It is a desirable feature for a candidate antibody and refers to the ability of the antibody to bind and functionally interact with the orthologous proteins from various animal species used as models for evaluation of in vivo efficacy, pharmacokinetic and pharmacodynamic (PK/PD), and safety. The animals routinely used for these purposes include but are not limited to mouse, rat, rabbit, and cynomolgus monkeys.
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GenSmart Optimization is a free online tool for performing codon optimization to improve gene expression. GenScript's patented algorithms are integrated into the tool to optimize the computing capability of high-performance sequence generation.
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GenSmart™ Design is a free online DNA construct design tool developed by GenScript. GenSmart™ Design has two design modules, the Create Construct module for individual plasmid design and the Create Library module for DNA library design.
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If you know of any terms that have been omitted from this glossary that you feel would be useful to include, please send detail to the Editorial Office at GenScript: [email protected]