGGGCCTTCC TGCTGGTCTT CAGCCTGTGG 
TCAGAGCCGG TGGTGTGTGG CATTGGCCTG GCCATCATGC TGACAGGAGT GCCTGTCTAT 
TTCCTGGGTG TTTACTGGCA ACACAAGCCC AAGTGTTTCA GTGACTTCAT TGAGCTGCTA 
ACCCTGGTGA GCCAGAAGAT GTGTGTGGTC GTGTACCCCG AGGTGGAGCG GGGCTCAGGG 
ACAGAGGAGG CTAATGAGGA CATGGAGGAG CAGCAGCAGC CCATGTACCA ACCCACTCCC 
ACGAAGGACA AGGACGTGGC GGGGCAGCCC CAGCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_877392.1
CDS	237..1235
Translation	MGIVQICKGEYFWLEPKNAFENFQEPDIGLVALAFLQGSFAYGGWNFLNYVTEELVDPYKNLPRAIFISIPLVTFVYVFANVAYVTAMSPQELLASNAVAVTFGEKLLGVMAWIMPISVALSTFGGVNGSLFTSSRLFFAGAREGHLPSVLAMIHVKRCTPIPALLFTCISTLLMLVTSDMYTLINYVGFINYLFYGVTVAGQIVLRWKKPDIPRPIKINLLFPIIYLLFWAFLLVFSLWSEPVVCGIGLAIMLTGVPVYFLGVYWQHKPKCFSDFIELLTLVSQKMCVVVYPEVERGSGTEEANEDMEEQQQPMYQPTPTKDKDVAGQPQP

Target ORF information:

RefSeq Version	NM_182728.3
Organism	Homo sapiens(human)
Definition	Homo sapiens solute carrier family 7 member 8 (SLC7A8), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_182728.3

ORF Insert Sequence:

ATGGGGATTG TACAGATATG CAAAGGAGAG TACTTCTGGC TGGAGCCAAA GAATGCATTT 
GAGAATTTCC AGGAACCTGA CATCGGCCTC GTCGCACTGG CTTTCCTTCA GGGCTCCTTT 
GCCTATGGAG GCTGGAACTT TCTGAATTAC GTGACTGAGG AGCTTGTTGA TCCCTACAAG 
AACCTTCCCA GAGCCATCTT CATCTCCATC CCACTGGTCA CATTTGTGTA TGTCTTTGCC 
AATGTCGCTT ATGTCACTGC AATGTCCCCC CAGGAGCTGC TGGCATCCAA CGCCGTCGCT 
GTGACTTTTG GAGAGAAGCT CCTAGGAGTC ATGGCCTGGA TCATGCCCAT TTCTGTTGCC 
CTGTCCACAT TTGGAGGAGT TAATGGGTCT CTCTTCACCT CCTCTCGGCT GTTCTTCGCT 
GGAGCCCGAG AGGGCCACCT TCCCAGTGTG TTGGCCATGA TCCACGTGAA GCGCTGCACC 
CCAATCCCAG CCCTGCTCTT CACATGCATC TCCACCCTGC TGATGCTGGT CACCAGCGAC 
ATGTACACAC TCATCAACTA TGTGGGCTTC ATCAACTACC TCTTCTATGG GGTCACGGTT 
GCTGGACAGA TAGTCCTTCG CTGGAAGAAG CCTGATATCC CCCGCCCCAT CAAGATCAAC 
CTGCTGTTCC CCATCATCTA CTTGCTGTTC TGGGCCTTCC TGCTGGTCTT CAGCCTGTGG 
TCAGAGCCGG TGGTGTGTGG CATTGGCCTG GCCATCATGC TGACAGGAGT GCCTGTCTAT 
TTCCTGGGTG TTTACTGGCA ACACAAGCCC AAGTGTTTCA GTGACTTCAT TGAGCTGCTA 
ACCCTGGTGA GCCAGAAGAT GTGTGTGGTC GTGTACCCCG AGGTGGAGCG GGGCTCAGGG 
ACAGAGGAGG CTAATGAGGA CATGGAGGAG CAGCAGCAGC CCATGTACCA ACCCACTCCC 
ACGAAGGACA AGGACGTGGC GGGGCAGCCC CAGCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SLC7A8 ( NM_182728.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_877392.1 Homo sapiens solute carrier family 7 member 8 (SLC7A8), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu02296
Clone ID Related Accession (Same CDS sequence)	NM_182728.3 , NM_182728.2
Accession Version	NM_182728.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 999bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-22
Organism	Homo sapiens(human)
Product	large neutral amino acids transporter small subunit 2 isoform b
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DC348596.1, BX248288.1, AB037669.1 and AF135830.1. On May 24, 2012 this sequence version replaced NM_182728.1. Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region and initiates translation at a downstream, in-frame start codon, compared to variant 1. The encoded isoform (b) has a shorter N-terminus, compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BX248288.1, SRR1660809.126209.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGGATTG TACAGATATG CAAAGGAGAG TACTTCTGGC TGGAGCCAAA GAATGCATTT 
GAGAATTTCC AGGAACCTGA CATCGGCCTC GTCGCACTGG CTTTCCTTCA GGGCTCCTTT 
GCCTATGGAG GCTGGAACTT TCTGAATTAC GTGACTGAGG AGCTTGTTGA TCCCTACAAG 
AACCTTCCCA GAGCCATCTT CATCTCCATC CCACTGGTCA CATTTGTGTA TGTCTTTGCC 
AATGTCGCTT ATGTCACTGC AATGTCCCCC CAGGAGCTGC TGGCATCCAA CGCCGTCGCT 
GTGACTTTTG GAGAGAAGCT CCTAGGAGTC ATGGCCTGGA TCATGCCCAT TTCTGTTGCC 
CTGTCCACAT TTGGAGGAGT TAATGGGTCT CTCTTCACCT CCTCTCGGCT GTTCTTCGCT 
GGAGCCCGAG AGGGCCACCT TCCCAGTGTG TTGGCCATGA TCCACGTGAA GCGCTGCACC 
CCAATCCCAG CCCTGCTCTT CACATGCATC TCCACCCTGC TGATGCTGGT CACCAGCGAC 
ATGTACACAC TCATCAACTA TGTGGGCTTC ATCAACTACC TCTTCTATGG GGTCACGGTT 
GCTGGACAGA TAGTCCTTCG CTGGAAGAAG CCTGATATCC CCCGCCCCAT CAAGATCAAC 
CTGCTGTTCC CCATCATCTA CTTGCTGTTC TGGGCCTTCC TGCTGGTCTT CAGCCTGTGG 
TCAGAGCCGG TGGTGTGTGG CATTGGCCTG GCCATCATGC TGACAGGAGT GCCTGTCTAT 
TTCCTGGGTG TTTACTGGCA ACACAAGCCC AAGTGTTTCA GTGACTTCAT TGAGCTGCTA 
ACCCTGGTGA GCCAGAAGAT GTGTGTGGTC GTGTACCCCG AGGTGGAGCG GGGCTCAGGG 
ACAGAGGAGG CTAATGAGGA CATGGAGGAG CAGCAGCAGC CCATGTACCA ACCCACTCCC 
ACGAAGGACA AGGACGTGGC GGGGCAGCCC CAGCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_877392.1
CDS	294..1292
Translation	MGIVQICKGEYFWLEPKNAFENFQEPDIGLVALAFLQGSFAYGGWNFLNYVTEELVDPYKNLPRAIFISIPLVTFVYVFANVAYVTAMSPQELLASNAVAVTFGEKLLGVMAWIMPISVALSTFGGVNGSLFTSSRLFFAGAREGHLPSVLAMIHVKRCTPIPALLFTCISTLLMLVTSDMYTLINYVGFINYLFYGVTVAGQIVLRWKKPDIPRPIKINLLFPIIYLLFWAFLLVFSLWSEPVVCGIGLAIMLTGVPVYFLGVYWQHKPKCFSDFIELLTLVSQKMCVVVYPEVERGSGTEEANEDMEEQQQPMYQPTPTKDKDVAGQPQP

