About the Signaling by Rho GTPases pathway
The Rho family of small guanine nucleotide binding proteins is one of five generally recognized branches of the Ras superfamily. Like most Ras superfamily members, typical Rho proteins function as binary switches controlling a variety of biological processes.
The longest variant of each gene is displayed. Click the see gene variants link to see all gene variants.
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| Gene Symbol | Full Name |
|---|---|
| A2M | alpha-2-macroglobulin |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase |
| ABR | active BCR-related |
| ACTB | actin, beta |
| ACTG1 | actin gamma 1 |
| BIRC5 | baculoviral IAP repeat containing 5 |
| KLK3 | kallikrein-related peptidase 3 |
| AR | androgen receptor |
| RHOA | ras homolog family member A |
| RHOB | ras homolog family member B |
| RHOC | ras homolog family member C |
| RHOG | ras homolog family member G |
| ARHGAP1 | Rho GTPase activating protein 1 |
| ARHGAP4 | Rho GTPase activating protein 4 |
| ARHGAP5 | Rho GTPase activating protein 5 |
| ARHGAP6 | Rho GTPase activating protein 6 |
| ARHGDIA | Rho GDP dissociation inhibitor (GDI) alpha |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta |
| ARHGDIG | Rho GDP dissociation inhibitor (GDI) gamma |
| RHOH | ras homolog family member H |
| BCR | breakpoint cluster region |
| BTK | Bruton agammaglobulinemia tyrosine kinase |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase |
| BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B |
| FMNL1 | formin-like 1 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) |
| CALM3 | calmodulin 3 (phosphorylase kinase, delta) |
| CDC20 | cell division cycle 20 |
| CDC25C | cell division cycle 25C |
| CDC42 | cell division cycle 42 |
| CDH1 | cadherin 1, type 1 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) |
| CENPA | centromere protein A |
| CENPC | centromere protein C |
| CENPE | centromere protein E, 312kDa |
| CENPF | centromere protein F, 350/400kDa |
| CFTR | cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) |
| CHN1 | chimerin 1 |
| CHN2 | chimerin 2 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa |
| CYBA | cytochrome b-245, alpha polypeptide |
| CYBB | cytochrome b-245, beta polypeptide |
| DIAPH1 | diaphanous-related formin 1 |
| DIAPH2 | diaphanous-related formin 2 |
| DLG4 | discs, large homolog 4 (Drosophila) |
| DVL1 | dishevelled segment polarity protein 1 |
| DVL2 | dishevelled segment polarity protein 2 |
| DVL3 | dishevelled segment polarity protein 3 |
| ECT2 | epithelial cell transforming 2 |
| CTTN | cortactin |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 |
| FLNA | filamin A, alpha |
| CENPI | centromere protein I |
| GDI1 | GDP dissociation inhibitor 1 |
| GDI2 | GDP dissociation inhibitor 2 |
| SFN | stratifin |
| GRB2 | growth factor receptor-bound protein 2 |
| ARHGAP35 | Rho GTPase activating protein 35 |
| HIST1H2AE | histone cluster 1, H2ae |
| HIST1H2AD | histone cluster 1, H2ad |
| H2AFX | H2A histone family, member X |
| H2AFZ | H2A histone family, member Z |
| HIST1H2BD | histone cluster 1, H2bd |
| HIST1H2BB | histone cluster 1, H2bb |
| H3F3A | H3 histone, family 3A |
| H3F3B | H3 histone, family 3B (H3.3B) |
| NCKAP1L | NCK-associated protein 1-like |
| INCENP | inner centromere protein antigens 135/155kDa |
| INPP5B | inositol polyphosphate-5-phosphatase B |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) |
| KIF2A | kinesin heavy chain member 2A |
| KIF5A | kinesin family member 5A |
| KIF5B | kinesin family member 5B |
| KLK2 | kallikrein-related peptidase 2 |
| KLC1 | kinesin light chain 1 |
| KTN1 | kinectin 1 (kinesin receptor) |
| LIMK1 | LIM domain kinase 1 |
| LIMK2 | LIM domain kinase 2 |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) |
| MCF2 | MCF.2 cell line derived transforming sequence |
| MEN1 | multiple endocrine neoplasia I |
| MYH9 | myosin, heavy chain 9, non-muscle |
| MYH10 | myosin, heavy chain 10, non-muscle |
| MYH11 | myosin, heavy chain 11, smooth muscle |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle |
| MYLK | myosin light chain kinase |
| MYO9A | myosin IXA |
| MYO9B | myosin IXB |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A |
| PPP1R12B | protein phosphatase 1, regulatory subunit 12B |
| NCF2 | neutrophil cytosolic factor 2 |
| NCF4 | neutrophil cytosolic factor 4, 40kDa |
| NCK1 | NCK adaptor protein 1 |
| NF2 | neurofibromin 2 (merlin) |
| NUP98 | nucleoporin 98kDa |
| OCRL | oculocerebrorenal syndrome of Lowe |
| OPHN1 | oligophrenin 1 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) |
