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Catalog Products » Antibodies » Primary Antibodies » Immune Checkpoint Antibodies » Anti-Pembrolizumab Antibody, pAb, Rabbit

Anti-Pembrolizumab Antibody, pAb, Rabbit

Synonyms Rabbit polyclonal to Keytruda
Description Pembrolizumab (Keytruda) is a humanized monoclonal antibody that is approved by the U.S. Food and Drug Administration for the treatment of patients with unresectable or metastatic melanoma. Pembrolizumab binds to the human cell surface receptor PD-1 (Programmed Cell Death Protein 1) and blocks its interaction with PD-L1, resulting in the activation of T-cell-mediated immune responses against tumor cells.
GenScript Anti-Pembrolizumab Antibody, pAb, Rabbit is produced from sera of a rabbit immunized with Pembrolizumab.
Host Species Rabbit
Conjugation Unconjugated
Immunogen Pembrolizumab
Purification Antigen affinity column

Concentration 0.5 mg/ml, lyophilized with PBS, pH 7.4, containing 0.02% sodium azide. (It could be customized for bulk order)
Reconstitution Reconstitute the lyophilized antibody with deionized water (or equivalent) to a final concentration of 0.5 mg/ml.
Specificity The product is specific for Pembrolizumab. This antibody serves as an excellent positive control for Pembrolizumab immunogenicity (ADA) assays.
Storage The lyophilized product remains stable up to 1 year at -20°C from date of receipt. Upon reconstitution, it can be stored for 2-3 weeks at 2-8°C or for up to 12 months at -20°C or below. Avoid repeated freeze and thaw cycles.
Note GenScript can customize this product per customer's request including product size, buffer components, etc.

Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
ELISA detection: 0.01-0.1 µg/ml
Other applications: user-optimize


Cat. No.
Product Name
Price
A01845-40
Anti-Pembrolizumab Antibody(10E12C6)[Biotin], mAb, Mouse - 40 ug
$99.00
A01844-40
Anti-Pembrolizumab Antibody(1D6E10), mAb, Mouse - 40 ug
$99.00
 



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Cat. No. A01846
Size
Price
40 ug $198.00