Gene Symbol | PDGFB |
Entrez Gene ID | 540106 |
Full Name | platelet derived growth factor subunit B |
General protein information |
|
Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
ORF » Species Summary » Bos taurus » PDGFB cDNA ORF clone
Gene Symbol | PDGFB |
Entrez Gene ID | 540106 |
Full Name | platelet derived growth factor subunit B |
General protein information |
|
Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
mRNA | Protein | Name |
---|---|---|
XM_005207338.4 | XP_005207395.1 | platelet-derived growth factor subunit B isoform X1 |
XM_005207339.3 | XP_005207396.1 | platelet-derived growth factor subunit B isoform X1 |
XM_005207340.3 | XP_005207397.1 | platelet-derived growth factor subunit B isoform X2 |
XM_005207339.4 | XP_005207396.1 | platelet-derived growth factor subunit B isoform X1 |
XM_005207338.3 | XP_005207395.1 | platelet-derived growth factor subunit B isoform X1 |
XM_024992036.1 | XP_024847804.1 | platelet-derived growth factor subunit B isoform X2 |
NM_001017953.2 | NP_001017953.2 | platelet-derived growth factor subunit B precursor |
Canis lupus familiaris (dog) | PDGFB | NP_001003383.1 |
Pan troglodytes (chimpanzee) | PDGFB | XP_515140.2 |
PDGFB | XP_001097395.1 | |
Gallus gallus (chicken) | PDGFB | NP_989601.2 |
Danio rerio (zebrafish) | LOC796490 | XP_005171670.1 |
Bos taurus (cattle) | PDGFB | NP_001017953.2 |
Mus musculus (house mouse) | Pdgfb | NP_035187.2 |
Xenopus tropicalis (tropical clawed frog) | pdgfb | XP_002933796.1 |
Homo sapiens (human) | PDGFB | NP_002599.1 |
Rattus norvegicus (Norway rat) | Pdgfb | NP_113712.1 |
The role of PDGF-B/TGF-?1/neprilysin network in regulating endothelial-to-mesenchymal transition in pulmonary artery remodeling.
Song S, Zhang M, Yi Z, Zhang H, Shen T, Yu X, Zhang C, Zheng X, Yu L, Ma C, Liu Y, Zhu D
Cellular signalling28(10)1489-501(2016 Oct)
ERas protein is overexpressed and binds to the activated platelet-derived growth factor ? receptor in bovine urothelial tumour cells associated with papillomavirus infection.
Russo V, Roperto F, Esposito I, Ceccarelli DM, Zizzo N, Leonardi L, Capparelli R, Borzacchiello G, Roperto S
Veterinary journal (London, England : 1997)21244-7(2016 Jun)
Platelet-derived growth factor-B (PDGF-B) induced by hypoxia promotes the survival of pulmonary arterial endothelial cells through the PI3K/Akt/Stat3 pathway.
Li L, Xu M, Li X, Lv C, Zhang X, Yu H, Zhang M, Fu Y, Meng H, Zhou J
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology35(2)441-51(2015)
Compensatory mutants of the bovine papillomavirus E5 protein and the platelet-derived growth factor ? receptor reveal a complex direct transmembrane interaction.
Edwards AP, Xie Y, Bowers L, DiMaio D
Journal of virology87(20)10936-45(2013 Oct)
A whole-genome assembly of the domestic cow, Bos taurus.
Zimin AV, Delcher AL, Florea L, Kelley DR, Schatz MC, Puiu D, Hanrahan F, Pertea G, Van Tassell CP, Sonstegard TS, Mar?ais G, Roberts M, Subramanian P, Yorke JA, Salzberg SL
Genome biology10(4)R42(2009)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
hypoxia increased the expression of platelet-derived growth factor (PDGF) and transforming growth factor-beta1 (TGF-beta1) and decreased the expression of neprilysin (NEP), which contributed to the hypoxia-induced Endothelial-to-mesenchymal transition of pulmonary artery endothelial cells.