Target ORF information:

RefSeq Version	NM_182728.2
Organism	Homo sapiens(human)
Definition	Homo sapiens solute carrier family 7 member 8 (SLC7A8), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_182728.2

ORF Insert Sequence:

ATGGGGATTG TACAGATATG CAAAGGAGAG TACTTCTGGC TGGAGCCAAA GAATGCATTT 
GAGAATTTCC AGGAACCTGA CATCGGCCTC GTCGCACTGG CTTTCCTTCA GGGCTCCTTT 
GCCTATGGAG GCTGGAACTT TCTGAATTAC GTGACTGAGG AGCTTGTTGA TCCCTACAAG 
AACCTTCCCA GAGCCATCTT CATCTCCATC CCACTGGTCA CATTTGTGTA TGTCTTTGCC 
AATGTCGCTT ATGTCACTGC AATGTCCCCC CAGGAGCTGC TGGCATCCAA CGCCGTCGCT 
GTGACTTTTG GAGAGAAGCT CCTAGGAGTC ATGGCCTGGA TCATGCCCAT TTCTGTTGCC 
CTGTCCACAT TTGGAGGAGT TAATGGGTCT CTCTTCACCT CCTCTCGGCT GTTCTTCGCT 
GGAGCCCGAG AGGGCCACCT TCCCAGTGTG TTGGCCATGA TCCACGTGAA GCGCTGCACC 
CCAATCCCAG CCCTGCTCTT CACATGCATC TCCACCCTGC TGATGCTGGT CACCAGCGAC 
ATGTACACAC TCATCAACTA TGTGGGCTTC ATCAACTACC TCTTCTATGG GGTCACGGTT 
GCTGGACAGA TAGTCCTTCG CTGGAAGAAG CCTGATATCC CCCGCCCCAT CAAGATCAAC 
CTGCTGTTCC CCATCATCTA CTTGCTGTTC TGGGCCTTCC TGCTGGTCTT CAGCCTGTGG 
TCAGAGCCGG TGGTGTGTGG CATTGGCCTG GCCATCATGC TGACAGGAGT GCCTGTCTAT 
TTCCTGGGTG TTTACTGGCA ACACAAGCCC AAGTGTTTCA GTGACTTCAT TGAGCTGCTA 
ACCCTGGTGA GCCAGAAGAT GTGTGTGGTC GTGTACCCCG AGGTGGAGCG GGGCTCAGGG 
ACAGAGGAGG CTAATGAGGA CATGGAGGAG CAGCAGCAGC CCATGTACCA ACCCACTCCC 
ACGAAGGACA AGGACGTGGC GGGGCAGCCC CAGCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SLC7A8 ( NM_012244.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_036376.2 Homo sapiens solute carrier family 7 member 8 (SLC7A8), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu06127
Clone ID Related Accession (Same CDS sequence)	NM_012244.4 , NM_012244.3
Accession Version	NM_012244.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1608bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-29
Organism	Homo sapiens(human)
Product	large neutral amino acids transporter small subunit 2 isoform a
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK223610.1, AL365343.2, AK313465.1, BX248288.1, AB037669.1 and AF135830.1. On Nov 23, 2018 this sequence version replaced NM_012244.3. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: Y18483.1, AB037669.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000316902.12/ ENSP00000320378.7 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGAAGAAG GAGCCAGGCA CCGAAACAAC ACCGAAAAGA AACACCCAGG TGGGGGCGAG 
TCGGACGCCA GCCCCGAGGC TGGTTCCGGA GGGGGCGGAG TAGCCCTGAA GAAAGAGATC 
GGATTGGTCA GTGCCTGTGG TATCATCGTA GGGAACATCA TCGGCTCTGG AATCTTTGTC 
TCGCCAAAGG GAGTGCTGGA GAATGCTGGT TCTGTGGGCC TTGCTCTCAT CGTCTGGATT 
GTGACGGGCT TCATCACAGT TGTGGGAGCC CTCTGCTATG CTGAACTCGG GGTCACCATC 
CCCAAATCTG GAGGTGACTA CTCCTATGTC AAGGACATCT TCGGAGGACT GGCTGGGTTC 
CTGAGGCTGT GGATTGCTGT GCTGGTGATC TACCCCACCA ACCAGGCTGT CATCGCCCTC 
ACCTTCTCCA ACTACGTGCT GCAGCCGCTC TTCCCCACCT GCTTCCCCCC AGAGTCTGGC 
CTTCGGCTCC TGGCTGCCAT CTGCTTATTG CTCCTCACAT GGGTCAACTG TTCCAGTGTG 
CGGTGGGCCA CCCGGGTTCA AGACATCTTC ACAGCTGGGA AGCTCCTGGC CTTGGCCCTG 
ATTATCATCA TGGGGATTGT ACAGATATGC AAAGGAGAGT ACTTCTGGCT GGAGCCAAAG 
AATGCATTTG AGAATTTCCA GGAACCTGAC ATCGGCCTCG TCGCACTGGC TTTCCTTCAG 
GGCTCCTTTG CCTATGGAGG CTGGAACTTT CTGAATTACG TGACTGAGGA GCTTGTTGAT 
CCCTACAAGA ACCTTCCCAG AGCCATCTTC ATCTCCATCC CACTGGTCAC ATTTGTGTAT 
GTCTTTGCCA ATGTCGCTTA TGTCACTGCA ATGTCCCCCC AGGAGCTGCT GGCATCCAAC 
GCCGTCGCTG TGACTTTTGG AGAGAAGCTC CTAGGAGTCA TGGCCTGGAT CATGCCCATT 
TCTGTTGCCC TGTCCACATT TGGAGGAGTT AATGGGTCTC TCTTCACCTC CTCTCGGCTG 
TTCTTCGCTG GAGCCCGAGA GGGCCACCTT CCCAGTGTGT TGGCCATGAT CCACGTGAAG 
CGCTGCACCC CAATCCCAGC CCTGCTCTTC ACATGCATCT CCACCCTGCT GATGCTGGTC 
ACCAGCGACA TGTACACACT CATCAACTAT GTGGGCTTCA TCAACTACCT CTTCTATGGG 
GTCACGGTTG CTGGACAGAT AGTCCTTCGC TGGAAGAAGC CTGATATCCC CCGCCCCATC 
AAGATCAACC TGCTGTTCCC CATCATCTAC TTGCTGTTCT GGGCCTTCCT GCTGGTCTTC 
AGCCTGTGGT CAGAGCCGGT GGTGTGTGGC ATTGGCCTGG CCATCATGCT GACAGGAGTG 
CCTGTCTATT TCCTGGGTGT TTACTGGCAA CACAAGCCCA AGTGTTTCAG TGACTTCATT 
GAGCTGCTAA CCCTGGTGAG CCAGAAGATG TGTGTGGTCG TGTACCCCGA GGTGGAGCGG 
GGCTCAGGGA CAGAGGAGGC TAATGAGGAC ATGGAGGAGC AGCAGCAGCC CATGTACCAA 
CCCACTCCCA CGAAGGACAA GGACGTGGCG GGGCAGCCCC AGCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_036376.2
CDS	747..2354
Translation	MEEGARHRNNTEKKHPGGGESDASPEAGSGGGGVALKKEIGLVSACGIIVGNIIGSGIFVSPKGVLENAGSVGLALIVWIVTGFITVVGALCYAELGVTIPKSGGDYSYVKDIFGGLAGFLRLWIAVLVIYPTNQAVIALTFSNYVLQPLFPTCFPPESGLRLLAAICLLLLTWVNCSSVRWATRVQDIFTAGKLLALALIIIMGIVQICKGEYFWLEPKNAFENFQEPDIGLVALAFLQGSFAYGGWNFLNYVTEELVDPYKNLPRAIFISIPLVTFVYVFANVAYVTAMSPQELLASNAVAVTFGEKLLGVMAWIMPISVALSTFGGVNGSLFTSSRLFFAGAREGHLPSVLAMIHVKRCTPIPALLFTCISTLLMLVTSDMYTLINYVGFINYLFYGVTVAGQIVLRWKKPDIPRPIKINLLFPIIYLLFWAFLLVFSLWSEPVVCGIGLAIMLTGVPVYFLGVYWQHKPKCFSDFIELLTLVSQKMCVVVYPEVERGSGTEEANEDMEEQQQPMYQPTPTKDKDVAGQPQP

Target ORF information:

RefSeq Version	NM_012244.4
Organism	Homo sapiens(human)
Definition	Homo sapiens solute carrier family 7 member 8 (SLC7A8), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_012244.4

ORF Insert Sequence:

