About the Organelle biogenesis and maintenance pathway
This module describes the biogenesis of organelles. Organelles are subcellular structures of distinctive morphology and function. The organelles of human cells include: mitochondria, endoplasmic reticulum, Golgi apparatus, vacuoles, nucleus, (auto)phagosome, centriole, lysosome, melanosome, myofibril, nucleolus, peroxisome, cilia (in some cell types), proteasome, ribsome, and transport vesicles.
The longest variant of each gene is displayed. Click the see gene variants link to see all gene variants.
321 gene Click for more »
| Gene Symbol | Full Name |
|---|---|
| ALAS1 | 5'-aminolevulinate synthase 1 |
| ARF4 | ADP-ribosylation factor 4 |
| ARL3 | ADP-ribosylation factor-like 3 |
| ATP5B | ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide |
| BBS1 | Bardet-Biedl syndrome 1 |
| BBS2 | Bardet-Biedl syndrome 2 |
| BBS4 | Bardet-Biedl syndrome 4 |
| MRPL49 | mitochondrial ribosomal protein L49 |
| CDK1 | cyclin-dependent kinase 1 |
| CETN2 | centrin, EF-hand protein, 2 |
| CNGB1 | cyclic nucleotide gated channel beta 1 |
| CNGA2 | cyclic nucleotide gated channel alpha 2 |
| CNGA4 | cyclic nucleotide gated channel alpha 4 |
| CREB1 | cAMP responsive element binding protein 1 |
| ATF2 | activating transcription factor 2 |
| CREBBP | CREB binding protein |
| MAPK14 | mitogen-activated protein kinase 14 |
| CSNK1D | casein kinase 1, delta |
| CSNK1E | casein kinase 1, epsilon |
| DCTN1 | dynactin 1 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 |
| DYNC1I2 | dynein, cytoplasmic 1, intermediate chain 2 |
| ESRRA | estrogen-related receptor alpha |
| GABPA | GA binding protein transcription factor, alpha subunit 60kDa |
| GABPB1 | GA binding protein transcription factor, beta subunit 1 |
| MCHR1 | melanin-concentrating hormone receptor 1 |
| HCFC1 | host cell factor C1 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 |
| ICT1 | immature colon carcinoma transcript 1 |
| KIF3C | kinesin family member 3C |
| TNPO1 | transportin 1 |
| MEF2C | myocyte enhancer factor 2C |
| MEF2D | myocyte enhancer factor 2D |
| RAB8A | RAB8A, member RAS oncogene family |
| MTIF2 | mitochondrial translational initiation factor 2 |
| 42980 | septin 2 |
| NEK2 | NIMA-related kinase 2 |
| NPHP1 | nephronophthisis 1 (juvenile) |
| NRF1 | nuclear respiratory factor 1 |
| ODF2 | outer dense fiber of sperm tails 2 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) |
| PCM1 | pericentriolar material 1 |
| PCNT | pericentrin |
| PDE6D | phosphodiesterase 6D, cGMP-specific, rod, delta |
| PKD1 | polycystic kidney disease 1 (autosomal dominant) |
| PKD2 | polycystic kidney disease 2 (autosomal dominant) |
| PLK1 | polo-like kinase 1 |
| POLRMT | polymerase (RNA) mitochondrial (DNA directed) |
| PPARA | peroxisome proliferator-activated receptor alpha |
| MED1 | mediator complex subunit 1 |
| PPP2R1A | protein phosphatase 2, regulatory subunit A, alpha |
| PRKAA2 | protein kinase, AMP-activated, alpha 2 catalytic subunit |
| PRKAB1 | protein kinase, AMP-activated, beta 1 non-catalytic subunit |
| PRKAB2 | protein kinase, AMP-activated, beta 2 non-catalytic subunit |
| PRKACA | protein kinase, cAMP-dependent, catalytic, alpha |
| PRKAG1 | protein kinase, AMP-activated, gamma 1 non-catalytic subunit |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta |
| MAPK11 | mitogen-activated protein kinase 11 |
| RHO | rhodopsin |
| RP2 | retinitis pigmentosa 2 (X-linked recessive) |
| MRPL23 | mitochondrial ribosomal protein L23 |
| MRPL12 | mitochondrial ribosomal protein L12 |
| MRPS12 | mitochondrial ribosomal protein S12 |
| RXRA | retinoid X receptor, alpha |
| MAPK12 | mitogen-activated protein kinase 12 |
| SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 |
| SMO | smoothened, frizzled class receptor |
| SSBP1 | single-stranded DNA binding protein 1, mitochondrial |
| SSTR3 | somatostatin receptor 3 |
| TBL1X | transducin (beta)-like 1X-linked |
| TCP1 | t-complex 1 |
| TCTE3 | t-complex-associated-testis-expressed 3 |
| TFAM | transcription factor A, mitochondrial |
| CCT3 | chaperonin containing TCP1, subunit 3 (gamma) |
| TUBA4A | tubulin, alpha 4a |
| TUBG1 | tubulin, gamma 1 |
| TUFM | Tu translation elongation factor, mitochondrial |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma |
| DAP3 | death associated protein 3 |
| ALMS1 | Alstrom syndrome protein 1 |
| TUBA1A | tubulin, alpha 1a |
| MTERF1 | mitochondrial transcription termination factor 1 |
| IFT88 | intraflagellar transport 88 |
| MKKS | McKusick-Kaufman syndrome |
| OFD1 | oral-facial-digital syndrome 1 |
| SSNA1 | Sjogren syndrome nuclear autoantigen 1 |
| NCOA1 | nuclear receptor coactivator 1 |
| DYNLL1 | dynein, light chain, LC8-type 1 |
| GBF1 | golgi brefeldin A resistant guanine nucleotide exchange factor 1 |
| RAB11A | RAB11A, member RAS oncogene family |
| HDAC3 | histone deacetylase 3 |
| TRIP11 | thyroid hormone receptor interactor 11 |
| KIF3B | kinesin family member 3B |
| MRPL33 | mitochondrial ribosomal protein L33 |
| NR1D1 | nuclear receptor subfamily 1, group D, member 1 |
| NCOR1 | nuclear receptor corepressor 1 |
| IQCB1 | IQ motif containing B1 |
| CEP135 | centrosomal protein 135kDa |
| CEP57 | centrosomal protein 57kDa |
