About the PI3K-Akt signaling pathway pathway
The phosphatidylinositol 3' -kinase(PI3K)-Akt signaling pathway is activated by many types of cellular stimuli or toxic insults and regulates fundamental cellular functions such as transcription, translation, proliferation, growth, and survival.
The longest variant of each gene is displayed. Click the see gene variants link to see all gene variants.
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| Gene Symbol | Full Name |
|---|---|
| AKT1 | v-akt murine thymoma viral oncogene homolog 1 |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 |
| ANGPT1 | angiopoietin 1 |
| ANGPT2 | angiopoietin 2 |
| FASLG | Fas ligand (TNF superfamily, member 6) |
| ATF4 | activating transcription factor 4 |
| BAD | BCL2-associated agonist of cell death |
| CCND1 | cyclin D1 |
| BCL2 | B-cell CLL/lymphoma 2 |
| BCL2L1 | BCL2-like 1 |
| BRCA1 | breast cancer 1, early onset |
| CASP9 | caspase 9, apoptosis-related cysteine peptidase |
| CCND2 | cyclin D2 |
| CCND3 | cyclin D3 |
| CCNE1 | cyclin E1 |
| CD19 | CD19 molecule |
| CDK2 | cyclin-dependent kinase 2 |
| CDK4 | cyclin-dependent kinase 4 |
| CDK6 | cyclin-dependent kinase 6 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) |
| CHAD | chondroadherin |
| CHRM1 | cholinergic receptor, muscarinic 1 |
| CHRM2 | cholinergic receptor, muscarinic 2 |
| CHUK | conserved helix-loop-helix ubiquitous kinase |
| COL1A1 | collagen, type I, alpha 1 |
| COL1A2 | collagen, type I, alpha 2 |
| COL2A1 | collagen, type II, alpha 1 |
| COL3A1 | collagen, type III, alpha 1 |
| COL4A1 | collagen, type IV, alpha 1 |
| COL4A2 | collagen, type IV, alpha 2 |
| COL4A3 | collagen, type IV, alpha 3 (Goodpasture antigen) |
| COL4A4 | collagen, type IV, alpha 4 |
| COL4A5 | collagen, type IV, alpha 5 |
| COL4A6 | collagen, type IV, alpha 6 |
| COL5A1 | collagen, type V, alpha 1 |
| COL5A2 | collagen, type V, alpha 2 |
| COL6A1 | collagen, type VI, alpha 1 |
| COL6A2 | collagen, type VI, alpha 2 |
| COL6A3 | collagen, type VI, alpha 3 |
| COL11A1 | collagen, type XI, alpha 1 |
| COL11A2 | collagen, type XI, alpha 2 |
| COMP | cartilage oligomeric matrix protein |
| CREB1 | cAMP responsive element binding protein 1 |
| ATF2 | activating transcription factor 2 |
| ATF6B | activating transcription factor 6 beta |
| CSF1 | colony stimulating factor 1 (macrophage) |
| CSF1R | colony stimulating factor 1 receptor |
| CSF3 | colony stimulating factor 3 (granulocyte) |
| CSF3R | colony stimulating factor 3 receptor (granulocyte) |
| CSH1 | chorionic somatomammotropin hormone 1 (placental lactogen) |
| CSH2 | chorionic somatomammotropin hormone 2 |
| LPAR1 | lysophosphatidic acid receptor 1 |
| EFNA1 | ephrin-A1 |
| EFNA2 | ephrin-A2 |
| EFNA3 | ephrin-A3 |
| EFNA4 | ephrin-A4 |
| EFNA5 | ephrin-A5 |
| EGF | epidermal growth factor |
| EGFR | epidermal growth factor receptor |
| EPHA2 | EPH receptor A2 |
| EIF4B | eukaryotic translation initiation factor 4B |
| EIF4E | eukaryotic translation initiation factor 4E |
| EIF4EBP1 | eukaryotic translation initiation factor 4E binding protein 1 |
| EPO | erythropoietin |
| EPOR | erythropoietin receptor |
| F2R | coagulation factor II (thrombin) receptor |
| FGF1 | fibroblast growth factor 1 (acidic) |
| FGF2 | fibroblast growth factor 2 (basic) |
| FGF3 | fibroblast growth factor 3 |
| FGF4 | fibroblast growth factor 4 |
| FGF5 | fibroblast growth factor 5 |
| FGF6 | fibroblast growth factor 6 |
| FGF7 | fibroblast growth factor 7 |
| FGF8 | fibroblast growth factor 8 (androgen-induced) |
| FGF9 | fibroblast growth factor 9 |
| FGF10 | fibroblast growth factor 10 |
| FGF11 | fibroblast growth factor 11 |
| FGF12 | fibroblast growth factor 12 |
| FGF13 | fibroblast growth factor 13 |
| FGF14 | fibroblast growth factor 14 |
| FGFR1 | fibroblast growth factor receptor 1 |
| FGFR3 | fibroblast growth factor receptor 3 |
| FGFR2 | fibroblast growth factor receptor 2 |
| FGFR4 | fibroblast growth factor receptor 4 |
| FIGF | c-fos induced growth factor (vascular endothelial growth factor D) |
| FOXO3 | forkhead box O3 |
| FLT1 | fms-related tyrosine kinase 1 |
| FLT4 | fms-related tyrosine kinase 4 |
| FN1 | fibronectin 1 |
| MTOR | mechanistic target of rapamycin (serine/threonine kinase) |
| G6PC | glucose-6-phosphatase, catalytic subunit |
| GH1 | growth hormone 1 |
| GH2 | growth hormone 2 |
| GHR | growth hormone receptor |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 |
| GNB2 | guanine nucleotide binding protein (G protein), beta polypeptide 2 |
| GNB3 | guanine nucleotide binding protein (G protein), beta polypeptide 3 |
| GNG3 | guanine nucleotide binding protein (G protein), gamma 3 |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