ATGGAAGAAG GAGCCAGGCA CCGAAACAAC ACCGAAAAGA AACACCCAGG TGGGGGCGAG 
TCGGACGCCA GCCCCGAGGC TGGTTCCGGA GGGGGCGGAG TAGCCCTGAA GAAAGAGATC 
GGATTGGTCA GTGCCTGTGG TATCATCGTA GGGAACATCA TCGGCTCTGG AATCTTTGTC 
TCGCCAAAGG GAGTGCTGGA GAATGCTGGT TCTGTGGGCC TTGCTCTCAT CGTCTGGATT 
GTGACGGGCT TCATCACAGT TGTGGGAGCC CTCTGCTATG CTGAACTCGG GGTCACCATC 
CCCAAATCTG GAGGTGACTA CTCCTATGTC AAGGACATCT TCGGAGGACT GGCTGGGTTC 
CTGAGGCTGT GGATTGCTGT GCTGGTGATC TACCCCACCA ACCAGGCTGT CATCGCCCTC 
ACCTTCTCCA ACTACGTGCT GCAGCCGCTC TTCCCCACCT GCTTCCCCCC AGAGTCTGGC 
CTTCGGCTCC TGGCTGCCAT CTGCTTATTG CTCCTCACAT GGGTCAACTG TTCCAGTGTG 
CGGTGGGCCA CCCGGGTTCA AGACATCTTC ACAGCTGGGA AGCTCCTGGC CTTGGCCCTG 
ATTATCATCA TGGGGATTGT ACAGATATGC AAAGGAGAGT ACTTCTGGCT GGAGCCAAAG 
AATGCATTTG AGAATTTCCA GGAACCTGAC ATCGGCCTCG TCGCACTGGC TTTCCTTCAG 
GGCTCCTTTG CCTATGGAGG CTGGAACTTT CTGAATTACG TGACTGAGGA GCTTGTTGAT 
CCCTACAAGA ACCTTCCCAG AGCCATCTTC ATCTCCATCC CACTGGTCAC ATTTGTGTAT 
GTCTTTGCCA ATGTCGCTTA TGTCACTGCA ATGTCCCCCC AGGAGCTGCT GGCATCCAAC 
GCCGTCGCTG TGACTTTTGG AGAGAAGCTC CTAGGAGTCA TGGCCTGGAT CATGCCCATT 
TCTGTTGCCC TGTCCACATT TGGAGGAGTT AATGGGTCTC TCTTCACCTC CTCTCGGCTG 
TTCTTCGCTG GAGCCCGAGA GGGCCACCTT CCCAGTGTGT TGGCCATGAT CCACGTGAAG 
CGCTGCACCC CAATCCCAGC CCTGCTCTTC ACATGCATCT CCACCCTGCT GATGCTGGTC 
ACCAGCGACA TGTACACACT CATCAACTAT GTGGGCTTCA TCAACTACCT CTTCTATGGG 
GTCACGGTTG CTGGACAGAT AGTCCTTCGC TGGAAGAAGC CTGATATCCC CCGCCCCATC 
AAGATCAACC TGCTGTTCCC CATCATCTAC TTGCTGTTCT GGGCCTTCCT GCTGGTCTTC 
AGCCTGTGGT CAGAGCCGGT GGTGTGTGGC ATTGGCCTGG CCATCATGCT GACAGGAGTG 
CCTGTCTATT TCCTGGGTGT TTACTGGCAA CACAAGCCCA AGTGTTTCAG TGACTTCATT 
GAGCTGCTAA CCCTGGTGAG CCAGAAGATG TGTGTGGTCG TGTACCCCGA GGTGGAGCGG 
GGCTCAGGGA CAGAGGAGGC TAATGAGGAC ATGGAGGAGC AGCAGCAGCC CATGTACCAA 
CCCACTCCCA CGAAGGACAA GGACGTGGCG GGGCAGCCCC AGCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SLC7A8 ( NM_012244.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_036376.2 Homo sapiens solute carrier family 7 member 8 (SLC7A8), transcript variant 1, mRNA.

