Catalog Products » Antibodies » Primary Antibodies » Anti-idiotype Antibody Products

Overview

Idiotypes are antigenic determinants located in the variable region of antibodies. An anti-idiotype antibody can specifically bind to an idiotype of another antibody, usually an antibody drug. Hence, anti-idiotype antibodies can be used in preclinical practices for pharmacokinetic (PK) analysis to measure antibody drug levels. Since an anti-idotype antibody is very similar to an anti-drug antibody (ADA), anti-idiotype antibodies can also be used as positive controls for immunogenicity assays.

GenScript has developed a broad range of off-the-shelf anti-idiotype antibodies against blockbuster drugs to help accelerate your research of biosimilars.

Benefits

100+ Products

Against 28 monoclonal antibody drugs

Ready-to-use Anti-ID Pairs

Various pre-validated anti-ID pairs for PK study

High Sensitivity MonoRab™ mAb

Perfect for picomolar-level immunoassay

Antibodies and Immunodetection

Product Overview

Anti-Adalimumab/Humira (Target‎: ‎TNF alpha)

Cat. No. Product Name Inhibitory IC50 (μg/ml) Recommend Applications Recommended Pairs (Capture-Detection) Order
A01954-40 Anti-Adalimumab Antibody (15C7), mAb, Mouse 0.258 ELISA, PK study A01954-40 (C) - A01955-40 (D)
A01954-40 (C) - A01956-40 (D)
 
A01955-40 Anti-Adalimumab Antibody (3C2), mAb, Mouse Non-inhibitory ELISA, PK study
 
A01956-40 Anti-Adalimumab Antibody (3C2) [Biotin], mAb, Mouse - ELISA, PK study
 
A01921-40 MonoRab™ Anti-Adalimumab Antibody (4E12), mAb, Rabbit 0.175 ELISA, PK study A01921-40 (C) - A01922-40 (D)
 
A01922-40 MonoRab™ Anti-Adalimumab Antibody (134D5), mAb, Rabbit 0.353 ELISA, PK study
 
A01923-40 MonoRab™ Anti-Adalimumab Antibody (196F3), mAb, Rabbit Non-inhibitory ELISA, PK study -
 
A01886-40 Anti-Adalimumab Antibody, pAb, Rabbit - ELISA, Immunogenicity assay -
 

Anti-Atezolizumab/Tecentriq (Target‎: ‎PD-L1)

Cat. No. Product Name Inhibitory IC50 (μg/ml) Recommend Applications Recommended Pairs (Capture-Detection) Order
A01948-40 Anti-Atezolizumab Antibody (10G9), mAb, Mouse 0.118 ELISA, PK study A01948-40 (C) - A01949-40 (D)
A01948-40 (C) - A01950-40 (D)
 
A01949-40 Anti-Atezolizumab Antibody (6B12), mAb, Mouse Non-inhibitory ELISA, PK study
 
A01950-40 Anti-Atezolizumab Antibody (6B12) [Biotin], mAb, Mouse - ELISA, PK study
 
A01984-40 MonoRab™ Anti-Atezolizumab Antibody (55D8) mAb, Rabbit 0.391 ELISA, PK study A01984-40 (C) - A01985-40 (D)
A01984-40 (C) - A01986-40 (D)
 
A01985-40 MonoRab™ Anti-Atezolizumab Antibody (43H11), mAb, Rabbit 0.847 ELISA, PK study
 
A01986-40 MonoRab™ Anti-Atezolizumab Antibody (43H11)[Biotin], mAb, Rabbit - ELISA, PK study
 

Anti-Avelumab/Bavencio (Target: ‎PD-L1)

Cat. No. Product Name Inhibitory IC50 (μg/ml) Recommend Applications Recommended Pairs (Capture-Detection) Order
A02121-40 Anti-Avelumab Antibody (12H7), mAb, Mouse 0.748 ELISA, PK study A02121-40 (C) - A02120-40 (D)
 
A02120-40 Anti-Avelumab Antibody (12G9), mAb, Mouse 0.741 ELISA, PK study
 

Anti-Bevacizumab/Avastin (Target: VEGF-A)