Title: The role of PDGF-B/TGF-?1/neprilysin network in regulating endothelial-to-mesenchymal transition in pulmonary artery remodeling.
Data indicate that ERas/PDGFbetaR complex could play a role in the pathogenesis of bovine papillomavirus-associated bladder neoplasia.
Title: ERas protein is overexpressed and binds to the activated platelet-derived growth factor ? receptor in bovine urothelial tumour cells associated with papillomavirus infection.
Study suggest that PDGF-B is induced by hypoxia and protects against apoptosis via the PI3K/Akt/Stat3 signaling pathway.
Title: Platelet-derived growth factor-B (PDGF-B) induced by hypoxia promotes the survival of pulmonary arterial endothelial cells through the PI3K/Akt/Stat3 pathway.
These results provide strong genetic evidence that the transmembrane domains of the E5 protein of bovine papillomavirus 1 and the platelet-derived growth factor beta receptor contact one another directly.
Title: Compensatory mutants of the bovine papillomavirus E5 protein and the platelet-derived growth factor ? receptor reveal a complex direct transmembrane interaction.
Hypoxia enhances PDGF-B paracrine interactions between glomerular endothelial and mesangial cells.
Title: Hypoxia regulates PDGF-B interactions between glomerular capillary endothelial and mesangial cells.
The following PDGFB gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PDGFB cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OBa41000 | |
Clone ID Related Accession (Same CDS sequence) | NM_001017953.2 | |
Accession Version | NM_001017953.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 726bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-05-13 | |
Organism | Bos taurus(cattle) | |
Product | platelet-derived growth factor subunit B precursor | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC151383.1. On Jan 4, 2008 this sequence version replaced NM_001017953.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC151383.1, EH176545.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03145433, SAMN04019637 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGAATCGCT GCTGGGCGCT CTTCCTGTCT CTCTGCTGCT ACCTGCGTCT GGTCAGCGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001017953.2 |
CDS | 2..727 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001017953.2 |
1 | ATGAATCGCT GCTGGGCGCT CTTCCTGTCT CTCTGCTGCT ACCTGCGTCT GGTCAGCGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OBa19943 | |
Clone ID Related Accession (Same CDS sequence) | XM_005207338.4 , XM_005207339.3 , XM_005207339.4 , XM_005207338.3 | |
Accession Version | XM_005207338.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 729bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-05-06 | |
Organism | Bos taurus(cattle) | |
Product | platelet-derived growth factor subunit B isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_037332.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 7, 2018 this sequence version replaced XM_005207338.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Bos taurus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAATCGCT GCTGGGCGCT CTTCCTGTCT CTCTGCTGCT ACCTGCGTCT GGTCAGCGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_005207395.1 |
CDS | 1010..1738 |
Translation |
Target ORF information:
Target ORF information:
|
XM_005207338.4 |
1 | ATGAATCGCT GCTGGGCGCT CTTCCTGTCT CTCTGCTGCT ACCTGCGTCT GGTCAGCGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OBa19943 | |
Clone ID Related Accession (Same CDS sequence) | XM_005207338.4 , XM_005207339.3 , XM_005207339.4 , XM_005207338.3 | |
Accession Version | XM_005207339.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 729bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-01-25 | |
Organism | Bos taurus(cattle) | |
Product | platelet-derived growth factor subunit B isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003103943.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jan 26, 2016 this sequence version replaced XM_005207339.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Bos taurus Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.5 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAATCGCT GCTGGGCGCT CTTCCTGTCT CTCTGCTGCT ACCTGCGTCT GGTCAGCGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_005207396.1 |
CDS | 3814..4542 |
Translation |
Target ORF information:
Target ORF information:
|
XM_005207339.3 |
1 | ATGAATCGCT GCTGGGCGCT CTTCCTGTCT CTCTGCTGCT ACCTGCGTCT GGTCAGCGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OBa19943 | |
Clone ID Related Accession (Same CDS sequence) | XM_005207338.4 , XM_005207339.3 , XM_005207339.4 , XM_005207338.3 | |