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CloneID	OHu06127
Clone ID Related Accession (Same CDS sequence)	NM_012244.4 , NM_012244.3
Accession Version	NM_012244.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1608bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-27
Organism	Homo sapiens(human)
Product	large neutral amino acids transporter small subunit 2 isoform a
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK223610.1, AL365343.2, AK313465.1, BX248288.1, AB037669.1 and AF135830.1. On May 24, 2012 this sequence version replaced NM_012244.2. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: Y18483.1, AB037669.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAAGAAG GAGCCAGGCA CCGAAACAAC ACCGAAAAGA AACACCCAGG TGGGGGCGAG 
TCGGACGCCA GCCCCGAGGC TGGTTCCGGA GGGGGCGGAG TAGCCCTGAA GAAAGAGATC 
GGATTGGTCA GTGCCTGTGG TATCATCGTA GGGAACATCA TCGGCTCTGG AATCTTTGTC 
TCGCCAAAGG GAGTGCTGGA GAATGCTGGT TCTGTGGGCC TTGCTCTCAT CGTCTGGATT 
GTGACGGGCT TCATCACAGT TGTGGGAGCC CTCTGCTATG CTGAACTCGG GGTCACCATC 
CCCAAATCTG GAGGTGACTA CTCCTATGTC AAGGACATCT TCGGAGGACT GGCTGGGTTC 
CTGAGGCTGT GGATTGCTGT GCTGGTGATC TACCCCACCA ACCAGGCTGT CATCGCCCTC 
ACCTTCTCCA ACTACGTGCT GCAGCCGCTC TTCCCCACCT GCTTCCCCCC AGAGTCTGGC 
CTTCGGCTCC TGGCTGCCAT CTGCTTATTG CTCCTCACAT GGGTCAACTG TTCCAGTGTG 
CGGTGGGCCA CCCGGGTTCA AGACATCTTC ACAGCTGGGA AGCTCCTGGC CTTGGCCCTG 
ATTATCATCA TGGGGATTGT ACAGATATGC AAAGGAGAGT ACTTCTGGCT GGAGCCAAAG 
AATGCATTTG AGAATTTCCA GGAACCTGAC ATCGGCCTCG TCGCACTGGC TTTCCTTCAG 
GGCTCCTTTG CCTATGGAGG CTGGAACTTT CTGAATTACG TGACTGAGGA GCTTGTTGAT 
CCCTACAAGA ACCTTCCCAG AGCCATCTTC ATCTCCATCC CACTGGTCAC ATTTGTGTAT 
GTCTTTGCCA ATGTCGCTTA TGTCACTGCA ATGTCCCCCC AGGAGCTGCT GGCATCCAAC 
GCCGTCGCTG TGACTTTTGG AGAGAAGCTC CTAGGAGTCA TGGCCTGGAT CATGCCCATT 
TCTGTTGCCC TGTCCACATT TGGAGGAGTT AATGGGTCTC TCTTCACCTC CTCTCGGCTG 
TTCTTCGCTG GAGCCCGAGA GGGCCACCTT CCCAGTGTGT TGGCCATGAT CCACGTGAAG 
CGCTGCACCC CAATCCCAGC CCTGCTCTTC ACATGCATCT CCACCCTGCT GATGCTGGTC 
ACCAGCGACA TGTACACACT CATCAACTAT GTGGGCTTCA TCAACTACCT CTTCTATGGG 
GTCACGGTTG CTGGACAGAT AGTCCTTCGC TGGAAGAAGC CTGATATCCC CCGCCCCATC 
AAGATCAACC TGCTGTTCCC CATCATCTAC TTGCTGTTCT GGGCCTTCCT GCTGGTCTTC 
AGCCTGTGGT CAGAGCCGGT GGTGTGTGGC ATTGGCCTGG CCATCATGCT GACAGGAGTG 
CCTGTCTATT TCCTGGGTGT TTACTGGCAA CACAAGCCCA AGTGTTTCAG TGACTTCATT 
GAGCTGCTAA CCCTGGTGAG CCAGAAGATG TGTGTGGTCG TGTACCCCGA GGTGGAGCGG 
GGCTCAGGGA CAGAGGAGGC TAATGAGGAC ATGGAGGAGC AGCAGCAGCC CATGTACCAA 
CCCACTCCCA CGAAGGACAA GGACGTGGCG GGGCAGCCCC AGCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_036376.2
CDS	747..2354
Translation	MEEGARHRNNTEKKHPGGGESDASPEAGSGGGGVALKKEIGLVSACGIIVGNIIGSGIFVSPKGVLENAGSVGLALIVWIVTGFITVVGALCYAELGVTIPKSGGDYSYVKDIFGGLAGFLRLWIAVLVIYPTNQAVIALTFSNYVLQPLFPTCFPPESGLRLLAAICLLLLTWVNCSSVRWATRVQDIFTAGKLLALALIIIMGIVQICKGEYFWLEPKNAFENFQEPDIGLVALAFLQGSFAYGGWNFLNYVTEELVDPYKNLPRAIFISIPLVTFVYVFANVAYVTAMSPQELLASNAVAVTFGEKLLGVMAWIMPISVALSTFGGVNGSLFTSSRLFFAGAREGHLPSVLAMIHVKRCTPIPALLFTCISTLLMLVTSDMYTLINYVGFINYLFYGVTVAGQIVLRWKKPDIPRPIKINLLFPIIYLLFWAFLLVFSLWSEPVVCGIGLAIMLTGVPVYFLGVYWQHKPKCFSDFIELLTLVSQKMCVVVYPEVERGSGTEEANEDMEEQQQPMYQPTPTKDKDVAGQPQP

Target ORF information:

RefSeq Version	NM_012244.3
Organism	Homo sapiens(human)
Definition	Homo sapiens solute carrier family 7 member 8 (SLC7A8), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_012244.3

ORF Insert Sequence:

