Overview

About the Cellular responses to stress pathway

Cells are subject to external molecular and physical stresses such as foreign molecules that perturb metabolic or signaling processes, and changes in temperature or pH. The ability of cells and tissues to modulate molecular processes in response to such external stresses is essential to the maintenance of tissue homeostasis (Kultz 2005).

The longest variant of each gene is displayed. Click the see gene variants link to see all gene variants.

378 gene Click for more »

Gene Symbol Full Name
AQP8 aquaporin 8
ARNT aryl hydrocarbon receptor nuclear translocator
ATM ATM serine/threonine kinase
ATOX1 antioxidant 1 copper chaperone
ATP7A ATPase, Cu++ transporting, alpha polypeptide
ATR ATR serine/threonine kinase
BAG1 BCL2-associated athanogene
BMI1 BMI1 proto-oncogene, polycomb ring finger
CA9 carbonic anhydrase IX
CAMK2A calcium/calmodulin-dependent protein kinase II alpha
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CAMK2D calcium/calmodulin-dependent protein kinase II delta
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CAT catalase
CCNA2 cyclin A2
CCNE1 cyclin E1
CDC27 cell division cycle 27
CDK2 cyclin-dependent kinase 2
CDK4 cyclin-dependent kinase 4
CDK6 cyclin-dependent kinase 6
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CREBBP CREB binding protein
MAPK14 mitogen-activated protein kinase 14
E2F1 E2F transcription factor 1
E2F2 E2F transcription factor 2
E2F3 E2F transcription factor 3
PHC1 polyhomeotic homolog 1 (Drosophila)
PHC2 polyhomeotic homolog 2 (Drosophila)
EEF1A1 eukaryotic translation elongation factor 1 alpha 1
EP300 E1A binding protein p300
EPAS1 endothelial PAS domain protein 1
EPO erythropoietin
ERF Ets2 repressor factor
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
FKBP4 FK506 binding protein 4, 59kDa
FOS FBJ murine osteosarcoma viral oncogene homolog
MTOR mechanistic target of rapamycin (serine/threonine kinase)
GPX1 glutathione peroxidase 1
GPX2 glutathione peroxidase 2
GPX3 glutathione peroxidase 3
GPX7 glutathione peroxidase 7
GSK3B glycogen synthase kinase 3 beta
GSR glutathione reductase
GSTP1 glutathione S-transferase pi 1
H1F0 H1 histone family, member 0
HIST1H1C histone cluster 1, H1c
HIST1H1D histone cluster 1, H1d
HIST1H1E histone cluster 1, H1e
HIST1H1B histone cluster 1, H1b
HIST1H2AE histone cluster 1, H2ae
HIST1H2AD histone cluster 1, H2ad
H2AFX H2A histone family, member X
H2AFZ H2A histone family, member Z
HIST1H2BD histone cluster 1, H2bd
HIST1H2BB histone cluster 1, H2bb
H3F3A H3 histone, family 3A
H3F3B H3 histone, family 3B (H3.3B)
HIST1H1A histone cluster 1, H1a
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HMGA1 high mobility group AT-hook 1
HSBP1 heat shock factor binding protein 1
HSF1 heat shock transcription factor 1
HSPA1A heat shock 70kDa protein 1A
HSPA1B heat shock 70kDa protein 1B
HSPA1L heat shock 70kDa protein 1-like
HSPA2 heat shock 70kDa protein 2
HSPA4 heat shock 70kDa protein 4
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPA7 heat shock 70kDa protein 7 (HSP70B)
HSPA8 heat shock 70kDa protein 8
HSPA9 heat shock 70kDa protein 9 (mortalin)
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IFNB1 interferon, beta 1, fibroblast
IGFBP7 insulin-like growth factor binding protein 7
IL1A interleukin 1, alpha
IL6 interleukin 6
CXCL8 chemokine (C-X-C motif) ligand 8
JUN jun proto-oncogene
LMNB1 lamin B1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MOV10 Mov10 RISC complex RNA helicase
MRE11A MRE11 homolog A, double strand break repair nuclease
NBN nibrin
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NUP88 nucleoporin 88kDa
NUP98 nucleoporin 98kDa
P4HB prolyl 4-hydroxylase, beta polypeptide

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