Cat. No. Product Name Inhibitory IC50 (μg/ml) Recommend Applications Recommended Pairs (Capture-Detection) Order
A01975-40 Anti-Bevacizumab Antibody (4H1), mAb, Mouse Non-inhibitory ELISA, PK study A01975-40 (C) - A01976-40 (D)
A01975-40 (C) - A01977-40 (D)
 
A01976-40 Anti-Bevacizumab Antibody (6C3), mAb, Mouse 0.157 ELISA, PK study
 
A01977-40 Anti-Bevacizumab Antibody (6C3)[Biotin], mAb, Mouse - ELISA, PK study
 
A02185-40 Anti-Bevacizumab Antibody (11C1), mAb, Mouse Non-inhibitory ELISA, PK study A02185-40 (C) - A01962-40 (D)
A02185-40 (C) - A01896-40 (D)
 
A01895-40 MonoRab™ Anti-Bevacizumab Antibody (30E1), mAb, Rabbit Non-inhibitory ELISA, PK study A01895-40 (C) - A01962-40 (D)
A01895-40 (C) - A01896-40 (D)
 
A01962-40 MonoRab™ Anti-Bevacizumab Antibody (46E3), mAb, Rabbit 0.046 ELISA, PK study
 
A01896-40 MonoRab™ Anti-Bevacizumab Antibody (46E3)[Biotin], mAb, Rabbit - ELISA, PK study
 
A01887-40 Anti-Bevacizumab Antibody, pAb, Rabbit - ELISA, Immunogenicity assay -
 

Anti-Cetuximab/Erbitux (Target: EGF Receptor)

Cat. No. Product Name Inhibitory IC50 (μg/ml) Recommend Applications Recommended Pairs (Capture-Detection) Order
A01939-40 Anti-Cetuximab Antibody (20H1), mAb, Mouse Non-inhibitory ELISA, PK study A01939-40 (C) - A01938-40 (D) 
 
A01938-40 Anti-Cetuximab Antibody (18D5), mAb, Mouse 0.2073 ELISA, PK study
 
A01991-40 MonoRab™ Anti-Cetuximab Antibody (69H10), mAb, Rabbit 0.039 ELISA, PK study A01991-40 (C) - A01992-40 (D)
 
A01992-40 MonoRab™ Anti-Cetuximab Antibody (90G3), mAb, Rabbit 0.015 ELISA, PK study
 

Anti-Daratumumab/Darzalex (Target: CD38)

Cat. No. Product Name Inhibitory IC50 (μg/ml) Recommend Applications Recommended Pairs (Capture-Detection) Order
A01996-40 Anti-Daratumumab Antibody (11F2), mAb, Mouse Non-inhibitory ELISA, PK study A01996-40 (C) - A01997-40 (D)
 
A01997-40 Anti-Daratumumab Antibody (6A3), mAb, Mouse 0.582 ELISA, PK study
 
A01998-40 Anti-Daratumumab Antibody (9A6), mAb, Mouse 0.118 ELISA, PK study -
 
A02009-40 MonoRab™ Anti-Daratumumab(139B10), mAb, Rabbit 0.017 ELISA, PK study -
 

Anti-Denosumab/Prolia (Target: RANK Ligand)

Cat. No. Product Name Inhibitory IC50 (μg/ml) Recommend Applications Recommended Pairs (Capture-Detection) Order
A02229-40 Anti-Denosumab Antibody (3B1), mAb, Mouse 1.02 ELISA, PK study A02229-40 (C) - A02230-40 (D)
 
A02230-40 Anti-Denosumab Antibody (16F2), mAb, Mouse 0.11 ELISA, PK study
 
A02101-40 Anti-Denosumab Antibody (2H7), mAb, Mouse Non-inhibitory ELISA, PK study A02101-40 (C) - A02102-40 (D)
 
A02102-40 Anti-Denosumab Antibody (9A10), mAb, Mouse 0.893 ELISA, PK study
 

Anti-Dupilumab/Dupixent (Target: IL-4Rα)