ATGGAAGAAG GAGCCAGGCA CCGAAACAAC ACCGAAAAGA AACACCCAGG TGGGGGCGAG 
TCGGACGCCA GCCCCGAGGC TGGTTCCGGA GGGGGCGGAG TAGCCCTGAA GAAAGAGATC 
GGATTGGTCA GTGCCTGTGG TATCATCGTA GGGAACATCA TCGGCTCTGG AATCTTTGTC 
TCGCCAAAGG GAGTGCTGGA GAATGCTGGT TCTGTGGGCC TTGCTCTCAT CGTCTGGATT 
GTGACGGGCT TCATCACAGT TGTGGGAGCC CTCTGCTATG CTGAACTCGG GGTCACCATC 
CCCAAATCTG GAGGTGACTA CTCCTATGTC AAGGACATCT TCGGAGGACT GGCTGGGTTC 
CTGAGGCTGT GGATTGCTGT GCTGGTGATC TACCCCACCA ACCAGGCTGT CATCGCCCTC 
ACCTTCTCCA ACTACGTGCT GCAGCCGCTC TTCCCCACCT GCTTCCCCCC AGAGTCTGGC 
CTTCGGCTCC TGGCTGCCAT CTGCTTATTG CTCCTCACAT GGGTCAACTG TTCCAGTGTG 
CGGTGGGCCA CCCGGGTTCA AGACATCTTC ACAGCTGGGA AGCTCCTGGC CTTGGCCCTG 
ATTATCATCA TGGGGATTGT ACAGATATGC AAAGGAGAGT ACTTCTGGCT GGAGCCAAAG 
AATGCATTTG AGAATTTCCA GGAACCTGAC ATCGGCCTCG TCGCACTGGC TTTCCTTCAG 
GGCTCCTTTG CCTATGGAGG CTGGAACTTT CTGAATTACG TGACTGAGGA GCTTGTTGAT 
CCCTACAAGA ACCTTCCCAG AGCCATCTTC ATCTCCATCC CACTGGTCAC ATTTGTGTAT 
GTCTTTGCCA ATGTCGCTTA TGTCACTGCA ATGTCCCCCC AGGAGCTGCT GGCATCCAAC 
GCCGTCGCTG TGACTTTTGG AGAGAAGCTC CTAGGAGTCA TGGCCTGGAT CATGCCCATT 
TCTGTTGCCC TGTCCACATT TGGAGGAGTT AATGGGTCTC TCTTCACCTC CTCTCGGCTG 
TTCTTCGCTG GAGCCCGAGA GGGCCACCTT CCCAGTGTGT TGGCCATGAT CCACGTGAAG 
CGCTGCACCC CAATCCCAGC CCTGCTCTTC ACATGCATCT CCACCCTGCT GATGCTGGTC 
ACCAGCGACA TGTACACACT CATCAACTAT GTGGGCTTCA TCAACTACCT CTTCTATGGG 
GTCACGGTTG CTGGACAGAT AGTCCTTCGC TGGAAGAAGC CTGATATCCC CCGCCCCATC 
AAGATCAACC TGCTGTTCCC CATCATCTAC TTGCTGTTCT GGGCCTTCCT GCTGGTCTTC 
AGCCTGTGGT CAGAGCCGGT GGTGTGTGGC ATTGGCCTGG CCATCATGCT GACAGGAGTG 
CCTGTCTATT TCCTGGGTGT TTACTGGCAA CACAAGCCCA AGTGTTTCAG TGACTTCATT 
GAGCTGCTAA CCCTGGTGAG CCAGAAGATG TGTGTGGTCG TGTACCCCGA GGTGGAGCGG 
GGCTCAGGGA CAGAGGAGGC TAATGAGGAC ATGGAGGAGC AGCAGCAGCC CATGTACCAA 
CCCACTCCCA CGAAGGACAA GGACGTGGCG GGGCAGCCCC AGCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SLC7A8 ( NM_001267036.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001253965.1 Homo sapiens solute carrier family 7 member 8 (SLC7A8), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu11788
Clone ID Related Accession (Same CDS sequence)	NM_001267036.1
Accession Version	NM_001267036.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1293bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-20
Organism	Homo sapiens(human)
Product	large neutral amino acids transporter small subunit 2 isoform c
