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OPA3 cDNA ORF clone, Homo sapiens (human)

Gene Symbol OPA3
Entrez Gene ID 80207
Full Name optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
Synonyms MGA3
General protein information
Preferred Names
optic atrophy 3 protein
Names
optic atrophy 3 protein
Optic atrophy 3 (Iraqi-Jewish 'optic atrophy plus')
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

19

19q13.32

Summary The mouse ortholog of this protein co-purifies with the mitochondrial inner membrane. Mutations in this gene have been shown to result in 3-methylglutaconic aciduria type III and autosomal dominant optic atrophy and cataract. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]. lac of sum
Disorder MIM:

606580

Disorder Html: 3-methylglutaconic aciduria, type III, 258501 (3); Optic atrophy

mRNA and Protein(s)

mRNA Protein Name
XM_011527348 XP_011525650 optic atrophy 3 protein isoform X1
XM_006723403 XP_006723466 optic atrophy 3 protein isoform X2
XM_005259278 XP_005259335 optic atrophy 3 protein isoform X2
NM_001017989 NP_001017989 optic atrophy 3 protein isoform a
NM_025136 NP_079412 optic atrophy 3 protein isoform b


Homo sapiens (human) OPA3 NP_001017989.2
Canis lupus familiaris (dog) OPA3 XP_855096.1
Bos taurus (cattle) OPA3 NP_001232863.1
Mus musculus (house mouse) Opa3 NP_997408.2
Danio rerio (zebrafish) opa3 NP_001073635.1
Drosophila melanogaster (fruit fly) CG13601 NP_001262890.1
Xenopus (Silurana) tropicalis (western clawed frog) opa3 XP_002932648.1


GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following OPA3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the OPA3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu72660 XM_011527348 PREDICTED: Homo sapiens optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) (OPA3), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $69.30
$99.00
OHu52502 XM_006723403 PREDICTED: Homo sapiens optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) (OPA3), transcript variant X2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $69.30
$99.00
OHu52502 XM_005259278 PREDICTED: Homo sapiens optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) (OPA3), transcript variant X3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $69.30
$99.00
OHu19423
NM_001017989 Homo sapiens optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) (OPA3), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$49.50-$69.30
$99.00
OHu23186 NM_025136 Homo sapiens optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) (OPA3), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $69.30
$99.00
Next-day Shipping ORF Clones ( in default vector with tag)
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*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu72660
Clone ID Related Accession (Same CDS sequence) XM_011527348
Accession Version XM_011527348.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 384bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product optic atrophy 3 protein isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_011109.17) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
ATGCGGACCA AAATGCGCAT CATGGGTTTC AATGCCGCTG CCATCAAGCC GCTGAACGAG 
GGTGCAGCCG CCGAGCTGGG CGCGGAGCTG CTGGGCGAGG GCATCATCTT CATCACCGCC
TGCAGCTGCC TGATGCTGGA GTATTGGCGC CACCAGTTGC AGCAGCGCCG CAAGGAAAAG
GAGCGACGTG TTGCCAGGGA GGCGCTGCGG GGCGAGGTGG GCCACTTGGG GCTGGCGCTC
GAGGAGTTGC AGGCGCAGGT GCAGGCGACG TCGACGCAGC TCGCCCTGGA GGAGCTGCGC
GCTCAGCTGC AGGAGGTGCG AGCCCACCTC TGCCTCCGAG ACCCGCCGCC TGCACCCCCA
GTTGCGCCGG CGTCCGAGAA ATAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011525650.1
CDS290..673
Misc Feature(1)290..547(+)
Translation

Target ORF information:

RefSeq Version XM_011527348
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) (OPA3), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011527348

ORF Insert Sequence:

