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gamma ()-globulin

Gamma globulin or immunoglobulin (Ig) refers to proteins present in the blood plasma. Blood serum gel electrophoresis separates proteins into five distinct bands corresponding to Albumin, alpha 1-globulin, alpha 2-globulin, beta-globulin, and gamma-globulin. The gamma globulin fraction is rich in antibodies. Antibodies are classified into five different isotypes (i.e., IgM, IgD, IgG, IgA, and IgE) based on their heavy chain composition. IgG is the most abundant antibody isotype in the blood plasma.

Gamma globulins may be administered parenterally as a therapeutic option. Intravenous gamma globulin (IVIG) boosts immunity and is a treatment option in cases of immunodeficiencies to help prevent infections.


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