GenRCA Rare Codon Analysis Tool provides comprehensive evaluation of codon usage preferences for coding sequence(s) of interest, supporting up to 31 codon preference indices and 65 expression host organisms. The provided analysis report could serve as an informative reference to evaluate whether a further codon optimization is required for heterologous expression.

The detailed description of codon usage bias indices can be downloaded here.

Step 1: Select expression host organism along with its reference source.
Step 2: Enter coding sequence(s) into the table.
Step 3: Click "Analysis" button to view analysis result.

* Copy & Paste your sequence(s) into the spreadsheet