1
61
121
181
241
301
361
ATGCGGACCA AAATGCGCAT CATGGGTTTC AATGCCGCTG CCATCAAGCC GCTGAACGAG 
GGTGCAGCCG CCGAGCTGGG CGCGGAGCTG CTGGGCGAGG GCATCATCTT CATCACCGCC
TGCAGCTGCC TGATGCTGGA GTATTGGCGC CACCAGTTGC AGCAGCGCCG CAAGGAAAAG
GAGCGACGTG TTGCCAGGGA GGCGCTGCGG GGCGAGGTGG GCCACTTGGG GCTGGCGCTC
GAGGAGTTGC AGGCGCAGGT GCAGGCGACG TCGACGCAGC TCGCCCTGGA GGAGCTGCGC
GCTCAGCTGC AGGAGGTGCG AGCCCACCTC TGCCTCCGAG ACCCGCCGCC TGCACCCCCA
GTTGCGCCGG CGTCCGAGAA ATAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu52502
Clone ID Related Accession (Same CDS sequence) XM_005259278 , XM_006723403
Accession Version XM_006723403.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 381bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product optic atrophy 3 protein isoform X2
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_011109.17) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 12, 2015 this sequence version replaced gi:578834945. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
ATGCGGACCA AGATGCGCAT CATGGGCTTC CGGGGCACGG TCATCAAGCC GCTGAACGAG 
GAGGCGGCAG CTGAGCTGGG CGCAGAGCTG CTGGGCGAAG CCACCATCTT CATCGTGGGC
GGCGGCTGCC TAGTGCTGGA GTACTGGCGC CACCAGGCGC AGCAGCGCCA CAAGGAGGAG
GAGCAGCGTG CTGCCTGGAA CGCGCTGCGG GACGAGGTGG GCCACCTGGC GCTGGCGCTG
GAAGCGCTGC AGGCGCAGGT GCAGGCGGCG CCGCCACAGG GCGCCCTGGA GGAACTGCGC
ACAGAGCTGC AAGAGGTGCG CGCCCAGCTC TGCAATCCCG GCCGGTCCGC TTCCCACGCA
GTGCCTGCGT CCAAGAAATA G

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_006723466.1
CDS236..616
Misc Feature(1)236..457(+)
Translation

Target ORF information:

RefSeq Version XM_006723403
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) (OPA3), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_006723403

ORF Insert Sequence:

1
61
121
181
241
301
361
ATGCGGACCA AGATGCGCAT CATGGGCTTC CGGGGCACGG TCATCAAGCC GCTGAACGAG 
GAGGCGGCAG CTGAGCTGGG CGCAGAGCTG CTGGGCGAAG CCACCATCTT CATCGTGGGC
GGCGGCTGCC TAGTGCTGGA GTACTGGCGC CACCAGGCGC AGCAGCGCCA CAAGGAGGAG
GAGCAGCGTG CTGCCTGGAA CGCGCTGCGG GACGAGGTGG GCCACCTGGC GCTGGCGCTG
GAAGCGCTGC AGGCGCAGGT GCAGGCGGCG CCGCCACAGG GCGCCCTGGA GGAACTGCGC
ACAGAGCTGC AAGAGGTGCG CGCCCAGCTC TGCAATCCCG GCCGGTCCGC TTCCCACGCA
GTGCCTGCGT CCAAGAAATA G

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu52502
Clone ID Related Accession (Same CDS sequence) XM_005259278 , XM_006723403
Accession Version XM_005259278.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 381bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product optic atrophy 3 protein isoform X2
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_011109.17) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 12, 2015 this sequence version replaced gi:530417294. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
ATGCGGACCA AGATGCGCAT CATGGGCTTC CGGGGCACGG TCATCAAGCC GCTGAACGAG 
GAGGCGGCAG CTGAGCTGGG CGCAGAGCTG CTGGGCGAAG CCACCATCTT CATCGTGGGC
GGCGGCTGCC TAGTGCTGGA GTACTGGCGC CACCAGGCGC AGCAGCGCCA CAAGGAGGAG
GAGCAGCGTG CTGCCTGGAA CGCGCTGCGG GACGAGGTGG GCCACCTGGC GCTGGCGCTG
GAAGCGCTGC AGGCGCAGGT GCAGGCGGCG CCGCCACAGG GCGCCCTGGA GGAACTGCGC
ACAGAGCTGC AAGAGGTGCG CGCCCAGCTC TGCAATCCCG GCCGGTCCGC TTCCCACGCA
GTGCCTGCGT CCAAGAAATA G

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_005259335.1
CDS104..484
Misc Feature(1)104..325(+)
Translation

Target ORF information:

RefSeq Version XM_005259278
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) (OPA3), transcript variant X3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_005259278

