Figure 6: The test results show that Benz-Neburase can also remove
DNA and plasmid residue in AAV virus production process more effectively than the competitor product.
Viral genome (Vg) recovery was used to quantify the adeno associated viral production. The analysis data
indicate that the use of Benz-Neburase has minimal impact on the viral production. The data further
indicates that the GenScript Benz-Neburase outperforms the competitor product, while the Benz-Neburase GMP
has comparative performance.
Expression system: HEK293
Virus type: AAV
Process flow: adding nuclease to virus supernatant
Purpose: Remove sample plasmid residue and host DNA residue
Dosage: 50 units/mL
Reaction time: 1 h