Rabbit Anti-Mouse IgM (H&L),pAb

*This product has been discontinued!*

Immunoglobulin M is the largest antibody isotype and the first to be secreted against an initial exposure to antigen. IgM is predominantly produced in the spleen. Formed from covalently linking 5 immunoglobulins together, the approximate molecular weight of IgM is 900kDa and possesses 10 binding sites (though due to the size of most antigens, not all sites are capable of binding at once). Due to this large size, IgM is typically isolated to the serum.

Cat. No.	A10002
Size	Buy in bulk

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Overview Properties Background

Overview

Specificity	This product was prepared from monospecific antiserum by a delipidation and defibrination. Assay by immunoelectrophoresis resulted in predominantly a single precipitin arc against Mouse IgM and Mouse Serum. No reaction was observed against Mouse IgG F(c). Some light chain cross reactivity may occur against Mouse IgG.
Host Species	Rabbit
Immunogen	Mouse IgM whole molecule

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Properties

Concentration	Lyophilized , 0.01 M Sodium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Reconstitution	Restore with deionized water (or equivalent)

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Background

Target Background

Rabbit Anti-Mouse IgM (H&L) antibody Unconjugated, pAb. Immunoglobulin M is the largest antibody isotype and the first to be secreted against an initial exposure to antigen. IgM is predominantly produced in the spleen. Formed from covalently linking 5 immunoglobulins together, the approximate molecular weight of IgM is 900kDa and possesses 10 binding sites (though due to the size of most antigens, not all sites are capable of binding at once). Due to this large size, IgM is typically isolated to the serum.

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