Gene Symbol | Rnf212 |
Entrez Gene ID | 671564 |
Full Name | ring finger protein 212 |
Synonyms | EG330157,F830003B07,repro57 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Rnf212 cDNA ORF clone
gRNAs
Gene Symbol | Rnf212 |
Entrez Gene ID | 671564 |
Full Name | ring finger protein 212 |
Synonyms | EG330157,F830003B07,repro57 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_006535331.3 | XP_006535394.1 | probable E3 SUMO-protein ligase RNF212 isoform X1 |
XM_006535331.4 | XP_006535394.1 | probable E3 SUMO-protein ligase RNF212 isoform X1 |
NM_001362887.1 | NP_001349816.1 | probable E3 SUMO-protein ligase RNF212 |
XM_006535332.3 | XP_006535395.1 | probable E3 SUMO-protein ligase RNF212 isoform X2 |
LOC100424020 | XP_002802326.1 | |
Homo sapiens (human) | RNF212 | NP_919420.1 |
Rattus norvegicus (Norway rat) | Rnf212 | XP_006250649.1 |
Danio rerio (zebrafish) | LOC100534793 | XP_003199908.2 |
Canis lupus familiaris (dog) | RNF212 | XP_005618730.1 |
Mus musculus (house mouse) | Rnf212 | XP_006535394.1 |
Xenopus tropicalis (tropical clawed frog) | rnf212 | XP_004911535.1 |
Bos taurus (cattle) | RNF212 | XP_005208343.1 |
Gallus gallus (chicken) | RNF212 | XP_004936293.1 |
Genetics of Genome-Wide Recombination Rate Evolution in Mice from an Isolated Island.
Wang RJ, Payseur BA
Genetics206(4)1841-1852(2017 08)
A SUMO-ubiquitin relay recruits proteasomes to chromosome axes to regulate meiotic recombination.
Rao HB, Qiao H, Bhatt SK, Bailey LR, Tran HD, Bourne SL, Qiu W, Deshpande A, Sharma AN, Beebout CJ, Pezza RJ, Hunter N
Science (New York, N.Y.)355(6323)403-407(2017 01)
An ENU-induced mutation in the mouse Rnf212 gene is associated with male meiotic failure and infertility.
Fujiwara Y, Matsumoto H, Akiyama K, Srivastava A, Chikushi M, Ann Handel M, Kunieda T
Reproduction (Cambridge, England)149(1)67-74(2015 Jan)
Antagonistic roles of ubiquitin ligase HEI10 and SUMO ligase RNF212 regulate meiotic recombination.
Qiao H, Prasada Rao HB, Yang Y, Fong JH, Cloutier JM, Deacon DC, Nagel KE, Swartz RK, Strong E, Holloway JK, Cohen PE, Schimenti J, Ward J, Hunter N
Nature genetics46(2)194-9(2014 Feb)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Interdependent localization of SUMO, ubiquitin, and proteasomes along chromosome axes was mediated largely by RNF212 and HEI10, two E3 ligases that are also essential for crossover recombination.
Title: A SUMO-ubiquitin relay recruits proteasomes to chromosome axes to regulate meiotic recombination.
Mutation in the mouse Rnf212 gene is associated with male meiotic failure and infertility.
Title: An ENU-induced mutation in the mouse Rnf212 gene is associated with male meiotic failure and infertility.
Antagonistic roles of ubiquitin ligase HEI10 and SUMO ligase RNF212 regulate meiotic recombination.
Title: Antagonistic roles of ubiquitin ligase HEI10 and SUMO ligase RNF212 regulate meiotic recombination.
We show that mouse RNF212 is essential for crossing-over, functioning to couple chromosome synapsis to the formation of crossover-specific recombination complexes
Title: RNF212 is a dosage-sensitive regulator of crossing-over during mammalian meiosis.
The following Rnf212 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Rnf212 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu35749 | |
Clone ID Related Accession (Same CDS sequence) | XM_006535331.3 , XM_006535331.4 | |
Accession Version | XM_006535331.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 948bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | probable E3 SUMO-protein ligase RNF212 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000071.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006535331.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCCAGCT GGGTGTTCTG TAATCGCTGT TTCCAGTCGC CGCACAGGAA GTCGTCCTTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006535394.1 |
CDS | 133..1080 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006535331.3 |
1 | ATGGCCAGCT GGGTGTTCTG TAATCGCTGT TTCCAGTCGC CGCACAGGAA GTCGTCCTTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu35750 | |
Clone ID Related Accession (Same CDS sequence) | XM_006535332.3 | |
Accession Version | XM_006535332.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 585bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | probable E3 SUMO-protein ligase RNF212 isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000071.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006535332.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAGATCAT CACAACAACC AGCTTTCAAC AAAATCAAAA ATTCAGTTTC AACAAAGCCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006535395.1 |
CDS | 448..1032 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006535332.3 |
1 | ATGAGATCAT CACAACAACC AGCTTTCAAC AAAATCAAAA ATTCAGTTTC AACAAAGCCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu84149 | |
Clone ID Related Accession (Same CDS sequence) | NM_001362887.1 | |
Accession Version | NM_001362887.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 924bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-24 | |
Organism | Mus musculus(house mouse) | |
Product | probable E3 SUMO-protein ligase RNF212 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC123743.11. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849376 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## inferred exon combination :: based on alignments, homology ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGCCAGCT GGGTGTTCTG TAATCGCTGT TTCCAGTCGC CGCACAGGAA GTCGTCCTTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001349816.1 |
CDS | 46..969 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001362887.1 |
1 | ATGGCCAGCT GGGTGTTCTG TAATCGCTGT TTCCAGTCGC CGCACAGGAA GTCGTCCTTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu35749 | |
Clone ID Related Accession (Same CDS sequence) | XM_006535331.3 , XM_006535331.4 | |
Accession Version | XM_006535331.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 948bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | probable E3 SUMO-protein ligase RNF212 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000071.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006535331.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCCAGCT GGGTGTTCTG TAATCGCTGT TTCCAGTCGC CGCACAGGAA GTCGTCCTTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006535394.1 |
CDS | 86..1033 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006535331.4 |
1 | ATGGCCAGCT GGGTGTTCTG TAATCGCTGT TTCCAGTCGC CGCACAGGAA GTCGTCCTTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genetics of Genome-Wide Recombination Rate Evolution in Mice from an Isolated Island. |
A SUMO-ubiquitin relay recruits proteasomes to chromosome axes to regulate meiotic recombination. |
An ENU-induced mutation in the mouse Rnf212 gene is associated with male meiotic failure and infertility. |
Antagonistic roles of ubiquitin ligase HEI10 and SUMO ligase RNF212 regulate meiotic recombination. |