LGALS1 cDNA ORF clone, Bos taurus(cattle)

Gene
Clones
gRNAs

Gene Symbol	LGALS1
Entrez Gene ID	326598
Full Name	galectin 1
General protein information	Preferred Names galectin 1 Names galectin-1 14 kDa lectin S-Lac lectin 1 beta-galactoside-binding lectin L-14-I gal-1 galaptin lactose-binding lectin 1 lectin galactoside-binding soluble 1 lectin, galactoside-binding, soluble, 1 (galectin 1)
Gene Type	protein-coding
Organism	Bos taurus(cattle)

mRNA and Protein(s)

mRNA Protein Name

NM_175782.1 NP_786976.1 galectin-1
Pathways from BioSystems

mRNA	Protein	Name
NM_175782.1	NP_786976.1	galectin-1

Homologies

	LGALS1	NP_001162098.1
Bos taurus (cattle)	LGALS1	NP_786976.1
Danio rerio (zebrafish)	lgals2a	NP_998059.1
Danio rerio (zebrafish)	lgals1l1	XP_005164019.1
Homo sapiens (human)	LGALS1	NP_002296.1
Gallus gallus (chicken)	LGALS1	NP_996788.1
Pan troglodytes (chimpanzee)	LGALS1	XP_003953931.1
Danio rerio (zebrafish)	lgals2b	NP_956808.1
Canis lupus familiaris (dog)	LGALS1	NP_001188417.1
Mus musculus (house mouse)	Lgals1	NP_032521.1
Rattus norvegicus (Norway rat)	Lgals1	NP_063969.1
Xenopus tropicalis (tropical clawed frog)	LOC100485378	XP_002934260.1

Gene Ontology
Bibliography

Related articles in PubMed

The luteotrophic function of galectin-1 by binding to the glycans on vascular endothelial growth factor receptor-2 in bovine luteal cells.
Sano M, Hashiba K, Nio-Kobayashi J, Okuda K
The Journal of reproduction and development61(5)439-48(2015)

Endometrial expression of progesterone-induced blocking factor and galectins-1, -3, -9, and -3 binding protein in the luteal phase and early pregnancy in cattle.
Okumu LA, Fair T, Szekeres-Bartho J, O'Doherty AM, Crowe MA, Roche JF, Lonergan P, Forde N
Physiological genomics43(14)903-10(2011 Jul)

Disaccharide binding to galectin-1: free energy calculations and molecular recognition mechanism.
Echeverria I, Amzel LM
Biophysical journal100(9)2283-92(2011 May)

Characterization of gene expression profiles in early bovine pregnancy using a custom cDNA microarray.
Ishiwata H, Katsuma S, Kizaki K, Patel OV, Nakano H, Takahashi T, Imai K, Hirasawa A, Shiojima S, Ikawa H, Suzuki Y, Tsujimoto G, Izaike Y, Todoroki J, Hashizume K
Molecular reproduction and development65(1)9-18(2003 May)

Crosslinking of mammalian lectin (galectin-1) by complex biantennary saccharides.
Bourne Y, Bolgiano B, Liao DI, Strecker G, Cantau P, Herzberg O, Feizi T, Cambillau C
Nature structural biology1(12)863-70(1994 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Data suggest that galectin-1 and VEGFR-2 are expressed at mid-luteal stages in luteal cells of corpus luteum; galectin-1 binds directly to asparagine-linked glycans (N-glycans) on VEGFR-2 in luteal cells.
Title: The luteotrophic function of galectin-1 by binding to the glycans on vascular endothelial growth factor receptor-2 in bovine luteal cells.

The relative abundance of PIBF, LGALS1, LGALS3, LGALS3BP, and LGALS9 mRNA would display a differential expression pattern in the endometrium.
Title: Endometrial expression of progesterone-induced blocking factor and galectins-1, -3, -9, and -3 binding protein in the luteal phase and early pregnancy in cattle.

The binding affinity and specificity of galectin-1 for eight different beta-galactosyl terminal disaccharides was studied using molecular-dynamics simulations.
Title: Disaccharide binding to galectin-1: free energy calculations and molecular recognition mechanism.

The following LGALS1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the LGALS1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OBa41495	NM_175782.1 Latest version!	Bos taurus galectin 1 (LGALS1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

LGALS1 ( NM_175782.1 ) cDNA ORF clone, Bos taurus(cattle) -> NP_786976.1 Bos taurus galectin 1 (LGALS1), mRNA.