Cat. No. Product Name Inhibitory IC50 (μg/ml) Recommend Applications Recommended Pairs (Capture-Detection) Order
A02098-40 Anti-Dupilumab Antibody (6C9), mAb, Mouse 0.185 ELISA, PK study A02098-40 (C) - A02097-40 (D)
 
A02097-40 Anti-Dupilumab Antibody (2D5), mAb, Mouse 0.174 ELISA, PK study
 

Anti-Durvalumab/Imfinzi (Target: CD274)

Cat. No. Product Name Inhibitory IC50 (μg/ml) Recommend Applications Recommended Pairs (Capture-Detection) Order
A02031-40 Anti-Durvalumab Antibody (15D6), mAb, Mouse 1.37 ELISA, PK study -
 

Anti-Eculizumab/Soliris (Target: ‎Complement protein C5)

Cat. No. Product Name Inhibitory IC50 (μg/ml) Recommend Applications Recommended Pairs (Capture-Detection) Order
A02115-40 Anti-Eculizumab Antibody (4F6), mAb, Mouse Non-inhibitory ELISA, PK study A02115-40 (C) - A02116-40 (D)
 
A02116-40  Anti-Eculizumab Antibody(13F5), mAb, Mouse 1.053 ELISA, PK study
 

Anti-Etanercept/Enbrel (Target: ‎TNF alpha)

Cat. No. Product Name Inhibitory IC50 (μg/ml) Recommend Applications Recommended Pairs (Capture-Detection) Order
A02114-40 Anti-Etanercept Antibody (4H5), mAb, Mouse 0.467 ELISA, PK study A02114-40 (C) - A02113-40 (D)
 
A02113-40 Anti-Etanercept Antibody (4H1), mAb, Mouse Non-inhibitory ELISA, PK study
 

Anti-Golimumab/Simponi (Target: ‎TNF alpha)

Cat. No. Product Name Inhibitory IC50 (μg/ml) Recommend Applications Recommended Pairs (Capture-Detection) Order
A02093-40 Anti-Golimumab Antibody, pAb, Rabbit - ELISA, Immunogenicity assay -
 

Anti-Infliximab/Remicade (Target: TNF alpha)

Cat. No. Product Name Inhibitory IC50 (μg/ml) Recommend Applications Recommended Pairs (Capture-Detection) Order
A02040-40 Anti-Infliximab Antibody (27A4) , mAb, Mouse Non-inhibitory ELISA, PK study A02040-40 (C) - A02041-40 (D)
 
A02041-40 Anti-Infliximab Antibody (23H5) , mAb, Mouse Non-inhibitory ELISA, PK study
 
A02061-40 Anti-Infliximab Antibody, pAb, Rabbit - ELISA, Immunogenicity assay -
 

Anti-Ipilimumab/Yervoy (Target: CTLA-4)

Cat. No. Product Name Inhibitory IC50 (μg/ml) Recommend Applications Recommended Pairs (Capture-Detection) Order
A01859-40 Anti-Ipilimumab Antibody(26B6H7D9), mAb, Mouse Non-inhibitory ELISA, PK study A01859-40 (C) - A01961-40 (D)
A01859-40 (C) - A01858-40 (D)
 
A01961-40 Anti-Ipilimumab Antibody (4H6), mAb, Mouse Non-inhibitory ELISA, PK study
 
A01858-40 Anti-Ipilimumab Antibody (4H6)[Biotin], mAb, Mouse - ELISA, PK study
 

Anti-Nivolumab/Opdivo (Target‎: ‎PD-1)

Cat. No. Product Name Inhibitory IC50 (μg/ml) Recommend Applications Recommended Pairs (Capture-Detection) Order
A01847-40 Anti-Nivolumab Antibody(8G6G3D8), mAb, Mouse Non-inhibitory ELISA, PK study A01847-40 (C) - A01965-40 (D)
A01847-40 (C) - A01848-40 (D)
 
A01965-40 Anti-Nivolumab Antibody (6G5), mAb, Mouse Non-inhibitory ELISA, PK study
 
