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Home » Gene Synthesis & Molecular Biology Services » Anti-Tocilizumab Antibody (14B10), mAb, Mouse

Anti-Tocilizumab Antibody (14B10), mAb, Mouse

Anti-Tocilizumab Antibody (14B10), MAb, Mouse

ELISA binding of Anti-Tocilizumab Antibody (14B10) (GenScript, A01978-40) with Tocilizumab. While the antibody does not recognize the human IgG (data not shown).Coating antigen: Tocilizumab, 1 µg/ml.
Anti-Tocilizumab Antibody (14B10) (GenScript, A01978-40) dilutions start from 1,000 ng/ml.
EC₅₀=1.653 ng/ml.

Anti-Tocilizumab Antibody (14B10), MAb, Mouse

Standard curve of Tocilizumab Sandwich ELISA. The Tocilizumab Sandwich ELISA assay is developed by using Anti-Tocilizumab Antibody (14B10), mAb, Mouse (GenScript, A01978-40) and Anti-Tocilizumab Antibody (6C10), mAb, Mouse (GenScript, A01979-40) as the capture and detection antibodies, respectively
In this ELISA assay, Anti-Tocilizumab Antibody (6C10), mAb, Mouse (GenScript, A01979-40) was labeled with Biotin. GenScript can provide customized conjugation services for this product per customer's request.
The sensitivity is less than 100 pg/ml.

Synonyms Mouse monoclonal to Actemra
Description Tocilizumab also known as atlizumab, is a humanized monoclonal antibody that is approved by the U.S. Food and Drug Administration. It has a high affinity to IL-6R and blocks the IL-6 signaling by preventing the formation of the IL-6/IL-6R complex. Tocilizumab is used for the treatment of rheumatoid arthritis (RA) and systemic juvenile idiopathic arthritis, a severe form of arthritis in children.
Anti-Tocilizumab Antibody (14B10), mAb, Mouse is produced from a hybridoma resulting from the fusion of partner and B-lymphocytes obtained from a mouse immunized with Tocilizumab.
Host Species Mouse
Conjugation Unconjugated
Immunogen Tocilizumab
Purification Protein A affinity column

Subclass IgG2b
Clone ID 14B10
Concentration 0.5 mg/ml, lyophilized with PBS, pH 7.4, containing 0.02% sodium azide.
Reconstitution Reconstitute the lyophilized antibody with deionized water (or equivalent) to a final concentration of 0.5 mg/ml.
Specificity The product is specific for Tocilizumab. The antibody is recommended as a capture antibody in a pharmacokinetic (PK) bridging assay with detection antibody GenScript, A01979-40, Anti-Tocilizumab Antibody (6C10), mAb, Mouse.
Storage The lyophilized product remains stable up to 1 year at -20 °C from date of receipt. Upon reconstitution, it can be stored for 2-3 weeks at 2-8 °C or for up to 12 months at -20 °C or below. Avoid freeze/thaw cycles.
Note GenScript can customize this product per customer's request including product size, buffer components, etc.

Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.

ELISA detection: 0.01-0.1 µg/ml
Other applications: user-optimized

  • Anti-Tocilizumab Antibody (14B10), MAb, Mouse
  • Anti-Tocilizumab Antibody (14B10), MAb, Mouse

    ELISA binding of Anti-Tocilizumab Antibody (14B10) (GenScript, A01978-40) with Tocilizumab. While the antibody does not recognize the human IgG (data not shown).Coating antigen: Tocilizumab, 1 µg/ml.
    Anti-Tocilizumab Antibody (14B10) (GenScript, A01978-40) dilutions start from 1,000 ng/ml.
    EC₅₀=1.653 ng/ml.

  • Anti-Tocilizumab Antibody (14B10), MAb, Mouse
  • Anti-Tocilizumab Antibody (14B10), MAb, Mouse

    Standard curve of Tocilizumab Sandwich ELISA. The Tocilizumab Sandwich ELISA assay is developed by using Anti-Tocilizumab Antibody (14B10), mAb, Mouse (GenScript, A01978-40) and Anti-Tocilizumab Antibody (6C10), mAb, Mouse (GenScript, A01979-40) as the capture and detection antibodies, respectively
    In this ELISA assay, Anti-Tocilizumab Antibody (6C10), mAb, Mouse (GenScript, A01979-40) was labeled with Biotin. GenScript can provide customized conjugation services for this product per customer's request.
    The sensitivity is less than 100 pg/ml.


Cat. No.
Product Name
Price
A01979-40
Anti-Tocilizumab Antibody (6C10), mAb, Mouse - 40 µg
$99.00
A01980-40
Anti-Tocilizumab Antibody (6C10)[Biotin], mAb, Mouse - 40 µg
$99.00
A01932-40
Anti-Tocilizumab Antibody, pAb, Rabbit - 40 µg
$198.00
 



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Cat. No. A01978
Size
Price
40 µg $99.00