Gene Symbol | PLAT |
Entrez Gene ID | 281407 |
Full Name | plasminogen activator, tissue type |
General protein information |
|
Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
ORF » Species Summary » Bos taurus » PLAT cDNA ORF clone
gRNAs
Gene Symbol | PLAT |
Entrez Gene ID | 281407 |
Full Name | plasminogen activator, tissue type |
General protein information |
|
Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
mRNA | Protein | Name |
---|---|---|
NM_174146.3 | NP_776571.2 | tissue-type plasminogen activator precursor |
Homo sapiens (human) | PLAT | NP_000921.1 |
Canis lupus familiaris (dog) | PLAT | XP_539955.3 |
Bos taurus (cattle) | PLAT | NP_776571.2 |
Rattus norvegicus (Norway rat) | Plat | NP_037283.2 |
Pan troglodytes (chimpanzee) | PLAT | XP_528120.3 |
PLAT | XP_001095260.1 | |
Xenopus tropicalis (tropical clawed frog) | plat | NP_001025574.2 |
Mus musculus (house mouse) | Plat | NP_032898.2 |
Gallus gallus (chicken) | PLAT | XP_004947670.1 |
Danio rerio (zebrafish) | plat | XP_002663097.1 |
Fertilization outcome could be regulated by binding of oviductal plasminogen to oocytes and by releasing of plasminogen activators during interplay between gametes.
Mond?jar I, Grull?n LA, Garc?a-V?zquez FA, Romar R, Coy P
Fertility and sterility97(2)453-61(2012 Feb)
A whole-genome assembly of the domestic cow, Bos taurus.
Zimin AV, Delcher AL, Florea L, Kelley DR, Schatz MC, Puiu D, Hanrahan F, Pertea G, Van Tassell CP, Sonstegard TS, Mar?ais G, Roberts M, Subramanian P, Yorke JA, Salzberg SL
Genome biology10(4)R42(2009)
Plasminogen activator and serine protease inhibitor-E2 (protease nexin-1) expression by bovine granulosa cells in vitro.
Cao M, Sahmi M, Lussier JG, Price CA
Biology of reproduction71(3)887-93(2004 Sep)
Activation of tissue plasminogen activator gene transcription by Neovastat, a multifunctional antiangiogenic agent.
Gingras D, Nyalendo C, Di Tomasso G, Annabi B, B?liveau R
Biochemical and biophysical research communications320(1)205-12(2004 Jul)
Comparative map alignment of BTA27 and HSA4 and 8 to identify conserved segments of genome containing fat deposition QTL.
Sonstegard TS, Garrett WM, Ashwell MS, Bennett GL, Kappes SM, Van Tassell CP
Mammalian genome : official journal of the International Mammalian Genome Society11(8)682-8(2000 Aug)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The plasminogen/plasminogen activator/plasmin system is activated during gamete interaction and regulates the sperm entry into the oocyte.
Title: Fertilization outcome could be regulated by binding of oviductal plasminogen to oocytes and by releasing of plasminogen activators during interplay between gametes.
stage-dependent regulation of granulosa cell PA and SerpinE2 production, consistent with a role in extracellular matrix remodeling during follicle growth
Title: Plasminogen activator and serine protease inhibitor-E2 (protease nexin-1) expression by bovine granulosa cells in vitro.
These results suggest that Neovastat induces tPA gene transcription through activation of the JNK and NFkappaB signaling pathways, leading to an increase of tPA secretion by endothelial cells.
Title: Activation of tissue plasminogen activator gene transcription by Neovastat, a multifunctional antiangiogenic agent.
The following PLAT gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PLAT cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OBa43918 | |
Clone ID Related Accession (Same CDS sequence) | NM_174146.3 | |
Accession Version | NM_174146.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1701bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-19 | |
Organism | Bos taurus(cattle) | |
Product | tissue-type plasminogen activator precursor | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC105348.1. On Feb 26, 2006 this sequence version replaced NM_174146.2. ##Evidence-Data-START## Transcript exon combination :: BC105348.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN03145412, SAMN03145413 [ECO:0000350] ##Evidence-Data-END## |
1 | ATGATGAGCG CAATGAAGAC AGAGTTCCTG TGCGTGCTGC TGCTCTGTGG AGCTGTCTTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_776571.2 |
CDS | 96..1796 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGATGAGCG CAATGAAGAC AGAGTTCCTG TGCGTGCTGC TGCTCTGTGG AGCTGTCTTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Fertilization outcome could be regulated by binding of oviductal plasminogen to oocytes and by releasing of plasminogen activators during interplay between gametes. |
A whole-genome assembly of the domestic cow, Bos taurus. |
Plasminogen activator and serine protease inhibitor-E2 (protease nexin-1) expression by bovine granulosa cells in vitro. |
Activation of tissue plasminogen activator gene transcription by Neovastat, a multifunctional antiangiogenic agent. |
Comparative map alignment of BTA27 and HSA4 and 8 to identify conserved segments of genome containing fat deposition QTL. |