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Stable Cell Lines

Immune Checkpoint Stable Cell Lines

Inhibitors of immune-checkpoint proteins, such as PD1, PD-L1, VISTA, Tim3 and Lag3, have indicated broad and diverse opportunities to increase antitumor immunity by enhancing T cell activity with the potential to produce durable clinical responses. To meet these needs, we have developed stable cell line products expressing the most popular immune checkpoints to accelerate your immunotherapy drug discovery and achieve US Food and Drug Administration (FDA) approval. All these stable cells are developed for screening high affinity antibodies against immune checkpoint proteins.

Key features

Product list

Receptor Cell Line Cat.No. Price
CD27 GS-H2/CD27 Quote
CD28 GS-J1/CD28 Quote
CD40 GS-H2/CD40 Quote
CD80 GS-C1/CD80 Quote
GITR GS-H2/GITR Quote

Fc Receptor Cell Lines

Product list

Receptor Cell Line Cat.No.
CD16 CHO-K1/CD16B
CD32A CHO-K1/CD32A 131His
CHO-K1/CD32A 131Arg
CD32B CHO-K1/CD32B 232Ile
CHO-K1/CD32B 232Thr
CD32C CHO-K1/CD32C 13Gln
CD64 CHO-K1/CD64
FcRn CHO-K1/FcRn

GPCR & Ion Channel Stable Cell Lines

GenScript offers a wide selection of GPCR & ion channel stable cell lines. Proprietary codon optimization and vector design technologies enable GenScript to overcome low functional protein expression at the cell surface. All of the cell lines have been optimized for S/B ratio in calcium flux assays, FRET assays, or chemiluminescent assays. They are shown to be stable for 16 passages.

Key features

  • High functional protein expression at the cell surface
  • Stable cell lines for increased reliability and reproducibility
  • Flexible functional readouts are available

Product list

 
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