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Home » Gene Synthesis & Molecular Biology Services » MonoRabᵀᴹ Anti-Daratumumab Antibody (139B10), mAb, Rabbit

MonoRabᵀᴹ Anti-Daratumumab Antibody (139B10), mAb, Rabbit

MonoRabᵀᴹ Anti-Daratumumab Antibody (139B10), MAb, Rabbit

MonoRabTM Anti-Daratumumab Antibody (139B10), mAb, Rabbit (GenScript, A02009-40) blocks Daratumumab binding with Human CD38 protein.
Coating antigen: CD38 protein, 1 µg/ml
Daratumumab-biotin final concentration: 10 ng/ml
MonoRabTM Anti-Daratumumab Antibody (139B10), mAb, Rabbit (GenScript, A02009-40) dilutions start from 10 μg/ml
IC₅₀= 17.11 ng/ml

MonoRabᵀᴹ Anti-Daratumumab Antibody (139B10), MAb, Rabbit

ELISA binding of MonoRabTM Anti-Daratumumab Antibody (139B10) (GenScript, A02009-40) with Daratumumab. While the antibody does not recognize the human IgG Fc fragment (data not shown).
Coating antigen: Daratumumab, 1 µg/ml.
MonoRabTM Anti-Daratumumab Antibody (139B10) (GenScript, A02009-40) dilutions start from 1,000 ng/ml.
EC₅₀= 3.092 ng/ml.

Description Daratumumab (Darzalex) is a human IgG1k monoclonal antibody that is approved by the U.S. Food and Drug Administration for the treatment of multiple myeloma. It binds with high affinity to CD38, which is highly expressed on the surface of multiple myeloma cells. Daratumumab can make immune system to attack cancer cells, resulting in rapid tumor cell death through immunomodulatory effects.
GenScript MonoRabTM Anti-Daratumumab Antibody (139B10), mAb, Rabbit is produced from a hybridoma resulting from the fusion of partner and B-lymphocytes obtained from a rabbit immunized with Daratumumab.
Host Species Rabbit
Conjugation Unconjugated
Immunogen Daratumumab
Purification Protein A affinity column

Subclass IgG
Clone ID 139B10
Concentration 0.5 mg/ml, lyophilized with PBS, pH 7.4, containing 0.02% sodium azide.
Reconstitution Reconstitute the lyophilized antibody with deionized water (or equivalent) to a final concentration of 0.5 mg/ml.
Specificity The product is specific for Daratumumab.
Storage The lyophilized product remains stable up to 1 year at -20 °C from date of receipt. Upon reconstitution, it can be stored for 2-3 weeks at 2-8 °C or for up to 12 months at -20 °C or below. Avoid repeated freezing and thawing cycles.
Note GenScript can customize this product per customer's request including product size, buffer components, etc.

Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
ELISA detection: 0.01-0.1 µg/ml
ELISA blocking: 1-10 µg/ml
Other applications: user-optimized

  • MonoRabᵀᴹ Anti-Daratumumab Antibody (139B10), MAb, Rabbit
  • MonoRabᵀᴹ Anti-Daratumumab Antibody (139B10), MAb, Rabbit

    MonoRabTM Anti-Daratumumab Antibody (139B10), mAb, Rabbit (GenScript, A02009-40) blocks Daratumumab binding with Human CD38 protein.
    Coating antigen: CD38 protein, 1 µg/ml
    Daratumumab-biotin final concentration: 10 ng/ml
    MonoRabTM Anti-Daratumumab Antibody (139B10), mAb, Rabbit (GenScript, A02009-40) dilutions start from 10 μg/ml
    IC₅₀= 17.11 ng/ml

  • MonoRabᵀᴹ Anti-Daratumumab Antibody (139B10), MAb, Rabbit
  • MonoRabᵀᴹ Anti-Daratumumab Antibody (139B10), MAb, Rabbit

    ELISA binding of MonoRabTM Anti-Daratumumab Antibody (139B10) (GenScript, A02009-40) with Daratumumab. While the antibody does not recognize the human IgG Fc fragment (data not shown).
    Coating antigen: Daratumumab, 1 µg/ml.
    MonoRabTM Anti-Daratumumab Antibody (139B10) (GenScript, A02009-40) dilutions start from 1,000 ng/ml.
    EC₅₀= 3.092 ng/ml.




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Cat. No. A02009
Size
Price
40 µg $198.00