Resources

List by Alphabet: A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

polyclonal antibody

A polyclonal antibody refers to a mixture of antibodies that are generated by different B cells (immune cells) in response to a specific antigen. These antibodies recognize various epitopes (distinct regions) on the antigen, resulting in a diverse range of antibodies with varying binding specificities.

Polyclonal antibodies are naturally produced by the immune system in response to infections, vaccinations, or exposure to foreign substances. When the immune system encounters an antigen, multiple B cells are activated, each producing a slightly different antibody that can bind to different parts of the antigen.

Key characteristics of polyclonal antibodies include:

1. Diversity: Polyclonal antibodies recognize multiple epitopes on the target antigen, increasing the likelihood of successful binding and detection.

2. Broad Specificity: Due to their diverse origins, polyclonal antibodies are more likely to detect a variety of related molecules or antigen variants.

3. Complex Composition: Polyclonal antibody preparations consist of a mixture of antibodies, each produced by a different B cell clone. This complexity can be advantageous for certain applications but may also introduce variability.

Polyclonal antibodies have been widely used in various scientific and medical applications, including:

• Diagnostic Tests: Polyclonal antibodies are used in diagnostic tests, such as enzyme-linked immunosorbent assays (ELISAs) and immunohistochemistry, to detect the presence of specific antigens in samples.
• Research: Polyclonal antibodies are used in research to study the localization and expression of proteins within cells and tissues.
• Therapeutics: In some cases, polyclonal antibody preparations can be used as therapeutics, particularly in the treatment of certain infectious diseases or venomous bites.

Related Service
• Genscript offers Custom Polyclonal Antibody Production Services and Standard Polyclonal Antibody Services.
• Related tool: GenSmart™ Variable Domain Sequence Analyzer

Related Biology Tools

  • GenSmart™ Codon Optimization

    GenSmart Optimization is a free online tool for performing codon optimization to improve gene expression. GenScript's patented algorithms are integrated into the tool to optimize the computing capability of high-performance sequence generation.

    Learn More

  • DNA Construct Design Tool

    GenSmart™ Design is a free online DNA construct design tool developed by GenScript. GenSmart™ Design has two design modules, the Create Construct module for individual plasmid design and the Create Library module for DNA library design.

    Learn More

  • Codon Frequency Tables

    This online tool shows commonly used genetic codon frequency table in expression host organisms including Escherichia coli and other common host organisms.

    Learn More

Service and Products

Antibody Production Services

Comprehensive custom antibody production services including monoclonal and polyclonal antibody production services with industry leading turnaround times.

Polyclonal Antibody Services

The fastest custom polyclonal antibody production services in the industry with unmatched guarantees.

Custom Monoclonal Antibody Development Services

Developing custom monoclonal antibodies with standard or fully custom protocols including everything from antigen synthesis to antibody scale-up options.

Phospho-Specific Antibody Services

Guaranteed ELISA titer of ≥ 1:64,000 and < 10% cross reactivity with non-phospho peptide.

Immunoassay Development Services

Our custom immunoassay development service offering comprehensive high-throughput assay development with fast turnaround and high efficiency.

Large-scale Antibody Manufacturing

Our large-scale antibody manufacturing services offer polyclonal and monoclonal antibody production of gram quantities for industrial antibody yields.

COVID-19 Reagent Antibodies

On demand SARS-CoV-2 control mAbs ideal for diagnostics, therapeutic, and vaccine development.

If you know of any terms that have been omitted from this glossary that you feel would be useful to include, please send detail to the Editorial Office at GenScript: [email protected]

If your term is adopted, we will send 1,000 EzCoupon points to your GenScript account.