Technical Resources for Gene Services

Webinars

See the full list of Upcoming and Archived Webinars, or click below to watch:

• • Codon optimization: Why & how to design DNA sequences for optimal soluble protein expression
  • Design high specificity CRISPR/Cas9 gRNAs: principles and tools
  • Gene variant libraries: design, construction, and research applications
  • Building a Synthetic Eukaryotic Genome: Design, Construction and Application

Bioinformatics Tools

• • Nucleic Acid Conversions  
  • Rare Codon Analysis Tool  
  • Codon Frequency Table
  • Genetic Code Table
  • Gene Mutagenesis Designer
• • Real-time PCR (TaqMan) Primer Design  
  • PCR Primer Design
  • Sequencing Primer Design  
  • Oligo Calculator for Tm, MV, and ug/OD

• • Sequence Manipulation Suite
  • Restriction Enzyme Map Analysis
  • Common Restriction Enzyme Sites
  • Restriction Enzyme Tool New!
• • siRNA Target Finder
  • siRNA Construct Builder
  • siRNA Sequence Scrambler

Frequently Asked Questions

• • What is Gene Synthesis and how is it performed? (pdf download)
  • Why use Gene Synthesis instead of PCR cloning?
  • Why choose sequence-verified clones instead of DNA fragments?
  • What Research Applications benefit from Gene Synthesis?
• • What is Codon Optimization?
  • What Peer-Reviewed Publications Cite GenScript's Gene Synthesis?
  • Service Selection Guide
  • How can I talk to someone about my specific project, or get a price quote?

Peer-reviewed Publications

Check out the featured papers citing each of our Gene Services below, or Search over 10,000 publications that cite GenScript Services and Products

• Gene synthesis
  • Structure of RSV fusion glycoprotein trimer bound to a prefusion-specific neutralizing antibody McLellan JS et al. Science. 2013 May.
  • Principles for designing ideal protein structures. Koga N et al. Nature. 2012 Nov.

    » more papers citing gene synthesis

• Mutagenesis/Mutant Libraries
  • A library of TAL effector nucleases spanning the human genome Kim Y et al. Nat Biotechnol. 2013 Mar
  • Control of PKA stability and signalling by the RING ligase praja2. Lignitto L et al. Nat Cell Biol. 2011 Apr

    » more papers citing Mutagenesis services

• Codon optimization
  • ReaChR: a red-shifted variant of channelrhodopsin enables deep transcranial optogenetic excitation.
    Lin JY et al. Nat Neurosci. 2013 Sep.
  • Lyn is a redox sensor that mediates leukocyte wound attraction in vivo. Yoo SK et al. Nature. 2011 Nov.

    » more papers citing codon optimization

• Cloning
  • Hepatitis-C-virus-like internal ribosome entry sites displace eIF3 to gain access to the 40S subunit.
    Hashem Y et al. Nature. 2013 Nov
  • Human Serum Protein Enhances Hiv-1 Replication And Up-Regulates The Transcription Factor Ap-1.
    Perdomo MF et al. PNAS 2012 Oct

    » more papers citing PCR cloning / custom subcloning services

• Plasmid Prep
  • Targeting of a natural killer cell receptor family by a viral immunoevasin. Berry R et al. Nat Immunol. 2013 Jul
  • KDEL Peptide Gold Nanoconstructs: A Promising Nanoplatform for Drug Delivery.
    Wang G et al. Nanomedicine. 2013 Apr

    » more papers citing Plasmid DNA Preparation services

Protocols

• • How to store and reconstitute plasmid DNA received from GenScript

Brochures to Download

• • Gene Synthesis Handbook
  • Molecular Cloning Handbook
  • Synthetic Biology
  • Optimum Gene™ codon optimization
  • GenBuilder™ Seamless Cloning
• • Gene Synthesis Services
  • Molecular Biology Services
  • Custom Bio-Reagents
  • GenScript Company Overview