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL117258.4, AK296702.1, BX248288.1, AB037669.1 and AF135830.1. Transcript Variant: This variant (3) differs in the 5' UTR, lacks a portion of the 5' coding region and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (c) is shorter and has a distinct N-terminus, compared to isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK296702.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGGCAGT ATGGGCAGGA GCTTAGCTGG AAGTGTTTGG TAAAAGCTGT GTGCCTCCAG 
GAGCACTCAC AGCCCTCACA GCTTCTCTGC ACCCTCCTCC TCTGCTGGTG TGTCCTTGGA 
AGAGAGAGGC CCTTCCGGAA GGCTCAGAGC ACCTCCTCTC CTTTGGAGGG GGTTCCGAGA 
TTTCTAAAAC GTTTGCTCCT CACATGGGTC AACTGTTCCA GTGTGCGGTG GGCCACCCGG 
GTTCAAGACA TCTTCACAGC TGGGAAGCTC CTGGCCTTGG CCCTGATTAT CATCATGGGG 
ATTGTACAGA TATGCAAAGG AGAGTACTTC TGGCTGGAGC CAAAGAATGC ATTTGAGAAT 
TTCCAGGAAC CTGACATCGG CCTCGTCGCA CTGGCTTTCC TTCAGGGCTC CTTTGCCTAT 
GGAGGCTGGA ACTTTCTGAA TTACGTGACT GAGGAGCTTG TTGATCCCTA CAAGAACCTT 
CCCAGAGCCA TCTTCATCTC CATCCCACTG GTCACATTTG TGTATGTCTT TGCCAATGTC 
GCTTATGTCA CTGCAATGTC CCCCCAGGAG CTGCTGGCAT CCAACGCCGT CGCTGTGACT 
TTTGGAGAGA AGCTCCTAGG AGTCATGGCC TGGATCATGC CCATTTCTGT TGCCCTGTCC 
ACATTTGGAG GAGTTAATGG GTCTCTCTTC ACCTCCTCTC GGCTGTTCTT CGCTGGAGCC 
CGAGAGGGCC ACCTTCCCAG TGTGTTGGCC ATGATCCACG TGAAGCGCTG CACCCCAATC 
CCAGCCCTGC TCTTCACATG CATCTCCACC CTGCTGATGC TGGTCACCAG CGACATGTAC 
ACACTCATCA ACTATGTGGG CTTCATCAAC TACCTCTTCT ATGGGGTCAC GGTTGCTGGA 
CAGATAGTCC TTCGCTGGAA GAAGCCTGAT ATCCCCCGCC CCATCAAGAT CAACCTGCTG 
TTCCCCATCA TCTACTTGCT GTTCTGGGCC TTCCTGCTGG TCTTCAGCCT GTGGTCAGAG 
CCGGTGGTGT GTGGCATTGG CCTGGCCATC ATGCTGACAG GAGTGCCTGT CTATTTCCTG 
GGTGTTTACT GGCAACACAA GCCCAAGTGT TTCAGTGACT TCATTGAGCT GCTAACCCTG 
GTGAGCCAGA AGATGTGTGT GGTCGTGTAC CCCGAGGTGG AGCGGGGCTC AGGGACAGAG 
GAGGCTAATG AGGACATGGA GGAGCAGCAG CAGCCCATGT ACCAACCCAC TCCCACGAAG 
GACAAGGACG TGGCGGGGCA GCCCCAGCCC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001253965.1
CDS	101..1393
Translation	MGQYGQELSWKCLVKAVCLQEHSQPSQLLCTLLLCWCVLGRERPFRKAQSTSSPLEGVPRFLKRLLLTWVNCSSVRWATRVQDIFTAGKLLALALIIIMGIVQICKGEYFWLEPKNAFENFQEPDIGLVALAFLQGSFAYGGWNFLNYVTEELVDPYKNLPRAIFISIPLVTFVYVFANVAYVTAMSPQELLASNAVAVTFGEKLLGVMAWIMPISVALSTFGGVNGSLFTSSRLFFAGAREGHLPSVLAMIHVKRCTPIPALLFTCISTLLMLVTSDMYTLINYVGFINYLFYGVTVAGQIVLRWKKPDIPRPIKINLLFPIIYLLFWAFLLVFSLWSEPVVCGIGLAIMLTGVPVYFLGVYWQHKPKCFSDFIELLTLVSQKMCVVVYPEVERGSGTEEANEDMEEQQQPMYQPTPTKDKDVAGQPQP