ORF Insert Sequence:

1
61
121
181
241
301
361
ATGCGGACCA AGATGCGCAT CATGGGCTTC CGGGGCACGG TCATCAAGCC GCTGAACGAG 
GAGGCGGCAG CTGAGCTGGG CGCAGAGCTG CTGGGCGAAG CCACCATCTT CATCGTGGGC
GGCGGCTGCC TAGTGCTGGA GTACTGGCGC CACCAGGCGC AGCAGCGCCA CAAGGAGGAG
GAGCAGCGTG CTGCCTGGAA CGCGCTGCGG GACGAGGTGG GCCACCTGGC GCTGGCGCTG
GAAGCGCTGC AGGCGCAGGT GCAGGCGGCG CCGCCACAGG GCGCCCTGGA GGAACTGCGC
ACAGAGCTGC AAGAGGTGCG CGCCCAGCTC TGCAATCCCG GCCGGTCCGC TTCCCACGCA
GTGCCTGCGT CCAAGAAATA G

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu19423
Clone ID Related Accession (Same CDS sequence) NM_001017989
Accession Version NM_001017989.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 543bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product optic atrophy 3 protein isoform a
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB034102.1, BC047316.1 and AC006117.1. This sequence is a reference standard in the RefSeqGene project. On Aug 22, 2007 this sequence version replaced gi:63055069. Transcript Variant: This variant (1) uses an alternate splice site resulting in a distinct 3' coding region and 3' UTR, compared to variant 2. The resulting isoform (a) has a longer and distinct C-terminus, compared to isoform b. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##RefSeq-Attributes-START## gene product(s) localized to mito. :: PMID: 18614015, 12865426; reported by MitoCarta ##RefSeq-Attributes-END## ##Evidence-Data-START## Transcript exon combination :: BC047316.1, AK098798.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968189, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

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481
541
ATGGTGGTGG GCGCGTTCCC TATGGCGAAG CTGCTATACT TGGGCATCCG GCAGGTCAGC 
AAGCCGCTTG CCAACCGTAT TAAGGAGGCC GCCCGCCGAA GCGAGTTCTT CAAGACCTAT
ATCTGCCTCC CGCCGGCTCA ACTGTACCAC TGGCTGGAGA TGCGGACCAA AATGCGCATC
ATGGGTTTCA ATGCCGCTGC CATCAAGCCG CTGAACGAGG GTGCAGCCGC CGAGCTGGGC
GCGGAGCTGC TGGGCGAGGG CATCATCTTC ATCACCGCCT GCAGCTGCCT GATGCTGGAG
TATTGGCGCC ACCAGTTGCA GCAGCGCCGC AAGGAAAAGG AGCGACGTGT TGCCAGGGAG
GCGCTGCGGG GCGAGGTGGG CCACTTGGGG CTGGCGCTCG AGGAGTTGCA GGCGCAGGTG
CAGGCGACGT CGACGCAGCT CGCCCTGGAG GAGCTGCGCG CTCAGCTGCA GGAGGTGCGA
GCCCACCTCT GCCTCCGAGA CCCGCCGCCT GCACCCCCAG TTGCGCCGGC GTCCGAGAAA
TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001017989.2
CDS101..643
Misc Feature(1)119..517(+)
Exon (1)1..242
Gene:OPA3
Gene Synonym:
Exon (2)243..1932
Gene:OPA3
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001017989
Organism Homo sapiens (human)
Definition Homo sapiens optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) (OPA3), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001017989

