×
Catalog Products » Other Products » Stable Cell Lines
Email to GenScript
Stable Cell Lines

Immune Checkpoint Stable Cell Lines

Inhibitors of immune-checkpoint proteins, such as PD1, PD-L1, VISTA, Tim3 and Lag3, have indicated broad and diverse opportunities to increase antitumor immunity by enhancing T cell activity with the potential to produce durable clinical responses. To meet these needs, we have developed stable cell line products expressing the most popular immune checkpoints to accelerate your immunotherapy drug discovery and achieve US Food and Drug Administration (FDA) approval. All these stable cells are developed for screening high affinity antibodies against immune checkpoint proteins.

Key features

Product Overview: Immune Checkpoint Stable Cell Lines


Receptor Cell Line Cat.No.
4-1BB CHO-K1/4-1BB
CHO-K1/mouse 4-1BB
CHO-K1/cyno 4-1BB
B7-H2 CHO-K1/B7-H2
B7-H3 CHO-K1/B7-H3
B7-H4 CHO-K1/B7-H4
BDCA2 CHO-K1/BDCA2
CHO-K1/Cyno BDCA2
CHO-K1/BDCA2 and FcER1G
CHO-K1/ Cyno BDCA2 and FcER1G
BTLA CHO-K1/BTLA
CD155 CHO-K1/CD155
CHO-K1/Cyno CD155
CHO-K1/Mouse CD155
CD160 CHO-K1/CD160
CD200 R1 CHO-K1/CD200 R1
CD27 CHO-K1/CD27
CD38 CHO-K1/CD38
CHO-K1/mouse CD38 M00636
CD40 CHO-K1/CD40
CD47 CHO-K1/CD47
CHO-K1/Mouse CD47 M00631
CHO-K1/Cyno CD47 M00632
CD80 CHO-K1/CD80
CD86 CHO-K1/CD86
CD64 CHO-K1/CD112
CTLA4 CHO-K1/CTLA4
CHO-K1/mouse CTLA4
CHO-K1/cyno CTLA4
FLT3 CHO-K1/FLT3
CHO-K1/mouse FLT3
CHO-K1/cyno FLT3
GITR CHO-K1/GITR
HVEM CHO-K1/HVEM
CHO-K1/mouse HVEM M00647
ICOS CHO-K1/ICOS M00649
KIR CHO-K1/KIR M00650
Lag3 CHO-K1/Lag3
OX-40 CHO-K1/OX-40
CHO-K1/OX-40L
PD-1 CHO-K1/PD-1
CHO-K1/mouse PD-1
CHO-K1/cyno PD-1
Daudi/PD-1 M00630
PD-L1 CHO-K1/PD-L1
HEK293/PD-L1
CHO-K1/mouse PD-L1
CHO-K1/cyno PD-L1
PD-L2 CHO-K1/PD-L2
CHO-K1/mouse PD-L2 M00628
CHO-K1/cyno PD-L2 M00629
SIRP CHO-K1/SIRP alpha
CHO-K1/SIRP gamma
VISTA CHO-K1/VISTA
CHO-K1/Mouse VISTA M00633
CHO-K1/Cyno VISTA M00634
TIGIT CHO-K1/TIGIT
CHO-K1/Cyno TIGIT
CHO-K1 /mouse TIGIT
Tim3 CHO-K1/Tim3

Back to the top


Fc Receptor Cell Lines

Product Overview: Fc Receptor Cell Lines

Receptor Cell Line Cat.No.
CD16 CHO-K1/CD16A 158F
CHO-K1/CD16B
CD32A CHO-K1/CD32A 131His
CHO-K1/CD32A 131Arg
CD32B CHO-K1/CD32B 232Ile
CHO-K1/CD32B 232Thr
CD32C CHO-K1/CD32C 13Gln
CD64 CHO-K1/CD64
FcRn CHO-K1/FcRn

GPCR & Ion Channel Stable Cell Lines

GenScript offers a wide selection of GPCR & ion channel stable cell lines. Proprietary codon optimization and vector design technologies enable GenScript to overcome low functional protein expression at the cell surface. All of the cell lines have been optimized for S/B ratio in calcium flux assays, FRET assays, or chemiluminescent assays. They are shown to be stable for 16 passages.