Target ORF information:

RefSeq Version	NM_001267036.1
Organism	Homo sapiens(human)
Definition	Homo sapiens solute carrier family 7 member 8 (SLC7A8), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001267036.1

ORF Insert Sequence:

ATGGGGCAGT ATGGGCAGGA GCTTAGCTGG AAGTGTTTGG TAAAAGCTGT GTGCCTCCAG 
GAGCACTCAC AGCCCTCACA GCTTCTCTGC ACCCTCCTCC TCTGCTGGTG TGTCCTTGGA 
AGAGAGAGGC CCTTCCGGAA GGCTCAGAGC ACCTCCTCTC CTTTGGAGGG GGTTCCGAGA 
TTTCTAAAAC GTTTGCTCCT CACATGGGTC AACTGTTCCA GTGTGCGGTG GGCCACCCGG 
GTTCAAGACA TCTTCACAGC TGGGAAGCTC CTGGCCTTGG CCCTGATTAT CATCATGGGG 
ATTGTACAGA TATGCAAAGG AGAGTACTTC TGGCTGGAGC CAAAGAATGC ATTTGAGAAT 
TTCCAGGAAC CTGACATCGG CCTCGTCGCA CTGGCTTTCC TTCAGGGCTC CTTTGCCTAT 
GGAGGCTGGA ACTTTCTGAA TTACGTGACT GAGGAGCTTG TTGATCCCTA CAAGAACCTT 
CCCAGAGCCA TCTTCATCTC CATCCCACTG GTCACATTTG TGTATGTCTT TGCCAATGTC 
GCTTATGTCA CTGCAATGTC CCCCCAGGAG CTGCTGGCAT CCAACGCCGT CGCTGTGACT 
TTTGGAGAGA AGCTCCTAGG AGTCATGGCC TGGATCATGC CCATTTCTGT TGCCCTGTCC 
ACATTTGGAG GAGTTAATGG GTCTCTCTTC ACCTCCTCTC GGCTGTTCTT CGCTGGAGCC 
CGAGAGGGCC ACCTTCCCAG TGTGTTGGCC ATGATCCACG TGAAGCGCTG CACCCCAATC 
CCAGCCCTGC TCTTCACATG CATCTCCACC CTGCTGATGC TGGTCACCAG CGACATGTAC 
ACACTCATCA ACTATGTGGG CTTCATCAAC TACCTCTTCT ATGGGGTCAC GGTTGCTGGA 
CAGATAGTCC TTCGCTGGAA GAAGCCTGAT ATCCCCCGCC CCATCAAGAT CAACCTGCTG 
TTCCCCATCA TCTACTTGCT GTTCTGGGCC TTCCTGCTGG TCTTCAGCCT GTGGTCAGAG 
CCGGTGGTGT GTGGCATTGG CCTGGCCATC ATGCTGACAG GAGTGCCTGT CTATTTCCTG 
GGTGTTTACT GGCAACACAA GCCCAAGTGT TTCAGTGACT TCATTGAGCT GCTAACCCTG 
GTGAGCCAGA AGATGTGTGT GGTCGTGTAC CCCGAGGTGG AGCGGGGCTC AGGGACAGAG 
GAGGCTAATG AGGACATGGA GGAGCAGCAG CAGCCCATGT ACCAACCCAC TCCCACGAAG 
GACAAGGACG TGGCGGGGCA GCCCCAGCCC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SLC7A8 ( NM_001267037.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001253966.1 Homo sapiens solute carrier family 7 member 8 (SLC7A8), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OHu56024
Clone ID Related Accession (Same CDS sequence)	NM_001267037.1
Accession Version	NM_001267037.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 936bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-20
Organism	Homo sapiens(human)
Product	large neutral amino acids transporter small subunit 2 isoform d
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DC348596.1, AK300384.1, BX248288.1, AB037669.1 and AF135830.1. Transcript Variant: This variant (4) differs in the 5' UTR, lacks a portion of the 5' coding region, initiates translation at an alternate start codon and lacks an exon in the coding region, compared to variant 1. The encoded isoform (d) is shorter and has a distinct N-terminus, compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK300384.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGTCAAC TGTTCCAGTG TGCGGTGGGC CACCCGGGTT CAAGACATCT TCACAGCTGG 
GAAGCTCCTG GCCTTGGCCC TGATTATCAT CATGGGGATT GTACAGATAT GCAAAGGAAC 
CTTCCCAGAG CCATCTTCAT CTCCATCCCA CTGGTCACAT TTGTGTATGT CTTTGCCAAT 
GTCGCTTATG TCACTGCAAT GTCCCCCCAG GAGCTGCTGG CATCCAACGC CGTCGCTGTG 
ACTTTTGGAG AGAAGCTCCT AGGAGTCATG GCCTGGATCA TGCCCATTTC TGTTGCCCTG 
TCCACATTTG GAGGAGTTAA TGGGTCTCTC TTCACCTCCT CTCGGCTGTT CTTCGCTGGA 
GCCCGAGAGG GCCACCTTCC CAGTGTGTTG GCCATGATCC ACGTGAAGCG CTGCACCCCA 
ATCCCAGCCC TGCTCTTCAC ATGCATCTCC ACCCTGCTGA TGCTGGTCAC CAGCGACATG 
TACACACTCA TCAACTATGT GGGCTTCATC AACTACCTCT TCTATGGGGT CACGGTTGCT 
GGACAGATAG TCCTTCGCTG GAAGAAGCCT GATATCCCCC GCCCCATCAA GATCAACCTG 
CTGTTCCCCA TCATCTACTT GCTGTTCTGG GCCTTCCTGC TGGTCTTCAG CCTGTGGTCA 
GAGCCGGTGG TGTGTGGCAT TGGCCTGGCC ATCATGCTGA CAGGAGTGCC TGTCTATTTC 
CTGGGTGTTT ACTGGCAACA CAAGCCCAAG TGTTTCAGTG ACTTCATTGA GCTGCTAACC 
CTGGTGAGCC AGAAGATGTG TGTGGTCGTG TACCCCGAGG TGGAGCGGGG CTCAGGGACA 
GAGGAGGCTA ATGAGGACAT GGAGGAGCAG CAGCAGCCCA TGTACCAACC CACTCCCACG 
AAGGACAAGG ACGTGGCGGG GCAGCCCCAG CCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001253966.1
CDS	203..1138
Translation	MGQLFQCAVGHPGSRHLHSWEAPGLGPDYHHGDCTDMQRNLPRAIFISIPLVTFVYVFANVAYVTAMSPQELLASNAVAVTFGEKLLGVMAWIMPISVALSTFGGVNGSLFTSSRLFFAGAREGHLPSVLAMIHVKRCTPIPALLFTCISTLLMLVTSDMYTLINYVGFINYLFYGVTVAGQIVLRWKKPDIPRPIKINLLFPIIYLLFWAFLLVFSLWSEPVVCGIGLAIMLTGVPVYFLGVYWQHKPKCFSDFIELLTLVSQKMCVVVYPEVERGSGTEEANEDMEEQQQPMYQPTPTKDKDVAGQPQP

