Overview

GenCRISPR synthetic sgRNAs are proven effective for targeted gene editing in knockout and HDR mediated knock-in experiments. Using sgRNA with Cas9 protein in the ribonucleic protein (RNP) system offers additional advantages over traditional plasmid or virus based delivery systems.

Advantages

Ready-to-use sgRNA, no IVT or annealing required
Detectable at high levels shortly after transfection
DNA free / transgene-free
Quickly cleared from the cell for less off-target effects
Suitable for both ex and in vivo studies
Highly efficient even in difficult primary cell types

Available in multiple grades to support your editing needs

Resources

CRISPR RNA FAQs

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