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D-dimer (18D4), mAb, Mouse

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Overview

Synonyms	D-dimer Antibody (18D4), mAb, Mouse
Description	D-dimer known as a fibrin degradation product, is presented in blood after a blood clot is degraded by fibrinolysis. Its concentration in blood increases when deep venous thrombosis (DVT), pulmonary embolism (PE) or disseminated intravascular coagulation (DIC) happens. It serves as a useful maker for the diagnosis of these diseases.
Antigen Species	Human
Conjugation	unconjugated
Purification	Protein A/G affinity column

Properties

Production	Cultured in vitro under conditions free from animal-derived components
Clone ID	18D4
Subclass	IgG2a
Concentration	>4mg/ml
Recommended pairs	Sandwich immunoassay (Capture-Detection): 15C18 - 16D25 15C18 - 18D4
Formulation	PBS, pH 7.4, containing 0.03% Proclin 300
Storage	For long term storage, aliquot and store at -20°C or below. Avoid repeated freezing and thawing cycles.
Note	GenScript can customize this product per customer's request including product size, buffer components,etc.

GenScript's mAb combination 16D25-18D4 (Capture-Detection) shows good correlation with Siemens D-dimer assays. D-dimer concentration was measured in 38 human blood samples using sandwich ELISA.We compared our 16D25-18D4 assay to Siemens D-dimer assay, the results of the measurements showed good correlation (R²=0.95).