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Home » Gene Synthesis & Molecular Biology Services » Anti-Tocilizumab Antibody, pAb, Rabbit

Anti-Tocilizumab Antibody, pAb, Rabbit

Description Tocilizumab (Actemra) is a humanized monoclonal antibody that is developed by Hoffmann–La Roche and Chugai for the treatment of patients with rheumatoid arthritis (RA) and systemic juvenile idiopathic arthritis, a severe form of arthritis in children. Tocilizumab binds to the interleukin-6 receptor (IL-6R) and blocks its interaction with interleukin 6 (IL-6), hindering IL-6 from exerting its pro-inflammatory effects.
Host Species Rabbit
Conjugation Unconjugated
Immunogen Tocilizumab
Purification Antigen affinity column

Concentration 0.5 mg/ml, lyophilized with PBS, pH 7.4, contains 0.02% sodium azide. (Might be eligible for customized bulk orders.)
Reconstitution Reconstitute the lyophilized antibody with deionized water (or equivalent) to a final concentration of 0.5 mg/ml.
Specificity The product is specific for Tocilizumab. This antibody serves as an excellent positive control for Tocilizumab immunogenicity (ADA) assays.
Storage The lyophilized product remains stable up to 1 year at -20 °C from date of receipt. Upon reconstitution, it can be stored for 2-3 weeks at 2-8 °C or for up to 12 months at -20 °C or below. Avoid freeze/thaw cycles.
Note GenScript can customize this product per customer's request including product size, buffer components, etc.

Working concentrations for specific applications should be determined by the investigators. The appropriate concentration may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.

ELISA detection: 0.005-1 µg/ml
Other applications: user-optimize

  • Anti-Tocilizumab Antibody, PAb, Rabbit
  • Anti-Tocilizumab Antibody, PAb, Rabbit

    ELISA binding of Anti-Tocilizumab Antibody, pAb, Rabbit (GenScript, A01932-40) with Tocilizumab.
    Coating antigen: Tocilizumab, 1 µg/ml.
    Anti-Tocilizumab Antibody, pAb, Rabbit (GenScript, A01932-40) dilution start from 1,000 ng/ml, EC₅₀= 2.247 ng/ml.


Cat. No.
Product Name
Price
A01978-40
Anti-Tocilizumab Antibody (14B10), mAb, Mouse - 40 µg
$99.00
A01979-40
Anti-Tocilizumab Antibody (6C10), mAb, Mouse - 40 µg
$99.00
A01980-40
Anti-Tocilizumab Antibody (6C10)[Biotin], mAb, Mouse - 40 µg
$99.00
 


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Cat. No. A01932
Size
Price
40 µg $198.00