Key features


Product Overview: GPCR & Ion Channel Stable Cell Lines


Family
Receptor
Cell Line
Cat.No.
5-Hydroxytryptamine receptor 5-HT1A/HTR1A CHO-K1/5-HT1A/Gα15
5-HT2A/HTR2A CHO-K1/5-HT2A
5-HT2B/HTR2B CHO-K1/5-HT2B
5-HT2C/HTR2C CHO-K1/5-HT2C
5-HT2C/HTR2C HEK 293/5-HT2C
HTR4 CHO-K1/5-HT4/Gα15
HTR7 293/5-HT7/CRE-Luc
Acetylcholine receptor (muscarinic) M1/CHRM1 CHO-K1/M1
M2/CHRM2 CHO-K1/M2/Gα15
M3/CHRM3 CHO-K1/M3
M4/CHRM4 CHO-K1/M4/Gα15
M5/CHRM5 CHO-K1/M5
Adenosine receptor ADORA1 CHO-K1/ADORA1/Gα15
ADORA1 293/ADORA1/Gα15
ADORA2a CHO-K1/ADORA2A/Gα15
ADORA2a CHO-K1/mouse ADORA2A
ADORA2B CHO-K1/ADORA2B/Gα15
ADORA3 CHO-K1/ADORA3/Gα15
Adrenoceptors ADRB3 293/ADRB3/CRE-Luc
ADRA1B CHO-K1/ADRA1B
ADRA1D CHO-K1/ADRA1D
ADRA2A CHO-K1/ADRA2A/Gα15
ADRA2B CHO-K1/ADRA2B/Gqi5
ADRA2C CHO-K1/ADRA2C/Gα15
ADRB1 CHO-K1/ADRB1/Gα15
ADRA1A CHO-K1/ADRA1A
Angiotensin receptor AT1 HEK 293/AT1
AT1 293T/AT1
Apelin receptor AGTRL1 CHO-K1/AGTRL1/Gα15
Bile acid receptor GPBAR1 CHO-K1/GPBAR1

Back to the top


Family
Receptor
Cell Line
Cat.No.
Bombesin receptor BB1 CHO-K1/BB1
BB2/GRPR CHO-K1/BB2
BB3/BRS3 CHO-K1/BB3
Bradykinin receptor B2 CHO-K1/B2/Gα15
Calcitonin AMY1 CHO-K1/Gα15/AMY1  New
Calcitonin AMY2 CHO-K1/Gα15/AMY2  New
Calcitonin AMY3 CHO-K1/Gα15/AMY3   New
Calcitonin receptor CALCR/CT CHO-K1/CT/Gα15
Calcium-sensing receptor CASR CHO-K1/CASR
Cannabinoid receptor CNR1/CB1 CHO-K1/CB1/Gα15
CB2 CHO-K1/CB2
Chemerin receptor CMKLR1 CHO-K1/CMKLR1/Gα15
Chemokine receptor CCR1 CHO-K1/CCR1/Gα15   New
CCR5 CHO-K1/CCR5/Gα15   New
CXCR1/IL8RA CHO-K1/CXCR1/Gα15   New
CXCR3 CHO-K1/CXCR3/Gα15   New
CXCR4 CHO-K1/CXCR4/Gα15   New
CXCR5/BLR1 CHO-K1/CXCR5/Gα15   New
Cholecystokinin receptor CCKA/CCKAR CHO-K1/CCKA/Gα15
CCKB/CCKBR CHO-K1/CCKB
Class A orphan GPR68/OGR1 CHO-K1/GPR68/Gα15
MRGPRX2 CHO-K1/MRGPRX2
Complement peptide receptor C5a/C5AR1 CHO-K1/C5a/Gα15
Corticotropin releasing factor receptor CRF1/CRHR1 CHO-K1/CRF1/Gα15
CRF2 CHO-K1/CRF2/Gα15
Dopamine receptor D2 CHO-K1/D2/Gα15
D5 CHO-K1/D5/Gα15
D1/DRD1 CHO-K1/D1
D2(Short) CHO-K1/D2s/Gα15
Endothelin receptor ETA/EDNRA CHO-K1/EDNRA
ETB/EDNRB CHO-K1/EDNRB
Formylpeptide receptor FPR1 CHO-K1/FPR1/Gα15
Free fatty acid receptor FFA2 CHO-K1/FFA2/Gα15
GPR40/FFA1 CHO-K1/FFA1/Gα15