Accession Version | XM_005207339.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 729bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-05-06 | |
Organism | Bos taurus(cattle) | |
Product | platelet-derived growth factor subunit B isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_037332.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 7, 2018 this sequence version replaced XM_005207339.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Bos taurus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAATCGCT GCTGGGCGCT CTTCCTGTCT CTCTGCTGCT ACCTGCGTCT GGTCAGCGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_005207396.1 |
CDS | 1011..1739 |
Translation |
Target ORF information:
Target ORF information:
|
XM_005207339.4 |
1 | ATGAATCGCT GCTGGGCGCT CTTCCTGTCT CTCTGCTGCT ACCTGCGTCT GGTCAGCGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OBa19943 | |
Clone ID Related Accession (Same CDS sequence) | XM_005207338.4 , XM_005207339.3 , XM_005207339.4 , XM_005207338.3 | |
Accession Version | XM_005207338.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 729bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-01-25 | |
Organism | Bos taurus(cattle) | |
Product | platelet-derived growth factor subunit B isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003103943.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jan 26, 2016 this sequence version replaced XM_005207338.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Bos taurus Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.5 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAATCGCT GCTGGGCGCT CTTCCTGTCT CTCTGCTGCT ACCTGCGTCT GGTCAGCGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_005207395.1 |
CDS | 3814..4542 |
Translation |
Target ORF information:
Target ORF information:
|
XM_005207338.3 |
1 | ATGAATCGCT GCTGGGCGCT CTTCCTGTCT CTCTGCTGCT ACCTGCGTCT GGTCAGCGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OBa19944 | |
Clone ID Related Accession (Same CDS sequence) | XM_005207340.3 , XM_024992036.1 | |
Accession Version | XM_005207340.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 636bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-01-25 | |
Organism | Bos taurus(cattle) | |
Product | platelet-derived growth factor subunit B isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003103943.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jan 26, 2016 this sequence version replaced XM_005207340.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Bos taurus Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.5 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCTGAGTG ACCACTCCAT CCGTTCCTTC GATGACCTCC AGCGCCTGCT GCATGGAGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_005207397.1 |
CDS | 378..1013 |
Translation |
Target ORF information:
Target ORF information:
|
XM_005207340.3 |
1 | ATGCTGAGTG ACCACTCCAT CCGTTCCTTC GATGACCTCC AGCGCCTGCT GCATGGAGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OBa19944 | |
Clone ID Related Accession (Same CDS sequence) | XM_005207340.3 , XM_024992036.1 | |
Accession Version | XM_024992036.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 636bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-05-06 | |
Organism | Bos taurus(cattle) | |
Product | platelet-derived growth factor subunit B isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_037332.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Bos taurus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCTGAGTG ACCACTCCAT CCGTTCCTTC GATGACCTCC AGCGCCTGCT GCATGGAGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_024847804.1 |
CDS | 1328..1963 |
Translation |
Target ORF information:
Target ORF information:
|
XM_024992036.1 |
1 | ATGCTGAGTG ACCACTCCAT CCGTTCCTTC GATGACCTCC AGCGCCTGCT GCATGGAGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The role of PDGF-B/TGF-?1/neprilysin network in regulating endothelial-to-mesenchymal transition in pulmonary artery remodeling. |
ERas protein is overexpressed and binds to the activated platelet-derived growth factor ? receptor in bovine urothelial tumour cells associated with papillomavirus infection. |
Platelet-derived growth factor-B (PDGF-B) induced by hypoxia promotes the survival of pulmonary arterial endothelial cells through the PI3K/Akt/Stat3 pathway. |
Compensatory mutants of the bovine papillomavirus E5 protein and the platelet-derived growth factor ? receptor reveal a complex direct transmembrane interaction. |
A whole-genome assembly of the domestic cow, Bos taurus. |