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
ATGGTGGTGG GCGCGTTCCC TATGGCGAAG CTGCTATACT TGGGCATCCG GCAGGTCAGC 
AAGCCGCTTG CCAACCGTAT TAAGGAGGCC GCCCGCCGAA GCGAGTTCTT CAAGACCTAT
ATCTGCCTCC CGCCGGCTCA ACTGTACCAC TGGCTGGAGA TGCGGACCAA AATGCGCATC
ATGGGTTTCA ATGCCGCTGC CATCAAGCCG CTGAACGAGG GTGCAGCCGC CGAGCTGGGC
GCGGAGCTGC TGGGCGAGGG CATCATCTTC ATCACCGCCT GCAGCTGCCT GATGCTGGAG
TATTGGCGCC ACCAGTTGCA GCAGCGCCGC AAGGAAAAGG AGCGACGTGT TGCCAGGGAG
GCGCTGCGGG GCGAGGTGGG CCACTTGGGG CTGGCGCTCG AGGAGTTGCA GGCGCAGGTG
CAGGCGACGT CGACGCAGCT CGCCCTGGAG GAGCTGCGCG CTCAGCTGCA GGAGGTGCGA
GCCCACCTCT GCCTCCGAGA CCCGCCGCCT GCACCCCCAG TTGCGCCGGC GTCCGAGAAA
TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu23186
Clone ID Related Accession (Same CDS sequence) NM_025136
Accession Version NM_025136.3 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 540bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product optic atrophy 3 protein isoform b
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB034102.1, BC005059.1, AC006261.1 and BU617706.1. On Oct 8, 2009 this sequence version replaced gi:156151425. Transcript Variant: This variant (2) represents the longer transcript but encodes the shorter isoform (b). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##RefSeq-Attributes-START## gene product(s) localized to mito. :: PMID: 18614015, 12865426; reported by MitoCarta ##RefSeq-Attributes-END## ##Evidence-Data-START## Transcript exon combination :: AK025840.1, BC005059.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2142670, SAMEA2154405 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

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ATGGTGGTGG GCGCGTTCCC TATGGCGAAG CTGCTATACT TGGGCATCCG GCAGGTCAGC 
AAGCCGCTTG CCAACCGTAT TAAGGAGGCC GCCCGCCGAA GCGAGTTCTT CAAGACCTAT
ATCTGCCTCC CGCCGGCTCA ACTGTATCAC TGGGTGGAGA TGCGGACCAA GATGCGCATC
ATGGGCTTCC GGGGCACGGT CATCAAGCCG CTGAACGAGG AGGCGGCAGC TGAGCTGGGC
GCAGAGCTGC TGGGCGAAGC CACCATCTTC ATCGTGGGCG GCGGCTGCCT AGTGCTGGAG
TACTGGCGCC ACCAGGCGCA GCAGCGCCAC AAGGAGGAGG AGCAGCGTGC TGCCTGGAAC
GCGCTGCGGG ACGAGGTGGG CCACCTGGCG CTGGCGCTGG AAGCGCTGCA GGCGCAGGTG
CAGGCGGCGC CGCCACAGGG CGCCCTGGAG GAACTGCGCA CAGAGCTGCA AGAGGTGCGC
GCCCAGCTCT GCAATCCCGG CCGGTCCGCT TCCCACGCAG TGCCTGCGTC CAAGAAATAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_079412.1
CDS101..640
Misc Feature(1)119..481(+)
Exon (1)1..242
Gene:OPA3
Gene Synonym:
Exon (2)243..7873
Gene:OPA3
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_025136
Organism Homo sapiens (human)
Definition Homo sapiens optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) (OPA3), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_025136

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
ATGGTGGTGG GCGCGTTCCC TATGGCGAAG CTGCTATACT TGGGCATCCG GCAGGTCAGC 
AAGCCGCTTG CCAACCGTAT TAAGGAGGCC GCCCGCCGAA GCGAGTTCTT CAAGACCTAT
ATCTGCCTCC CGCCGGCTCA ACTGTATCAC TGGGTGGAGA TGCGGACCAA GATGCGCATC
ATGGGCTTCC GGGGCACGGT CATCAAGCCG CTGAACGAGG AGGCGGCAGC TGAGCTGGGC
GCAGAGCTGC TGGGCGAAGC CACCATCTTC ATCGTGGGCG GCGGCTGCCT AGTGCTGGAG
TACTGGCGCC ACCAGGCGCA GCAGCGCCAC AAGGAGGAGG AGCAGCGTGC TGCCTGGAAC
GCGCTGCGGG ACGAGGTGGG CCACCTGGCG CTGGCGCTGG AAGCGCTGCA GGCGCAGGTG
CAGGCGGCGC CGCCACAGGG CGCCCTGGAG GAACTGCGCA CAGAGCTGCA AGAGGTGCGC
GCCCAGCTCT GCAATCCCGG CCGGTCCGCT TCCCACGCAG TGCCTGCGTC CAAGAAATAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

 
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