Gene Symbol | SOD1 |
Entrez Gene ID | 403559 |
Full Name | superoxide dismutase 1 |
General protein information |
|
Gene Type | protein-coding |
Organism | Canis lupus familiaris(dog) |
ORF » Species Summary » Canis lupus familiaris » SOD1 cDNA ORF clone
gRNAs
Gene Symbol | SOD1 |
Entrez Gene ID | 403559 |
Full Name | superoxide dismutase 1 |
General protein information |
|
Gene Type | protein-coding |
Organism | Canis lupus familiaris(dog) |
mRNA | Protein | Name |
---|---|---|
NM_001003035.1 | NP_001003035.1 | superoxide dismutase [Cu-Zn] |
Canis lupus familiaris (dog) | SOD1 | NP_001003035.1 |
Gallus gallus (chicken) | SOD1 | NP_990395.1 |
Anopheles gambiae (African malaria mosquito) | CUSOD3 | XP_311594.2 |
Mus musculus (house mouse) | Sod1 | NP_035564.1 |
Caenorhabditis elegans (roundworm) | sod-5 | NP_494779.1 |
Schizosaccharomyces pombe (fission yeast) | sod1 | NP_593163.1 |
Homo sapiens (human) | SOD1 | NP_000445.1 |
Pan troglodytes (chimpanzee) | SOD1 | NP_001009025.1 |
SOD1 | NP_001027976.1 | |
Rattus norvegicus (Norway rat) | Sod1 | NP_058746.1 |
Caenorhabditis elegans (roundworm) | sod-1 | NP_001021956.1 |
Xenopus tropicalis (tropical clawed frog) | sod1 | NP_001016252.1 |
Bos taurus (cattle) | SOD1 | NP_777040.1 |
Saccharomyces cerevisiae (baker's yeast) | SOD1 | NP_012638.1 |
Kluyveromyces lactis | KLLA0E05567g | XP_454197.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_02625 | XP_003721165.1 |
Arabidopsis thaliana (thale cress) | CSD1 | NP_001077494.1 |
Danio rerio (zebrafish) | sod1 | NP_571369.1 |
Drosophila melanogaster (fruit fly) | Sod | NP_001261700.1 |
Eremothecium gossypii | AGOS_AGL321W | NP_986346.2 |
Neurospora crassa | NCU02133 | XP_964291.2 |
Oryza sativa (rice) | Os03g0351500 | NP_001050118.1 |
Oryza sativa (rice) | Os07g0665200 | NP_001060564.1 |
Evidence of a genomic insertion in intron 2 of SOD1 causing allelic drop-out during routine diagnostic testing for canine degenerative myelopathy.
Turba ME, Loechel R, Rombol? E, Gandini G, Gentilini F
Animal genetics48(3)365-368(2017 Jun)
Distribution of superoxide dismutase 1 and glutathione peroxidase 1 in the cyclic canine endometrium.
Santos C, Pires Mdos A, Santos D, Payan-Carreira R
Theriogenology86(3)738-48(2016 Aug)
Variants within the SP110 nuclear body protein modify risk of canine degenerative myelopathy.
Ivansson EL, Megquier K, Kozyrev SV, Mur?n E, K?rberg IB, Swofford R, Koltookian M, Tonomura N, Zeng R, Kolicheski AL, Hansen L, Katz ML, Johnson GC, Johnson GS, Coates JR, Lindblad-Toh K
Proceedings of the National Academy of Sciences of the United States of America113(22)E3091-100(2016 May)
Accumulation and aggregate formation of mutant superoxide dismutase 1 in canine degenerative myelopathy.
Nakamae S, Kobatake Y, Suzuki R, Tsukui T, Kato S, Yamato O, Sakai H, Urushitani M, Maeda S, Kamishina H
Neuroscience303229-40(2015 Sep)
Degenerative myelopathy in German Shepherd Dog: comparison of two molecular assays for the identification of the SOD1:c.118G>A mutation.
Capucchio MT, Spalenza V, Biasibetti E, Bottero MT, Rasero R, Dalmasso A, Sacchi P
Molecular biology reports41(2)665-70(2014 Feb)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
a genomic insertion in intron 2 of SOD1 was found during routine diagnostic testing for canine degenerative myelopathy
Title: Evidence of a genomic insertion in intron 2 of SOD1 causing allelic drop-out during routine diagnostic testing for canine degenerative myelopathy.
The cyclic changes of SOD1 and GPx1 suggest that they may play important roles in endometrial physiology, probably in apoptosis and proliferation.
Title: Distribution of superoxide dismutase 1 and glutathione peroxidase 1 in the cyclic canine endometrium.
Variants within the SP110 nuclear body protein modify risk of canine degenerative myelopathy
Title: Variants within the SP110 nuclear body protein modify risk of canine degenerative myelopathy.
The results of this study support the hypothesis that the cytoplasmic accumulation and aggregate formation of the mutant SOD1 protein
Title: Accumulation and aggregate formation of mutant superoxide dismutase 1 in canine degenerative myelopathy.
The SOD1:c.118G>A mutation could be a useful marker for breeding strategies intending to reduce the incidence of Degenerative myelopathy .
Title: Degenerative myelopathy in German Shepherd Dog: comparison of two molecular assays for the identification of the SOD1:c.118G>A mutation.
The following SOD1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SOD1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCe34309 | |
Clone ID Related Accession (Same CDS sequence) | NM_001003035.1 | |
Accession Version | NM_001003035.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 462bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-19 | |
Organism | Canis lupus familiaris(dog) | |
Product | superoxide dismutase [Cu-Zn] | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF346417.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF346417.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103936001, SAMEA103936002 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGAGATGA AGGCCGTGTG CGTGTTGAAG GGCCAGGGCC CGGTGGAGGG CACCATCCAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001003035.1 |
CDS | 7..468 |
Translation |
Target ORF information:
Target ORF information:
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1 | ATGGAGATGA AGGCCGTGTG CGTGTTGAAG GGCCAGGGCC CGGTGGAGGG CACCATCCAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Evidence of a genomic insertion in intron 2 of SOD1 causing allelic drop-out during routine diagnostic testing for canine degenerative myelopathy. |
Distribution of superoxide dismutase 1 and glutathione peroxidase 1 in the cyclic canine endometrium. |
Variants within the SP110 nuclear body protein modify risk of canine degenerative myelopathy. |
Accumulation and aggregate formation of mutant superoxide dismutase 1 in canine degenerative myelopathy. |
Degenerative myelopathy in German Shepherd Dog: comparison of two molecular assays for the identification of the SOD1:c.118G>A mutation. |