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mAb stands for monoclonal antibody. Monoclonal antibodies are laboratory-produced molecules that are designed to mimic the immune system's ability to fight off harmful pathogens such as viruses and bacteria. They are made by cloning a single type of immune cell, called a B cell, that produces a specific antibody against a particular antigen. This produces a large number of identical antibodies that can be used for various applications in medicine and research.

mAbs have become an important tool in the treatment of various diseases, including cancer, autoimmune disorders, and infectious diseases. They can be used to target specific cells or molecules in the body, such as cancer cells or viral proteins, and trigger an immune response to destroy them. They can also be used for diagnostic purposes, such as detecting the presence of specific proteins or cells in a patient's blood.

mAbs are typically produced using recombinant DNA technology and can be engineered to have specific properties, such as increased potency or longer half-life in the body. They are administered through injection or infusion and have relatively few side effects compared to traditional chemotherapy drugs.

In summary, mAb stands for monoclonal antibody and refers to laboratory-produced molecules that mimic the immune system's ability to fight off harmful pathogens. They have become an important tool in the treatment of various diseases and can be engineered for specific properties.

Learn more about antibody drug discovery glossary:

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If you know of any terms that have been omitted from this glossary that you feel would be useful to include, please send detail to the Editorial Office at GenScript: [email protected]

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