Back to the top


Family
Receptor
Cell Line
Cat.No.
Galanin receptor GAL1/GALR1 CHO-K1/GAL1/Gα15
GAL2/GALR2 CHO-K1/GAL2
Glucagon receptor GHRHR 293/GHRH/Gα15
GLP-1/GLP1R CHO-K1/GLP1/Gα15
GLP-1/GLP1R HEK293/CRE-Luc/GLP1R
GLP-2/GLP2R CHO-K1/GLP2/Gα15
GCGR CHO-K1/GCGR/Gα15
GCGR HEK 293/GCGR/Gα15
SCTR CHO-K1/SCTR/Gα15
GIPR CHO-K1/GIP/Gα15
Gonadotropin releasing hormone receptor GNRHR CHO-K1/GNRHR/Gα15
Growth hormone releaseing peptides receptor GHSR CHO-K1/GHSR
Histamine receptor H1/HRH1 293/H1
H2/HRH2 CHO-K1/H2/Gα15
H3/HRH3 CHO-K1/H3/Gα15
H4/HRH4 CHO-K1/H4/Gα15
Hydroxycarboxlic acid receptor GPR109A CHO-K1/NIACR1/Gα15
Kisspeptin receptor KiSS1/GPR54 CHO-K1/KiSS1
Leukotriene receptor FPRL1 CHO-K1/FPRL1/Gα15
CysLT1 CHO-K1/CysLT1/Gα15
LTB4R CHO-K1/LTB4/Gα15
Lysophospholipid receptor EDG4/LAP2 RH7777/EDG4
Melanin concentrating hormone receptor MCH1/GPR24 293/MCH1
MCH2/GPR145 CHO-K1/MCH2
Melanocortin receptor MC2 CHO-K1/MC2/Gα15
MC3 CHO-K1/MC3/Gα15
MC3 293/MC3/CRE-Luc
MC4 CHO-K1/MC4/Gα15
MC5 CHO-K1/MC5/Gα15
Melatonin receptor MTNR1A CHO-K1/MT1/Gα15
MT2/MTNR1B CHO-K1/MT2/Gα15
Metabropic glutamate receptor mGlu2/GRM2 CHO-K1/GRM2/Gα15
Motilin receptor MTLR/MLNR CHO-K1/MTLR/Gα15

Back to the top


Family
Receptor
Cell Line
Cat.No.
Neuromedin receptor NMU2 293T/NMU2
NMU1/GPR66 CHO-K1/NMU1
Neuropeptide S receptor NPS1b CHO-K1/NPS1b/Gα15
NPSR1 CHO-K1/NPS1a/Gα15
Neuropeptide Y receptor NPY2 CHO-K1/NPY2/Gqi5
NPY4R CHO-K1/NPY4/Gα15
Neurotensin receptor NTS1/NT1 CHO-K1/NTS1
Opioid & opioid-like receptor OPRD1 CHO-K1/OPRD1/Gα15
OPRK1 CHO-K1/OPRK1/Gα15
OPRM1 CHO-K1/OPRM1/Gα15
OPRL1 CHO-K1/OPRL1/Gα15
Orexin receptor OX1 CHO-K1/OX1
OX2 CHO-K1/OX2
P2Y receptor P2Y1 1321N1/P2Y1
P2Y2 1321N1/P2Y2
P2Y4 1321N1/P2Y4
P2Y6 1321N1/P2Y6
P2Y11 1321N1/P2Y11
P2Y12 1321N1/P2Y12/Gα15
Parathyroid hormone receptor PTH1/PTHR1 CHO-K1/PTH1/Gα15
PTH2/PTHR2 293/PTH2/CRE-Luc
Peptide P518 receptor QRFP/GPR103 CHO-K1/GPR103/Gα15
Platelet activating factor receptor PAFR/PTAFR CHO-K1/PTAFR
Prolactin releasing peptide receptor PRLHR CHO-K1/PRLHR
Prostanoid receptor DP2 CHO-K1/DP2/Gα15
EP1/PTGER1 293/EP1
EP2/PTGER2 CHO-K1/EP2/Gα15
FP/PTGFR 293/FP/Gα15
IP1/PTGIR CHO-K1/IP1/Gα15
TP/TBXA2R 293/TP
PTGDR/DP1 CHO-K1/DP1/Gα15
Proteinase-activated receptor PAR2 CHO-K1/PAR2/Gα15
PAR4/F2RL3 CHO-K1/PAR4

Back to the top


Family
Receptor
Cell Line
Cat.No.
Somatostatin receptor SST1 CHO-K1/SST1/Gqi5
SST2/SSTR2 CHO-K1/SST2/Gα15
SST3 CHO-K1/SST3/Gα15
SST4/SSTR4 CHO-K1/SST4/Gα15
SST5/SSTR5 CHO-K1/SST5/Gα15
Tachykinin receptor NK1/TACR1 CHO-K1/NK1
NK2/TACR2 CHO-K1/NK2
NK3/TACR3 CHO-K1/NK3
Thyrtropin releasing hormone receptor TRH1/TRHR CHO-K1/TRH1
Urotensin receptor UTR2 CHO-K1/UT2/Gα15
Vasopressin and oxytocin receptor OT/OXTR CHO-K1/OXTR
V1B CHO-K1/V1B
V2 CHO-K1/V2/Gα15
VIP and PACAP receptor PAC1 CHO-K1/PAC1/Gα15
VPAC2 CHO-K1/VPAC2/Gα15
VPAC1/VIP1 CHO-K1/VPAC1/Gα15
VIPR2 CHO-K1/CRE-Luc/VPAC2  New
Control \ CHO-K1/CRE/Luc
\ CHO-K1/Gα15
\ CHO-K1/Gqi5
\ HEK293/Gα15   New

Back to the top

 
*
*
*
*