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MonoRabTM Anti-Pembrolizumab Antibody (90G12), mAb, Rabbit
MonoRab™ Anti-Pembrolizumab Antibody (90G12), mAb, Rabbit
MonoRab™ Anti-Pembrolizumab antibody (90G12) (GenScript, A01960-40) binds with Pembrolizumab. While the antibody does not recognize the human IgG Fc fragment (data not shown).
Coating antigen: Pembrolizumab, 1 μg/ml.
Anti-Pembrolizumab antibody dilution start from 1,000 ng/ml.
MonoRab™ Anti-Pembrolizumab antibody (90G12) (GenScript, A01960-40) blocks Pembrolizumab binding with Human PD-1 recombinant protein (Z03370, PD-1-Fc Chimera, Human).
Coating antigen: Pembrolizumab, 1 μg/ml.
PD-1-Fc-biotin final concentration: 20 ng/ml.
Anti-Pembrolizumab antibody dilution start from 10 μg/ml.
| Synonyms | Rabbit monoclonal to Keytruda |
| Description | Pembrolizumab (Keytruda) is a humanized monoclonal antibody that is
approved by the U.S. Food and Drug Administration for the treatment of patients
with unresectable or metastatic melanoma. Pembrolizumab binds to the human cell
surface receptor PD-1 (Programmed Cell Death Protein 1) and blocks its
interaction with PD-L1, resulting in the activation of T-cell-mediated immune
responses against tumor cells. GenScript MonoRabTM Anti-Pembrolizumab Antibody (90G12), mAb, Rabbit is produced from a hybridoma resulting from the fusion of partner and B-lymphocytes obtained from a rabbit immunized with Pembrolizumab. |
| Host Species | Rabbit |
| Conjugation | Unconjugated |
| Immunogen | Pembrolizumab |
| Purification | Protein A affinity column |
| Subclass | IgG |
| Clone ID | 90G12 |
| Concentration | 0.5 mg/ml, lyophilized
with PBS, pH 7.4, containing 0.02% sodium azide. |
| Reconstitution | Reconstitute the
lyophilized antibody with deionized water (or equivalent) to a final
concentration of 0.5 mg/ml. |
| Specificity | The product is specific for Pembrolizumab. This antibody blocks
Pembrolizumab binding with human PD-1 recombinant
protein (Z03370, PD‑1 Fc Chimera, Human) in ELISAs. |
| Storage | The lyophilized product remains stable up to 1 year at -20 °C from date of receipt. Upon reconstitution, it can be stored for 2-3 weeks at 2-8 °C or for up to 12 months at -20 °C or below. Avoid repeated freezing and thawing cycles. |
| Note | GenScript can customize this product per customer's request including product size, buffer components, etc. |
| Working
concentrations for specific applications should be determined by the
investigators. The appropriate concentrations may be affected
by secondary antibody affinity, antigen concentration, the sensitivity of the
method of detection, temperature, the length of the incubations, and other
factors. The suitability of this antibody for applications other than those
listed below has not been determined. The following concentration ranges are
recommended starting points for this product. ELISA detection: 0.01-0.1 µg/ml ELISA blocking: 10-50 µg/ml Other applications: user-optimized |
MonoRab™ Anti-Pembrolizumab antibody (90G12) (GenScript, A01960-40) binds with Pembrolizumab. While the antibody does not recognize the human IgG Fc fragment (data not shown).
Coating antigen: Pembrolizumab, 1 μg/ml.
Anti-Pembrolizumab antibody dilution start from 1,000 ng/ml.
MonoRab™ Anti-Pembrolizumab antibody (90G12) (GenScript, A01960-40) blocks Pembrolizumab binding with Human PD-1 recombinant protein (Z03370, PD-1-Fc Chimera, Human).
Coating antigen: Pembrolizumab, 1 μg/ml.
PD-1-Fc-biotin final concentration: 20 ng/ml.
Anti-Pembrolizumab antibody dilution start from 10 μg/ml.
For more documents, please visit "Technical Support".
| Cat. No. A01960 | ||
|---|---|---|
| Size | Price | |
| 40 µg | $198.00 | |