Target ORF information:

RefSeq Version	NM_001267037.1
Organism	Homo sapiens(human)
Definition	Homo sapiens solute carrier family 7 member 8 (SLC7A8), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001267037.1

ORF Insert Sequence:

ATGGGTCAAC TGTTCCAGTG TGCGGTGGGC CACCCGGGTT CAAGACATCT TCACAGCTGG 
GAAGCTCCTG GCCTTGGCCC TGATTATCAT CATGGGGATT GTACAGATAT GCAAAGGAAC 
CTTCCCAGAG CCATCTTCAT CTCCATCCCA CTGGTCACAT TTGTGTATGT CTTTGCCAAT 
GTCGCTTATG TCACTGCAAT GTCCCCCCAG GAGCTGCTGG CATCCAACGC CGTCGCTGTG 
ACTTTTGGAG AGAAGCTCCT AGGAGTCATG GCCTGGATCA TGCCCATTTC TGTTGCCCTG 
TCCACATTTG GAGGAGTTAA TGGGTCTCTC TTCACCTCCT CTCGGCTGTT CTTCGCTGGA 
GCCCGAGAGG GCCACCTTCC CAGTGTGTTG GCCATGATCC ACGTGAAGCG CTGCACCCCA 
ATCCCAGCCC TGCTCTTCAC ATGCATCTCC ACCCTGCTGA TGCTGGTCAC CAGCGACATG 
TACACACTCA TCAACTATGT GGGCTTCATC AACTACCTCT TCTATGGGGT CACGGTTGCT 
GGACAGATAG TCCTTCGCTG GAAGAAGCCT GATATCCCCC GCCCCATCAA GATCAACCTG 
CTGTTCCCCA TCATCTACTT GCTGTTCTGG GCCTTCCTGC TGGTCTTCAG CCTGTGGTCA 
GAGCCGGTGG TGTGTGGCAT TGGCCTGGCC ATCATGCTGA CAGGAGTGCC TGTCTATTTC 
CTGGGTGTTT ACTGGCAACA CAAGCCCAAG TGTTTCAGTG ACTTCATTGA GCTGCTAACC 
CTGGTGAGCC AGAAGATGTG TGTGGTCGTG TACCCCGAGG TGGAGCGGGG CTCAGGGACA 
GAGGAGGCTA ATGAGGACAT GGAGGAGCAG CAGCAGCCCA TGTACCAACC CACTCCCACG 
AAGGACAAGG ACGTGGCGGG GCAGCCCCAG CCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Mutations in L-type amino acid transporter-2 support
eLife7(2018 Jan)
Espino Gaurch M,Font-Llitj?s M,Murillo-Cuesta S,Errasti-Murugarren E,Celaya AM,Girotto G,Vuckovic D,Mezzavilla M,Vilches C,Bodoy S,Sah?n I,Gonz?lez L,Prat E,Zorzano A,Dierssen M,Varela-Nieto I,Gasparini P,Palac?n M,Nunes V

Overexpression of L-Type Amino Acid Transporter 1 (LAT1) and 2 (LAT2): Novel Markers of Neuroendocrine Tumors.
PloS one11(5)e0156044(2016)
Barollo S,Bertazza L,Watutantrige-Fernando S,Censi S,Cavedon E,Galuppini F,Pennelli G,Fassina A,Citton M,Rubin B,Pezzani R,Benna C,Opocher G,Iacobone M,Mian C

Expression and functional characterisation of System L amino acid transporters in the human term placenta.
Reproductive biology and endocrinology : RB&E1357(2015 Jun)
Gaccioli F,Aye IL,Roos S,Lager S,Ramirez VI,Kanai Y,Powell TL,Jansson T

Detergent-induced stabilization and improved 3D map of the human heteromeric amino acid transporter 4F2hc-LAT2.
PloS one9(10)e109882(2014)
Meury M,Costa M,Harder D,Stauffer M,Jeckelmann JM,Br?hlmann B,Rosell A,Ilg? H,Kovar K,Palac?n M,Fotiadis D

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SLC7A8 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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