A01848-40 Anti-Nivolumab Antibody(6G5)[Biotin], mAb, Mouse - ELISA, PK study
 
A01987-40 MonoRab™ Anti-Nivolumab Antibody (33H4), mAb, Rabbit 0.484 ELISA, PK study A01987-40 (C) - A01988-40 (D)
A01987-40 (C) - A01989-40 (D)
 
A01988-40 MonoRab™ Anti-Nivolumab Antibody (40F11), mAb, Rabbit 0.171 ELISA, PK study
 
A01989-40 MonoRab™ Anti-Nivolumab Antibody (40F11)[Biotin], mAb, Rabbit - ELISA, PK study
 
A01990-40 MonoRab™ Anti-Nivolumab Antibody (47F6), mAb, Rabbit 0.104 ELISA, PK study -
 
A01931-40 Anti-Nivolumab Antibody, pAb, Rabbit - ELISA,
Immunogenicity assay		 -
 

Anti-Obinutuzumab/Gazyva (Target: CD20)

Cat. No. Product Name Inhibitory IC50 (μg/ml) Recommend Applications Recommended Pairs (Capture-Detection) Order
A01945-40 Anti-Obinutuzumab Antibody (18H8), mAb, Mouse Non-inhibitory ELISA, PK study A01945-40 (C) - A01946-40 (D)
A01945-40 (C) - A01947-40 (D)
 
A01946-40 Anti-Obinutuzumab Antibody (16B7), mAb, Mouse Non-inhibitory ELISA, PK study
 
A01947-40 Anti-Obinutuzumab Antibody (16B7) [Biotin], mAb, Mouse - ELISA, PK study
 
A01966-40 MonoRab™ Anti-Obinutuzumab Antibody (8G12), mAb, Rabbit Non-inhibitory ELISA, PK study A01966-40 (C) - A01967-40 (D)
A01966-40 (C) - A01968-40 (D)
 
A01967-40 MonoRab™ Anti-Obinutuzumab Antibody (169F10), mAb, Rabbit Non-inhibitory ELISA, PK study
 
A01968-40 MonoRab™ Anti-Obinutuzumab Antibody (169F10) [Biotin], mAb, Rabbit - ELISA, PK study
 
A01933-40 Anti-Obinutuzumab Antibody, pAb, Rabbit - ELISA,
Immunogenicity assay		 -
 

Anti-Omalizumab/Xolair (Target: Human IgE)

Cat. No. Product Name Inhibitory IC50 (μg/ml) Recommend Applications Recommended Pairs (Capture-Detection) Order
A02095-40 Anti-Omalizumab Antibody (10G3), mAb, Mouse Non-inhibitory ELISA, PK study A02095-40 (C) - A02094-40 (D)
 
A02094-40 Anti-Omalizumab Antibody (15B12), mAb, Mouse Non-inhibitory ELISA, PK study
 
A02096-40 Anti-Omalizumab Antibody (7G11), mAb, Mouse 0.37 ELISA, PK study -
 

Anti-Palivizumab/Synagis (Target: RSV F)

Cat. No. Product Name Inhibitory IC50 (μg/ml) Recommend Applications Recommended Pairs (Capture-Detection) Order
A02112-40 Anti-Palivizumab Antibody (7B3), mAb, Mouse 0.821 ELISA, PK study A02112-40 (C) - A02111-40 (D)
 
A02111-40 Anti-Palivizumab Antibody (2F12), mAb, Mouse Non-inhibitory ELISA, PK study
 
A02064-40 Anti-Palivizumab Antibody, pAb, Rabbit - ELISA, Immunogenicity assay -
 

Anti-Panitumumab/Vectibix (Target‎: EGF Receptor)

Cat. No. Product Name Inhibitory IC50 (μg/ml) Recommend Applications Recommended Pairs (Capture-Detection) Order
A02100-40 Anti-Panitumumab Antibody (9G12), mAb, Mouse Non-inhibitory ELISA, PK study A02100-40 (C) - A02099-40 (D)
 
A02099-40 Anti-Panitumumab Antibody (2E7), mAb, Mouse 0.567 ELISA, PK study
 
A02063-40 Anti-Panitumumab Antibody, pAb, Rabbit - ELISA, Immunogenicity assay -
 

Anti-Pembrolizumab/Keytruda (Target: PD-1)