Price & Availability↑

CloneID	OBa41495
Clone ID Related Accession (Same CDS sequence)	NM_175782.1
Accession Version	NM_175782.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 408bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-26
Organism	Bos taurus(cattle)
Product	galectin-1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from X14330.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: X14330.1, AB099039.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03145412, SAMN03145413 [ECO:0000348] ##Evidence-Data-END##

ATGGCTTGTG GTCTGGTCGC CAGCAACCTG AATCTCAAAC CTGGGGAGTG CCTCAGAGTG 
CGGGGCGAGG TGGCCGCAGA CGCCAAGAGC TTCTTGCTGA ACCTGGGCAA AGACGACAAC 
AACCTGTGCC TCCACTTCAA CCCTCGTTTC AACGCGCATG GGGACGTCAA CACCATCGTG 
TGTAACAGCA AGGACGCTGG GGCCTGGGGG GCCGAGCAGA GGGAATCTGC CTTCCCCTTC 
CAGCCTGGAA GTGTCGTGGA GGTATGCATC TCCTTCAACC AGACGGACCT AACCATCAAG 
CTGCCTGATG GATACGAATT CAAGTTCCCC AACCGCCTCA ACCTGGAGGC CATCAACTAC 
CTGTCTGCAG GTGGTGACTT CAAGATCAAG TGTGTGGCCT TTGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_786976.1
CDS	43..450
Translation	MACGLVASNLNLKPGECLRVRGEVAADAKSFLLNLGKDDNNLCLHFNPRFNAHGDVNTIVCNSKDAGAWGAEQRESAFPFQPGSVVEVCISFNQTDLTIKLPDGYEFKFPNRLNLEAINYLSAGGDFKIKCVAFE

Target ORF information:

RefSeq Version	NM_175782.1
Organism	Bos taurus(cattle)
Definition	Bos taurus galectin 1 (LGALS1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_175782.1

ORF Insert Sequence:

ATGGCTTGTG GTCTGGTCGC CAGCAACCTG AATCTCAAAC CTGGGGAGTG CCTCAGAGTG 
CGGGGCGAGG TGGCCGCAGA CGCCAAGAGC TTCTTGCTGA ACCTGGGCAA AGACGACAAC 
AACCTGTGCC TCCACTTCAA CCCTCGTTTC AACGCGCATG GGGACGTCAA CACCATCGTG 
TGTAACAGCA AGGACGCTGG GGCCTGGGGG GCCGAGCAGA GGGAATCTGC CTTCCCCTTC 
CAGCCTGGAA GTGTCGTGGA GGTATGCATC TCCTTCAACC AGACGGACCT AACCATCAAG 
CTGCCTGATG GATACGAATT CAAGTTCCCC AACCGCCTCA ACCTGGAGGC CATCAACTAC 
CTGTCTGCAG GTGGTGACTT CAAGATCAAG TGTGTGGCCT TTGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The luteotrophic function of galectin-1 by binding to the glycans on vascular endothelial growth factor receptor-2 in bovine luteal cells.
The Journal of reproduction and development61(5)439-48(2015)
Sano M,Hashiba K,Nio-Kobayashi J,Okuda K

Endometrial expression of progesterone-induced blocking factor and galectins-1, -3, -9, and -3 binding protein in the luteal phase and early pregnancy in cattle.
Physiological genomics43(14)903-10(2011 Jul)
Okumu LA,Fair T,Szekeres-Bartho J,O'Doherty AM,Crowe MA,Roche JF,Lonergan P,Forde N

Disaccharide binding to galectin-1: free energy calculations and molecular recognition mechanism.
Biophysical journal100(9)2283-92(2011 May)
Echeverria I,Amzel LM

Characterization of gene expression profiles in early bovine pregnancy using a custom cDNA microarray.
Molecular reproduction and development65(1)9-18(2003 May)
Ishiwata H,Katsuma S,Kizaki K,Patel OV,Nakano H,Takahashi T,Imai K,Hirasawa A,Shiojima S,Ikawa H,Suzuki Y,Tsujimoto G,Izaike Y,Todoroki J,Hashizume K

Crosslinking of mammalian lectin (galectin-1) by complex biantennary saccharides.
Nature structural biology1(12)863-70(1994 Dec)
Bourne Y,Bolgiano B,Liao DI,Strecker G,Cantau P,Herzberg O,Feizi T,Cambillau C

REQUEST A QUOTE

EMAIL

[email protected]

PHONE

1-877-436-7274

ONLINE FORM

Online Quote Submission

ONLINE FORM

Online Quote Submission

LGALS1 cDNA ORF clone, Bos taurus(cattle)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

REQUEST A QUOTE

EMAIL

PHONE

ONLINE FORM

ONLINE FORM

SUPPORT

COMPANY

SUPPORT

COMPANY