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Harnessing mRNA immunization strategy for challenging GPCR protein antibody discover

Multi-transmembrane proteins, especially G-protein coupled receptors (GPCRs), are extremely difficult to develop antibodies against due to their low expression levels, insolubility in vitro, unstable purification and difficulty in maintaining their native

05-10-2024 Dr. Tingting Xiao, Antibody Senior Scientist, GenScript

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