Cat. No. Product Name Inhibitory IC50 (μg/ml) Recommend Applications Recommended Pairs (Capture-Detection) Order
A01844-40 Anti-Pembrolizumab Antibody(1D6E10), mAb, Mouse Non-inhibitory ELISA, PK study -
 
A01845-40 Anti-Pembrolizumab Antibody(10E12C6)[Biotin], mAb, Mouse - ELISA, PK study -
 
A02008-40 MonoRab™ Anti-Pembrolizumab Antibody (94B9), mAb, Rabbit 0.580 ELISA, PK study A02008-40 (C) - A02007-40 (D)
 
A02007-40 MonoRab™ Anti-Pembrolizumab Antibody (47E5), mAb, Rabbit 0.009 ELISA, PK study
 
A01960-40 MonoRab™ Anti-Pembrolizumab Antibody (90G12), mAb, Rabbit  0.38 ELISA, PK study -
 
A01853-40 MonoRab™ Anti-Pembrolizumab Antibody(90G12)[Biotin], mAb, Rabbit - ELISA, PK study -
 
A01846-40 Anti-Pembrolizumab Antibody, pAb, Rabbit - ELISA,Immunogenicity assay -
 

Anti-Pembrolizumab/Keytruda PK ELISA Kit

Cat. No. Product Name Application Order
L00968 Pembrolizumab Pharmacokinetic ELISA Kit GenScript’s Pembrolizumab Pharmacokinetic ELISA Kit is designed to quantify Pembrolizumab in serum and plasma with high specificity and sensitivity. The precision, accuracy, dilution linearity, specificity, selectivity, stability and hook effect of the kit were evaluated and validated according to ICH M10 and the FDA bioanalytical method validation guidance for industry and are all acceptable. The kit can be used for the quantification of whole Pembrolizumab and its biosimilars during drug research and development, and also for the detection of single-stranded variable fragments (scFv) of Pembrolizumab.
 

Anti-Pertuzumab/Perjeta (Target: ‎HER2)

Cat. No. Product Name Inhibitory IC50 (μg/ml) Recommend Applications Recommended Pairs (Capture-Detection) Order
A02150-40 Anti-Pertuzumab Antibody (1A3), mAb, Mouse 0.387 ELISA, PK study A02150-40 (C) - A02151-40 (D)
 
A02151-40 Anti-Pertuzumab Antibody (11H4), mAb, Mouse 0.711 ELISA, PK study
 
A02220-40 Anti-Pertuzumab Antibody, pAb, Rabbit - ELISA, Immunogenicity assay -
 

Anti-Ranibizumab/Lucentis (Target: VEGF-A)

Cat. No. Product Name Inhibitory IC50 (μg/ml) Recommend Applications Recommended Pairs (Capture-Detection) Order
A02035-40 Anti-Ranibizumab Antibody (6C3), mAb, Mouse 0.848 ELISA, PK study A02035-40 (C) - A02036-40 (D)
 
A02036-40 Anti-Ranibizumab Antibody (10D12), mAb, Mouse Non-inhibitory ELISA, PK study
 
A02037-40 Anti-Ranibizumab Antibody, pAb, Rabbit - ELISA,
Immunogenicity assay		 -
 

Anti-Rituximab/Rituxan (Target‎: ‎CD20)

Cat. No. Product Name Inhibitory IC50 (μg/ml) Recommend Applications Recommended Pairs (Capture-Detection) Order
A01969-40 Anti-Rituximab Antibody (6C1), mAb, Mouse Non-inhibitory ELISA, PK study A01969-40 (C) - A01970-40 (D)
A01969-40 (C) - A01971-40 (D)
 
A01970-40 Anti-Rituximab Antibody (17B6), mAb, Mouse Non-inhibitory ELISA, PK study
 
A01971-40 Anti-Rituximab Antibody (17B6)[Biotin], mAb, Mouse - ELISA, PK study
 
A01942-40 MonoRab™ Anti-Rituximab Antibody (137C6), mAb, Rabbit Non-inhibitory ELISA, PK study A01942-40 (C) - A01943-40 (D)
A01942-40 (C) - A01944-40 (D)
 
A01943-40 MonoRab™ Anti-Rituximab Antibody (194D7), mAb, Rabbit Non-inhibitory ELISA, PK study
 
A01944-40 MonoRab™ Anti-Rituximab Antibody (194D7)[Biotin], mAb, Rabbit - ELISA, PK study
 
A01918-40 Anti-Rituximab Antibody, pAb, Rabbit - ELISA,
Immunogenicity assay		 -
 

Anti-Sarilumab/Kevzara (Target: IL-6 Receptor)

Cat. No. Product Name Inhibitory IC50 (μg/ml) Recommend Applications Recommended Pairs (Capture-Detection) Order
A02042-40 Anti-Sarilumab Antibody (26B10) , mAb, Mouse 0.062 ELISA, PK study A02042-40 (C) - A02043-40 (D)
 
A02043-40 Anti-Sarilumab Antibody (23H12) , mAb, Mouse 0.056 ELISA, PK study
 
A02044-40 Anti-Sarilumab Antibody (20F5), mAb, Mouse Non-inhibitory ELISA, PK study -
 
A02122-40 Anti-Sarilumab Antibody, pAb, Rabbit - ELISA, Immunogenicity assay -
 

Anti-Secukinumab/Cosentyx (Target: ‎IL-17A)

Cat. No. Product Name Inhibitory IC50 (μg/ml) Recommend Applications Recommended Pairs (Capture-Detection) Order
A02152-40 Anti-Secukinumab Antibody (22G7), mAb, Mouse 1.923 ELISA, PK study A02152-40 (C) - A02153-40 (D)
 
A02153-40 Anti-Secukinumab Antibody (23E11), mAb, Mouse 0.654 ELISA, PK study
 

Anti-Tocilizumab/Actemra (Target: IL-6 Receptor)

Cat. No. Product Name Inhibitory IC50 (μg/ml) Recommend Applications Recommended Pairs (Capture-Detection) Order
A01978-40 Anti-Tocilizumab Antibody (14B10), mAb, Mouse Non-inhibitory ELISA, PK study A01978-40 (C) - A01979-40 (D)
A01978-40 (C) - A01980-40 (D)
 
A01979-40 Anti-Tocilizumab Antibody (6C10), mAb, Mouse 0.656 ELISA, PK study
 
A01980-40 Anti-Tocilizumab Antibody (6C10)[Biotin], mAb, Mouse - ELISA, PK study
 
A01932-40 Anti-Tocilizumab Antibody, pAb, Rabbit - ELISA, Immunogenicity assay -
 

Anti-Trastuzumab/Herceptin (Target: HER2)

Cat. No. Product Name Inhibitory IC50 (μg/ml) Recommend Applications Recommended Pairs (Capture-Detection) Order
A02032-40 Anti-Trastuzumab Antibody (11C4), mAb, Mouse - ELISA, PK study A02032-40 (C) - A02033-40 (D)
 
A02033-40 Anti-Trastuzumab Antibody (15H2), mAb, Mouse - ELISA, PK study
 

Anti-Ustekinumab/Stelara (Target: IL-12 & ‎IL-23)

Cat. No. Product Name Inhibitory IC50 (μg/ml) Recommend Applications Recommended Pairs (Capture-Detection) Order
A02118-40 Anti-Ustekinumab Antibody (9A5), mAb, Mouse Non-inhibitory ELISA, PK study A02118-40 (C) - A02117-40 (D)
 
A02117-40 Anti-Ustekinumab Antibody (5F9), mAb, Mouse Non-inhibitory ELISA, PK study
 
A02119-40 Anti-Ustekinumab Antibody (11E3), mAb, Mouse 0.5 ELISA, PK study -
 
A02123-40 Anti-Ustekinumab Antibody, pAb, Rabbit - ELISA, Immunogenicity assay -
 

Applications

Resources

Anti-idiotype Antibodies
Anti-idiotype Antibodies

Support PK and immunogenicity study of biosimilars.

Free Download

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